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Volumn 133, Issue 3, 2010, Pages 835-846

Astrocytes within multiple sclerosis lesions upregulate sodium channel Nav1.5

Author keywords

Brain tumour; Multiple sclerosis; Reactive astrocytes; Sodium channels; Stroke

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); POTASSIUM PUMP; VOLTAGE GATED SODIUM CHANNEL;

EID: 77950223688     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awq003     Document Type: Article
Times cited : (71)

References (61)
  • 1
    • 0030041548 scopus 로고    scopus 로고
    • A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons
    • Akopian AN, Sivilotti L, Wood JN. A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons. Nature 1996; 379: 257-262.
    • (1996) Nature , vol.379 , pp. 257-262
    • Akopian, A.N.1    Sivilotti, L.2    Wood, J.N.3
  • 2
    • 0029869927 scopus 로고    scopus 로고
    • An ultrastructural study of phagocytic activity of astrocytes in adult rat brain
    • Al-Ali SY, Al-Hussain SM. An ultrastructural study of phagocytic activity of astrocytes in adult rat brain. J Anat 1996; 188: 257-262.
    • (1996) J Anat , vol.188 , pp. 257-262
    • Al-Ali, S.Y.1    Al-Hussain, S.M.2
  • 3
    • 0029592005 scopus 로고
    • Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis
    • Bagasra O, Michaels FH, Zheng YM, Bobroski LE, Spitsin SV, Fu ZF, et al. Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis. Proc Natl Acad Sci 1995; 92: 12041-12045.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 12041-12045
    • Bagasra, O.1    Michaels, F.H.2    Zheng, Y.M.3    Bobroski, L.E.4    Spitsin, S.V.5    Fu, Z.F.6
  • 4
    • 0026095969 scopus 로고
    • Blockade of cardiac sodium channels by amitriptyline and diphenylhydantoin, Evidence for two use-dependent binding sites
    • Barber MJ, Starmer CF, Grant AO. Blockade of cardiac sodium channels by amitriptyline and diphenylhydantoin. Evidence for two use-dependent binding sites. Circ Res 1991; 69: 677-696.
    • (1991) Circ Res , vol.69 , pp. 677-696
    • Barber, M.J.1    Starmer, C.F.2    Grant, A.O.3
  • 5
    • 0024644391 scopus 로고
    • Glial and neuronal forms of the voltage-dependent sodium channel: Characteristics and cell-type distribution
    • Barres BA, Chun LL, Corey DP. Glial and neuronal forms of the voltage-dependent sodium channel: characteristics and cell-type distribution. Neuron 1989; 2: 1375-1388.
    • (1989) Neuron , vol.2 , pp. 1375-1388
    • Barres, B.A.1    Chun, L.L.2    Corey, D.P.3
  • 6
    • 0013008921 scopus 로고    scopus 로고
    • Axonal protection mediated by flecai-nide therapy in experimental inflammatory demyelinating disease
    • Bechtold DA, Kapoor R, Smith KJ. Axonal protection mediated by flecai-nide therapy in experimental inflammatory demyelinating disease. J Neurol 2002; 249 (Suppl.1): S204.
    • (2002) J Neurol , vol.249 , Issue.SUPPL.1
    • Bechtold, D.A.1    Kapoor, R.2    Smith, K.J.3
  • 7
    • 2142760098 scopus 로고    scopus 로고
    • Axonal protection using flecainide in experimental autoimmune encephalomyelitis
    • Bechtold DA, Kapoor R, Smith KJ. Axonal protection using flecainide in experimental autoimmune encephalomyelitis. Ann Neurol 2004; 55: 607-616.
    • (2004) Ann Neurol , vol.55 , pp. 607-616
    • Bechtold, D.A.1    Kapoor, R.2    Smith, K.J.3
  • 8
    • 33744489487 scopus 로고    scopus 로고
    • Axonal protection achieved in a model of multiple sclerosis using lamo-trigine
    • Bechtold DA, Miller SJ, Dawson AC, Sun Y, Kapoor R, Berry D, et al. Axonal protection achieved in a model of multiple sclerosis using lamo-trigine. J Neurol 2006; 253: 1542-1551.
