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Volumn 76, Issue , 2011, Pages 211-216

Control of glycolysis through regulation of PFK1: Old friends and recent additions

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTOKINASE; FRUCTOSE 2,6 BISPHOSPHATE; GLUCOSE; GLUCOSE 6 PHOSPHATE; GLYCOGEN; INSULIN; LACTIC ACID; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; PROTEIN P53;

EID: 84867425035     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2011.76.010868     Document Type: Article
Times cited : (224)

References (42)
  • 1
    • 76249114497 scopus 로고    scopus 로고
    • E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation
    • Almeida A, Bolanos JP, Moncada S. 2010. E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation. Proc Natl Acad Sci 107: 738-741.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 738-741
    • Almeida, A.1    Bolanos, J.P.2    Moncada, S.3
  • 2
    • 0037108709 scopus 로고    scopus 로고
    • High expression of inducible 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase (iPFK-2; PFKFB3) in human cancers
    • Atsumi T, Chesney J, Metz C, Leng L, Donnelly S, Makita Z, Mitchell R, Bucala R. 2002. High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers. Cancer Res 62: 5881-5887.
    • (2002) Cancer Res , vol.62 , pp. 5881-5887
    • Atsumi, T.1    Chesney, J.2    Metz, C.3    Leng, L.4    Donnelly, S.5    Makita, Z.6    Mitchell, R.7    Bucala, R.8
  • 3
    • 33644677951 scopus 로고    scopus 로고
    • Expression of inducible 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase/PFKFB3 isoforms in adipocytes and their potential role in glycolytic regulation
    • Atsumi T, Nishio T, Niwa H, Takeuchi J, Bando H, Shimizu C, Yoshioka N, Bucala R, Koike T. 2005. Expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase/PFKFB3 isoforms in adipocytes and their potential role in glycolytic regulation. Diabetes 54: 3349-3357.
    • (2005) Diabetes , vol.54 , pp. 3349-3357
    • Atsumi, T.1    Nishio, T.2    Niwa, H.3    Takeuchi, J.4    Bando, H.5    Shimizu, C.6    Yoshioka, N.7    Bucala, R.8    Koike, T.9
  • 4
    • 23844517036 scopus 로고    scopus 로고
    • Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2 6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer
    • Bando H, Atsumi T, Nishio T, Niwa H, Mishima S, Shimizu C, Yoshioka N, Bucala R, Koike T. 2005. Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer. Clin Cancer Res 11: 5784-5792.
    • (2005) Clin Cancer Res , vol.11 , pp. 5784-5792
    • Bando, H.1    Atsumi, T.2    Nishio, T.3    Niwa, H.4    Mishima, S.5    Shimizu, C.6    Yoshioka, N.7    Bucala, R.8    Koike, T.9
  • 6
    • 70350575440 scopus 로고    scopus 로고
    • Modulation of intracellular ROS levels by TIGAR controls autophagy
    • Bensaad K, Cheung EC, Vousden KH. 2009. Modulation of intracellular ROS levels by TIGAR controls autophagy. EMBO J 28: 3015-3026.
    • (2009) EMBO J , vol.28 , pp. 3015-3026
    • Bensaad, K.1    Cheung, E.C.2    Vousden, K.H.3
  • 7
    • 0022519497 scopus 로고
    • Expression of the v-src or v-fps oncogene increases fructose 2 6-bisphosphate in chick-embryo fibroblasts. Novel mechanism for the stimulation of glycolysis by retroviruses
    • Bosca L, Mojena M, Ghysdael J, Rousseau GG, Hue L. 1986. Expression of the v-src or v-fps oncogene increases fructose 2,6-bisphosphate in chick-embryo fibroblasts. Novel mechanism for the stimulation of glycolysis by retroviruses. Biochem J 236: 595-599.
    • (1986) Biochem J , vol.236 , pp. 595-599
    • Bosca, L.1    Mojena, M.2    Ghysdael, J.3    Rousseau, G.G.4    Hue, L.5
  • 8
    • 33746037631 scopus 로고    scopus 로고
    • PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells
    • Calvo MN, Bartrons R, Castano E, Perales JC, Navarro-Sabate A, Manzano A. 2006. PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells. FEBS Lett 580: 3308-3314.
