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Volumn 5, Issue 4, 2014, Pages

MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain

Author keywords

ARC; Chemosensitivity; Gastric cancer; MiR 185; RUNX3

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; APOPTOSIS REPRESSOR WITH CASPASE RECRUITMENT DOMAIN; CISPLATIN; DOXORUBICIN; MICRORNA; MICRORNA 185; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; MIRN185 MICRORNA, HUMAN; MUSCLE PROTEIN; NOL3 PROTEIN, HUMAN; RUNX3 PROTEIN, HUMAN;

EID: 84901051015     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.148     Document Type: Article
Times cited : (81)

References (45)
  • 1
    • 73949150127 scopus 로고    scopus 로고
    • Nature meets nurture: Molecular genetics of gastric cancer
    • Milne AN, Carneiro F, O'morain C, Offerhaus G. Nature meets nurture: molecular genetics of gastric cancer. Hum Genet 2009; 126: 615-628.
    • (2009) Hum Genet , vol.126 , pp. 615-628
    • Milne, A.N.1    Carneiro, F.2    O'Morain, C.3    Offerhaus, G.4
  • 2
    • 0033841622 scopus 로고    scopus 로고
    • Molecular mechanisms involved in cisplatin cytotoxicity
    • Jordan P, Carmo-Fonseca M. Molecular mechanisms involved in cisplatin cytotoxicity. Cell Mol Life Sci 2000; 57: 1229-1235.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1229-1235
    • Jordan, P.1    Carmo-Fonseca, M.2
  • 3
    • 13644254794 scopus 로고    scopus 로고
    • Molecular mechanisms of drug resistance
    • Longley D, Johnston P. Molecular mechanisms of drug resistance. J Pathol 2005; 205: 275-292.
    • (2005) J Pathol , vol.205 , pp. 275-292
    • Longley, D.1    Johnston, P.2
  • 4
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • Zhao Y, Samal E, Srivastava D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 2005; 436: 214-220.
    • (2005) Nature , vol.436 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 5
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-866.
    • (2006) Nat Rev Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 6
    • 55549114664 scopus 로고    scopus 로고
    • The miR-15a- miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
    • Bonci D, Coppola V, Musumeci M, Addario A, Giuffrida R, Memeo L et al. The miR-15a- miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 2008; 14: 1271-1277.
    • (2008) Nat Med , vol.14 , pp. 1271-1277
    • Bonci, D.1    Coppola, V.2    Musumeci, M.3    Addario, A.4    Giuffrida, R.5    Memeo, L.6
  • 7
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007; 449: 682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 8
    • 84855543629 scopus 로고    scopus 로고
    • EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers
    • Garofalo M, Romano G, Di Leva G, Nuovo G, Jeon Y-J, Ngankeu A et al. EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers. Nat Med 2011; 18: 74-82.
    • (2011) Nat Med , vol.18 , pp. 74-82
    • Garofalo, M.1    Romano, G.2    Di Leva, G.3    Nuovo, G.4    Jeon, Y.-J.5    Ngankeu, A.6
  • 10
    • 0032574745 scopus 로고    scopus 로고
    • ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases
    • Koseki T, Inohara N, Chen S, Núnẽz G. ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases. Proc Natl Acad Sci 1998; 95: 5156-5160.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 5156-5160
    • Koseki, T.1    Inohara, N.2    Chen, S.3    Núnẽz, G.4
  • 11
    • 79957590101 scopus 로고    scopus 로고
    • Apoptosis repressor with caspase recruitment domain, a multifunctional modulator of cell death
    • Ludwig-Galezowska AH, Flanagan L, Rehm M. Apoptosis repressor with caspase recruitment domain, a multifunctional modulator of cell death. J Cell Mol Med 2011; 15: 1044-1053.
    • (2011) J Cell Mol Med , vol.15 , pp. 1044-1053
    • Ludwig-Galezowska, A.H.1    Flanagan, L.2    Rehm, M.3
  • 12
    • 45849097197 scopus 로고    scopus 로고
    • ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer
    • Mercier I, Vuolo M, Jasmin J-F, Medina CM, Williams M, Mariadason JM et al. ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer. Cell Cycle 2008; 7: 1640-1647.
