-
1
-
-
79957606295
-
The life cycle of hepatitis B virus and antiviral targets
-
J. Lucifora, and F. Zoulim The life cycle of hepatitis B virus and antiviral targets Future Virol 6 2011 599 614
-
(2011)
Future Virol
, vol.6
, pp. 599-614
-
-
Lucifora, J.1
Zoulim, F.2
-
2
-
-
84878850500
-
The molecular virology of hepatitis B virus
-
D. Glebe, and C.M. Bremer The molecular virology of hepatitis B virus Semin Liver Dis 33 2013 103 112
-
(2013)
Semin Liver Dis
, vol.33
, pp. 103-112
-
-
Glebe, D.1
Bremer, C.M.2
-
3
-
-
84880636445
-
The natural course of chronic hepatitis B virus infection and its management
-
S.J. Hadziyannis, D. Vassilopoulos, and E. Hadziyannis The natural course of chronic hepatitis B virus infection and its management Adv Pharmacol 67 2013 247 291
-
(2013)
Adv Pharmacol
, vol.67
, pp. 247-291
-
-
Hadziyannis, S.J.1
Vassilopoulos, D.2
Hadziyannis, E.3
-
4
-
-
43049117085
-
Hepatitis B viruses: Reverse transcription a different way
-
M. Nassal Hepatitis B viruses: reverse transcription a different way Virus Res 134 2008 235 249
-
(2008)
Virus Res
, vol.134
, pp. 235-249
-
-
Nassal, M.1
-
5
-
-
0024784519
-
Identification of four conserved motifs among the RNA-dependent polymerase encoding elements
-
O. Poch, I. Sauvaget, M. Delarue, and N. Tordo Identification of four conserved motifs among the RNA-dependent polymerase encoding elements EMBO J 8 1989 3867 3874 (Pubitemid 20016069)
-
(1989)
EMBO Journal
, vol.8
, Issue.12
, pp. 3867-3874
-
-
Poch, O.1
Sauvaget, I.2
Delarue, M.3
Tordo, N.4
-
6
-
-
17744375593
-
Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region
-
DOI 10.1053/jhep.2001.22166
-
L.J. Stuyver, S.A. Locarnini, A. Lok, D.D. Richman, W.F. Carman, J.L. Dienstag, and R.F. Schinazi Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region Hepatology 33 2001 751 757 (Pubitemid 32185239)
-
(2001)
Hepatology
, vol.33
, Issue.3
, pp. 751-757
-
-
Stuyver, L.J.1
Locarnini, S.A.2
Lok, A.3
Richman, D.D.4
Carman, W.F.5
Dienstag, J.L.6
Schinazi, R.F.7
Bartholomeusz, A.8
Di Bisceglie, A.9
De Man, R.A.10
Dusheiko, G.11
Furman, P.A.12
La Colla, P.13
Lai, C.-L.14
Lau, J.Y.N.15
Manns, M.P.16
Niesters, H.G.M.17
Omata, M.18
Ono-Nita, S.K.19
Otto, M.J.20
Pillay, D.21
Poynard, T.22
Sommadossi, J.-P.23
Shouval, D.24
Soriano, V.25
Thomas, H.26
Will, H.27
Zoulim, F.28
more..
-
7
-
-
84874705088
-
Protein-primed terminal transferase activity of hepatitis B virus polymerase
-
Erratum in: J Virol 2013, 87:12505
-
S.A. Jones, and J. Hu Protein-primed terminal transferase activity of hepatitis B virus polymerase J Virol 87 2013 2563 2576 Erratum in: J Virol 2013, 87:12505
-
(2013)
J Virol
, vol.87
, pp. 2563-2576
-
-
Jones, S.A.1
Hu, J.2
-
8
-
-
0025061039
-
Mutational analysis of the hepatitis B virus P gene product: Domain structure and RNase H activity
-
G. Radziwill, W. Tucker, and H. Schaller Mutational analysis of the hepatitis B virus P gene product: domain structure and RNase H activity J Virol 64 1990 613 620 (Pubitemid 20032673)
-
(1990)
Journal of Virology
, vol.64
, Issue.2
, pp. 613-620
-
-
Radziwill, G.1
Tucker, W.2
Schaller, H.3
-
9
-
-
84861321768
-
In vitro epsilon RNA-dependent protein priming activity of human hepatitis B virus polymerase
-
Erratum in: J Virol 2013, 87:12504
-
S.A. Jones, R. Boregowda, T.E. Spratt, and J. Hu In vitro epsilon RNA-dependent protein priming activity of human hepatitis B virus polymerase J Virol 86 2012 5134 5150 Erratum in: J Virol 2013, 87:12504
-
(2012)
J Virol
, vol.86
, pp. 5134-5150
-
-
Jones, S.A.1
Boregowda, R.2
Spratt, T.E.3
Hu, J.4
-
10
-
-
0031777692
-
The duck hepatitis B virus polymerase is activated by its RNA packaging signal, ε
-
J.E. Tavis, B. Massey, and Y. Gong The duck hepatitis B virus polymerase is activated by its RNA packaging signal, J Virol 72 1998 5789 5796 (Pubitemid 28283364)
-
(1998)
Journal of Virology
, vol.72
, Issue.7
, pp. 5789-5796
-
-
Tavis, J.E.1
Massey, B.2
Gong, Y.3
-
11
-
-
84896739556
-
Large-scale production and structural and biophysical characterizations of the human hepatitis B virus polymerase
-
J. Vörös, A. Urbanek, G.J.P. Rautureau, M. O'Connor, H.C. Fisher, A.E. Ashcroft, and N. Ferguson Large-scale production and structural and biophysical characterizations of the human hepatitis B virus polymerase J Virol 88 2014 2584 2599
-
(2014)
J Virol
, vol.88
, pp. 2584-2599
-
-
Vörös, J.1
Urbanek, A.2
Rautureau, G.J.P.3
O'Connor, M.4
Fisher, H.C.5
Ashcroft, A.E.6
Ferguson, N.7
-
12
-
-
35448984203
-
The topology of hepatitis B virus pregenomic RNA promotes its replication
-
DOI 10.1128/JVI.01414-07
-
T.M. Abraham, and D.D. Loeb The topology of hepatitis B virus pregenomic RNA promotes its replication J Virol 81 2007 11577 11584 (Pubitemid 47623789)
-
(2007)
Journal of Virology
, vol.81
, Issue.21
, pp. 11577-11584
-
-
Abraham, T.M.1
Loeb, D.D.2
-
13
-
-
34247107229
-
Inhibition of hepatitis B virus polymerase by entecavir
-
DOI 10.1128/JVI.02395-06
-
D.R. Langley, A.W. Walsh, C.J. Baldick, B.J. Eggers, R.E. Rose, S.M. Levine, A.J. Kapur, R.J. Colonno, and D.J. Tenney Inhibition of hepatitis B virus polymerase by entecavir J Virol 81 2007 3992 4001 (Pubitemid 46586894)
-
(2007)
Journal of Virology
, vol.81
, Issue.8
, pp. 3992-4001
-
-
Langley, D.R.1
Walsh, A.W.2
Baldick, C.J.3
Eggers, B.J.4
Rose, R.E.5
Levine, S.M.6
Kapur, A.J.7
Colonno, R.J.8
Tenney, D.J.9
-
14
-
-
57749104132
-
Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase
-
E.P. Tchesnokov, A. Obikhod, R.F. Schinazi, and M. Götte Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase J Biol Chem 283 2008 34218 34228
-
(2008)
J Biol Chem
, vol.283
, pp. 34218-34228
-
-
Tchesnokov, E.P.1
Obikhod, A.2
Schinazi, R.F.3
Götte, M.4
-
15
-
-
84882363291
-
Noncompetitive inhibition of hepatitis B virus reverse transcriptase protein priming and DNA synthesis by the nucleoside analog clevudine
-
Erratum in: Antimicrob Agents Chemother 2013, 57:5788
-
S.A. Jones, E. Murakami, W. Delaney, P. Furman, and J. Hu Noncompetitive inhibition of hepatitis B virus reverse transcriptase protein priming and DNA synthesis by the nucleoside analog clevudine Antimicrob Agents Chemother 57 2013 4181 4189 Erratum in: Antimicrob Agents Chemother 2013, 57:5788
