The protective effect of aged garlic extract on nonsteroidal anti-inflammatory drug-induced gastric inflammations in male albino rats

Evidence-based Complementary and Alternative Medicine

Volumn 2014, Issue , 2014, Pages

  Badr, Gehan Moustafa ^a,b   Al Mulhim, Jawaher Abdulaziz ^a  

^a KING FAISAL UNIVERSITY   (Saudi Arabia)

^b Ain Shams University   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

AGED GARLIC EXTRACT; ANTIOXIDANT; CATALASE; GARLIC EXTRACT; GASTROINTESTINAL MUCOSA PROTECTIVE AGENT; GLUTATHIONE; INDOMETACIN; MALONALDEHYDE; MYELOPEROXIDASE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG EFFECT; DRUG SAFETY; ENZYME ACTIVITY; EXPERIMENTAL GASTRITIS; HISTOPATHOLOGY; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; RAT; SINGLE DRUG DOSE; STOMACH MUCOSA; STOMACH PROTECTION; TREATMENT DURATION;

EID: 84901278213     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2014/759642     Document Type: Article

References (60)

1. Ramaa C. S., Shirode A. R., Mundada A. S., Kadam V. J., Nutraceuticals-an emerging era in the treatment and prevention of cardiovascular diseases. Current Pharmaceutical Biotechnology 2006 7 1 15 23 2-s2.0-33645732837 10.2174/138920106775789647 (Pubitemid 44110362)
2. Karuppiah P., Rajaram S., Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens. Asian Pacific Journal of Tropical Biomedicine 2012 2 8 597 601 2-s2.0-84860632228 10.1016/S2221-1691(12)60104-X
3. Lanzotti V., Barile E., Antignani V., Bonanomi G., Scala F., Antifungal saponins from bulbs of garlic, Allium sativum L. var. Voghiera. Phytochemistry 2012 78 126 134 2-s2.0-84859651121 10.1016/j.phytochem.2012.03.009
4. Şener G., Sehirli Ö., Ipçi Y., Ercan F., Şirvanci S., Gedik N., Yeen B. Ç., Aqueous garlic extract alleviates isehaemia-reperfusion-induced oxidative hepatic injury in rats. Journal of Pharmacy and Pharmacology 2005 57 1 145 150 2-s2.0-11144288619 10.1211/0022357055209 (Pubitemid 40030113)
5. Borek C., Antioxidant health effects of aged garlic extract. Journal of Nutrition 2001 131 3 1010 1015 2-s2.0-0035127376
6. Borek C., Garlic reduces dementia and heart-disease risk. Journal of Nutrition 2006 136 3 810 812 2-s2.0-33644835961
7. Kasuga S., Uda N., Kyo E., Ushijima M., Morihara N., Itakura Y., Pharmacologic activities of aged garlic extract in comparison with other garlic preparations. Journal of Nutrition 2001 131 3 1080 1084 2-s2.0-0035123176
8. Rahman K., Garlic and aging: new insights into an old remedy. Ageing Research Reviews 2003 2 1 39 56 2-s2.0-0344943236 10.1016/S1568-1637(02)00049-1 (Pubitemid 37443917)
9. Amagase H., Clarifying the real bioactive constituents of garlic. Journal of Nutrition 2006 136 3 716 725 2-s2.0-33644835000
10. Zhang X., Tajima K., Kageyama K., Kyoi T., Irsogladine maleate suppresses indomethacin-induced elevation of proinflammatory cytokines and gastric injury in rats. World Journal of Gastroenterology 2008 14 30 4784 4790 2-s2.0-55449119185 10.3748/wjg.14.4784
11. Vemula S. K., Chawada M. B., Thakur K. S., Vahalia M. K., Antiulcer activity of Amlapitta Mishran suspension in rats: a pilot study. Ancient Science of Life 2012 32 2 112 115
12. Abbas A. M., Sakr H. F., Effect of selenium and grape seed extract on indomethacin-induced gastric ulcers in rats. Journal of Physiology and Biochemistry 2013 69 3 527 537
13. Takeuchi K., Pathogenesis of NSAID-induced gastric damage: importance of cyclooxygenase inhibition and gastric hypermotility. World Journal of Gastroenterology 2012 18 18 2147 21460
14. Burke A., Smyth E. M., FitzGerald G. A., Brunton L., Lazo J., Parker K., Analgesic-antipyretic and antiin-inflammatory drugs; pharmacotherapy of gout. Goodman & Gilman's the Pharmacological Basis of therapeutics 2006 11th Columbus, Ohio, USA McGrawHill 671 716
