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Volumn 83, Issue 6, 2014, Pages 656-665

Homology and molecular dynamics models of toll-like receptor 7 protein and its dimerization

Author keywords

homology modeling; ligand docking; molecular dynamics; toll like receptors

Indexed keywords

IMIQUIMOD; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; LIGAND;

EID: 84901195911     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12278     Document Type: Article
Times cited : (12)

References (48)
  • 2
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda K., Akira S., (2005) Toll-like receptors in innate immunity. Int Immunol; 17: 1-14.
    • (2005) Int Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 3
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R., Preston-Hurlburt P., Janeway C.A. Jr, (1997) A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature; 388: 394-397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway, Jr.C.A.3
  • 5
    • 84875425019 scopus 로고    scopus 로고
    • Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
    • Tanji H., Ohto U., Shibata T., Miyake K., Shimizu T., (2013) Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands. Science; 339: 1426-1429.
    • (2013) Science , vol.339 , pp. 1426-1429
    • Tanji, H.1    Ohto, U.2    Shibata, T.3    Miyake, K.4    Shimizu, T.5
  • 6
    • 41649115159 scopus 로고    scopus 로고
    • TLR2 - Promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity
    • Zähringer U., Lindner B., Inamura S., Heine H., Alexander C., (2008) TLR2-promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity. Immunobiology; 213: 205-224.
    • (2008) Immunobiology , vol.213 , pp. 205-224
    • Zähringer, U.1    Lindner, B.2    Inamura, S.3    Heine, H.4    Alexander, C.5
  • 9
    • 24744459433 scopus 로고    scopus 로고
    • Of mice and man: TLR11 (finally) finds profilin
    • Lauw F.N., Caffrey D.R., Golenbock D.T., (2005) Of mice and man: TLR11 (finally) finds profilin. Trends Immunol; 26: 509-511.
    • (2005) Trends Immunol , vol.26 , pp. 509-511
    • Lauw, F.N.1    Caffrey, D.R.2    Golenbock, D.T.3
  • 11
    • 2442565738 scopus 로고    scopus 로고
    • Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors
    • Nishiya T., DeFranco A.L., (2004) Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors. J Biol Chem; 279: 19008-19017.
    • (2004) J Biol Chem , vol.279 , pp. 19008-19017
    • Nishiya, T.1    Defranco, A.L.2
  • 13
    • 77953435969 scopus 로고    scopus 로고
    • Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8
    • Wang D., Precopio M., Lan T., Yu D., Tang J.X., Kandimalla E.R., Agrawal S., (2010) Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8. Mol Cancer Ther; 9: 1788-1797.
    • (2010) Mol Cancer Ther , vol.9 , pp. 1788-1797
    • Wang, D.1    Precopio, M.2    Lan, T.3    Yu, D.4    Tang, J.X.5    Kandimalla, E.R.6    Agrawal, S.7
  • 16
    • 34447632621 scopus 로고    scopus 로고
    • Pharmacokinetics of 852A, an imidazoquinoline Toll-like receptor 7-specific agonist, following intravenous, subcutaneous, and oral administrations in humans
    • Harrison L.I., Astry C., Kumar S., Yunis C., (2007) Pharmacokinetics of 852A, an imidazoquinoline Toll-like receptor 7-specific agonist, following intravenous, subcutaneous, and oral administrations in humans. J Clin Pharmacol; 47: 962-969.
    • (2007) J Clin Pharmacol , vol.47 , pp. 962-969
    • Harrison, L.I.1    Astry, C.2    Kumar, S.3    Yunis, C.4
  • 17
    • 37849002321 scopus 로고    scopus 로고
    • Toll-like receptor 9 (TLR9) agonists in the treatment of cancer
    • Krieg A.M., (2008) Toll-like receptor 9 (TLR9) agonists in the treatment of cancer. Oncogene; 27: 161-167.
    • (2008) Oncogene , vol.27 , pp. 161-167
    • Krieg, A.M.1
  • 19
    • 0031936182 scopus 로고
    • Manzel L (1998) Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds
    • Macfarlane D.E., (1950) Manzel L (1998) Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds. J Immunol Baltim Md; 160: 1122-1131.
    • (1950) J Immunol Baltim Md , vol.160 , pp. 1122-1131
    • MacFarlane, D.E.1
  • 22
    • 37549066665 scopus 로고    scopus 로고
    • Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms
    • Barrat F.J., Meeker T., Chan J.H., Guiducci C., Coffman R.L., (2007) Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms. Eur J Immunol; 37: 3582-3586.
    • (2007) Eur J Immunol , vol.37 , pp. 3582-3586
    • Barrat, F.J.1    Meeker, T.2    Chan, J.H.3    Guiducci, C.4    Coffman, R.L.5
  • 23
    • 78651467836 scopus 로고    scopus 로고
    • A leucine-rich repeat assembly approach for homology modeling of the human TLR5-10 and mouse TLR11-13 ectodomains
    • Wei T., Gong J., Rössle S.C., Jamitzky F., Heckl W.M., Stark R.W., (2011) A leucine-rich repeat assembly approach for homology modeling of the human TLR5-10 and mouse TLR11-13 ectodomains. J Mol Model; 17: 27-36.
    • (2011) J Mol Model , vol.17 , pp. 27-36
    • Wei, T.1    Gong, J.2    Rössle, S.C.3    Jamitzky, F.4    Heckl, W.M.5    Stark, R.W.6
  • 24
    • 67749108047 scopus 로고    scopus 로고
    • Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains
    • Wei T., Gong J., Jamitzky F., Heckl W.M., Stark R.W., Rössle S.C., (2009) Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains. Protein Sci; 18: 1684-1691.
    • (2009) Protein Sci , vol.18 , pp. 1684-1691
    • Wei, T.1    Gong, J.2    Jamitzky, F.3    Heckl, W.M.4    Stark, R.W.5    Rössle, S.C.6
  • 26
    • 0027136282 scopus 로고
    • Comparative protein modelling by satisfaction of spatial restraints
    • Sali A., Blundell T.L., (1993) Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol; 234: 779-815.
    • (1993) J Mol Biol , vol.234 , pp. 779-815
    • Sali, A.1    Blundell, T.L.2
  • 27
    • 0033810049 scopus 로고    scopus 로고
    • Modeling of loops in protein structures
    • Fiser A., Do R.K., Sali A., (2000) Modeling of loops in protein structures. Protein Sci; 9: 1753-1773.
    • (2000) Protein Sci , vol.9 , pp. 1753-1773
    • Fiser, A.1    Do, R.K.2    Sali, A.3
  • 28
    • 0037406141 scopus 로고    scopus 로고
    • Can correct protein models be identified?
    • Wallner B., Elofsson A., (2003) Can correct protein models be identified? Protein Sci; 12: 1073-1086.
    • (2003) Protein Sci , vol.12 , pp. 1073-1086
    • Wallner, B.1    Elofsson, A.2
  • 29
    • 0000243829 scopus 로고
    • PROCHECK: A program to check the stereochemical quality of protein structures
    • Laskowski R.A., MacArthur M.W., Moss D.S., Thornton J.M., (1993) PROCHECK: a program to check the stereochemical quality of protein structures. J Appl Crystallogr; 26: 283-291.
    • (1993) J Appl Crystallogr , vol.26 , pp. 283-291
    • Laskowski, R.A.1    MacArthur, M.W.2    Moss, D.S.3    Thornton, J.M.4
  • 30
    • 39149099199 scopus 로고    scopus 로고
    • The ModFOLD server for the quality assessment of protein structural models
    • McGuffin L.J., (2008) The ModFOLD server for the quality assessment of protein structural models. Bioinforma Oxf Engl; 24: 586-587.
    • (2008) Bioinforma Oxf Engl , vol.24 , pp. 586-587
    • McGuffin, L.J.1
  • 31
    • 54949097750 scopus 로고    scopus 로고
    • MetaMQAP: A meta-server for the quality assessment of protein models
    • Pawlowski M., Gajda M.J., Matlak R., Bujnicki J.M., (2008) MetaMQAP: a meta-server for the quality assessment of protein models. BMC Bioinformatics; 9: 403.
    • (2008) BMC Bioinformatics , vol.9 , pp. 403
    • Pawlowski, M.1    Gajda, M.J.2    Matlak, R.3    Bujnicki, J.M.4
  • 32
    • 3242889054 scopus 로고    scopus 로고
    • Wurst: A protein threading server with a structural scoring function, sequence profiles and optimized substitution matrices
    • Torda A.E., Procter J.B., Huber T., (2004) Wurst: a protein threading server with a structural scoring function, sequence profiles and optimized substitution matrices. Nucleic Acids Res; 32: W532-W535.