    • (2008) Cell Cycle , vol.7 , pp. 1640-1647
    • Mercier, I.1    Vuolo, M.2    Jasmin, J.-F.3    Medina, C.M.4    Williams, M.5    Mariadason, J.M.6
  • 13
    • 20044392926 scopus 로고    scopus 로고
    • ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo-and radiation-resistance
    • Mercier I, Vuolo M, Madan R, Xue X, Levalley A, Ashton A et al. ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo-and radiation-resistance. Cell Death Differ 2005; 12: 682-686.
    • (2005) Cell Death Differ , vol.12 , pp. 682-686
    • Mercier, I.1    Vuolo, M.2    Madan, R.3    Xue, X.4    Levalley, A.5    Ashton, A.6
  • 14
    • 58349085110 scopus 로고    scopus 로고
    • Apoptosis repressor with caspase recruitment domain contributes to chemotherapy resistance by abolishing mitochondrial fission mediated by dynaminrelated protein-1
    • Wang J-X, Li Q, Li P-F. Apoptosis repressor with caspase recruitment domain contributes to chemotherapy resistance by abolishing mitochondrial fission mediated by dynaminrelated protein-1. Cancer Res 2009; 69: 492-500.
    • (2009) Cancer Res , vol.69 , pp. 492-500
    • Wang, J.-X.1    Li, Q.2    Li, P.-F.3
  • 15
    • 0036671304 scopus 로고    scopus 로고
    • Phosphorylation by protein kinase CK2: A signaling switch for the caspase-inhibiting protein ARC
    • Li P-F, Li J, Müller E-C, Otto A, Dietz R, von Harsdorf R. Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC. Mol Cell 2002; 10: 247-258.
    • (2002) Mol Cell , vol.10 , pp. 247-258
    • Li, P.-F.1    Li, J.2    Müller, E.-C.3    Otto, A.4    Dietz, R.5    Von Harsdorf, R.6
  • 16
    • 57749203355 scopus 로고    scopus 로고
    • Novel cardiac apoptotic pathway: The dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin
    • Tan W-Q, Wang J-X, Lin Z-Q, Li Y-R, Lin Y, Li P-F. Novel cardiac apoptotic pathway: the dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin. Circulation 2008; 118: 2268-2276.
    • (2008) Circulation , vol.118 , pp. 2268-2276
    • Tan, W.-Q.1    Wang, J.-X.2    Lin, Z.-Q.3    Li, Y.-R.4    Lin, Y.5    Li, P.-F.6
  • 17
    • 37849029183 scopus 로고    scopus 로고
    • P53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC
    • Li Y-Z, Lu D-Y, Tan W-Q, Wang J-X, Li P-F. P53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC. Mol Cell Biol 2008; 28: 564-574.
    • (2008) Mol Cell Biol , vol.28 , pp. 564-574
    • Li, Y.-Z.1    Lu, D.-Y.2    Tan, W.-Q.3    Wang, J.-X.4    Li, P.-F.5
  • 18
    • 84875448499 scopus 로고    scopus 로고
    • Transcription factor Foxo3a prevents apoptosis by regulating calcium through the apoptosis repressor with caspase recruitment domain
    • Lu D, Liu J, Jiao J, Long B, Li Q, Tan W et al. Transcription factor Foxo3a prevents apoptosis by regulating calcium through the apoptosis repressor with caspase recruitment domain. J Biol Chem 2013; 288: 8491-8504.
    • (2013) J Biol Chem , vol.288 , pp. 8491-8504
    • Lu, D.1    Liu, J.2    Jiao, J.3    Long, B.4    Li, Q.5    Tan, W.6
  • 19
    • 34247158646 scopus 로고    scopus 로고
    • Ubiquitination and degradation of the antiapoptotic protein ARC by MDM2
    • Foo RS-Y, Chan LK, Kitsis RN, Bennett MR. Ubiquitination and degradation of the antiapoptotic protein ARC by MDM2. J Biol Chem 2007; 282: 5529-5535.
