P38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice

BMC Pulmonary Medicine

Volumn 14, Issue 1, 2014, Pages

  Marumo, Satoshi ^a   Hoshino, Yuma ^a   Kiyokawa, Hirofumi ^a   Tanabe, Naoya ^a   Sato, Atsuyasu ^a   Ogawa, Emiko ^a   Muro, Shigeo ^a   Hirai, Toyohiro ^a   Mishima, Michiaki ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Animal model; Chronic obstructive pulmonary disease; Disease susceptibility; Molecular targeted therapy; Signal transduction

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CELL DNA; CIGARETTE SMOKE; CXCL3 CHEMOKINE; MACROPHAGE ELASTASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL MARKER; PASSIVE SMOKING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CIGARETTE SMOKE-INDUCED EMPHYSEMA; CONTROLLED STUDY; DISEASE MODEL; DISEASE PREDISPOSITION; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INHIBITION; INFANT; LONG TERM EXPOSURE; LUNG INJURY; MALE; MOUSE; MOUSE MODEL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PROTEIN EXPRESSION; UPREGULATION; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; LUNG EMPHYSEMA; LUNG LAVAGE; METABOLISM; PASSIVE SMOKING; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PROCEDURES; RANDOMIZATION; REFERENCE VALUE; SMOKING; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYMERASE CHAIN REACTION; PULMONARY EMPHYSEMA; RANDOM ALLOCATION; REFERENCE VALUES; SMOKING; TOBACCO SMOKE POLLUTION;

EID: 84900846903     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/1471-2466-14-79     Document Type: Article

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