Epidemiology and risk factors

CONTINUUM Lifelong Learning in Neurology

Volumn 17, Issue 6, 2011, Pages 1213-1232

  Elkind, Mitchell S V ^a  

^a NEUROLOGICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA SMOOTH MUSCLE ACTIN; ANTITHROMBOCYTIC AGENT; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; C REACTIVE PROTEIN; CLOPIDOGREL; COLLAGEN TYPE 4; COPEPTIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; CYSTATIN C; DIPYRIDAMOLE; HYDROCHLOROTHIAZIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ORAL CONTRACEPTIVE AGENT; PHOSPHODIESTERASE; PHOSPHODIESTERASE 4D; PRAVASTATIN; SEROTONIN UPTAKE INHIBITOR; TISSUE PLASMINOGEN ACTIVATOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

AFRICAN AMERICAN; ALCOHOL CONSUMPTION; ALZHEIMER DISEASE; AORTIC ARCH ATHEROMA; ATHEROMA; AUTOSOMAL RECESSIVE DISORDER; BASAL GANGLION; BLOOD PRESSURE; BRAIN ATHEROSCLEROSIS; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN ISCHEMIA; CADASIL; CAROTID ARTERY OBSTRUCTION; CEREBRAL AUTOSOMAL RECESSIVE ARTERIOPATHY WITH SUBCORTICAL INFARCT AND LEUKOENCEPHALOPATHY; CHILDHOOD DISEASE; CHLAMYDOPHILA PNEUMONIAE; CHROMOSOME 9P; CHRONIC KIDNEY DISEASE; CIGARETTE SMOKING; CRYPTOGENIC STROKE; CYTOMEGALOVIRUS; DEMENTIA; DIABETES MELLITUS; DIFFUSION WEIGHTED IMAGING; DISEASE CLASSIFICATION; DISEASE DURATION; DRUG DOSE INCREASE; FABRY DISEASE; FATALITY; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC VARIABILITY; GLOMERULUS FILTRATION RATE; HEART ATRIUM FIBRILLATION; HEART INFARCTION; HEART LEFT VENTRICLE ANEURYSM; HELICOBACTER PYLORI; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HISPANIC; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HYPERLIPIDEMIA; IMMOBILIZATION; INFLAMMATION; INFLUENZA; INFLUENZA VACCINATION; INSULIN RESISTANCE; LEUKOENCEPHALOPATHY; MALNUTRITION; MARFAN SYNDROME; METABOLIC SYNDROME X; MICROALBUMINURIA; MIGRAINE WITH AURA; MITRAL VALVE DISEASE; MITRAL VALVE STRAND; MORTALITY; OBESITY; ONSET AGE; PATENT FORAMEN OVALE; PERIODONTAL DISEASE; PREDICTION; PREVALENCE; PROGNOSIS; PROTEIN BLOOD LEVEL; RACE DIFFERENCE; REVIEW; RISK ASSESSMENT; SALT INTAKE; SANITATION; SCORING SYSTEM; SECONDARY PREVENTION; SEDENTARY LIFESTYLE; SEX DIFFERENCE; SICKLE CELL ANEMIA; SILENT STROKE; SPEECH DISORDER; STROKE; STROKE PATIENT; SUBARACHNOID HEMORRHAGE; SYSTOLIC HYPERTENSION; TRANSIENT ISCHEMIC ATTACK; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT INFECTION; VALVULAR HEART DISEASE; WEAKNESS;

EID: 84856102671     PISSN: 10802371     EISSN: 15386899     Source Type: Journal    
DOI: 10.1212/01.CON.0000410031.34477.8d     Document Type: Review

References (61)

