Upregulation of the Na+-coupled phosphate cotransporters NaPi-IIa and NaPi-IIb by B-RAF

Journal of Membrane Biology

Volumn 247, Issue 2, 2014, Pages 137-145

  Pakladok, Tatsiana ^a   Hosseinzadeh, Zohreh ^a   Lebedeva, Aleksandra ^a,b   Alesutan, Ioana ^a   Lang, Florian ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Russian Federation)

Author keywords

B RAF; HEK293 cells; Intestine; NaPi IIa; NaPi IIb; Phosphate uptake; Renal tubule

Indexed keywords

B RAF KINASE; PHOSPHATE; PROTEIN NAPI IIA; PROTEIN NAPI IIB; SODIUM PHOSPHATE COTRANSPORTER; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ARTICLE; BIOTINYLATION; CHEMOLUMINESCENCE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; OOCYTE; UPREGULATION; WESTERN BLOTTING; XENOPUS;

ANIMALS; HEK293 CELLS; HUMANS; INDOLES; ION TRANSPORT; MICE; OOCYTES; PHOSPHATES; PROTO-ONCOGENE PROTEINS B-RAF; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE IIA; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE IIB; SULFONAMIDES; UP-REGULATION; XENOPUS;

EID: 84900600235     PISSN: 00222631     EISSN: 14321424     Source Type: Journal    
DOI: 10.1007/s00232-013-9616-x     Document Type: Article

References (65)