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 4181-4189
-
-
Jones, S.A.1
Murakami, E.2
Delaney, W.3
Furman, P.4
Hu, J.5
-
16
-
-
0024316283
-
Mutation rate of the hepadnavirus genome
-
DOI 10.1016/0042-6822(89)90455-8
-
R. Gironés, and R.H. Miller Mutation rate of the hepadnavirus genome Virology 170 1989 595 597 (Pubitemid 19162574)
-
(1989)
Virology
, vol.170
, Issue.2
, pp. 595-597
-
-
Girones, R.1
Miller, R.H.2
-
17
-
-
10744225554
-
Long-term safety of lamivudine treatment in patients with chronic hepatitis b
-
DOI 10.1053/j.gastro.2003.09.033
-
A.S. Lok, C.L. Lai, N. Leung, G.B. Yao, Z.Y. Cui, E.R. Schiff, J.L. Dienstag, E.J. Heathcote, N.R. Little, and D.A. Griffiths et al. Long-term safety of lamivudine treatment in patients with chronic hepatitis B Gastroenterology 125 2003 1714 1722 (Pubitemid 37500436)
-
(2003)
Gastroenterology
, vol.125
, Issue.6
, pp. 1714-1722
-
-
Lok, A.S.F.1
Lai, C.-L.2
Leung, N.3
Yao, G.-B.4
Cui, Z.-Y.5
Schiff, E.R.6
Dienstag, J.L.7
Heathcote, E.J.8
Little, N.R.9
Griffiths, D.A.10
Gardner, S.D.11
Castiglia, M.12
-
18
-
-
33845671388
-
Long-term Therapy With Adefovir Dipivoxil for HBeAg-Negative Chronic Hepatitis B for up to 5 Years
-
DOI 10.1053/j.gastro.2006.09.020, PII S0016508506020804
-
S.J. Hadziyannis, N.C. Tassopoulos, E.J. Heathcote, T.T. Chang, G. Kitis, M. Rizzetto, P. Marcellin, S.G. Lim, Z. Goodman, and J. Ma et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years Gastroenterology 131 2006 1743 1751 (Pubitemid 44958517)
-
(2006)
Gastroenterology
, vol.131
, Issue.6
, pp. 1743-1751
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
Chang, T.4
Kitis, G.5
Rizzetto, M.6
Marcellin, P.7
Lim, S.G.8
Goodman, Z.9
Ma, J.10
Brosgart, C.L.11
Borroto-Esoda, K.12
Arterburn, S.13
Chuck, S.L.14
-
19
-
-
84860390069
-
Significance of HBV DNA levels at 12 weeks of telbivudine treatment and the 3 years treatment outcome
-
W.K. Seto, C.L. Lai, J. Fung, D.K. Wong, J.C. Yuen, I.F. Hung, and M.F. Yuen Significance of HBV DNA levels at 12 weeks of telbivudine treatment and the 3 years treatment outcome J Hepatol 55 2011 522 528
-
(2011)
J Hepatol
, vol.55
, pp. 522-528
-
-
Seto, W.K.1
Lai, C.L.2
Fung, J.3
Wong, D.K.4
Yuen, J.C.5
Hung, I.F.6
Yuen, M.F.7
-
20
-
-
75449107726
-
Entecavir treatment for up to 5 years in patients with hepatitis B e antigen-positive chronic hepatitis B
-
T.T. Chang, C.L. Lai, S. Kew Yoon, S.S. Lee, H.S. Coelho, F.J. Carrilho, F. Poordad, W. Halota, Y. Horsmans, and N. Tsai et al. Entecavir treatment for up to 5 years in patients with hepatitis B e antigen-positive chronic hepatitis B Hepatology 51 2010 422 430
-
(2010)
Hepatology
, vol.51
, pp. 422-430
-
-
Chang, T.T.1
Lai, C.L.2
Kew Yoon, S.3
Lee, S.S.4
Coelho, H.S.5
Carrilho, F.J.6
Poordad, F.7
Halota, W.8
Horsmans, Y.9
Tsai, N.10
-
21
-
-
84873726484
-
Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: A 5-year open-label follow-up study
-
P. Marcellin, E. Gane, M. Buti, N. Afdhal, W. Sievert, I.M. Jacobson, M.K. Washington, G. Germanidis, J.F. Flaherty, and R.A. Schall et al. Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study Lancet 381 2013 468 475
-
(2013)
Lancet
, vol.381
, pp. 468-475
-
-
Marcellin, P.1
Gane, E.2
Buti, M.3
Afdhal, N.4
Sievert, W.5
Jacobson, I.M.6
Washington, M.K.7
Germanidis, G.8
Flaherty, J.F.9
Schall, R.A.10
-
22
-
-
84893652874
-
No detectable resistance to tenofovir disoproxil fumarate after 6 years of therapy in patients with chronic hepatitis B
-
K.M. Kitrinos, A. Corsa, Y. Liu, J. Flaherty, A. Snow-Lampart, P. Marcellin, K. Borroto-Esoda, and M.D. Miller No detectable resistance to tenofovir disoproxil fumarate after 6 years of therapy in patients with chronic hepatitis B Hepatology 59 2014 434 442
-
(2014)
Hepatology
, vol.59
, pp. 434-442
-
-
Kitrinos, K.M.1
Corsa, A.2
Liu, Y.3
Flaherty, J.4
Snow-Lampart, A.5
Marcellin, P.6
Borroto-Esoda, K.7
Miller, M.D.8
-
23
-
-
34447255407
-
The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro
-
DOI 10.1128/AAC.01499-06
-
N. Warner, S. Locarnini, M. Kuiper, A. Bartholomeusz, A. Ayres, L. Yuen, and T. Shaw The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro Antimicrob Agents Chemother 51 2007 2285 2292 (Pubitemid 47047302)
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, Issue.7
, pp. 2285-2292
-
-
Warner, N.1
Locarnini, S.2
Kuiper, M.3
Bartholomeusz, A.4
Ayres, A.5
Yuen, L.6
Shaw, T.7
-
24
-
-
78650243279
-
Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery
-
S.Y. Rhee, S. Margeridon-Thermet, M.H. Nguyen, T.F. Liu, R.M. Kagan, B. Beggel, J. Verheyen, R. Kaiser, and R.W. Shafer Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery Antiviral Res 88 2010 269 275
-
(2010)
Antiviral Res
, vol.88
, pp. 269-275
-
-
Rhee, S.Y.1
Margeridon-Thermet, S.2
Nguyen, M.H.3
Liu, T.F.4
Kagan, R.M.5
Beggel, B.6
Verheyen, J.7
Kaiser, R.8
Shafer, R.W.9
-
25
-
-
84880814339
-
Association of preexisting drug-resistance mutations and treatment failure in hepatitis B patients
-
J. Ma, Y. Zhang, X. Chen, Y. Jin, D. Chen, Y. Wu, J. Cui, H. Wang, J. Liu, N. Li, and F. Gao Association of preexisting drug-resistance mutations and treatment failure in hepatitis B patients PLoS ONE 8 2013 e67606
-
(2013)
PLoS ONE
, vol.8
, pp. 67606
-
-
Ma, J.1
Zhang, Y.2
Chen, X.3
Jin, Y.4
Chen, D.5
Wu, Y.6
Cui, J.7
Wang, H.8
Liu, J.9
Li, N.10
Gao, F.11
-
26
-
-
34547792213
-
A novel mutation pattern emerging during lamivudine treatment shows cross-resistance to adefovir dipivoxil treatment
-
E. Karatayli, S. Karayalçin, H. Karaaslan, H. Kayhan, A.R. Türkyilmaz, F. Sahin, C. Yurdaydin, and A.M. Bozdayi A novel mutation pattern emerging during lamivudine treatment shows cross-resistance to adefovir dipivoxil treatment Antivir Ther 12 2007 761 768 (Pubitemid 47235490)
-
(2007)
Antiviral Therapy
, vol.12
, Issue.5
, pp. 761-768
-
-
Karatayli, E.1
Karayalcin, S.2
Karaaslan, H.3
Kayhan, H.4
Turkyilmaz, A.R.5
Sahin, F.6
Yurdaydin, C.7
Bozdayi, A.M.8
-
27
-
-
33750588091
-
Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif
-
DOI 10.1128/AAC.00239-06
-