    • (2006) FEBS Lett , vol.580 , pp. 3308-3314
    • Calvo, M.N.1    Bartrons, R.2    Castano, E.3    Perales, J.C.4    Navarro-Sabate, A.5    Manzano, A.6
  • 9
    • 0033057367 scopus 로고    scopus 로고
    • An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and theWarburg effect
    • Chesney J, Mitchell R, Benigni F, Bacher M, Spiegel L, Al-Abed Y, Han JH, Metz C, Bucala R. 1999. An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and theWarburg effect. Proc Natl Acad Sci 96: 3047-3052.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 3047-3052
    • Chesney, J.1    Mitchell, R.2    Benigni, F.3    Bacher, M.4    Spiegel, L.5    Al-Abed, Y.6    Han, J.H.7    Metz, C.8    Bucala, R.9
  • 11
    • 36349004121 scopus 로고    scopus 로고
    • Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis
    • Costa Leite T, Da Silva D, Guimaraes Coelho R, Zancan P, Sola-Penna M. 2007. Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis. Biochem J 408: 123-130.
    • (2007) Biochem J , vol.408 , pp. 123-130
    • Costa Leite, T.1    Da Silva, D.2    Guimaraes Coelho, R.3    Zancan, P.4    Sola-Penna, M.5
  • 12
    • 78649632422 scopus 로고    scopus 로고
    • Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease
    • Derdak Z, Lang CH, Villegas KA, Tong M, Mark NM, de la Monte SM, Wands JR. 2011. Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease. J Hepatol 54: 164-172.
    • (2011) J Hepatol , vol.54 , pp. 164-172
    • Derdak, Z.1    Lang, C.H.2    Villegas, K.A.3    Tong, M.4    Mark, N.M.5    de la Monte, S.M.6    Wands, J.R.7
  • 13
    • 9144271769 scopus 로고    scopus 로고
    • Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity
    • Donthi RV, Ye G, Wu C, McClain DA, Lange AJ, Epstein PN. 2004. Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity. J Biol Chem 279: 48085-48090.
    • (2004) J Biol Chem , vol.279 , pp. 48085-48090
    • Donthi, R.V.1    Ye, G.2    Wu, C.3    McClain, D.A.4    Lange, A.J.5    Epstein, P.N.6
  • 14
    • 70149085458 scopus 로고    scopus 로고
    • Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis
    • Garcia M, Pujol A, Ruzo A, Riu E, Ruberte J, Arbos A, Serafin A, Albella B, Feliu JE, Bosch F. 2009. Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis. PLoS Genet 5: e1000615.
    • (2009) PLoS Genet , vol.5
    • Garcia, M.1    Pujol, A.2    Ruzo, A.3    Riu, E.4    Ruberte, J.5    Arbos, A.6    Serafin, A.7    Albella, B.8    Feliu, J.E.9    Bosch, F.10
  • 15
    • 0026065196 scopus 로고
    • Glucose-induced exertional fatigue in muscle phosphofructokinase deficiency
    • Haller RG, Lewis SF. 1991. Glucose-induced exertional fatigue in muscle phosphofructokinase deficiency. New Engl J Med 324: 364-369.
    • (1991) New Engl J Med , vol.324 , pp. 364-369
    • Haller, R.G.1    Lewis, S.F.2
  • 16
    • 67349249403 scopus 로고    scopus 로고
    • The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
    • Herrero-Mendez A, Almeida A, Fernandez E, Maestre C, Moncada S, Bolanos JP. 2009. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1. Nat Cell Biol 11: 747-752.
    • (2009) Nat Cell Biol , vol.11 , pp. 747-752
    • Herrero-Mendez, A.1    Almeida, A.2    Fernandez, E.3    Maestre, C.4    Moncada, S.5    Bolanos, J.P.6
  • 17
    • 0020483680 scopus 로고
    • Fructose 2 6-bisphosphate 2 years after its discovery
    • Hers HG, Van Schaftingen E. 1982. Fructose 2,6-bisphosphate 2 years after its discovery. Biochem J 206: 1-12.
    • (1982) Biochem J , vol.206 , pp. 1-12
    • Hers, H.G.1    Van Schaftingen, E.2
  • 18
    • 77950484849 scopus 로고    scopus 로고
    • Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response
    • Huo Y, Guo X, Li H, Wang H, ZhangW, Wang Y, Zhou H, Gao Z, Telang S, Chesney J, et al. 2010. Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response. J Biol Chem 285: 3713-3721.