15. Kim J.-H., Kim B.-W., Kwon H.-J., Nam S.-W., Curative effect of selenium against indomethacin-induced gastric ulcers in rats. Journal of Microbiology and Biotechnology 2011 21 4 400 404 2-s2.0-79955786144 10.4014/jmb.1012.12019
16. Itoh M., Guth P. H., Role of oxygen-derived free radicals in hemorrhagic shock-induced gastric lesions in the rat. Gastroenterology 1985 88 5 I 1162 1167 2-s2.0-0021951017 (Pubitemid 15087618)
17. Banerjee R. K., Nonsteroidal anti-inflammatory drugs inhibit gastric peroxidase activity. Biochimica et Biophysica Acta 1990 1034 3 275 280 2-s2.0-0025372015 10.1016/0304-4165(90)90050-7 (Pubitemid 20183634)
18. Das D., Bandyopadhyay D., Bhattacharjee M., Banerjee R. K., Hydroxyl radical is the major causative factor in stress-induced gastric ulceration. Free Radical Biology and Medicine 1997 23 1 8 18 2-s2.0-0031001835 10.1016/S0891-5849(96)00547-3 (Pubitemid 27217003)
19. National Institutes of Health Guide for the Care and Use of Laboratory Animals 1985 Bethesda, Md, USA NIH Publication No. 86-23
20. Bhattacharya S., Banerjee D., Bauri A. K., Chattopadhyay S., Bandyopadhyay S. K., Healing property of the Piper betel phenol, allylpyrocatechol against indomethacin-induced stomach ulceration and mechanism of action. World Journal of Gastroenterology 2007 13 27 3705 3713 2-s2.0-34547667387 (Pubitemid 47207731)
21. Shah A. H., Khan Z. A., Baig M. Z. A., Qureshi S., Al-Bekairi A. M., Gastroprotective effects of pretreatment with Zizyphus sativa fruits against toxic damage in rats. Fitoterapia 1997 68 3 226 234 2-s2.0-0030742406 (Pubitemid 27315801)
22. Hosseinzadeh H., Fazly Bazzaz B. S., Haghi M. M., Antibacterial activity of total extracts and essential oil of Nigella sativa L. seeds in mice. Pharmacologyonline 2007 2 429 435 2-s2.0-34548661065 (Pubitemid 47412864)
23. Brzozowski T., Zwolinska-Wcislo M., Konturek P. C., Kwiecien S., Drozdowicz D., Konturek S. J., Stachura J., Budak A., Bogdal J., Pawlik W. W., Hahn E. G., Influence of gastric colonization with Candida albicans on ulcer healing in rats: effect of ranitidine, aspirin and probiotic therapy. Scandinavian Journal of Gastroenterology 2005 40 3 286 296 2-s2.0-20144387415 10.1080/00365520510011524 (Pubitemid 40476459)
24. Bonavida B., Immunomodulatory effect of tumor necrosis factor. Biotherapy 1991 3 2 127 133 2-s2.0-0026087410
25. Ohkawa H., Ohishi N., Yagi K., Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry 1979 95 2 351 358 2-s2.0-0018384650 (Pubitemid 9194347)
26. Sedlak J., Lindsay R. H., Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Analytical Biochemistry 1968 25 192 205 2-s2.0-0014428865
27. Kwiecień S., Brzozowski T., Konturek P. C., Konturek S. J., The role of reactive oxygen species in action of nitric oxide-donors on stress-induced gastric mucosal lesions. Journal of Physiology and Pharmacology 2002 53 4 761 773 2-s2.0-0036908256 (Pubitemid 36014788)
28. Aebi H., Catalase in vitro. Methods in Enzymology 1984 105 121 126 2-s2.0-0021318441 10.1016/S0076-6879(84)05016-3
29. Krawisz J. E., Sharon P., Stenson W. F., Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984 87 6 1344 1350 2-s2.0-0021742157 (Pubitemid 15201434)
30. Suleyman H., Albayrak A., Bilici M., Cadirci E., Halici Z., Different mechanisms in formation and prevention of indomethacin-induced gastric ulcers. Inflammation 2010 33 4 224 234 2-s2.0-77956184396 10.1007/s10753-009-9176-5
31. Yoshikawa T., Naito Y., Kishi A., Tomii T., Kaneko T., Iinuma S., Ichikawa H., Yasuda M., Takahashi S., Kondo M., Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats. Gut 1993 34 6 732 737 2-s2.0-0027322319 (Pubitemid 23185094)
