Cross-platform toxicogenomics for the prediction of non-genotoxic hepatocarcinogenesis in rat

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Römer, Michael ^a   Eichner, Johannes ^a   Metzger, Ute ^a   Templin, Markus F ^a   Plummer, Simon ^b,d   Ellinger Ziegelbauer, Heidrun ^c   Zell, Andreas ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b CXR Biosciences Ltd   (United Kingdom)

^c BAYER PHARMA AG   (Germany)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; CYPROTERONE ACETATE; MESSENGER RNA; MICRORNA; PIRINIXIC ACID; THIOACETAMIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENOTOXICITY; HIGH THROUGHPUT SEQUENCING; LEARNING ALGORITHM; LIVER; LIVER CARCINOGENESIS; MACHINE LEARNING; MALE; MICROARRAY ANALYSIS; MOLECULAR INTERACTION; NONHUMAN; PREDICTION; PROTEIN EXPRESSION; RAT; TOXICOGENETICS; ALGORITHM; ANIMAL; AREA UNDER THE CURVE; ARTIFICIAL INTELLIGENCE; BIOLOGY; CARCINOGEN TESTING; CHEMICALLY INDUCED; CHEMISTRY; CLUSTER ANALYSIS; EXPERIMENTAL LIVER NEOPLASM; GENE EXPRESSION REGULATION; METABOLISM; PROCEDURES; PROTEIN MICROARRAY; STATISTICAL MODEL; WISTAR RAT;

ALGORITHMS; ANIMALS; AREA UNDER CURVE; ARTIFICIAL INTELLIGENCE; CARCINOGENICITY TESTS; CARCINOGENS; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MODELS, STATISTICAL; PROTEIN ARRAY ANALYSIS; RATS; RATS, WISTAR; RNA, MESSENGER; TOXICOGENETICS;

EID: 84901362871     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097640     Document Type: Article

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