H. Yatsuji, C. Noguchi, N. Hiraga, N. Mori, M. Tsuge, M. Imamura, S. Takahashi, E. Iwao, Y. Fujimoto, and H. Ochi et al. Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif Antimicrob Agents Chemother 50 2006 3867 3874 (Pubitemid 44684905)
-
(2006)
Antimicrobial Agents and Chemotherapy
, vol.50
, Issue.11
, pp. 3867-3874
-
-
Yatsuji, H.1
Noguchi, C.2
Hiraga, N.3
Mori, N.4
Tsuge, M.5
Imamura, M.6
Takahashi, S.7
Iwao, E.8
Fujimoto, Y.9
Ochi, H.10
Abe, H.11
Maekawa, T.12
Tateno, C.13
Yoshizato, K.14
Suzuki, F.15
Kumada, H.16
Chayama, K.17
-
28
-
-
0029815110
-
Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine
-
DOI 10.1053/jhep.1996.v24.pm0008781347
-
R. Ling, D. Mutimer, M. Ahmed, E.H. Boxall, E. Elias, G.M. Dusheiko, and T.J. Harrison Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine Hepatology 24 1996 711 713 (Pubitemid 26296020)
-
(1996)
Hepatology
, vol.24
, Issue.3
, pp. 711-713
-
-
Ling, R.1
Mutimer, D.2
Ahmed, M.3
Boxall, E.H.4
Elias, E.5
Dusheiko, G.M.6
Harrison, T.J.7
-
29
-
-
0031780935
-
Identification and characterization of mutations in hepatitis B virus resistant to lamivudine
-
DOI 10.1002/hep.510270628
-
M.I. Allen, M. Deslauriers, C.W. Andrews, G.A. Tipples, K.-A. Walters, D.L.J. Tyrrell, N. Brown, for the Lamivudine Clinical Investigation Group, and L.D. Condreay Identification and characterization of mutations in hepatitis B virus resistant to lamivudine Hepatology 27 1998 1670 1677 (Pubitemid 28264693)
-
(1998)
Hepatology
, vol.27
, Issue.6
, pp. 1670-1677
-
-
Allen, M.I.1
Deslauriers, M.2
Webster Andrews, C.3
Tipples, G.A.4
Walters, K.-A.5
Tyrrell, D.L.J.6
Brown, N.7
Condreay, L.D.8
-
30
-
-
0036208099
-
Kinetic analysis of wild-type and YMDD mutant hepatitis B virus polymerases and effects of deoxyribonucleotide concentrations on polymerase activity
-
DOI 10.1128/AAC.46.4.1005-1013.2002
-
R.K. Gaillard, J. Barnard, V. Lopez, P. Hodges, E. Bourne, L. Johnson, M.I. Allen, P. Condreay, W.H. Miller, and L.D. Condreay Kinetic analysis of wild-type and YMDD mutant hepatitis B virus polymerases and effects of deoxyribonucleotide concentrations on polymerase activity Antimicrob Agents Chemother 46 2002 1005 1013 (Pubitemid 34260343)
-
(2002)
Antimicrobial Agents and Chemotherapy
, vol.46
, Issue.4
, pp. 1005-1013
-
-
Gaillard, R.K.1
Barnard, J.2
Lopez, V.3
Hodges, P.4
Bourne, E.5
Johnson, L.6
Allen, M.I.7
Condreay, P.8
Miller, W.H.9
Condreay, L.D.10
-
31
-
-
3543081472
-
Basal core promoter and precore mutations in the hepatitis B virus genome enhance replication efficacy of lamivudine-resistant mutants
-
DOI 10.1128/JVI.78.16.8524-8535.2004
-
F. Tacke, C. Gehrke, T. Luedde, A. Heim, M.P. Manns, and C. Trautwein Basal core promoter and precore mutations in the hepatitis B virus genome enhance replication efficacy of lamivudine-resistant mutants J Virol 78 2004 8524 8535 (Pubitemid 39025118)
-
(2004)
Journal of Virology
, vol.78
, Issue.16
, pp. 8524-8535
-
-
Tacke, F.1
Gehrke, C.2
Luedde, T.3
Heim, A.4
Manns, M.P.5
Trautwein, C.6
-
32
-
-
84896070205
-
RtM204Q may serve as a novel lamivudine-resistance-associated mutation of hepatitis B virus
-
Y. Liu, Z. Xu, Y. Wang, X. Li, L. Liu, L. Chen, S. Xin, and D. Xu rtM204Q may serve as a novel lamivudine-resistance-associated mutation of hepatitis B virus PLoS ONE 9 2014 e89015
-
(2014)
PLoS ONE
, vol.9
, pp. 89015
-
-
Liu, Y.1
Xu, Z.2
Wang, Y.3
Li, X.4
Liu, L.5
Chen, L.6
Xin, S.7
Xu, D.8
-
33
-
-
18544383966
-
Prevalence, incidence, and clinical relevance of the reverse transcriptase V207I mutation outside the YMDD motif of the hepatitis B virus polymerase during lamivudine therapy
-
DOI 10.1128/JCM.43.5.2503-2505.2005
-
B. Zöllner, M. Sterneck, K. Wursthorn, J. Petersen, M. Schröter, R. Laufs, and H.H. Feucht Prevalence, incidence, and clinical relevance of the reverse transcriptase V207I mutation outside the YMDD motif of the hepatitis B virus polymerase during lamivudine therapy J Clin Microbiol 43 2005 2503 2505 (Pubitemid 40656280)
-
(2005)
Journal of Clinical Microbiology
, vol.43
, Issue.5
, pp. 2503-2505
-
-
Zollner, B.1
Sterneck, M.2
Wursthorn, K.3
Petersen, J.4
Schroter, M.5
Laufs, R.6
Feucht, H.-H.7
-
34
-
-
84860304712
-
Long-term monitoring drug resistance by ultra-deep pyrosequencing in a chronic hepatitis B virus (HBV)-infected patient exposed to several unsuccessful therapy schemes
-
M. Sede, D. Ojeda, L. Cassino, G. Westergaard, M. Vazquez, S. Benetti, F. Fay, H. Tanno, and J. Quarleri Long-term monitoring drug resistance by ultra-deep pyrosequencing in a chronic hepatitis B virus (HBV)-infected patient exposed to several unsuccessful therapy schemes Antiviral Res 94 2012 184 187
-
(2012)
Antiviral Res
, vol.94
, pp. 184-187
-
-
Sede, M.1
Ojeda, D.2
Cassino, L.3
Westergaard, G.4
Vazquez, M.5
Benetti, S.6
Fay, F.7
Tanno, H.8
Quarleri, J.9
-
35
-
-
84859207020
-
Identification of hepatitis B virus rtS117F substitution as a compensatory mutation for rtM204I during lamivudine therapy
-
C.L. Lin, R.N. Chien, C.C. Hu, M.W. Lai, and C.T. Yeh Identification of hepatitis B virus rtS117F substitution as a compensatory mutation for rtM204I during lamivudine therapy J Antimicrob Chemother 67 2012 39 48
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 39-48
-
-
Lin, C.L.1
Chien, R.N.2
Hu, C.C.3
Lai, M.W.4
Yeh, C.T.5
-
36
-
-
21444445694
-
Emergence of a novel mutation in the FLLA region of hepatitis B virus during lamivudine therapy
-
DOI 10.1128/AAC.49.7.2618-2624.2005
-
S.B. Pai, A.M. Bozdayi, R.B. Pai, T. Beker, M. Sarioglu, A.R. Turkyilmaz, J. Grier, C. Yurdaydin, and R.F. Schinazi Emergence of a novel mutation in the FLLA region of hepatitis B virus during lamivudine therapy Antimicrob Agents Chemother 49 2005 2618 2624 (Pubitemid 40917570)
-
(2005)
Antimicrobial Agents and Chemotherapy
, vol.49
, Issue.7
, pp. 2618-2624
-
-
Pai, S.B.1
Bozdayi, A.M.2
Pai, R.B.3
Beker, T.4
Sarioglu, M.5
Turkyilmaz, A.R.6
Grier, J.7
Yurdaydin, C.8
Schinazi, R.F.9
-
37
-
-
33845604017
-
Unusual selection of rtA181V HBV mutants cross-resistant to adefovir following prolonged lamivudine monotherapy: Report of two cases
-
