RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a Co-activator for p53

Journal of Biological Chemistry

Volumn 285, Issue 22, 2010, Pages 16693-16703

  Yamada, Chizu ^a,b   Ozaki, Toshinori ^a   Ando, Kiyohiro ^a   Suenaga, Yusuke ^a   Inoue, Ken Ichi ^c,d   Ito, Yoshiaki ^c,d   Okoshi, Rintaro ^a   Kageyama, Hajime ^a   Kimura, Hideki ^a   Miyazaki, Masaru ^b   Nakagawara, Akira ^a  

^a CHIBA CANCER CENTER   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ADRIAMYCIN; APOPTOSIS; ATAXIA-TELANGIECTASIA MUTATED; CELL NUCLEUS; COOH-TERMINAL; DNA DAMAGES; GASTRIC TUMORS; HUMAN LUNG; IMMUNOPRECIPITATIONS; IN-CELL; IN-VITRO; INHIBITORY ACTIVITY; MOLECULAR MECHANISM; PULLDOWN ASSAYS; SMALL INTERFERENCE RNA; TARGET GENE EXPRESSION; TRANSCRIPTIONAL ACTIVATIONS; TUMOR SUPPRESSION; TUMOR SUPPRESSORS;

CELL DEATH; CHEMICAL ACTIVATION; COORDINATION REACTIONS; DNA; GENE EXPRESSION; REFRIGERATORS; RNA; TUMORS;

PHOSPHORYLATION;

ATM PROTEIN; DOXORUBICIN; PROTEIN P53; SERINE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX3;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; LUNG ADENOCARCINOMA; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION;

ADENOCARCINOMA; APOPTOSIS; CELL LINE, TUMOR; CORE BINDING FACTOR ALPHA 3 SUBUNIT; DNA DAMAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MODELS, BIOLOGICAL; MUTATION; PHOSPHORYLATION; PROGNOSIS; SERINE; SUBCELLULAR FRACTIONS; TUMOR SUPPRESSOR PROTEIN P53;

ATAXIA TELANGIECTASIA;

EID: 77952772783     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.055525     Document Type: Article

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