32. Naito Y., Yoshikawa T., Yoshida N., Kondo M., Role of oxygen radical and lipid peroxidation in indomethacin-induced gastric mucosal injury. Digestive Diseases and Sciences 1998 43 9 30 34 2-s2.0-0031695866
33. Pozzoli C., Menozzi A., Grandi D., Solenghi E., Ossiprandi M. C., Zullian C., Bertini S., Cavestro G. M., Coruzzi G., Protective effects of proton pump inhibitors against indomethacin-induced lesions in the rat small intestine. Naunyn-Schmiedeberg's Archives of Pharmacology 2007 374 4 283 291 2-s2.0-33846182671 10.1007/s00210-006-0121-y (Pubitemid 46089466)
34. Pérez Y., Oyárzabal A., Mas R., Molina V., Jiménez S., Protective effect of D-002, a mixture of beeswax alcohols, against indomethacin-induced gastric ulcers and mechanism of action. Journal of Natural Medicines 2013 67 1 182 189
35. Santucci L., Fiorucci S., Giansanti M., Brunori P. M., Di Matteo F. M., Morelli A., Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha. Gut 1994 35 7 909 915 2-s2.0-0028199216 (Pubitemid 24202720)
36. Ding S.-Z., Lam S.-K., Yuen S.-T., Wong B. C.-Y., Hui W.-M., Ho J., Guo X., Cho C.-H., Prostaglandin, tumor necrosis factor α and neutrophils: causative relationship in indomethacin-induced stomach injuries. European Journal of Pharmacology 1998 348 2-3 257 263 2-s2.0-0032496073 10.1016/S0014-2999(98)00162-9 (Pubitemid 28275590)
37. Yamada T., Deitch E., Specian R. D., Perry M. A., Balfour Sartor R., Grisham M. B., Mechanisms of acute and chronic intestinal inflammation induced by indomethacin. Inflammation 1993 17 6 641 662 2-s2.0-0027377232 10.1007/BF00920471 (Pubitemid 23359088)
38. Elliott S. N., Buret A., McKnight W., Miller M. J. S., Wallace J. L., Bacteria rapidly colonize and modulate healing of gastric ulcers in rats. American Journal of Physiology 1998 275 3 G425 G432 2-s2.0-0031682111
39. Moriya K., Miura N. N., Adachi Y., Ohno N., Systemic inflammatory response associated with augmentation and activation of leukocytes in Candida/indomethacin administered mice. Biological and Pharmaceutical Bulletin 2002 25 6 816 822 2-s2.0-0036596630 10.1248/bpb.25.816 (Pubitemid 40036725)
40. Imai J., Ide N., Nagae S., Moriguchi T., Matsuura H., Itakura Y., Antioxidant and radical scavenging effects of aged garlic extract and its constituents. Planta Medica 1994 60 5 417 420 2-s2.0-0028007567 10.1055/s-2006-959522 (Pubitemid 24330767)
41. Sawa T., Nakao M., Akaike T., Ono K., Maeda H., Alkylperoxyl radical-scavenging activity of various flavonoids and other phenolic compounds: implications for the anti-tumor-promoter effect of vegetables. Journal of Agricultural and Food Chemistry 1999 47 2 397 402 2-s2.0-0033045585 10.1021/jf980765e (Pubitemid 29185198)
42. Park J.-H., Park Y. K., Park E., Antioxidative and antigenotoxic effects of garlic (Allium sativum L.) prepared by different processing methods. Plant Foods for Human Nutrition 2009 64 4 244 249 2-s2.0-71449099293 10.1007/s11130-009-0132-1
43. Ryu K., Ide N., Matsuura H., Itakura Y., N α -(1-deoxy-D-fructos-1- yl)-L-arginine, an antioxidant compound identified in aged garlic extract. Journal of Nutrition 2001 131 3 972 976 2-s2.0-0035127029
44. Maldonado P. D., Chánez-Cárdenas M. E., Pedraza-Chaverrí J., Aged garlic extract, garlic powder extract, S-allylcysteine, diallyl sulfide and diallyl disulfide do not interfere with the antibiotic activity of gentamicin. Phytotherapy Research 2005 19 3 252 254 2-s2.0-20444455000 10.1002/ptr.1674 (Pubitemid 40827652)
45. Iwalokun B. A., Ogunledun A., Ogbolu D. O., Bamiro S. B., Jimi-Omojola J., In vitro antimicrobial properties of aqueous garlic extract against multidrug-resistant bacteria and Candida species from Nigeria. Journal of Medicinal Food 2004 7 3 327 333 2-s2.0-4644251540 10.1089/jmf.2004.7.327 (Pubitemid 39299492)
