Diagnostic performance of traditional hepatobiliary biomarkers of drug-induced liver injury in the rat

Toxicological Sciences

Volumn 116, Issue 2, 2010, Pages 397-412

  Ennulat, Daniela ^a   Magid Slav, Michal ^a   Rehm, Sabine ^a   Tatsuoka, Kay S ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

ALP; ALT; AST; Bile acids; Bilirubin; Clinical chemistry; GGT; Hepatotoxicity; Histopathology; Rats; Receiver operating characteristic

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; BILIRUBIN; BIOLOGICAL MARKER; CHOLESTEROL; GAMMA GLUTAMYLTRANSFERASE; TRIACYLGLYCEROL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEPATOBILIARY PARAMETERS; LIVER HISTOLOGY; LIVER NECROSIS; MALE; NONHUMAN; PEROXISOME; RAT; RECEIVER OPERATING CHARACTERISTIC; TOXIC HEPATITIS; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; AREA UNDER THE CURVE; BLOOD; CHEMICALLY INDUCED; CHOLESTASIS; DRUG EFFECTS; HEPATOBILIARY SYSTEM; LIVER; METABOLISM; NECROSIS; PATHOLOGY; SPRAGUE DAWLEY RAT;

ALANINE TRANSAMINASE; ANIMALS; AREA UNDER CURVE; ASPARTATE AMINOTRANSFERASES; BILIARY TRACT; BILIRUBIN; BIOLOGICAL MARKERS; CHOLESTASIS; GAMMA-GLUTAMYLTRANSFERASE; LIVER; MALE; NECROSIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77955085206     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq144     Document Type: Article

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