    • (2010) J Biol Chem , vol.285 , pp. 3713-3721
    • Huo, Y.1    Guo, X.2    Li, H.3    Wang, H.4    Zhang, W.5    Wang, Y.6    Zhou, H.7    Gao, Z.8    Telang, S.9    Chesney, J.10
  • 19
    • 79953321019 scopus 로고    scopus 로고
    • Reversible high affinity inhibition of phosphofructokinase-1 by acyl-CoA: A mechanism integrating glycolytic flux with lipid metabolism
    • Jenkins CM, Yang J, Sims HF, GrossRW. 2011. Reversible high affinity inhibition of phosphofructokinase-1 by acyl-CoA: A mechanism integrating glycolytic flux with lipid metabolism. J Biol Chem 286: 11937-11950.
    • (2011) J Biol Chem , vol.286 , pp. 11937-11950
    • Jenkins, C.M.1    Yang, J.2    Sims, H.F.3    Gross, R.W.4
  • 20
    • 38049077430 scopus 로고    scopus 로고
    • 6- Phosphofructo-2-kinase/fructose-2 6-bisphosphatase (PFKFB3) is up-regulated in high-grade astrocytomas
    • Kessler R, Bleichert F, Warnke JP, Eschrich K. 2008. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is up-regulated in high-grade astrocytomas. J Neurooncol 86: 257-264.
    • (2008) J Neurooncol , vol.86 , pp. 257-264
    • Kessler, R.1    Bleichert, F.2    Warnke, J.P.3    Eschrich, K.4
  • 22
    • 0025854920 scopus 로고
    • Regulation of 6-phosphofructo-1-kinase activity in ras-transformed rat-1 fibroblasts
    • Kole HK, Resnick RJ, Van Doren M, Racker E. 1991. Regulation of 6-phosphofructo-1-kinase activity in ras-transformed rat-1 fibroblasts. Arch Biochem Biophys 286: 586-590.
    • (1991) Arch Biochem Biophys , vol.286 , pp. 586-590
    • Kole, H.K.1    Resnick, R.J.2    Van Doren, M.3    Racker, E.4
  • 23
    • 59449084996 scopus 로고    scopus 로고
    • Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator)
    • Li H, Jogl G. 2009. Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator). J Biol Chem 284: 1748-1754.
    • (2009) J Biol Chem , vol.284 , pp. 1748-1754
    • Li, H.1    Jogl, G.2
  • 24
    • 77951298866 scopus 로고    scopus 로고
    • An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-b-D-ribo-pentofuranosyl) cytosine (ECyd), elicits antitumor effect via TP53-induced glycolysis and apoptosis regulator (TIGAR) downregulation
    • Lui VW, Lau CP, Cheung CS, Ho K, Ng MH, Cheng SH, Hong B, Tsao SW, Tsang CM, Lei KI, et al. 2010. An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-b-D-ribo-pentofuranosyl) cytosine (ECyd), elicits antitumor effect via TP53-induced glycolysis and apoptosis regulator (TIGAR) downregulation. Biochem Pharmacol 79: 1772-1780.
    • (2010) Biochem Pharmacol , vol.79 , pp. 1772-1780
    • Lui, V.W.1    Lau, C.P.2    Cheung, C.S.3    Ho, K.4    Ng, M.H.5    Cheng, S.H.6    Hong, B.7    Tsao, S.W.8    Tsang, C.M.9    Lei, K.I.10
  • 27
    • 0037163076 scopus 로고    scopus 로고
    • The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase
    • Marsin AS, Bouzin C, Bertrand L, Hue L. 2002. The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase. J Biol Chem 277: 30778-30783.
    • (2002) J Biol Chem , vol.277 , pp. 30778-30783
    • Marsin, A.S.1    Bouzin, C.2    Bertrand, L.3    Hue, L.4
  • 28
    • 0242710750 scopus 로고    scopus 로고
    • Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase gene family (PFKFB-1-4) expression in vivo
    • Minchenko O, Opentanova I, Caro J. 2003. Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo. FEBS Lett 554: 264-270.
    • (2003) FEBS Lett , vol.554 , pp. 264-270
    • Minchenko, O.1    Opentanova, I.2    Caro, J.3
  • 29
    • 79551469518 scopus 로고    scopus 로고
    • Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 2 in prostate cancer cells
    • Moon JS, Jin WJ, Kwak JH, Kim HJ, Yun MJ, Kim JW, Park SW, Kim KS. 2010. Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells. Biochem J 433: 225-233.