R. Gerolami, M. Bourliere, P. Colson, P. Halfon, P. Borentain, M. Henry, D. Botta, V. Thibault, H. Khiri, and C. Tamalet Unusual selection of rtA181V HBV mutants cross-resistant to adefovir following prolonged lamivudine monotherapy: report of two cases Antivir Ther 11 2006 1103 1106 (Pubitemid 44955187)
-
(2006)
Antiviral Therapy
, vol.11
, Issue.8
, pp. 1103-1106
-
-
Gerolami, R.1
Bourliere, M.2
Colson, P.3
Halfon, P.4
Borentain, P.5
Henry, M.6
Botta, D.7
Thibault, V.8
Khiri, H.9
Tamalet, C.10
-
38
-
-
58849151844
-
Molecular analysis of an HBsAg-negative hepatitis B virus mutant selected in a tenofovir-treated HIV-hepatitis B virus co-infected patient
-
S. Amini-Bavil-Olyaee, J. Sheldon, T. Lutz, C. Trautwein, and F. Tacke Molecular analysis of an HBsAg-negative hepatitis B virus mutant selected in a tenofovir-treated HIV-hepatitis B virus co-infected patient AIDS 23 2009 268 272
-
(2009)
AIDS
, vol.23
, pp. 268-272
-
-
Amini-Bavil-Olyaee, S.1
Sheldon, J.2
Lutz, T.3
Trautwein, C.4
Tacke, F.5
-
39
-
-
33847683844
-
Two-year assessment of entecavir resistance in lamivudine-refractory hepatitis B virus patients reveals different clinical outcomes depending on the resistance substitutions present
-
DOI 10.1128/AAC.00833-06
-
D.J. Tenney, R.E. Rose, C.J. Baldick, S.M. Levine, K.A. Pokornowski, A.W. Walsh, J. Fang, C.F. Yu, S. Zhang, and C.E. Mazzucco et al. Two-year assessment of entecavir resistance in lamivudine-refractory hepatitis B virus patients reveals different clinical outcomes depending on the resistance substitutions present Antimicrob Agents Chemother 51 2007 902 911 (Pubitemid 46355274)
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, Issue.3
, pp. 902-911
-
-
Tenney, D.J.1
Rose, R.E.2
Baldick, C.J.3
Levine, S.M.4
Pokornowski, K.A.5
Walsh, A.W.6
Fang, J.7
Yu, C.-F.8
Zhang, S.9
Mazzucco, C.E.10
Eggers, B.11
Hsu, M.12
Plym, M.J.13
Poundstone, P.14
Yang, J.15
Colonno, R.J.16
-
40
-
-
0038045176
-
YSDD: A novel mutation in HBV DNA polymerase confers clinical resistance to lamivudine
-
DOI 10.1046/j.1365-2893.2003.00435.x
-
A.M. Bozdayi, O. Uzunalimoǧlu, A.R. Türkyilmaz, N. Aslan, O. Sezgin, T. Sahin, G. Bozdayi, K. Cinar, S.B. Pai, and R. Pai et al. YSDD: a novel mutation in HBV DNA polymerase confers clinical resistance to lamivudine J Viral Hepat 10 2003 256 265 (Pubitemid 36801911)
-
(2003)
Journal of Viral Hepatitis
, vol.10
, Issue.4
, pp. 256-265
-
-
Bozdayi, A.M.1
Uzunalimoglu, O.2
Turkyilmaz, A.R.3
Aslan, N.4
Sezgin, O.5
Sahin, T.6
Bozdayi, G.7
Cinar, K.8
Pai, S.B.9
Pai, R.10
Bozkaya, H.11
Karayalcin, S.12
Yurdaydin, C.13
Schinazi, R.F.14
-
41
-
-
10244244926
-
Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment
-
DOI 10.1097/00002030-200411190-00014
-
O. Schildgen, C.K. Schewe, M. Vogel, M. Däumer, R. Kaiser, L. Weitner, B. Matz, and J.K. Rockstroh Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment AIDS 18 2004 2325 2327 (Pubitemid 39620226)
-
(2004)
AIDS
, vol.18
, Issue.17
, pp. 2325-2327
-
-
Schildgen, O.1
Schewe, C.K.2
Vogel, M.3
Daumer, M.4
Kaiser, R.5
Weitner, L.6
Matz, B.7
Rockstroh, J.K.8
-
42
-
-
84862779361
-
The rtL229 substitutions in the reverse transcriptase region of hepatitis B virus (HBV) polymerase are potentially associated with lamivudine resistance as a compensatory mutation
-
D. Ji, Y. Liu, L. Li, Z. Xu, L.L. Si, J.Z. Dai, X. Li, L. Wang, Z. Yao, and S.J. Xin et al. The rtL229 substitutions in the reverse transcriptase region of hepatitis B virus (HBV) polymerase are potentially associated with lamivudine resistance as a compensatory mutation J Clin Virol 54 2012 66 72
-
(2012)
J Clin Virol
, vol.54
, pp. 66-72
-
-
Ji, D.1
Liu, Y.2
Li, L.3
Xu, Z.4
Si, L.L.5
Dai, J.Z.6
Li, X.7
Wang, L.8
Yao, Z.9
Xin, S.J.10
-
43
-
-
84887476057
-
Substitution rtq267h of hepatitis B virus increases the weight of replication and lamivudine resistance
-
B. Qin, B. Zhang, X. Zhang, T. He, W. Xu, L. Fu, and C. Tu Substitution rtq267h of hepatitis B virus increases the weight of replication and lamivudine resistance Hepat Mon 13 2013 e12160
-
(2013)
Hepat Mon
, vol.13
, pp. 12160
-
-
Qin, B.1
Zhang, B.2
Zhang, X.3
He, T.4
Xu, W.5
Fu, L.6
Tu, C.7
-
44
-
-
62749177499
-
Hepatitis B virus with the rtL80V/I mutation is associated with a poor response to adefovir dipivoxil therapy
-
Y.S. Lee, Y.H. Chung, J.A. Kim, S.E. Kim, J.W. Shin, K.M. Kim, Y.S. Lim, N.H. Park, H.C. Lee, Y.S. Lee, and D.J. Suh Hepatitis B virus with the rtL80V/I mutation is associated with a poor response to adefovir dipivoxil therapy Liver Int 29 2009 552 556
-
(2009)
Liver Int
, vol.29
, pp. 552-556
-
-
Lee, Y.S.1
Chung, Y.H.2
Kim, J.A.3
Kim, S.E.4
Shin, J.W.5
Kim, K.M.6
Lim, Y.S.7
Park, N.H.8
Lee, H.C.9
Lee, Y.S.10
Suh, D.J.11
-
45
-
-
41249103028
-
Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure
-
S. Villet, C. Pichoud, G. Billioud, L. Barraud, S. Durantel, C. Trépo, and F. Zoulim Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure J Hepatol 48 2008 747 755
-
(2008)
J Hepatol
, vol.48
, pp. 747-755
-
-
Villet, S.1
Pichoud, C.2
Billioud, G.3
Barraud, L.4
Durantel, S.5
Trépo, C.6
Zoulim, F.7
-
46
-
-
27744510332
-
Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation
-
DOI 10.1016/j.jhep.2005.05.037, PII S0168827805004319
-
S.K. Fung, P. Andreone, S.H. Han, K.R. Reddy, A. Regev, E.B. Keeffe, M. Hussain, C. Cursaro, P. Richtmyer, J.A. Marrero, and A.S.F. Lok Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation J Hepatol 43 2005 937 943 (Pubitemid 41627977)
-
(2005)
Journal of Hepatology
, vol.43
, Issue.6
, pp. 937-943
-
-
Fung, S.K.1
Andreone, P.2
Han, S.H.3
Rajender Reddy, K.4
Regev, A.5
Keeffe, E.B.6
Hussain, M.7
Cursaro, C.8
Richtmyer, P.9
Marrero, J.A.10
Lok, A.S.F.11
-
47
-
-
34548349001
-
Pooled analysis of amino acid changes in the HBV polymerase in patients from four major adefovir dipivoxil clinical trials
-
DOI 10.1016/j.jhep.2007.06.011, PII S0168827807003947
-
K. Borroto-Esoda, M.D. Miller, and S. Arterburn Pooled analysis of amino acid changes in the HBV polymerase in patients from four major adefovir dipivoxil clinical trials J Hepatol 47 2007 492 498 (Pubitemid 47334760)
-
(2007)
Journal of Hepatology
, vol.47
, Issue.4
, pp. 492-498
-
-
Borroto-Esoda, K.1
Miller, M.D.2
Arterburn, S.3
-
48
-
-
77749317031
-