    • (2006) J Neurol , vol.253 , pp. 1542-1551
    • Bechtold, D.A.1    Miller, S.J.2    Dawson, A.C.3    Sun, Y.4    Kapoor, R.5    Berry, D.6
  • 9
    • 0021955851 scopus 로고
    • The presence of voltage-gated sodium, potassium and chloride channels in rat cultured astrocytes
    • Bevan S, Chiu SY, Gray PT, Ritchie JM. The presence of voltage-gated sodium, potassium and chloride channels in rat cultured astrocytes. Proc R Soc Lond B Biol Sci 1985; 225: 299-313.
    • (1985) Proc R Soc Lond B Biol Sci , vol.225 , pp. 299-313
    • Bevan, S.1    Chiu, S.Y.2    Gray, P.T.3    Ritchie, J.M.4
  • 10
    • 0023508557 scopus 로고
    • Voltage-gated ionic channels in rat cultured astrocytes, reactive astrocytes and an astro-cyte-oligodendrocyte progenitor cell
    • Bevan S, Lindsay RM, Perkins MN, Raff MC. Voltage-gated ionic channels in rat cultured astrocytes, reactive astrocytes and an astro-cyte-oligodendrocyte progenitor cell. J Physiol (Paris) 1987; 82: 327-335.
    • (1987) J Physiol (Paris , vol.82 , pp. 327-335
    • Bevan, S.1    Lindsay, R.M.2    Perkins, M.N.3    Raff, M.C.4
  • 11
    • 7144223407 scopus 로고    scopus 로고
    • Glial cells have heart: RH1 Na+ channel mRNA and protein in spinal cord astrocytes
    • Black JA, Dib-Hajj S, Cohen S, Hinson AW, Waxman SG. Glial cells have heart: rH1 Na+ channel mRNA and protein in spinal cord astrocytes. Glia 1998; 23: 200-208.
    • (1998) Glia , vol.23 , pp. 200-208
    • Black, J.A.1    Dib-Hajj, S.2    Cohen, S.3    Hinson, A.W.4    Waxman, S.G.5
  • 12
    • 69449105146 scopus 로고    scopus 로고
    • Sodium channel activity modulates multiple functions in microglia
    • Black JA, Liu S, Waxman SG. Sodium channel activity modulates multiple functions in microglia. Glia 2009; 57: 1072-1081.
    • (2009) Glia , vol.57 , pp. 1072-1081
    • Black, J.A.1    Liu, S.2    Waxman, S.G.3
  • 14
    • 0029795459 scopus 로고    scopus 로고
    • Sodium channel expression: A dynamic process in neurons and non-neuronal cells
    • Black JA, Waxman SG. Sodium channel expression: a dynamic process in neurons and non-neuronal cells. Dev Neurosci 1996; 18: 139-152.
    • (1996) Dev Neurosci , vol.18 , pp. 139-152
    • Black, J.A.1    Waxman, S.G.2
  • 15
    • 0028542079 scopus 로고
    • Type II sodium channels in spinal cord astrocytes in situ: Immunocytochem-ical observations
    • Black JA, Westenbroek R, Ransom BR, Catterall WA, Waxman SG. Type II sodium channels in spinal cord astrocytes in situ: immunocytochem-ical observations. Glia 1994a; 12: 219-227.
    • (1994) Glia , vol.12 , pp. 219-227
    • Black, J.A.1    Westenbroek, R.2    Ransom, B.R.3    Catterall, W.A.4    Waxman, S.G.5
  • 16
    • 0028265293 scopus 로고
    • Sodium channel mRNAs in cultured spinal cord astrocytes: In situ hybridization in identified cell types
    • Black JA, Yokoyama S, Waxman SG, Oh Y, Zur KB, Sontheimer H, et al. Sodium channel mRNAs in cultured spinal cord astrocytes: in situ hybridization in identified cell types. Brain Res Mol Brain Res 1994b; 23: 235-245.
