Engineering nicking enzymes that preferentially nick 5-methylcytosine- modified DNA

Nucleic Acids Research

Volumn 42, Issue 9, 2014, Pages

  Gutjahr, Alice ^a   Xu, Shuang Yong ^a  

^a NEW ENGLAND BIOLABS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLCYTOSINE; BUFFER; DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DNA METHYLTRANSFERASE; GENOMIC DNA; MAGNESIUM ION; METHYL CPG BINDING PROTEIN 2; SODIUM CHLORIDE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; DNA MODIFICATION; DNA SEQUENCE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ENGINEERING; GENE FUSION; GENE TARGETING; GENETIC MARKER; MUTAGENESIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; WILD TYPE;

5-METHYLCYTOSINE; BACILLUS ANTHRACIS; BACILLUS PHAGES; BASE SEQUENCE; CATALYTIC DOMAIN; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA BREAKS, SINGLE-STRANDED; DNA CLEAVAGE; DNA, CIRCULAR; MANGANESE; MOLECULAR SEQUENCE DATA; PLASMIDS; POTASSIUM CHLORIDE; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; SEQUENCE ANALYSIS, DNA; VIRAL PROTEINS;

EID: 84901341739     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku192     Document Type: Article

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