RtE218G, a novel hepatitis B virus mutation with resistance to adefovir dipivoxil in patients with chronic hepatitis B
-
L.J. Liu, J.H. Wang, S.C. Du, J.H. Tian, R.F. Yang, and L. Wei rtE218G, a novel hepatitis B virus mutation with resistance to adefovir dipivoxil in patients with chronic hepatitis B J Viral Hepat 17 Suppl 1 2010 66 72
-
(2010)
J Viral Hepat
, vol.17
, Issue.SUPPL. 1
, pp. 66-72
-
-
Liu, L.J.1
Wang, J.H.2
Du, S.C.3
Tian, J.H.4
Yang, R.F.5
Wei, L.6
-
49
-
-
0041853784
-
Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase
-
DOI 10.1016/S0016-5085(03)00939-9
-
P. Angus, R. Vaughan, S. Xiong, H. Yang, W. Delaney, C. Gibbs, C. Brosgart, D. Colledge, R. Edwards, and A. Ayres et al. Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase Gastroenterology 125 2003 292 297 (Pubitemid 36929407)
-
(2003)
Gastroenterology
, vol.125
, Issue.2
, pp. 292-297
-
-
Angus, P.1
Vaughan, R.2
Xiong, S.3
Yang, H.4
Delaney, W.5
Gibbs, C.6
Brosgart, C.7
Colledge, D.8
Edwards, R.9
Ayres, A.10
Bartholomeusz, A.11
Locarnini, S.12
-
50
-
-
21244455293
-
Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B
-
DOI 10.1056/NEJMoa042957
-
S.J. Hadziyannis, N.C. Tassopoulos, E.J. Heathcote, T.T. Chang, G. Kitis, M. Rizzetto, P. Marcellin, S.G. Lim, Z. Goodman, and J. Ma et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B N Engl J Med 352 2005 2673 2681 (Pubitemid 41007822)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.26
, pp. 2673-2681
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Jenny Heathcote, E.3
Chang, T.-T.4
Kitis, G.5
Rizzetto, M.6
Marcellin, P.7
Seng, G.L.8
Goodman, Z.9
Ma, J.10
Arterburn, S.11
Xiong, S.12
Currie, G.13
Brosgart, C.L.14
-
51
-
-
84882856674
-
Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen
-
V. Cento, F. Van Hemert, M. Neumann-Fraune, C. Mirabelli, V.-C. Di Maio, R. Salpini, A. Bertoli, V. Micheli, G. Gubertini, and S. Romano et al. Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen J Infect 67 2013 303 312
-
(2013)
J Infect
, vol.67
, pp. 303-312
-
-
Cento, V.1
Van Hemert, F.2
Neumann-Fraune, M.3
Mirabelli, C.4
Di Maio, V.-C.5
Salpini, R.6
Bertoli, A.7
Micheli, V.8
Gubertini, G.9
Romano, S.10
-
52
-
-
84862956659
-
RtL180M mutation of hepatitis B virus is closely associated with frequent virological resistance to adefovir dipivoxil therapy
-
Y.-S. Lee, Y.-H. Chung, J.A. Kim, Y.J. Jin, W.H. Park, S.E. Kim, D. Lee, J.H. Shim, K.M. Kim, and Y.S. Lim et al. rtL180M mutation of hepatitis B virus is closely associated with frequent virological resistance to adefovir dipivoxil therapy J Gastroenterol Hepatol 27 2012 300 305
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 300-305
-
-
Lee, Y.-S.1
Chung, Y.-H.2
Kim, J.A.3
Jin, Y.J.4
Park, W.H.5
Kim, S.E.6
Lee, D.7
Shim, J.H.8
Kim, K.M.9
Lim, Y.S.10
-
53
-
-
49649120227
-
Hepatitis B virus genotype A2 harbours an L217R polymorphism which may account for a lower response to adefovir
-
M. Bottecchia, A. Madejón, J. Sheldon, J. García-Samaniego, P. Barreiro, and V. Soriano Hepatitis B virus genotype A2 harbours an L217R polymorphism which may account for a lower response to adefovir J Antimicrob Chemother 62 2008 626 627
-
(2008)
J Antimicrob Chemother
, vol.62
, pp. 626-627
-
-
Bottecchia, M.1
Madejón, A.2
Sheldon, J.3
García-Samaniego, J.4
Barreiro, P.5
Soriano, V.6
-
54
-
-
75649094924
-
Selection and counterselection of the rtI233V adefovir resistance mutation during antiviral therapy
-
O. Schildgen, C. Olotu, A. Funk, B. Zöllner, M. Helm, J.K. Rockstroh, and H. Sirma Selection and counterselection of the rtI233V adefovir resistance mutation during antiviral therapy J Clin Microbiol 48 2010 631 634
-
(2010)
J Clin Microbiol
, vol.48
, pp. 631-634
-
-
Schildgen, O.1
Olotu, C.2
Funk, A.3
Zöllner, B.4
Helm, M.5
Rockstroh, J.K.6
Sirma, H.7
-
55
-
-
4344627233
-
Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to lamivudine
-
DOI 10.1128/AAC.48.9.3498-3507.2004
-
D.J. Tenney, S.M. Levine, R.E. Rose, A.W. Walsh, S.P. Weinheimer, L. Discotto, M. Plym, K. Pokornowski, C.F. Yu, and P. Angus et al. Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to lamivudine Antimicrob Agents Chemother 48 2004 3498 3507 (Pubitemid 39129351)
-
(2004)
Antimicrobial Agents and Chemotherapy
, vol.48
, Issue.9
, pp. 3498-3507
-
-
Tenney, D.J.1
Levine, S.M.2
Rose, R.E.3
Walsh, A.W.4
Weinheimer, S.P.5
Discotto, L.6
Plym, M.7
Pokornowski, K.8
Yu, C.F.9
Angus, P.10
Ayres, A.11
Bartholomeusz, A.12
Sievert, W.13
Thompson, G.14
Warner, N.15
Locarnini, S.16
Colonno, R.J.17
-
56
-
-
43949100366
-
Comprehensive evaluation of hepatitis B virus reverse transcriptase substitutions associated with entecavir resistance
-
DOI 10.1002/hep.22211
-
C.J. Baldick, D.J. Tenney, C.E. Mazzucco, B.J. Eggers, R.E. Rose, K.A. Pokornowski, C.F. Yu, and R.J. Colonno Comprehensive evaluation of hepatitis B virus reverse transcriptase substitutions associated with entecavir resistance Hepatology 47 2008 1473 1482 (Pubitemid 351702731)
-
(2008)
Hepatology
, vol.47
, Issue.5
, pp. 1473-1482
-
-
Baidick, C.J.1
Tenney, D.J.2
Mazzucco, C.E.3
Eggers, B.J.4
Rose, R.E.5
Pokornowski, K.A.6
Yu, C.F.7
Colonno, R.J.8
-
57
-
-
75749138479
-
Mechanism of entecavir resistance of hepatitis B virus with viral breakthrough as determined by long-term clinical assessment and molecular docking simulation
-
M. Mukaide, Y. Tanaka, Shin-I.T., M.-F. Yuen, F. Kurbanov, O. Yokosuka, M. Sata, Y. Karino, G. Yamada, and K. Sakaguchi et al. Mechanism of entecavir resistance of hepatitis B virus with viral breakthrough as determined by long-term clinical assessment and molecular docking simulation Antimicrob Agents Chemother 54 2010 882 889
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 882-889
-
-
Mukaide, M.1
Tanaka, Y.2
Shin, I.T.3
Yuen, M.-F.4
Kurbanov, F.5
Yokosuka, O.6
Sata, M.7
Karino, Y.8
Yamada, G.9
Sakaguchi, K.10
-
58
-
-
65049086668
-
Two cases of development of entecavir resistance during entecavir treatment for nucleoside-naive chronic hepatitis B
-
H. Kobashi, S. Fujioka, M. Kawaguchi, H. Kumada, O. Yokosuka, N. Hayashi, K. Suzuki, T. Okanoue, M. Sata, and H. Tsubouchi et al. Two cases of development of entecavir resistance during entecavir treatment for nucleoside-naive chronic hepatitis B Hepatol Int 3 2009 403 410