    • (2007) J Biol Chem , vol.282 , pp. 5529-5535
    • Foo, R.S.-Y.1    Chan, L.K.2    Kitsis, R.N.3    Bennett, M.R.4
  • 20
    • 78751694922 scopus 로고    scopus 로고
    • Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML
    • Carter BZ, Qiu YH, Zhang N, Coombes KR, Mak DH, Thomas DA et al. Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML. Blood 2011; 117: 780-787.
    • (2011) Blood , vol.117 , pp. 780-787
    • Carter, B.Z.1    Qiu, Y.H.2    Zhang, N.3    Coombes, K.R.4    Mak, D.H.5    Thomas, D.A.6
  • 21
    • 68649091698 scopus 로고    scopus 로고
    • RUNX factors in development: Lessons from invertebrate model systems
    • Braun T, Woollard A. RUNX factors in development: Lessons from invertebrate model systems. Blood Cells Mol Dis 2009; 43: 43-48.
    • (2009) Blood Cells Mol Dis , vol.43 , pp. 43-48
    • Braun, T.1    Woollard, A.2
  • 22
    • 18344389720 scopus 로고    scopus 로고
    • Causal relationship between the loss of RUNX3 expression and gastric cancer
    • Li Q-L, Ito K, Sakakura C, Fukamachi H, Inoue K-i, Chi X-Z et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 2002; 109: 113.
    • (2002) Cell , vol.109 , pp. 113
    • Li, Q.-L.1    Ito, K.2    Sakakura, C.3    Fukamachi, H.4    Inoue, K.-I.5    Chi, X.-Z.6
  • 24
    • 68949198148 scopus 로고    scopus 로고
    • MiR-107 and MiR- 185 can induce cell cycle arrest in human non small cell lung cancer cell lines
    • Takahashi Y, Forrest AR, Maeno E, Hashimoto T, Daub CO, Yasuda J. MiR-107 and MiR- 185 can induce cell cycle arrest in human non small cell lung cancer cell lines. PLoS One 2009; 4: e6677.
    • (2009) PLoS One , vol.4
    • Takahashi, Y.1    Forrest, A.R.2    Maeno, E.3    Hashimoto, T.4    Daub, C.O.5    Yasuda, J.6
  • 25
  • 26
    • 33745018595 scopus 로고    scopus 로고
    • The RUNX3 tumor suppressor upregulates bim in gastric epithelial cells undergoing transforming growth factorb-induced apoptosis
    • Yano T, Ito K, Fukamachi H, Chi X-Z, Wee H-J, Inoue K-i et al. The RUNX3 tumor suppressor upregulates bim in gastric epithelial cells undergoing transforming growth factorb-induced apoptosis. Mol Cell Biol 2006; 26: 4474-4488.
    • (2006) Mol Cell Biol , vol.26 , pp. 4474-4488
    • Yano, T.1    Ito, K.2    Fukamachi, H.3    Chi, X.-Z.4    Wee, H.-J.5    Inoue, K.-I.6
  • 27
    • 77952772783 scopus 로고    scopus 로고
    • RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a coactivator for p53
    • Yamada C, Ozaki T, Ando K, Suenaga Y, Inoue K-i, Ito Y et al. RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a coactivator for p53. J Biol Chem 2010; 285: 16693-16703.
    • (2010) J Biol Chem , vol.285 , pp. 16693-16703
    • Yamada, C.1    Ozaki, T.2    Ando, K.3    Suenaga, Y.4    Inoue, K.-I.5    Ito, Y.6
  • 28
    • 78651465898 scopus 로고    scopus 로고
    • MiR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells
    • Liu M, Lang N, Chen X, Tang Q, Liu S, Huang J et al. miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells. Cancer Lett 2011; 301: 151-160.
    • (2011) Cancer Lett , vol.301 , pp. 151-160
    • Liu, M.1    Lang, N.2    Chen, X.3    Tang, Q.4    Liu, S.5    Huang, J.6
  • 29
    • 40949087185 scopus 로고    scopus 로고
    • Identification of metastasisrelated microRNAs in hepatocellular carcinoma
    • Budhu A, Jia HL, Forgues M, Liu CG, Goldstein D, Lam A et al. Identification of metastasisrelated microRNAs in hepatocellular carcinoma. Hepatology 2008; 47: 897-907.
