Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2

Cell Death and Disease

Volumn 5, Issue 5, 2014, Pages

  Peng, X ^a   Mandal, P K ^b,d   Kaminskyy, V O ^a   Lindqvist, A ^a   Conrad, M ^c   Arner E S J ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Glucose; Mouse embryonic fibroblasts (MEFs); Reactive oxygen species (ROS); Selenocysteine; Thioredoxin reductase 1 (TrxR1)

Indexed keywords

CATALASE; GLUCOSE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; SELENOCYSTEINE; THIOREDOXIN REDUCTASE 1;

ANIMAL CELL; ARTICLE; CELL CONTACT; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CELL PROTECTION; CELL VIABILITY ASSAY; COLONY FORMATION; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY ASSAY; EMBRYO; ENZYME ACTIVITY; FIBROBLAST; GENE INACTIVATION; GLUCOSE METABOLISM; HYPERGLYCEMIA; IN VITRO STUDY; METABOLIC REGULATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONCENTRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; ANTIOXIDANTS; CELL DEATH; CELL LINE; CELL PROLIFERATION; FIBROBLASTS; GLUCOSE; GLUTATHIONE; HYDROGEN PEROXIDE; MICE; MICE, KNOCKOUT; MUTATION; OXIDATIVE STRESS; RECOMBINANT PROTEINS; SELENOCYSTEINE; SIGNAL TRANSDUCTION; THIOREDOXIN REDUCTASE 1; TIME FACTORS; TRANSFECTION;

EID: 84901049603     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.209     Document Type: Article

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