A TIGAR-regulated metabolic pathway is critical for protection of brain ischemia

Journal of Neuroscience

Volumn 34, Issue 22, 2014, Pages 7458-7471

  Li, Mei ^a   Sun, Meiling ^a   Cao, Lijuan ^a   Gu, Jin Hua ^a   Ge, Jianbin ^b   Chen, Jieyu ^a   Han, Rong ^a   Qin, Yuan Yuan ^a   Zhou, Zhi Peng ^c   Ding, Yuqiang ^d   Qin, Zheng Hong ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b The Second People's Hospital of Nantong   (China)

^c GUILIN MEDICAL UNIVERSITY   (China)

^d TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Glucose 6 phosphate dehydrogenase; Ischemia reperfusion; Mitochondria; NADPH; Pentose phosphate pathway; TIGAR

Indexed keywords

CASPASE 3; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; LENTIVIRUS VECTOR; MESSENGER RNA; PENTOSE; PEPTIDES AND PROTEINS; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TP53 INDUCED GLYCOLYSIS AND APOPTOSIS REGULATOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BEAM WALK TEST; BRAIN ISCHEMIA; CELL CULTURE; CELL VIABILITY ASSAY; CONTROLLED STUDY; EXPERIMENTAL BEHAVIORAL TEST; FLOW CYTOMETRY; GENETIC TRANSFECTION; GLYCOLYSIS; IMMUNOFLUORESCENCE TEST; IMMUNOGOLD ELECTRON MICROSCOPY; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; MEMBRANE POTENTIAL; METABOLISM; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOCHONDRION; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; ROTAROD TEST; VIRUS INFECTION; WESTERN BLOTTING; Y-MAZE TEST;

GLUCOSE 6-PHOSPHATE DEHYDROGENASE; ISCHEMIA/REPERFUSION; MITOCHONDRIA; NADPH; PENTOSE PHOSPHATE PATHWAY; TIGAR;

ANIMALS; BRAIN ISCHEMIA; CELLS, CULTURED; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED ICR; MITOCHONDRIA; NEURAL PATHWAYS; NEUROPROTECTIVE AGENTS; PROTEINS;

EID: 84901390341     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4655-13.2014     Document Type: Article

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