    • (2008) Hepatology , vol.47 , pp. 897-907
    • Budhu, A.1    Jia, H.L.2    Forgues, M.3    Liu, C.G.4    Goldstein, D.5    Lam, A.6
  • 30
    • 65349147075 scopus 로고    scopus 로고
    • Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries
    • Wyman SK, Parkin RK, Mitchell PS, Fritz BR, O'Briant K, Godwin AK et al. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. PLoS One 2009; 4: e5311.
    • (2009) PLoS One , vol.4
    • Wyman, S.K.1    Parkin, R.K.2    Mitchell, P.S.3    Fritz, B.R.4    O'Briant, K.5    Godwin, A.K.6
  • 31
    • 77956342464 scopus 로고    scopus 로고
    • MicroRNA- 185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers
    • Imam J, Buddavarapu K, Lee-Chang J, Ganapathy S, Camosy C, Chen Y et al. MicroRNA- 185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers. Oncogene 2010; 29: 4971-4979.
    • (2010) Oncogene , vol.29 , pp. 4971-4979
    • Imam, J.1    Buddavarapu, K.2    Lee-Chang, J.3    Ganapathy, S.4    Camosy, C.5    Chen, Y.6
  • 32
    • 84867758727 scopus 로고    scopus 로고
    • LRRC4 inhibits glioma cell growth and invasion through a miR-185-dependent pathway
    • Tang H, Wang Z, Liu X, Liu Q, Xu G, Li G et al. LRRC4 inhibits glioma cell growth and invasion through a miR-185-dependent pathway. Curr Cancer Drug Targets 2012; 12: 1032-1042.
    • (2012) Curr Cancer Drug Targets , vol.12 , pp. 1032-1042
    • Tang, H.1    Wang, Z.2    Liu, X.3    Liu, Q.4    Xu, G.5    Li, G.6
  • 33
    • 84875646958 scopus 로고    scopus 로고
    • MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor
    • Qu F, Cui X, Hong Y, Wang J, Li Y, Chen L et al. MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor. Mol Cell Biochem 2013; 377: 1-10.
    • (2013) Mol Cell Biochem , vol.377 , pp. 1-10
    • Qu, F.1    Cui, X.2    Hong, Y.3    Wang, J.4    Li, Y.5    Chen, L.6
  • 34
    • 84892652850 scopus 로고    scopus 로고
    • MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: A novel epigenetic therapy independent of decitabine
    • Xiang Y, Ma N, Wang D, Zhang Y, Zhou J, Wu G et al. MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine. Oncogene 2013; 33: 378-386.
    • (2013) Oncogene , vol.33 , pp. 378-386
    • Xiang, Y.1    Ma, N.2    Wang, D.3    Zhang, Y.4    Zhou, J.5    Wu, G.6
  • 35
    • 84883486821 scopus 로고    scopus 로고
    • GKN1-miR-185- DNMT1 axis suppresses gastric carcinogenesis through regulation of epigenetic alteration and cell cycle
    • Yoon JH, Choi YJ, Choi WS, Ashktorab H, Smoot D, Nam SW et al. GKN1-miR-185- DNMT1 axis suppresses gastric carcinogenesis through regulation of epigenetic alteration and cell cycle. Clin Cancer Res 2013; 19: 4599-4610.
    • (2013) Clin Cancer Res , vol.19 , pp. 4599-4610
    • Yoon, J.H.1    Choi, Y.J.2    Choi, W.S.3    Ashktorab, H.4    Smoot, D.5    Nam, S.W.6
  • 36
    • 84865213578 scopus 로고    scopus 로고
    • Functional importance of Dicer protein in the adaptive cellular response to hypoxia
    • Ho JD, Metcalf JL, Yan MS, Turgeon PJ, Wang JJ, Chalsev M et al. Functional importance of Dicer protein in the adaptive cellular response to hypoxia. J Biol Chem 2012; 287: 29003-29020.
    • (2012) J Biol Chem , vol.287 , pp. 29003-29020
    • Ho, J.D.1    Metcalf, J.L.2    Yan, M.S.3    Turgeon, P.J.4    Wang, J.J.5    Chalsev, M.6
  • 38
    • 77649221027 scopus 로고    scopus 로고
    • Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer
    • Wojcik SE, Rossi S, Shimizu M, Nicoloso MS, Cimmino A, Alder H et al. Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer. Carcinogenesis 2010; 31: 208-215.