    • (1994) Brain Res Mol Brain Res , vol.23 , pp. 235-245
    • Black, J.A.1    Yokoyama, S.2    Waxman, S.G.3    Oh, Y.4    Zur, K.B.5    Sontheimer, H.6
  • 17
    • 33846269623 scopus 로고    scopus 로고
    • The neonatal splice variant of Nav1.5 potentiates in vitro invasive behaviour of MDA-MB-231 human breast cancer cells
    • Brackenbury WJ, Chioni AM, Diss JK, Djamgoz MB. The neonatal splice variant of Nav1.5 potentiates in vitro invasive behaviour of MDA-MB-231 human breast cancer cells. Breast Cancer Res Treat 2007; 101: 149-160.
    • (2007) Breast Cancer Res Treat , vol.101 , pp. 149-160
    • Brackenbury, W.J.1    Chioni, A.M.2    Diss, J.K.3    Djamgoz, M.B.4
  • 18
    • 65549133825 scopus 로고    scopus 로고
    • Regulation of podosome formation in macrophages by a splice variant of the sodium channel SCN8A
    • Carrithers MD, Chatterjee G, Carrithers LM, Offoha R, Iheagwara U, Rahner C, et al. Regulation of podosome formation in macrophages by a splice variant of the sodium channel SCN8A. J Biol Chem 2009; 284: 8114-8126.
    • (2009) J Biol Chem , vol.284 , pp. 8114-8126
    • Carrithers, M.D.1    Chatterjee, G.2    Carrithers, L.M.3    Offoha, R.4    Iheagwara, U.5    Rahner, C.6
  • 19
    • 34250211729 scopus 로고    scopus 로고
    • Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification
    • Carrithers MD, Dib-Hajj S, Carrithers LM, Tokmoulina G, Pypaert M, Jonas EA, et al. Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification. J Immunol 2007; 178: 7822-7832.
    • (2007) J Immunol , vol.178 , pp. 7822-7832
    • Carrithers, M.D.1    Dib-Hajj, S.2    Carrithers, L.M.3    Tokmoulina, G.4    Pypaert, M.5    Jonas, E.A.6
  • 20
    • 29844438166 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
    • Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacol Rev 2005; 57: 397-409.
    • (2005) Pharmacol Rev , vol.57 , pp. 397-409
    • Catterall, W.A.1    Goldin, A.L.2    Waxman, S.G.3
  • 21
    • 13244258365 scopus 로고    scopus 로고
    • Sodium channels contribute to microglia/macrophage activation and function in EAE and MS
    • Craner MJ, Damarjian TG, Liu S, Hains BC, Lo AC, Black JA, et al. Sodium channels contribute to microglia/macrophage activation and function in EAE and MS. Glia 2005; 49: 220-229.
    • (2005) Glia , vol.49 , pp. 220-229
    • Craner, M.J.1    Damarjian, T.G.2    Liu, S.3    Hains, B.C.4    Lo, A.C.5    Black, J.A.6
  • 22
    • 2542619146 scopus 로고    scopus 로고
    • Molecular changes in neurons in multiple sclerosis: Altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger
    • Craner MJ, Newcombe J, Black JA, Hartle C, Cuzner ML, Waxman SG. Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger. Proc Natl Acad Sci 2004; 101: 8168-8173.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 8168-8173
    • Craner, M.J.1    Newcombe, J.2    Black, J.A.3    Hartle, C.4    Cuzner, M.L.5    Waxman, S.G.6
  • 23
    • 0032555278 scopus 로고    scopus 로고
    • NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy
    • Dib-Hajj SD, Tyrrell L, Black JA, Waxman SG. NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy. Proc Natl Acad Sci 1998; 95: 8963-8968.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 8963-8968
    • Dib-Hajj, S.D.1    Tyrrell, L.2    Black, J.A.3    Waxman, S.G.4
  • 24
    • 0035153212 scopus 로고    scopus 로고
    • Immune function of astrocytes
    • Dong Y, Benveniste EN. Immune function of astrocytes. Glia 2001; 36: 180-190.
