Identification of metabolites, clinical chemistry markers and transcripts associated with hepatotoxicity

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Buness, Andreas ^a   Roth, Adrian ^a   Herrmann, Annika ^a   Schmitz, Oliver ^b   Kamp, Hennicke ^d   Busch, Kristina ^c,d   Suter, Laura ^a,e  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b Metanomics GmbH   (Germany)

^c Metanomics Health GmbH   (Germany)

^d BASF SE   (Germany)

^e UNIVERSITY OF APPLIED SCIENCES AND ARTS NORTHWESTERN SWITZERLAND   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ALPHA GLOBULIN; AMINEPTINE; ASPARTATE AMINOTRANSFERASE; BETA GLOBULIN; BILE ACID; BILIRUBIN; BIOLOGICAL MARKER; CALCIUM; CHLORIDE; CHOLESTEROL; CREATININE; CYCLOSPORIN A; EARLY GROWTH RESPONSE FACTOR 1; ERYTHROMYCIN; GAMMA GLUTAMYLTRANSFERASE; GLIBENCLAMIDE; IDITOL DEHYDROGENASE; IMMUNOGLOBULIN; LACTATE DEHYDROGENASE; PHOSPHATE; POTASSIUM ION; PROTEIN; PUTRESCINE; SODIUM ION; SOMATOMEDIN BINDING PROTEIN 1; TAUROCHOLIC ACID; UNINDEXED DRUG; PLASMA PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL VACUOLE; CONTROLLED STUDY; GAS CHROMATOGRAPHY; GENE EXPRESSION; GENE ONTOLOGY; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; INFLAMMATION; LIQUID CHROMATOGRAPHY; MALE; METABOLOMICS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; RAT; TISSUE LEVEL; TOXIC HEPATITIS; TRANSCRIPTOMICS; ANIMAL; BLOOD; DRUG-INDUCED LIVER INJURY; GENE EXPRESSION PROFILING; LIVER; METABOLISM; PATHOLOGY; PROCEDURES; WISTAR RAT;

ANIMALS; BIOLOGICAL MARKERS; BLOOD PROTEINS; DRUG-INDUCED LIVER INJURY; GENE EXPRESSION PROFILING; LIVER; MALE; METABOLOMICS; RATS; RATS, WISTAR;

EID: 84901303367     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097249     Document Type: Article

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