-
(2009)
Hepatol Int
, vol.3
, pp. 403-410
-
-
Kobashi, H.1
Fujioka, S.2
Kawaguchi, M.3
Kumada, H.4
Yokosuka, O.5
Hayashi, N.6
Suzuki, K.7
Okanoue, T.8
Sata, M.9
Tsubouchi, H.10
-
59
-
-
84855545321
-
Molecular characterization of a novel entecavir mutation pattern isolated from a multi-drug refractory patient with chronic hepatitis B infection
-
E. Karatayli, S.C. Karatayli, K. Cinar, S. Gokahmetoglu, K. Güven, R. Idilman, C. Yurdaydin, and A.M. Bozdayi Molecular characterization of a novel entecavir mutation pattern isolated from a multi-drug refractory patient with chronic hepatitis B infection J Clin Virol 53 2012 130 134
-
(2012)
J Clin Virol
, vol.53
, pp. 130-134
-
-
Karatayli, E.1
Karatayli, S.C.2
Cinar, K.3
Gokahmetoglu, S.4
Güven, K.5
Idilman, R.6
Yurdaydin, C.7
Bozdayi, A.M.8
-
60
-
-
81355147296
-
Phenotypic assay of a hepatitis B virus strain carrying an rtS246T variant using a new strategy
-
J.-L. Hu, J. Cui, J.-J. Guo, W.-L. Zhang, X.-F. Cai, Z.-W. Yuan, Q.-L. Li, X.-Y. Deng, A.-Z. Zeng, and Y. Hu et al. Phenotypic assay of a hepatitis B virus strain carrying an rtS246T variant using a new strategy J Med Virol 84 2012 34 43
-
(2012)
J Med Virol
, vol.84
, pp. 34-43
-
-
Hu, J.-L.1
Cui, J.2
Guo, J.-J.3
Zhang, W.-L.4
Cai, X.-F.5
Yuan, Z.-W.6
Li, Q.-L.7
Deng, X.-Y.8
Zeng, A.-Z.9
Hu, Y.10
-
61
-
-
58149459587
-
Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir
-
M. Seifer, A. Patty, I. Serra, B. Li, and D.N. Standring Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir Antiviral Res 81 2009 147 155
-
(2009)
Antiviral Res
, vol.81
, pp. 147-155
-
-
Seifer, M.1
Patty, A.2
Serra, I.3
Li, B.4
Standring, D.N.5
-
62
-
-
84871884647
-
The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
-
B. Qin, B. Budeus, L. Cao, C. Wu, Y. Wang, X. Zhang, S. Rayner, D. Hoffmann, M. Lu, and X. Chen The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir Antiviral Res 97 2013 93 100
-
(2013)
Antiviral Res
, vol.97
, pp. 93-100
-
-
Qin, B.1
Budeus, B.2
Cao, L.3
Wu, C.4
Wang, Y.5
Zhang, X.6
Rayner, S.7
Hoffmann, D.8
Lu, M.9
Chen, X.10
-
63
-
-
25444459427
-
Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir
-
J. Sheldon, N. Camino, B. Rodés, A. Bartholomeusz, M. Kuiper, F. Tacke, M. Núñez, S. Mauss, T. Lutz, and G. Klausen et al. Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir Antivir Ther 10 2005 727 734 (Pubitemid 41376852)
-
(2005)
Antiviral Therapy
, vol.10
, Issue.6
, pp. 727-734
-
-
Sheldon, J.1
Camino, N.2
Rodes, B.3
Bartholomeusz, A.4
Kuiper, M.5
Tacke, F.6
Nunez, M.7
Mauss, S.8
Lutz, T.9
Klausen, G.10
Locarnini, S.11
Soriano, V.12
-
64
-
-
84863108115
-
The YMDD and rtA194T mutations result in decreased replication capacity in wild-type HBV as well as in HBV with precore and basal core promoter mutations
-
Y. Zhu, M. Curtis, and K. Borroto-Esoda The YMDD and rtA194T mutations result in decreased replication capacity in wild-type HBV as well as in HBV with precore and basal core promoter mutations Antivir Chem Chemother 22 2011 13 22
-
(2011)
Antivir Chem Chemother
, vol.22
, pp. 13-22
-
-
Zhu, Y.1
Curtis, M.2
Borroto-Esoda, K.3
-
65
-
-
77950821986
-
Identification and characterization of clevudine-resistant mutants of hepatitis B virus isolated from chronic hepatitis B patients
-
S.Y. Kwon, Y.K. Park, S.H. Ahn, E.S. Cho, W.H. Choe, C.H. Lee, B.K. Kim, S.Y. Ko, H.S. Choi, and E.S. Park et al. Identification and characterization of clevudine-resistant mutants of hepatitis B virus isolated from chronic hepatitis B patients J Virol 84 2010 4494 4503
-
(2010)
J Virol
, vol.84
, pp. 4494-4503
-
-
Kwon, S.Y.1
Park, Y.K.2
Ahn, S.H.3
Cho, E.S.4
Choe, W.H.5
Lee, C.H.6
Kim, B.K.7
Ko, S.Y.8
Choi, H.S.9
Park, E.S.10
-
66
-
-
0142092372
-
The Hepatitis B Virus Polymerase Mutation rtV173L Is Selected during Lamivudine Therapy and Enhances Viral Replication In Vitro
-
DOI 10.1128/JVI.77.21.11833-11841.2003
-
W.E. Delaney 4th, H. Yang, C.E. Westland, K. Das, E. Arnold, C.S. Gibbs, M.D. Miller, and S. Xiong The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro J Virol 77 2003 11833 11841 (Pubitemid 37271680)
-
(2003)
Journal of Virology
, vol.77
, Issue.21
, pp. 11833-11841
-
-
Delaney, W.E.1
Yang, H.2
Westland, C.E.3
Das, K.4
Arnold, E.5
Gibbs, C.S.6
Miller, M.D.7
Xiong, S.8
-
67
-
-
24044526915
-
Cross-resistance testing of next-generation nucleoside and nucleotide analogues against lamivudine-resistant HBV
-
H. Yang, X. Qi, A. Sabogal, M. Miller, S. Xiong, and W.E. Delaney 4th Cross-resistance testing of next-generation nucleoside and nucleotide analogues against lamivudine-resistant HBV Antivir Ther 10 2005 625 633 (Pubitemid 41224954)
-
(2005)
Antiviral Therapy
, vol.10
, Issue.5
, pp. 625-633
-
-
Yang, H.1
Qi, X.2
Sabogal, A.3
Miller, M.4
Xiong, S.5
Delaney IV, W.E.6
-
68
-
-
0035041976
-
Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC)
-
DOI 10.1128/JVI.75.10.4771-4779.2001
-
K. Das, X. Xiong, H. Yang, C.E. Westland, C.S. Gibbs, S.G. Sarafianos, and E. Arnold Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC) J Virol 75 2001 4771 4779 (Pubitemid 32381520)
-
(2001)
Journal of Virology
, vol.75
, Issue.10
, pp. 4771-4779
-
-
Das, K.1
Xiong, X.2
Yang, H.3
Westland, C.E.4
Gibbs, C.S.5
Sarafianos, S.G.6
Arnold, E.7
-
69
-
-
0035018490
-
Cross-resistance testing of antihepadnaviral compounds using novel recombinant baculoviruses which encode drug-resistant strains of hepatitis B virus
-
DOI 10.1128/AAC.45.6.1705-1713.2001
-
W.E. Delaney 4th, R. Edwards, D. Colledge, T. Shaw, J. Torresi, T.G. Miller, H.C. Isom, C.T. Bock, M.P. Manns, C. Trautwein, and S. Locarnini Cross-resistance testing of antihepadnaviral compounds using novel recombinant baculoviruses which encode drug-resistant strains of hepatitis B virus Antimicrob Agents Chemother 45 2001 1705 1713 (Pubitemid 32466338)
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, Issue.6
, pp. 1705-1713
-
-
Delaney IV, W.E.1
Edwards, R.2
Colledge, D.3
Shaw, T.4
Torresi, J.5
Miller, T.G.6
Isom, H.C.7
Bock, C.T.8
Manns, M.P.9
Trautwein, C.10
Locarnini, S.11
-
70
-
-
0035114188