    • (2001) Glia , vol.36 , pp. 180-190
    • Dong, Y.1    Benveniste, E.N.2
  • 26
    • 0037110631 scopus 로고    scopus 로고
    • Primary motor neurons fail to up-regulate voltage-gated sodium channel Na v)1.3/brain type III following axotomy resulting from spinal cord injury
    • Hains BC, Black JA, Waxman SG. Primary motor neurons fail to up-regulate voltage-gated sodium channel Na(v)1.3/brain type III following axotomy resulting from spinal cord injury. J Neurosci Res 2002; 70: 546-552.
    • (2002) J Neurosci Res , vol.70 , pp. 546-552
    • Hains, B.C.1    Black, J.A.2    Waxman, S.G.3
  • 29
    • 0035101513 scopus 로고    scopus 로고
    • Cultured astrocytes react to LPS with increased cyclooxygenase activity and phagocytosis
    • Kalmar B, Kittel A, Lemmens R, Kö rnyei Zs, Madarasz E. Cultured astrocytes react to LPS with increased cyclooxygenase activity and phagocytosis. Neurochem Int 2001; 38: 453-461.
    • (2001) Neurochem Int , vol.38 , pp. 453-461
    • Kalmar, B.1    Kittel, A.2    Lemmens, R.3    Környei, Z.4    Madarasz, E.5
  • 30
    • 33744497817 scopus 로고    scopus 로고
    • Neuroprotection in multiple sclerosis: Therapeutic strategies and clinical trial design
    • Kapoor R. Neuroprotection in multiple sclerosis: therapeutic strategies and clinical trial design. Curr Opin Neurol 2006; 19: 255-259.
    • (2006) Curr Opin Neurol , vol.19 , pp. 255-259
    • Kapoor, R.1
  • 31
    • 0028884322 scopus 로고
    • Electrophysiological evaluation of the sodium-channel blocker carbamazepine in healthy human subjects
    • Kennebäck G, Bergfeldt L, Tomson T. Electrophysiological evaluation of the sodium-channel blocker carbamazepine in healthy human subjects. Cardiovasc Drugs Ther 1995; 9: 709-714.
    • (1995) Cardiovasc Drugs Ther , vol.9 , pp. 709-714
    • Kennebäck, G.1    Bergfeldt, L.2    Tomson, T.3
  • 32
    • 0025278577 scopus 로고
    • A role for astroglia in active demyelination suggested by Class II MHC expression and ultrastructure study
    • Lee SC, Moore GF, Golenwsky G, Raine CS. Multiple Sclerosis: a role for astroglia in active demyelination suggested by Class II MHC expression and ultrastructure study. J Neuropath Exp Neurol 1990; 49: 122-136.
    • (1990) J Neuropath Exp Neurol , vol.49 , pp. 122-136
    • Lee, S.C.1    Moore, G.F.2    Golenwsky, G.3
  • 33
    • 0037191415 scopus 로고    scopus 로고
    • Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis
    • Lo AC, Black JA, Waxman SG. Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis. Neuroreport 2002; 13: 1909-1912.
    • (2002) Neuroreport , vol.13 , pp. 1909-1912
    • Lo, A.C.1    Black, J.A.2    Waxman, S.G.3
  • 34
    • 0242508548 scopus 로고    scopus 로고
    • Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo
    • Lo AC, Saab CY, Black JA, Waxman SG. Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo. J Neurophysiol 2003; 90: 3566-3571.