    • (2010) Biochem J , vol.433 , pp. 225-233
    • Moon, J.S.1    Jin, W.J.2    Kwak, J.H.3    Kim, H.J.4    Yun, M.J.5    Kim, J.W.6    Park, S.W.7    Kim, K.S.8
  • 31
    • 40449137922 scopus 로고    scopus 로고
    • Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase
    • Mukhtar MH, Payne VA, Arden C, Harbottle A, Khan S, Lange AJ, Agius L. 2008. Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Am J Physiol Regul Integr Comp Physiol 294: R766-R774.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Mukhtar, M.H.1    Payne, V.A.2    Arden, C.3    Harbottle, A.4    Khan, S.5    Lange, A.J.6    Agius, L.7
  • 33
    • 0029072027 scopus 로고
    • Mutations in muscle phosphofructokinase gene
    • Raben N, Sherman JB. 1995. Mutations in muscle phosphofructokinase gene. Hum Mutat 6: 1-6.
    • (1995) Hum Mutat , vol.6 , pp. 1-6
    • Raben, N.1    Sherman, J.B.2
  • 34
    • 77951024214 scopus 로고    scopus 로고
    • Filamentous actin and its associated binding proteins are the stimulatory site for 6-phosphofructo-1-kinase association within the membrane of human erythrocytes
    • Real-Hohn A, Zancan P, Da Silva D, Martins ER, Salgado LT, Mermelstein CS, Gomes AM, Sola-Penna M. 2010. Filamentous actin and its associated binding proteins are the stimulatory site for 6-phosphofructo-1-kinase association within the membrane of human erythrocytes. Biochimie 92: 538-544.
    • (2010) Biochimie , vol.92 , pp. 538-544
    • Real-Hohn, A.1    Zancan, P.2    Da Silva, D.3    Martins, E.R.4    Salgado, L.T.5    Mermelstein, C.S.6    Gomes, A.M.7    Sola-Penna, M.8
  • 35
    • 4344618856 scopus 로고    scopus 로고
    • 6- Phosphofructo-2-kinase/fructose-2 6-bisphosphatase: Head-to-head with a bifunctional enzyme that controls glycolysis
    • Rider MH, Bertrand L, Vertommen D, Michels PA, Rousseau GG, Hue L. 2004. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: Head-to-head with a bifunctional enzyme that controls glycolysis. Biochem J 381: 561-579.
    • (2004) Biochem J , vol.381 , pp. 561-579
    • Rider, M.H.1    Bertrand, L.2    Vertommen, D.3    Michels, P.A.4    Rousseau, G.G.5    Hue, L.6
  • 37
    • 79955076736 scopus 로고    scopus 로고
    • Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle
    • Tudzarova S, Colombo SL, Stoeber K, Carcamo S, Williams GH, Moncada S. 2011. Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle. Proc Natl Acad Sci 108: 5278-5283.
    • (2011) Proc Natl Acad Sci , vol.108 , pp. 5278-5283
    • Tudzarova, S.1    Colombo, S.L.2    Stoeber, K.3    Carcamo, S.4    Williams, G.H.5    Moncada, S.6
  • 38
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. 1956. On the origin of cancer cells. Science 123: 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 39
    • 0017580461 scopus 로고
    • Enzymology of cancer cells (second of two parts)
    • Weber G. 1977. Enzymology of cancer cells (second of two parts). New Engl J Med 296: 541-551.
    • (1977) New Engl J Med , vol.296 , pp. 541-551
    • Weber, G.1
  • 40
    • 84860667074 scopus 로고    scopus 로고
    • Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer
    • [Epub ahead of print]
    • Won KY, Lim SJ, Kim GY, Kim YW, Han SA, Song JY, Lee DK. 2011. Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer. Hum Pathol [Epub ahead of print].
    • (2011) Hum Pathol
    • Won, K.Y.1    Lim, S.J.2    Kim, G.Y.3    Kim, Y.W.4    Han, S.A.5    Song, J.Y.6    Lee, D.K.7
  • 42
    • 67349131613 scopus 로고    scopus 로고
    • Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatases in cancer
    • Yalcin A, Telang S, Clem B, Chesney J. 2009b. Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer. Exp Mol Pathol 86: 174-179.
    • (2009) Exp Mol Pathol , vol.86 , pp. 174-179
    • Yalcin, A.1    Telang, S.2    Clem, B.3    Chesney, J.4


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