Angiotensin II slow-pressor hypertension enhances NMDA currents and NOX2-dependent superoxide production in hypothalamic paraventricular neurons

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 304, Issue 12, 2013, Pages

  Wang, Gang ^a   Coleman, Christal G ^a   Chan, June ^a   Faraco, Giuseppe ^a   Marques Lopes, Jose ^a   Milner, Teresa A ^a   Guruju, Mallikarjuna R ^b   Anrather, Josef ^a   Davisson, Robin L ^b,c   Iadecola, Costantino ^a   Pickel, Virginia M ^a  

^a FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c Department of Obstetrics Gynecology   (United States)

Author keywords

Electron microscopy; NADPH oxidase; Nitric oxide; NMDA receptors; Patch clamp; Reactive oxygen species

Indexed keywords

ANGIOTENSIN II; GLYCOPROTEIN GP 91; N ACETYL S NITROSOPENICILLAMINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME LOCALIZATION; HYPERTENSION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WHOLE CELL;

ELECTRON MICROSCOPY; NADPH OXIDASE; NITRIC OXIDE; NMDA RECEPTORS; PATCH CLAMP; REACTIVE OXYGEN SPECIES;

ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; CALCIUM; HYPERTENSION; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, ANIMAL; N-METHYLASPARTATE; NADPH OXIDASE; NEURONS; NITRIC OXIDE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PATCH-CLAMP TECHNIQUES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 84879144136     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00367.2012     Document Type: Article

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