    • (2003) J Neurophysiol , vol.90 , pp. 3566-3571
    • Lo, A.C.1    Saab, C.Y.2    Black, J.A.3    Waxman, S.G.4
  • 35
    • 0031953813 scopus 로고    scopus 로고
    • Spinal cord astrocytes display a switch from TTX-sensitive to TTX-resistant sodium currents after injury-induced gliosis in vitro
    • MacFarlane SN, Sontheimer H. Spinal cord astrocytes display a switch from TTX-sensitive to TTX-resistant sodium currents after injury-induced gliosis in vitro. J Neurophysiol 1998; 79: 2222-2226.
    • (1998) J Neurophysiol , vol.79 , pp. 2222-2226
    • MacFarlane, S.N.1    Sontheimer, H.2
  • 36
    • 51349134916 scopus 로고    scopus 로고
    • Astrocytes in multiple sclerosis: A product of their environment
    • Nair A, Frederick TJ, Miller SD. Astrocytes in multiple sclerosis: a product of their environment. Cell Mol Life Sci 2008; 65: 2702-2720.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 2702-2720
    • Nair, A.1    Frederick, T.J.2    Miller, S.D.3
  • 37
    • 0027337420 scopus 로고
    • Organization and research applications of the U.K. Multiple Sclerosis Society Tissue Bank
    • Newcombe J, Cuzner ML. Organization and research applications of the U.K. Multiple Sclerosis Society Tissue Bank. J Neural Transm Suppl 1993; 39: 155-163.
    • (1993) J Neural Transm Suppl , vol.39 , pp. 155-163
    • Newcombe, J.1    Cuzner, M.L.2
  • 39
    • 0037408006 scopus 로고    scopus 로고
    • Tissue sodium concentration in human brain tumors as measured with 23Na MR imaging
    • Ouwerkerk R, Bleich KB, Gillen JS, Pomper MG, Bottomley PA. Tissue sodium concentration in human brain tumors as measured with 23Na MR imaging. Radiology 2003; 227: 529-537.
    • (2003) Radiology , vol.227 , pp. 529-537
    • Ouwerkerk, R.1    Bleich, K.B.2    Gillen, J.S.3    Pomper, M.G.4    Bottomley, P.A.5
  • 40
    • 20444482731 scopus 로고    scopus 로고
    • Pathogenesis of multiple sclerosis
    • Prat A, Antel J. Pathogenesis of multiple sclerosis. Curr Opin Neurol 2005; 18: 225-230.
    • (2005) Curr Opin Neurol , vol.18 , pp. 225-230
    • Prat, A.1    Antel, J.2
  • 41
    • 6444220669 scopus 로고    scopus 로고
    • State-dependent trapping of flecainide in the cardiac sodium channel
    • Ramos E, O'Leary ME. State-dependent trapping of flecainide in the cardiac sodium channel. J Physiol 2004; 560: 37-49.
    • (2004) J Physiol , vol.560 , pp. 37-49
    • Ramos, E.1    O'Leary, M.E.2
  • 42
    • 0023493699 scopus 로고
    • Voltage-gated cation and anion channels in mammalian Schwann cells and astrocytes
    • Ritchie JM. Voltage-gated cation and anion channels in mammalian Schwann cells and astrocytes. J Physiol (Paris) 1987; 82: 248-257.
    • (1987) J Physiol (Paris , vol.82 , pp. 248-257
    • Ritchie, J.M.1
  • 44
    • 0026783901 scopus 로고
    • The cloned cardiac Na channel alpha-subunit expressed in Xenopus oocytes show gating and blocking properties of native channels
    • Satin J, Kyle JW, Chen M, Rogart RB, Fozzard HA. The cloned cardiac Na channel alpha-subunit expressed in Xenopus oocytes show gating and blocking properties of native channels. J Membr Biol 1992; 130: 11-22.
