Activation of the ACE2/Ang-(1-7)/Mas pathway reduces oxygen-glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction

Neuroscience

Volumn 273, Issue , 2014, Pages 39-51

  Zheng, J ^a,b   Li, G ^a   Chen, S ^a   Bihl, J ^a   Buck, J ^a   Zhu, Y ^b   Xia, H ^c   Lazartigues, E ^c   Chen, Y ^a   Olson, J E ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain edema; Cerebral cortex; Hippocampus; Hypertension; NADPH oxidase; Stroke

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; ANGIOTENSIN[1-7]; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; BRAIN PROTEIN; LOSARTAN; MAS RECEPTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; UNCLASSIFIED DRUG; 7-ALA-ANGIOTENSIN (1-7); ANGIOTENSIN I; ANGIOTENSIN I (1-7); CYBB PROTEIN, MOUSE; DIPEPTIDYL CARBOXYPEPTIDASE; G PROTEIN COUPLED RECEPTOR; GLUCOSE; MEMBRANE PROTEIN; NOX4 PROTEIN, MOUSE; ONCOPROTEIN; PEPTIDE FRAGMENT; PROTO-ONCOGENE PROTEINS C-MAS-1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN EDEMA; BRAIN ISCHEMIA; CELL COUNT; CELL DEATH; CELL DENSITY; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HIPPOCAMPAL CA1 REGION; HORMONE SYNTHESIS; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRATUM RADIATUM; ANALOGS AND DERIVATIVES; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; BRAIN; CEREBROVASCULAR ACCIDENT; COMPLICATION; DEFICIENCY; GENETICS; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUE; TRANSGENIC MOUSE;

ANGIOTENSIN I; ANGIOTENSIN II; ANIMALS; ANOXIA; BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; CA1 REGION, HIPPOCAMPAL; CELL DEATH; CEREBRAL CORTEX; GLUCOSE; MEMBRANE GLYCOPROTEINS; MICE, TRANSGENIC; NADPH OXIDASE; NEURONS; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; STROKE; TISSUE CULTURE TECHNIQUES;

EID: 84901409689     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.04.060     Document Type: Article

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