Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates

EMBO Journal

Volumn 33, Issue 10, 2014, Pages 1159-1176

  Besche, Henrike C ^a   Sha, Zhe ^a   Kukushkin, Nikolay V ^a   Peth, Andreas ^a   Hock, Eva Maria ^a   Kim, Woong ^a   Gygi, Steven ^a   Gutierrez, Juan A ^b   Liao, Hua ^b   Dick, Lawrence ^b   Goldberg, Alfred L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

26S proteasomes; Proteasome inhibitors; Proteasome regulation; Ube3c Hul5; Ubiquitination

Indexed keywords

ARSENIC TRIOXIDE; BIOLOGICAL MARKER; PROTEASOME; RECEPTOR SUBUNIT; RPN13 PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UBIQUITINATED PROTEIN; UNCLASSIFIED DRUG; ADRM1 PROTEIN, HUMAN; ATP DEPENDENT 26S PROTEASE; MEMBRANE PROTEIN;

ARTICLE; AUTOUBIQUITINATION; BINDING AFFINITY; CONTROLLED STUDY; HEAT SHOCK; HUMAN; INHIBITION KINETICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; STRESS; UBIQUITINATION; CELL LINE; GENETICS; METABOLISM; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; HUMANS; MEMBRANE GLYCOPROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITINATION;

EID: 84900862275     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1002/embj.201386906     Document Type: Article

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