    • (1992) J Membr Biol , vol.130 , pp. 11-22
    • Satin, J.1    Kyle, J.W.2    Chen, M.3    Rogart, R.B.4    Fozzard, H.A.5
  • 46
    • 0026443814 scopus 로고
    • Ion channels in spinal cord astrocytes in vitro. I. Transient expression of high levels of Na+ and K+ channels
    • Sontheimer H, Black JA, Ransom BR, Waxman SG. Ion channels in spinal cord astrocytes in vitro. I. Transient expression of high levels of Na+ and K+ channels. J Neurophysiol 1992a; 68: 985-1000.
    • (1992) J Neurophysiol , vol.68 , pp. 985-1000
    • Sontheimer, H.1    Black, J.A.2    Ransom, B.R.3    Waxman, S.G.4
  • 47
    • 0030221741 scopus 로고    scopus 로고
    • Voltage-gated Na+ channels in glia: Properties and possible functions
    • Sontheimer H, Black JA, Waxman SG. Voltage-gated Na+ channels in glia: properties and possible functions. Trends Neurosci 1996; 19: 325-331.
    • (1996) Trends Neurosci , vol.19 , pp. 325-331
    • Sontheimer, H.1    Black, J.A.2    Waxman, S.G.3
  • 48
    • 0028261519 scopus 로고
    • Astrocyte Na+ channels are required for maintenance of Na+/K(+)-ATPase activity
    • Sontheimer H, Fernandez-Marques E, Ullrich N, Pappas CA, Waxman SG. Astrocyte Na+ channels are required for maintenance of Na+/K(+)-ATPase activity. J Neurosci 1994; 14(5 Pt 1): 2464-2475.
    • (1994) J Neurosci , vol.14 , Issue.5 PART 1 , pp. 2464-2475
    • Sontheimer, H.1    Fernandez-Marques, E.2    Ullrich, N.3    Pappas, C.A.4    Waxman, S.G.5
  • 49
    • 0025941921 scopus 로고
    • Two types of Na+-currents in cultured rat optic nerve astrocytes: Changes with time in culture and with age of derivation
    • Sontheimer H, Minturn JE, Black JA, Ransom BR, Waxman SG. Two types of Na+-currents in cultured rat optic nerve astrocytes: changes with time in culture and with age of derivation. J Neurosci Res 1991; 30: 275-287.
    • (1991) J Neurosci Res , vol.30 , pp. 275-287
    • Sontheimer, H.1    Minturn, J.E.2    Black, J.A.3    Ransom, B.R.4    Waxman, S.G.5
  • 50
    • 0026480934 scopus 로고
    • Different Na+ currents in P0-and P7-derived hippocampal astrocytes in vitro: Evidence for a switch in Na+ channel expression in vivo
    • Sontheimer H, Ransom BR, Waxman SG. Different Na+ currents in P0-and P7-derived hippocampal astrocytes in vitro: evidence for a switch in Na+ channel expression in vivo. Brain Res 1992b; 597: 24-29.
    • (1992) Brain Res , vol.597 , pp. 24-29
    • Sontheimer, H.1    Ransom, B.R.2    Waxman, S.G.3
  • 51
    • 0026454894 scopus 로고
    • Ion channels in spinal cord astrocytes in vitro. II. Biophysical and pharmacological analysis of two Na+ current types
    • Sontheimer H, Waxman SG. Ion channels in spinal cord astrocytes in vitro. II. Biophysical and pharmacological analysis of two Na+ current types. J Neurophysiol 1992; 68: 1001-1011.
    • (1992) J Neurophysiol , vol.68 , pp. 1001-1011
    • Sontheimer, H.1    Waxman, S.G.2
  • 52
    • 0027436695 scopus 로고
    • Differential modulation of TTX-sensitive and TTX-resistant Na+ channels in spinal cord astrocytes following activation of protein kinase C
    • Thio CL, Sontheimer H. Differential modulation of TTX-sensitive and TTX-resistant Na+ channels in spinal cord astrocytes following activation of protein kinase C. J Neurosci 1993; 13: 4889-4897.