1. Easton JD, Saver JL, Albers GW, et al. Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. Stroke 2009; 40(6): 2276-2293.
2. Warach S, Kidwell CS. The redefinition of TIA: the uses and limitations of DWI in acute ischemic cerebrovascular syndromes. Neurology 2004; 62(3): 359-360. (Pubitemid 38200843)
3. Wu CM, McLaughlin K, Lorenzetti DL, et al. Early risk of stroke after transient ischemic attack: a systematic review and meta-analysis. Arch Intern Med 2007; 167(22): 2417-2422. (Pubitemid 350258447)
4. Johnston SC, Rothwell PM, Nguyen-Huynh MN, et al. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet 2007; 369(9558): 283-292. (Pubitemid 46136488)
5. Arsava EM, Ballabio E, Benner T, et al. The Causative Classification of Stroke system: an international reliability and optimization study. Neurology 2010; 75(14): 1277-1284.
6. Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation 2010; 121(7): e46-e215.
7. Broderick J, Brott T, Kothari R, et al. The Greater Cincinnati/Northern Kentucky Stroke Study: preliminary first-ever and total incidence rates of stroke among blacks. Stroke 1998; 29(2): 415-421. (Pubitemid 28086685)
8. Luepker RV, Arnett DK, Jacobs DR Jr, et al. Trends in blood pressure, hypertension control, and stroke mortality: the Minnesota Heart Survey. Am J Med 2006; 119(1): 42-49. (Pubitemid 43117465)
9. El-Saed A, Kuller LH, Newman AB, et al. Geographic variations in stroke incidence and mortality among older populations in four US communities. Stroke 2006; 37(8): 1975-1979. (Pubitemid 44309889)
10. Johnston SC, Mendis S, Mathers CD. Global variation in stroke burden and mortality: estimates from monitoring, surveillance, and modelling. Lancet Neurol 2009; 8(4): 345-354.
11. Yusuf S, Reddy S, Ounpuu S, Anand S. Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization. Circulation 2001; 104(22): 2746-2753. (Pubitemid 33108145)
12. Zhao D, Liu J, Wang W, et al. Epidemiological transition of stroke in China: twenty-one-year observational study from the Sino-MONICA-Beijing Project. Stroke 2008; 39(6): 1668-1674.
13. Cruz-Flores S, Rabinstein A, Biller J, et al; American Heart Association Stroke Council; Council on Cardiovascular Nursing; Council on Epidemiology and Prevention; Council on Quality of Care and Outcomes Research. Racial-ethnic disparities in stroke care: the American experience: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2011; 42(7): 2091-2116.
14. Kleindorfer DO, Khoury J, Moomaw CJ, et al. Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke Study. Stroke 2010; 41(7): 1326-1331.
15. White H, Boden-Albala B, Wang C, et al. Ischemic stroke subtype incidence among whites, blacks and Hispanics: the Northern Manhattan Study. Circulation 2005; 111(10): 1327-1331. (Pubitemid 40389099)
16. Cushman M, Cantrell RA, McClure LA, et al. Estimated 10-year stroke risk by region and race in the United States: geographic and racial differences in stroke risk. Ann Neurol 2008; 64(5): 507-513.
17. Trimble B, Morgenstern LB. Stroke in minorities. Neurol Clin 2008; 26(4): 1177-1190, xi.
18. Schwamm LH, Reeves MJ, Pan W, et al. Race/ethnicity, quality of care, and outcomes in ischemic stroke. Circulation 2010; 121(13): 1492-1501.
19. McWilliams JM, Meara E, Zaslavsky AM, Ayanian JZ. Differences in control of cardiovascular disease and diabetes by race, ethnicity, and education: U.S. trends from 1999 to 2006 and effects of Medicare coverage. Ann Intern Med 2009; 150(8): 505-515.
20. Vermeer SE, Longstreth WT, Koudtsaal PJ. Silent brain infarcts: a systematic review. Lancet Neurol 2007; 6(7): 611-619. (Pubitemid 46921055)