    • (2004) Nucleic Acids Res , vol.32
    • Torda, A.E.1    Procter, J.B.2    Huber, T.3
  • 33
    • 63849246525 scopus 로고    scopus 로고
    • Protein structure prediction on the Web: A case study using the Phyre server
    • Kelley L.A., Sternberg M.J.E., (2009) Protein structure prediction on the Web: a case study using the Phyre server. Nat Protoc; 4: 363-371.
    • (2009) Nat Protoc , vol.4 , pp. 363-371
    • Kelley, L.A.1    Sternberg, M.J.E.2
  • 34
    • 68149132088 scopus 로고    scopus 로고
    • Building and assessing atomic models of proteins from structural templates: Learning and benchmarks
    • Vallat B.K., Pillardy J., Májek P., Meller J., Blom T., Cao B., Elber R., (2009) Building and assessing atomic models of proteins from structural templates: learning and benchmarks. Proteins; 76: 930-945.
    • (2009) Proteins , vol.76 , pp. 930-945
    • Vallat, B.K.1    Pillardy, J.2    Májek, P.3    Meller, J.4    Blom, T.5    Cao, B.6    Elber, R.7
  • 36
    • 0031473847 scopus 로고    scopus 로고
    • SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
    • Guex N., Peitsch M.C., (1997) SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis; 18: 2714-2723.
    • (1997) Electrophoresis , vol.18 , pp. 2714-2723
    • Guex, N.1    Peitsch, M.C.2
  • 37
    • 46249092554 scopus 로고    scopus 로고
    • GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation
    • Hess B., Kutzner C., van der Spoel D., Lindahl E., (2008) GROMACS 4: algorithms for highly efficient, load-balanced, and scalable molecular simulation. J Chem Theory Comput; 4: 435-447.
    • (2008) J Chem Theory Comput , vol.4 , pp. 435-447
    • Hess, B.1    Kutzner, C.2    Van Der Spoel, D.3    Lindahl, E.4
  • 39
    • 33645858780 scopus 로고
    • Quantum and statistical mechanical studies of liquids. 10. Transferable intermolecular potential functions for water, alcohols, and ethers. Application to liquid water
    • Jorgensen W.L., (1981) Quantum and statistical mechanical studies of liquids. 10. Transferable intermolecular potential functions for water, alcohols, and ethers. Application to liquid water. J Am Chem Soc; 103: 335-340.
    • (1981) J Am Chem Soc , vol.103 , pp. 335-340
    • Jorgensen, W.L.1
  • 40
    • 0000204247 scopus 로고
    • Sur la téorie du mouvement Brownian
    • Langevin P., (1905) Sur la téorie du mouvement Brownian. Ann Chim Phys; 5: 245.
    • (1905) Ann Chim Phys , vol.5 , pp. 245
    • Langevin, P.1
  • 41
    • 33646940952 scopus 로고
    • Numerical integration of the cartesian equations of motion of a system with constraints: Molecular dynamics of n-alkanes
    • Ryckaert J.-P., Ciccotti G., Berendsen H.J., (1977) Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes. J Comput Phys; 23: 327-341.
    • (1977) J Comput Phys , vol.23 , pp. 327-341
    • Ryckaert, J.-P.1    Ciccotti, G.2    Berendsen, H.J.3
  • 42
    • 0031370977 scopus 로고    scopus 로고
    • LIGSITE: Automatic and efficient detection of potential small molecule-binding sites in proteins
    • Hendlich M., Rippmann F., Barnickel G., (1997) LIGSITE: automatic and efficient detection of potential small molecule-binding sites in proteins. J Mol Graph Model; 15 (359-363): 389.
    • (1997) J Mol Graph Model , vol.15 , Issue.359-363 , pp. 389
    • Hendlich, M.1    Rippmann, F.2    Barnickel, G.3
  • 43
    • 84888296950 scopus 로고    scopus 로고
    • Accessed 30 May 2013
    • Pocket-Finder: Pocket Detection. http://www.modelling.leeds.ac.uk/ pocketfinder/. Accessed 30 May 2013.
    • Pocket-Finder: Pocket Detection
  • 46
    • 33747840389 scopus 로고    scopus 로고
    • GRAMM-X public web server for protein-protein docking
    • Tovchigrechko A., Vakser I.A., (2006) GRAMM-X public web server for protein-protein docking. Nucleic Acids Res; 34: W310-W314.
    • (2006) Nucleic Acids Res , vol.34
    • Tovchigrechko, A.1    Vakser, I.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.