    • (1993) J Neurosci , vol.13 , pp. 4889-4897
    • Thio, C.L.1    Sontheimer, H.2
  • 53
    • 0027536804 scopus 로고
    • Ion channels in spinal cord astro-cytes in vitro. III. Modulation of channel expression by coculture with neurons and neuron-conditioned medium
    • Thio CL, Waxman SG, Sontheimer H. Ion channels in spinal cord astro-cytes in vitro. III. Modulation of channel expression by coculture with neurons and neuron-conditioned medium. J Neurophysiol 1993; 69: 819-831.
    • (1993) J Neurophysiol , vol.69 , pp. 819-831
    • Thio, C.L.1    Waxman, S.G.2    Sontheimer, H.3
  • 54
    • 29144452878 scopus 로고    scopus 로고
    • Sodium MR imaging of acute and subacute stroke for assessment of tissue viability
    • Thulborn KR, Davis D, Snyder J, Yonas H, Kassam A. Sodium MR imaging of acute and subacute stroke for assessment of tissue viability. Neuroimaging Clin N Am 2005; 15: 639-653.
    • (2005) Neuroimaging Clin N Am , vol.15 , pp. 639-653
    • Thulborn, K.R.1    Davis, D.2    Snyder, J.3    Yonas, H.4    Kassam, A.5
  • 55
    • 12644288297 scopus 로고    scopus 로고
    • Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neruons
    • Toledo-Aral JJ, Moss BL, He Z-J, Koszowski AG, Whisenand T, Levinson SR, et al. Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neruons. Proc Natl Acad Sci 1997; 94: 1527-1532.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 1527-1532
    • Toledo-Aral, J.J.1    Moss, B.L.2    He, Z.-J.3    Koszowski, A.G.4    Whisenand, T.5    Levinson, S.R.6
  • 58
    • 0027475753 scopus 로고
    • Phagocytosis of myelin by astrocytes in explants of adult rabbit cerebral white matter maintained on Gelfoam matrix
    • Vinores SA, Herman MM. Phagocytosis of myelin by astrocytes in explants of adult rabbit cerebral white matter maintained on Gelfoam matrix. J Neuroimmunol 1993; 43: 169-176.
    • (1993) J Neuroimmunol , vol.43 , pp. 169-176
    • Vinores, S.A.1    Herman, M.M.2
  • 59
    • 40549135991 scopus 로고    scopus 로고
    • Mechanisms of disease: Sodium channels and neuroprotec-tion in multiple sclerosis-current status
    • Waxman SG. Mechanisms of disease: sodium channels and neuroprotec-tion in multiple sclerosis-current status. Nat Clin Pract Neurol 2008; 4: 159-169.
    • (2008) Nat Clin Pract Neurol , vol.4 , pp. 159-169
    • Waxman, S.G.1
  • 60
    • 34548206670 scopus 로고    scopus 로고
    • Astrocytes\friends of foes in multiple sclerosis?
    • Williams A, Piaton G, Lubetzki C. Astrocytes\friends of foes in multiple sclerosis? Glia 2007; 55: 1300-1312.
    • (2007) Glia , vol.55 , pp. 1300-1312
    • Williams, A.1    Piaton, G.2    Lubetzki, C.3
  • 61
    • 33645660002 scopus 로고    scopus 로고
    • Cho CH. Involvement of Kv1.1 and Nav1.5 in proliferation of gastric epithelial cells
    • Wu WK, Li GR, Wong HP, Hui MK, Tai EK, Lam EK, , et al. Cho CH. Involvement of Kv1.1 and Nav1.5 in proliferation of gastric epithelial cells. J Cell Physiol 2006; 207: 437-444.
    • (2006) J Cell Physiol , vol.207 , pp. 437-444
    • Wu, W.K.1    Li, G.R.2    Wong, H.P.3    Hui, M.K.4    Tai, E.K.5    Lam, E.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.