21. Kohara K, Fujisawa M, Ando F, et al. MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: the NILS-LSA Study. Stroke 2003; 34(5): 1130-1135. (Pubitemid 36547502)
22. Victor RG, Ravenell JE, Freeman A, et al. Effectiveness of a barber-based intervention for improving hypertension control in black men: the BARBER-1 study: a cluster randomized trial. Arch Intern Med 2011; 171(4): 342-350.
23. Matarin M, Brown WM, Singleton A, et al. Whole genome analyses suggest ischemic stroke and heart disease share an association with polymorphisms on chromosome 9p2. Stroke 2008; 39: 1586-1589.
24. Gretarsdottir S, Thorleifsson G, Manolescu A, et al. Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke. Ann Neurol 2008; 64(4): 402-409.
25. O'Donnell MJ, Xavier D, Liu L, et al. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet 2010; 376(9735): 112-123.
26. Lawes CM, Bennett DA, Feigin VL, Rodgers A. Blood pressure and stroke: an overview of published reviews [corrected and republished in Stroke 2004; 35(4): 1024]. Stroke 2004; 35(3): 776-785. (Pubitemid 38280858)
27. Sacco RL, Boden-Albala B, Abel G, et al. Race-ethnic disparities in the impact of stroke risk factors: the Northern Manhattan Stroke Study. Stroke 2001; 32(8): 1725-1731. (Pubitemid 32772198)
28. Rothwell PM, Howard SC, Dolan E, et al. Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension. Lancet 2010; 375(9718): 895-905.
29. Tayal AH, Tian M, Kelly KM, et al. Atrial fibrillation detected by mobile cardiac outpatient telemetry in cryptogenic TIA or stroke. Neurology 2008; 71(21): 1696-1701.
30. Ziegler PD, Glotzer TV, Daoud EG, et al. Incidence of newly detected atrial arrhythmias via implantable devices in patients with a history of thromboembolic events. Stroke 2010; 41(2): 256-260.
31. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991; 22(8): 983-988.
32. KentDM, Thaler DE. Is patent foramen ovale a modifiable risk factor for stroke recurrence? Stroke 2010; 41(suppl 10): S26-S30.
33. Emerging Risk Factors Collaboration; Di Angelantonio E, Sarwar N, Perry P, et al. Major lipids, apolipoproteins, and risk of vascular disease. JAMA 2009; 302(18): 1993-2000.
34. Tirschwell DL, Smith NL, Heckbert SR, et al. Association of cholesterol with stroke risk varies in stroke subtypes and patient subgroups. Neurology 2004; 63(10): 1868-1875. (Pubitemid 39532383)
35. Greer DM, Cagliero E, Krakauer EL, et al. Case records of the Massachusetts General Hospital: case 21-2007: a 58-year-old woman with headaches, weakness, and strokelike episodes. N Engl J Med 2007; 357(2): 164-173.
36. Rundek T, Gardener H, Xu Q, et al. Insulin resistance and risk of ischemic stroke among nondiabetic individuals from the Northern Manhattan Study. Arch Neurol 2010; 67(10): 1195-1200.
37. Mottillo S, Filion KB, Genest J, et al. The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. J Am Coll Cardiol 2010; 56(14): 1113-1132.
38. MacClellan LR, Giles WH, Cole J, et al. Probable migraine with visual aura and risk of ischemic stroke: the stroke prevention in young women study. Stroke 2007; 38(9): 2438-2445. (Pubitemid 47329619)
39. Ridker PM, Cushman M, Stampfer MJ, et al. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997; 336(14): 973-979. (Pubitemid 27152782)
40. Everett BM, Glynn RJ, MacFadyen JG, Ridker PM. Rosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER). Circulation 2010; 121(1): 143-150.
41. Elkind MS, Luna JM, Moon YP, et al. High-sensitivity C-reactive protein predicts mortality but not stroke: the Northern Manhattan Study. Neurology 2009; 73(16): 1300-1307.
42. Elkind MS, Tai W, Coates K, et al. High-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2, and outcome after ischemic stroke. Arch Intern Med 2006; 166(19): 2073-2080. (Pubitemid 44631394)
