Differential effects of the mitochondrial uncoupling agent, 2,4-dinitrophenol, or the nitroxide antioxidant, tempol, on synaptic or nonsynaptic mitochondria after spinal cord injury

Journal of Neuroscience Research

Volumn 87, Issue 1, 2009, Pages 130-140

  Patel, Samir P ^a   Sullivan, Patrick G ^a   Pandya, Jignesh D ^a   Rabchevsky, Alexander G ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Electron transport system; Excitotoxicity; Mitochondrial bioenergetics; Mitochondrial membrane potential ( ); Mitochondrial permeability transition; Oxidative damage

Indexed keywords

2,4 DINITROPHENOL; CALCIUM ION; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; TEMPOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BIOENERGY; CELL POPULATION; CONTROLLED STUDY; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFICACY; DRUG MECHANISM; FEMALE; GLIA CELL; NERVE CELL; NEUROPROTECTION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; SYNAPSE; SYNAPTOSOME;

2,4-DINITROPHENOL; ALDEHYDES; ANIMALS; ANTIOXIDANTS; CELL RESPIRATION; CYCLIC N-OXIDES; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT COMPLEX I; ENERGY METABOLISM; FEMALE; MITOCHONDRIA; PROTEIN CARBONYLATION; RATS; RATS, SPRAGUE-DAWLEY; SPIN LABELS; SPINAL CORD DISEASES; TIME FACTORS; TYROSINE; UNCOUPLING AGENTS;

EID: 63249086847     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21814     Document Type: Article

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