-
The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance
-
S.K. Ono, N. Kato, Y. Shiratori, J. Kato, T. Goto, R.F. Schinazi, F.J. Carrilho, and M. Omata The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance J Clin Invest 107 2001 449 455 (Pubitemid 32167991)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.4
, pp. 449-455
-
-
Ono, S.K.1
Kato, N.2
Shiratori, Y.3
Kato, J.4
Goto, T.5
Schinazi, R.F.6
Carrilho, F.J.7
Omata, M.8
-
71
-
-
17944372114
-
In vitro susceptibilities of wild-type or drug-resistant hepatitis B virus to (-)-β-D-2,6-diaminopurine dioxolane and 2′-fluoro-5-methyl- β-L-arabinofuranosyluracil
-
DOI 10.1128/AAC.45.9.2495-2501.2001
-
R. Chin, T. Shaw, J. Torresi, V. Sozzi, C. Trautwein, T. Bock, M. Manns, H. Isom, P. Furman, and S. Locarnini In vitro susceptibilities of wild-type or drug-resistant hepatitis B virus to (-)-β-d-2,6-diaminopurine dioxolane and 2′-fluoro-5-methyl-β-l-arabinofuranosyluracil Antimicrob Agents Chemother 45 2001 2495 2501 (Pubitemid 32801901)
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, Issue.9
, pp. 2495-2501
-
-
Chin, R.1
Shaw, T.2
Torresi, J.3
Sozzi, V.4
Trautwein, C.5
Bock, T.6
Manns, M.7
Isom, H.8
Furman, P.9
Locarnini, S.10
-
72
-
-
0031793849
-
Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro
-
X. Xiong, C. Flores, H. Yang, J.J. Toole, and C.S. Gibbs Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro Hepatology 28 1998 1669 1673 (Pubitemid 28549139)
-
(1998)
Hepatology
, vol.28
, Issue.6
, pp. 1669-1673
-
-
Xiong, X.1
Flores, C.2
Yang, H.3
Toole, J.J.4
Gibbs, C.S.5
-
73
-
-
0032693145
-
Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors
-
S.K. Ono-Nita, N. Kato, Y. Shiratori, K.H. Lan, H. Yoshida, F.J. Carrilho, and M. Omata Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors J Clin Invest 103 1999 1635 1640 (Pubitemid 29534357)
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.12
, pp. 1635-1640
-
-
Ono-Nita, S.K.1
Kato, N.2
Shiratori, Y.3
Lan, K.-H.4
Yoshida, H.5
Carrilho, F.J.6
Omata, M.7
-
74
-
-
20044375767
-
Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir
-
DOI 10.1002/hep.20723
-
M.-N. Brunelle, A.-C. Jacquard, C. Pichoud, D. Durantel, S. Carrouée-Durantel, J.-P. Villeneuve, C. Trépo, and F. Zoulim Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir Hepatology 41 2005 1391 1398 (Pubitemid 40770292)
-
(2005)
Hepatology
, vol.41
, Issue.6
, pp. 1391-1398
-
-
Brunelle, M.-N.1
Jacquard, A.-C.2
Pichoud, C.3
Durantel, D.4
Carrouee-Durantel, S.5
Villeneuve, J.-P.6
Trepo, C.7
Zoulim, F.8
-
75
-
-
33644642052
-
In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2′,3′-dideoxy-3′-fluoroguanosine
-
DOI 10.1128/AAC.50.3.955-961.2006
-
A.-C. Jacquard, M.-N. Brunelle, C. Pichoud, D. Durantel, S. Carrouée-Durantel, C. Trepo, and F. Zoulim In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2′,3′-dideoxy-3′-fluoroguanosine Antimicrob Agents Chemother 50 2006 955 961 (Pubitemid 43327800)
-
(2006)
Antimicrobial Agents and Chemotherapy
, vol.50
, Issue.3
, pp. 955-961
-
-
Jacquard, A.-C.1
Brunelle, M.-N.2
Pichoud, C.3
Durantel, D.4
Carrouee-Durantel, S.5
Trepo, C.6
Zoulim, F.7
-
76
-
-
34249075512
-
In vitro susceptibility of adefovir-associated hepatitis B virus polymerase mutations to other antiviral agents
-
X. Qi, S. Xiong, H. Yang, M. Miller, and W.E. Delaney 4th In vitro susceptibility of adefovir-associated hepatitis B virus polymerase mutations to other antiviral agents Antivir Ther 12 2007 355 362 (Pubitemid 46787980)
-
(2007)
Antiviral Therapy
, vol.12
, Issue.3
, pp. 355-362
-
-
Qi, X.1
Xiong, S.2
Yang, H.3
Miller, M.4
Delaney IV, W.E.5
-
77
-
-
84875010204
-
Molecular basis of human immunodeficiency virus type 1 drug resistance: Overview and recent developments
-
L. Menéndez-Arias Molecular basis of human immunodeficiency virus type 1 drug resistance: overview and recent developments Antiviral Res 98 2013 93 120
-
(2013)
Antiviral Res
, vol.98
, pp. 93-120
-
-
Menéndez-Arias, L.1
-
78
-
-
41949114325
-
Pre-steady-state kinetic studies establish entecavir 5′- triphosphate as a substrate for HIV-1 reverse transcriptase
-
R.A. Domaoal, M. McMahon, C.L. Thio, C.M. Bailey, J. Tirado-Rives, A. Obikhod, M. Detorio, K.L. Rapp, R.F. Siliciano, R.F. Schinazi, and K.S. Anderson Pre-steady-state kinetic studies establish entecavir 5′-triphosphate as a substrate for HIV-1 reverse transcriptase J Biol Chem 283 2008 5452 5459
-
(2008)
J Biol Chem
, vol.283
, pp. 5452-5459
-
-
Domaoal, R.A.1
McMahon, M.2
Thio, C.L.3
Bailey, C.M.4
Tirado-Rives, J.5
Obikhod, A.6
Detorio, M.7
Rapp, K.L.8
Siliciano, R.F.9
Schinazi, R.F.10
Anderson, K.S.11
-
79
-
-
34250722018
-
The HBV drug entecavir - Effects on HIV-1 replication and resistance
-
DOI 10.1056/NEJMoa067710
-
M.A. McMahon, B.L. Jilek, T.P. Brennan, L. Shen, Y. Zhou, M. Wind-Rotolo, S. Xing, S. Bhat, B. Hale, and R. Hegarty et al. The HBV drug entecavir - effects on HIV-1 replication and resistance N Engl J Med 356 2007 2614 2621 (Pubitemid 46961006)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.25
, pp. 2614-2621
-
-
McMahon, M.A.1
Jilek, B.L.2
Brennan, T.P.3
Shen, L.4
Zhou, Y.5
Wind-Rotolo, M.6
Xing, S.7
Bhat, S.8
Hale, B.9
Hegarty, R.10
Chong, C.R.11
Liu, J.O.12
Siliciano, R.F.13
Thio, C.L.14
-
80
-
-
43249116834
-
The anti-HIV activity of entecavir: A multicentre evaluation of lamivudine-experienced and lamivudine-naive patients
-
DOI 10.1097/QAD.0b013e3282ffde91, PII 0000203020080511000005
-
J. Sasadeusz, J. Audsley, A. Mijch, R. Baden, J. Caro, H. Hunter, G. Matthews, M.A. McMahon, S.A. Olender, and R.F. Siliciano et al. The anti-HIV activity of entecavir: a multicentre evaluation of lamivudine-experienced and lamivudine-naive patients AIDS 22 2008 947 955 (Pubitemid 351652245)
-
(2008)
AIDS
, vol.22
, Issue.8
, pp. 947-955
-
-
Sasadeusz, J.1
Audsley, J.2
Mijch, A.3
Baden, R.4
Caro, J.5
Hunter, H.6
Matthews, G.7
McMahon, M.A.8
Olender, S.A.9
Siliciano, R.F.10
Lewin, S.R.11
Thio, C.L.12
-
81
-
-
84861235025
-
Antiviral therapies: Focus on hepatitis B reverse transcriptase
-
E. Michailidis, K.A. Kirby, A. Hachiya, W. Yoo, S.P. Hong, S.-O. Kim, W.R. Folk, and S.G. Sarafianos Antiviral therapies: focus on hepatitis B reverse transcriptase Int J Biochem Cell Biol 44 2012 1060 1071