43. Elkind MS, Ramakrishnan P, Moon YP, et al. Infectious burden and risk of stroke: the Northern Manhattan Study. Arch Neurol 2010; 67(1): 33-38.
44. Elkind MSV, Luna JM, Moon YP, et al. Infectious burden and carotid plaque thickness: the Northern Manhattan Study. Stroke 2010; 41(3): e117-e122.
45. Elkind MS, Sciacca RR, Boden-Albala B, et al. Moderate alcohol consumption reduces risk of ischemic stroke: the Northern Manhattan Study. Stroke 2006; 37(1): 13-19. (Pubitemid 43732041)
46. Lee M, Saver JL, Chang KH, et al. Low glomerular filtration rate and risk of stroke: meta-analysis. BMJ 2010; 341: c4249.
47. Lee M, Saver JL, Chang KH, et al. Impact of microalbuminuria on incident stroke: a meta-analysis. Stroke 2010; 41(11): 2625-2631.
48. Khatri M, Wright CB, Nickolas TL, et al. Chronic kidney disease is associated with white matter hyperintensity volume: the Northern Manhattan Study (NOMAS). Stroke 2007; 38(12): 3121-3126. (Pubitemid 350175724)
49. Smoller JW, Allison M, Cochrane BB, et al. Antidepressant use and risk of incident cardiovascular morbidity and mortality among postmenopausal women in the Women's Health Initiative study. Arch Intern Med 2009; 169(22): 2128-2139.
50. Katan M, Fluri F, Morgenthaler NG, et al. Copeptin: a novel, independent prognostic marker in patients with ischemic stroke. Ann Neurol 2009; 66(6): 799-808.
51. Katan M, Nigro N, Fluri F, et al. Stress hormones predict cerebrovascular re-events after transient ischemic attacks. Neurology 2011; 76(6): 563-566.
52. Katan M, Morgenthaler N, Widmer I, et al. Copeptin, a stable peptide derived from the vasopressin precursor, correlates with the individual stress level. Neuro Endocrinol Lett 2008; 29(3): 341-346.
53. Elkind MS. Why now? Moving from stroke risk factors to stroke triggers. Curr Opin Neurol 2007; 20(1): 51-57. (Pubitemid 46090143)
54. Elkind MS, Carty CL, O'Meara ES, et al. Hospitalization for infection and risk of acute ischemic stroke: the Cardiovascular Health Study. Stroke 2011; 42(7): 1851-1856.
55. Smeeth L, Thomas SL, Hall AJ, et al. Risk of myocardial infarction and stroke after acute infection or vaccination. N Engl J Med 2004; 351(25): 2611-2618. (Pubitemid 39628582)
56. Grau AJ, Fischer B, Barth C, et al. Influenza vaccination is associated with a reduced risk of stroke. Stroke 2005; 36(7): 1501-1506. (Pubitemid 40967520)
57. Davis MM, Taubert K, Benin AL, et al. Influenza vaccination as secondary prevention for cardiovascular disease: a science advisory from the American Heart Association/American College of Cardiology. Circulation 2006; 114(14): 1549-1553. (Pubitemid 44527011)
58. Dhamoon MS, Sciacca RR, Rundek T, et al. Recurrent stroke and cardiac risks after first ischemic stroke: the Northern Manhattan Study. Neurology 2006; 66(5): 641-646. (Pubitemid 43739815)
59. Touzé E, Varenne O, Chatellier G, et al. Risk of myocardial infarction and vascular death after transient ischemic attack and ischemic stroke: a systematic review and meta-analysis. Stroke 2005; 36(12): 2748-2755.
60. Sacco RL, Adams R, Albers G, et al; American Heart Association, American Stroke Association Council on Stroke, Council on Cardiovascular Radiology and Intervention, American Academy of Neurology. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Stroke 2006; 37(2): 577-617. (Pubitemid 43732031)
61. Weimar C, Benemann J, Michalski D, et al. Prediction of recurrent stroke and vascular death in patients with transient ischemic attack or nondisabling stroke: a prospective comparison of validated prognostic scores. Stroke 2010; 41(3): 487-493.