46. Ankri S., Mirelman D., Antimicrobial properties of allicin from garlic. Microbes and Infection 1999 1 2 125 129 2-s2.0-0032715514 10.1016/S1286-4579(99) 80003-3
47. Sasaki J.-I., Kita T., Ishita K., Uchisawa H., Matsue H., Antibacterial activity of garlic powder against Escherichia coli O-157. Journal of Nutritional Science and Vitaminology 1999 45 6 785 790 2-s2.0-0033500185 (Pubitemid 30141303)
48. Matsuura H., Saponins in garlic as modifiers of the risk of cardiovascular disease. Journal of Nutrition 2001 131 3 1000 1005 2-s2.0-0035126265
49. Colín-González A. L., Santana R. A., Silva-Islas C. A., Chánez-Cárdenas M. E., Santamaría A., Maldonado P. D., The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. Oxidative Medicine and Cellular Longevity 2012 2012 12 10.1155/2012/907162 907162
50. Sies H., Oxidative stress: oxidants and antioxidants. Experimental Physiology 1997 82 2 291 295 2-s2.0-0030894162 (Pubitemid 27182306)
51. Ajaikumar K. B., Asheef M., Babu B. H., Padikkala J., The inhibition of gastric mucosal injury by Punica granatum L. (pomegranate) methanolic extract. Journal of Ethnopharmacology 2005 96 1-2 171 176 2-s2.0-9644291471 10.1016/j.jep.2004.09.007 (Pubitemid 39575048)
52. Ide N., Lau B. H. S., S-Allylcysteine attenuates oxidative stress in endothelial cells. Drug Development and Industrial Pharmacy 1999 25 5 619 624 2-s2.0-0032939041 10.1081/DDC-100102217 (Pubitemid 29186294)
53. Maldonado P. D., Barrera D., Medina-Campos O. N., Hernández-Pando R., Ibarra-Rubio M. E., Pedraza-Chaverrí J., Aged garlic extract attenuates gentamicin induced renal damage and oxidative stress in rats. Life Sciences 2003 73 20 2543 2556 2-s2.0-0038429665 10.1016/S0024-3205(03)00609-X (Pubitemid 37098297)
54. Zeybek A., Ercan F., Çetinel Ş., Çikler E., Saglam B., Şener G., Protective effects of aqueous garlic extract in reducing water avoidance stress-induced degeneration of the stomach, ileum, and liver: morphological and biochemical study. Digestive Diseases and Sciences 2007 52 11 2984 2992 2-s2.0-34848871027 10.1007/s10620-006-9086-4 (Pubitemid 47512493)
55. Omurtag G. Z., Güranliolu F. D., Şehirli Ö., Arbak S., Uslu B., Gedik N., Şener G., Protective effect of aqueous garlic extract against naphthalene-induced oxidative stress in mice. Journal of Pharmacy and Pharmacology 2005 57 5 623 630 2-s2.0-17744396712 10.1211/0022357055939 (Pubitemid 40575707)
56. Abdel-Wahhab M. A., Aly S. E., Antioxidants and radical scavenging properties of vegetable extracts in rats fed aflatoxin-contaminated diet. Journal of Agricultural and Food Chemistry 2003 51 8 2409 2414 2-s2.0-0037427262 10.1021/jf0209185
57. El-Beshbishy H. A., Aqueous garlic extract attenuates hepatitis and oxidative stress induced by galactosamine/lipoploysaccharide in rats. Phytotherapy Research 2008 22 10 1372 1379 2-s2.0-55449138253 10.1002/ptr.2505
58. Morihara N., Hayama M., Fujii H., Aged garlic extract scavenges superoxide radicals. Plant Foods for Human Nutrition 2011 66 1 17 21 2-s2.0-79955065006 10.1007/s11130-011-0216-6
59. Lang A., Lahav M., Sakhnini E., Barshack I., Fidder H. H., Avidan B., Bardan E., Hershkoviz R., Bar-Meir S., Chowers Y., Allicin inhibits spontaneous and TNF- α induced secretion of proinflammatory cytokines and chemokines from intestinal epithelial cells. Clinical Nutrition 2004 23 5 1199 1208 2-s2.0-4544226878 10.1016/j.clnu.2004.03.011 (Pubitemid 39243038)
60. Geng Z., Rong Y., Lau B. H. S., S-allyl cysteine inhibits activation of nuclear factor kappa B in human T cells. Free Radical Biology and Medicine 1997 23 2 345 350 2-s2.0-0030924820 10.1016/S0891-5849(97)00006-3 (Pubitemid 27276616)