    • (2010) Carcinogenesis , vol.31 , pp. 208-215
    • Wojcik, S.E.1    Rossi, S.2    Shimizu, M.3    Nicoloso, M.S.4    Cimmino, A.5    Alder, H.6
  • 39
    • 33751266107 scopus 로고    scopus 로고
    • RUNX3 inhibits the expression of vascular endothelial growth factor and reduces the angiogenesis, growth, and metastasis of human gastric cancer
    • Peng Z, Wei D, Wang L, Tang H, Zhang J, Le X et al. RUNX3 inhibits the expression of vascular endothelial growth factor and reduces the angiogenesis, growth, and metastasis of human gastric cancer. Clin Cancer Res 2006; 12: 6386-6394.
    • (2006) Clin Cancer Res , vol.12 , pp. 6386-6394
    • Peng, Z.1    Wei, D.2    Wang, L.3    Tang, H.4    Zhang, J.5    Le, X.6
  • 40
    • 70350231597 scopus 로고    scopus 로고
    • Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination
    • Chi X-Z, Kim J, Lee Y-H, Lee J-W, Lee K-S, Wee H et al. Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination. Cancer Res 2009; 69: 8111-8119.
    • (2009) Cancer Res , vol.69 , pp. 8111-8119
    • Chi, X.-Z.1    Kim, J.2    Lee, Y.-H.3    Lee, J.-W.4    Lee, K.-S.5    Wee, H.6
  • 41
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell-delivered S-TRAIL in human gliomas
    • Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell-delivered S-TRAIL in human gliomas. Cancer Res 2007; 67: 8994-9000.
    • (2007) Cancer Res , vol.67 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3    Krichevsky, A.M.4    Weissleder, R.5    Shah, K.6
  • 42
    • 82755176300 scopus 로고    scopus 로고
    • Anti-microRNA-222 (anti-miR-222) and-181B suppress growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal
    • Lu Y, Roy S, Nuovo G, Ramaswamy B, Miller T, Shapiro C et al. Anti-microRNA-222 (anti-miR-222) and-181B suppress growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal. J Biol Chem 2011; 286: 42292-42302.
    • (2011) J Biol Chem , vol.286 , pp. 42292-42302
    • Lu, Y.1    Roy, S.2    Nuovo, G.3    Ramaswamy, B.4    Miller, T.5    Shapiro, C.6
  • 43
    • 84871359778 scopus 로고    scopus 로고
    • Restoration of miR-200c to ovarian cancer reduces tumor burden and increases sensitivity to paclitaxel
    • Cittelly DM, Dimitrova I, Howe EN, Cochrane DR, Jean A, Spoelstra NS et al. Restoration of miR-200c to ovarian cancer reduces tumor burden and increases sensitivity to paclitaxel. Mol Cancer Therap 2012; 11: 2556-2565.
    • (2012) Mol Cancer Therap , vol.11 , pp. 2556-2565
    • Cittelly, D.M.1    Dimitrova, I.2    Howe, E.N.3    Cochrane, D.R.4    Jean, A.5    Spoelstra, N.S.6
  • 44
    • 67749106564 scopus 로고    scopus 로고
    • MiR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy
    • Lin Z, Murtaza I, Wang K, Jiao J, Gao J, Li P-F. miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy. Proc Natl Acad Sci USA 2009; 106: 12103-12108.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 12103-12108
    • Lin, Z.1    Murtaza, I.2    Wang, K.3    Jiao, J.4    Gao, J.5    Li, P.-F.6
  • 45
    • 78651232227 scopus 로고    scopus 로고
    • MiR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1
    • Wang J-X, Jiao J-Q, Li Q, Long B, Wang K, Liu J-P et al. miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nat Med 2010; 17: 71-78.
    • (2010) Nat Med , vol.17 , pp. 71-78
    • Wang, J.-X.1    Jiao, J.-Q.2    Li, Q.3    Long, B.4    Wang, K.5    Liu, J.-P.6


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