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1060-1071
-
-
Michailidis, E.1
Kirby, K.A.2
Hachiya, A.3
Yoo, W.4
Hong, S.P.5
Kim, S.-O.6
Folk, W.R.7
Sarafianos, S.G.8
-
82
-
-
47149111970
-
The antiviral drug selected hepatitis B virus rtA181T/sW172 mutant has a dominant negative secretion defect and alters the typical profile of viral rebound
-
DOI 10.1002/hep.22295
-
N. Warner, and S. Locarnini The antiviral drug selected hepatitis B virus rtA181T/sW172* mutant has a dominant negative secretion defect and alters the typical profile of viral rebound Hepatology 48 2008 88 98 (Pubitemid 351975534)
-
(2008)
Hepatology
, vol.48
, Issue.1
, pp. 88-98
-
-
Warner, N.1
Locarnini, S.2
-
83
-
-
84900990537
-
The impact of the hepatitis B virus polymerase rtA181T mutation on replication and drug resistance is potentially affected by overlapping changes in surface gene
-
10.1128/JVI.00635-14
-
S.H. Ahn, Y.K. Park, E.-S. Park, J.H. Kim, D.H. Kim, K.-H. Lim, M.S. Jang, W.H. Choe, S.Y. Ko, and I.-K. Sung et al. The impact of the hepatitis B virus polymerase rtA181T mutation on replication and drug resistance is potentially affected by overlapping changes in surface gene J Virol 2014 10.1128/JVI.00635-14
-
(2014)
J Virol
-
-
Ahn, S.H.1
Park, Y.K.2
Park, E.-S.3
Kim, J.H.4
Kim, D.H.5
Lim, K.-H.6
Jang, M.S.7
Choe, W.H.8
Ko, S.Y.9
Sung, I.-K.10
-
84
-
-
84862909207
-
Entecavir plus adefovir combination treatment for chronic hepatitis B patients after failure of nucleoside/nucleotide analogues
-
Y.S. Lim, T.H. Lee, N.Y. Heo, J.H. Shim, H.C. Lee, and D.J. Suh Entecavir plus adefovir combination treatment for chronic hepatitis B patients after failure of nucleoside/nucleotide analogues Antivir Ther 17 2012 53 60
-
(2012)
Antivir Ther
, vol.17
, pp. 53-60
-
-
Lim, Y.S.1
Lee, T.H.2
Heo, N.Y.3
Shim, J.H.4
Lee, H.C.5
Suh, D.J.6
-
85
-
-
84893707879
-
Efficacy of 2 years of entecavir plus adefovir therapy in patients with chronic hepatitis B who had failed on prior nucleos(t)ide analog treatment
-
X. Wang, C. Zhang, Y. Zhu, Y. Xiong, and Y. Wang Efficacy of 2 years of entecavir plus adefovir therapy in patients with chronic hepatitis B who had failed on prior nucleos(t)ide analog treatment Antiviral Res 103 2014 71 77
-
(2014)
Antiviral Res
, vol.103
, pp. 71-77
-
-
Wang, X.1
Zhang, C.2
Zhu, Y.3
Xiong, Y.4
Wang, Y.5
-
86
-
-
42949174825
-
Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting
-
F. Li, H. Maag, and T. Alfredson Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting J Pharm Sci 97 2008 1109 1134
-
(2008)
J Pharm Sci
, vol.97
, pp. 1109-1134
-
-
Li, F.1
Maag, H.2
Alfredson, T.3
-
87
-
-
66149096185
-
Pharmacokinetics of LB80331 and LB80317 following oral administration of LB80380, a new antiviral agent for chronic hepatitis B (CHB), in healthy adult subjects, CHB patients, and mice
-
M.-F. Yuen, S.-H. Lee, H.-M. Kang, C.R. Kim, J. Kim, V. Ngai, and C.-L. Lai Pharmacokinetics of LB80331 and LB80317 following oral administration of LB80380, a new antiviral agent for chronic hepatitis B (CHB), in healthy adult subjects, CHB patients, and mice Antimicrob Agents Chemother 53 2009 1779 1785
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 1779-1785
-
-
Yuen, M.-F.1
Lee, S.-H.2
Kang, H.-M.3
Kim, C.R.4
Kim, J.5
Ngai, V.6
Lai, C.-L.7
-
88
-
-
84899984444
-
Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B
-
10.1136/gutjnl-2013-305138
-
C.L. Lai, S.H. Ahn, K.S. Lee, S.H. Um, M. Cho, S.K. Yoon, J.W. Lee, N.H. Park, Y.O. Kweon, and J.H. Sohn et al. Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B Gut 2013 10.1136/gutjnl-2013-305138
-
(2013)
Gut
-
-
Lai, C.L.1
Ahn, S.H.2
Lee, K.S.3
Um, S.H.4
Cho, M.5
Yoon, S.K.6
Lee, J.W.7
Park, N.H.8
Kweon, Y.O.9
Sohn, J.H.10
-
89
-
-
84884542210
-
β-Thujaplicinol inhibits hepatitis b virus replication by blocking the viral ribonuclease h activity
-
Y. Hu, X. Cheng, F. Cao, A. Huang, and J.E. Tavis β-Thujaplicinol inhibits hepatitis B virus replication by blocking the viral ribonuclease H activity Antiviral Res 99 2013 221 229
-
(2013)
Antiviral Res
, vol.99
, pp. 221-229
-
-
Hu, Y.1
Cheng, X.2
Cao, F.3
Huang, A.4
Tavis, J.E.5
-
90
-
-
84875066869
-
The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes
-
J.E. Tavis, X. Cheng, Y. Hu, M. Totten, F. Cao, E. Michailidis, R. Aurora, M.J. Meyers, E.J. Jacobsen, M.A. Parniak, and S.G. Sarafianos The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes PLoS Pathog 9 2013 e1003125
-
(2013)
PLoS Pathog
, vol.9
, pp. 1003125
-
-
Tavis, J.E.1
Cheng, X.2
Hu, Y.3
Totten, M.4
Cao, F.5
Michailidis, E.6
Aurora, R.7
Meyers, M.J.8
Jacobsen, E.J.9
Parniak, M.A.10
Sarafianos, S.G.11
-
91
-
-
84866177939
-
Carbonyl J acid derivatives block protein priming of hepadnaviral P protein and DNA-dependent DNA synthesis activity of hepadnaviral nucleocapsids
-
Y.X. Wang, Y.M. Wen, and M. Nassal Carbonyl J acid derivatives block protein priming of hepadnaviral P protein and DNA-dependent DNA synthesis activity of hepadnaviral nucleocapsids J Virol 86 2012 10079 10092
-
(2012)
J Virol
, vol.86
, pp. 10079-10092
-
-
Wang, Y.X.1
Wen, Y.M.2
Nassal, M.3
-
92
-
-
84856514985
-
IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
-
L. Belloni, L. Allweiss, F. Guerrieri, N. Pediconi, T. Volz, T. Pollicino, J. Petersen, G. Raimondo, M. Dandri, and M. Levrero IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome J Clin Invest 122 2012 529 537
-
(2012)
J Clin Invest
, vol.122
, pp. 529-537
-
-
Belloni, L.1
Allweiss, L.2
Guerrieri, F.3
Pediconi, N.4
Volz, T.5
Pollicino, T.6
Petersen, J.7
Raimondo, G.8
Dandri, M.9
Levrero, M.10
-
93
-
-
84896029673
-
Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA
-
J. Lucifora, Y. Xia, F. Reisinger, K. Zhang, D. Stadler, X. Cheng, M.F. Sprinzl, H. Koppensteiner, Z. Makowska, and T. Volz et al. Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA Science 343 2014 1221 1228
-
(2014)
Science
, vol.343
, pp. 1221-1228
-
-
Lucifora, J.1
Xia, Y.2
Reisinger, F.3
Zhang, K.4
Stadler, D.5
Cheng, X.6
Sprinzl, M.F.7
Koppensteiner, H.8
Makowska, Z.9
Volz, T.10
|