1. Alesutan IS, Ureche ON, Laufer J, Klaus F, Zurn A, Lindner R, Strutz-Seebohm N, Tavare JM, Boehmer C, Palmada M, Lang UE, Seebohm G, Lang F (2010) Regulation of the glutamate transporter EAAT4 by PIKfyve. Cell Physiol Biochem 25:187-194
2. Alesutan I, Sopjani M, Munoz C, Fraser S, Kemp BE, Foller M, Lang F (2011) Inhibition of connexin 26 by the AMP-activated protein kinase. J Membr Biol 240:151-158
3. Alesutan I, Sopjani M, Dermaku-Sopjani M, Munoz C, Voelkl J, Lang F (2012) Upregulation of Na-coupled glucose transporter SGLT1 by Tau tubulin kinase 2. Cell Physiol Biochem 30:458-465
4. Allon M (1992) Effects of insulin and glucose on renal phosphate reabsorption: interactions with dietary phosphate. J Am Soc Nephrol 2:1593-1600
5. Almilaji A, Munoz C, Hosseinzadeh Z, Lang F (2013a) Upregulation of Na, Cl-coupled betaine/gamma-amino-butyric acid transporter BGT1 by Tau tubulin kinase 2. Cell Physiol Biochem 32:334-343
6. Almilaji A, Szteyn K, Fein E, Pakladok T, Munoz C, Elvira B, Towhid ST, Alesutan I, Shumilina E, Bock CT, Kandolf R, Lang F (2013b) Down-regulation of Na/K+ atpase activity by human parvovirus B19 capsid protein VP1. Cell Physiol Biochem 31:638-648
7. Bacic D, Schulz N, Biber J, Kaissling B, Murer H, Wagner CA (2003) Involvement of the MAPK-kinase pathway in the PTH-mediated regulation of the proximal tubule type IIa Na+/Pi cotransporter in mouse kidney. Pflugers Arch 446:52-60 (Pubitemid 36539533)
8. Bacic D, Lehir M, Biber J, Kaissling B, Murer H, Wagner CA (2006) The renal Na+/phosphate cotransporter NaPi-IIa is internalized via the receptor-mediated endocytic route in response to parathyroid hormone. Kidney Int 69:495-503 (Pubitemid 43164441)
9. Beck L, Leroy C, Salaun C, Margall-Ducos G, Desdouets C, Friedlander G (2009) Identification of a novel function of PiT1 critical for cell proliferation and independent of its phosphate transport activity. J Biol Chem 284:31363-31374
10. Bhandaru M, Kempe DS, Rotte A, Capuano P, Pathare G, Sopjani M, Alesutan I, Tyan L, Huang DY, Siraskar B, Judenhofer MS, Stange G, Pichler BJ, Biber J, Quintanilla-Martinez L, Wagner CA, Pearce D, Foller M, Lang F (2011) Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3. Kidney Int 80:61-67
11. Biber J, Hernando N, Forster I, Murer H (2009) Regulation of phosphate transport in proximal tubules. Pflugers Arch 458:39-52
12. Bogatikov E, Munoz C, Pakladok T, Alesutan I, Shojaiefard M, Seebohm G, Foller M, Palmada M, Bohmer C, Broer S, Lang F (2012) Up-regulation of amino acid transporter SLC6A19 activity and surface protein abundance by PKB/Akt and PIKfyve. Cell Physiol Biochem 30:1538-1546
13. Broer S, Broer A, Hamprecht B (1994) Expression of Na+-independent isoleucine transport activity from rat brain in Xenopus laevis oocytes. Biochim Biophys Acta 1192:95-100 (Pubitemid 24171546)
14. Busch AE, Wagner CA, Schuster A, Waldegger S, Biber J, Murer H, Lang F (1995) Properties of electrogenic Pi transport by a human renal brush border Na+/Pi transporter. J Am Soc Nephrol 6:1547-1551
15. Carranza A, Musolino PL, Villar M, Nowicki S (2008) Signaling cascade of insulin-induced stimulation of L-dopa uptake in renal proximal tubule cells. Am J Physiol Cell Physiol 295:C1602-C1609
16. Chen DR, Chien SY, Kuo SJ, Teng YH, Tsai HT, Kuo JH, Chung JG (2010) SLC34A2 as a novel marker for diagnosis and targeted therapy of breast cancer. Anticancer Res 30:4135-4140
17. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA (2002) Mutations of the BRAF gene in human cancer. Nature 417:949-954 (Pubitemid 34716871)
18. De Luca A, Maiello MR, D'Alessio A, Pergameno M, Normanno N (2012) The RAS/RAF/MEK/ERK and the PI3 K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches. Expert Opin Ther Targets 16(Suppl 2):S17-S27
19. DeFronzo RA, Goldberg M, Agus ZS (1976) The effects of glucose and insulin on renal electrolyte transport. J Clin Invest 58:83-90
20. Dermaku-Sopjani M, Sopjani M, Saxena A, Shojaiefard M, Bogatikov E, Alesutan I, Eichenmuller M, Lang F (2011) Downregulation of NaPi-IIa and NaPi-IIb Na-coupled phosphate transporters by coexpression of Klotho. Cell Physiol Biochem 28:251-258
21. Dieter M, Palmada M, Rajamanickam J, Aydin A, Busjahn A, Boehmer C, Luft FC, Lang F (2004) Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. Obes Res 12:862-870 (Pubitemid 41127323)
22. Eisenhardt AE, Olbrich H, Roring M, Janzarik W, Anh TN, Cin H, Remke M, Witt H, Korshunov A, Pfister SM, Omran H, Brummer T (2011) Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma. Int J Cancer 129:2297-2303
23. Feld S, Hirschberg R (1996) Insulin like growth factor I and the kidney. Trends Endocrinol Metab 7:85-93 (Pubitemid 26144498)
24. Ferreira Francisco FA, Pereira e Silva JL, Hochhegger B, Zanetti G, Marchiori E (2013) Pulmonary alveolar microlithiasis. State-of-the-art review. Respir Med 107:1-9
25. Foller M, Kempe DS, Boini KM, Pathare G, Siraskar B, Capuano P, Alesutan I, Sopjani M, Stange G, Mohebbi N, Bhandaru M, Ackermann TF, Judenhofer MS, Pichler BJ, Biber J, Wagner CA, Lang F (2011) PKB/SGK-resistant GSK3 enhances phosphaturia and calciuria. J Am Soc Nephrol 22:873-880
26. Green CJ, Goransson O, Kular GS, Leslie NR, Gray A, Alessi DR, Sakamoto K, Hundal HS (2008) Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake. J Biol Chem 283:27653-27667
27. Henrion U, Zumhagen S, Steinke K, Strutz-Seebohm N, Stallmeyer B, Lang F, Schulze-Bahr E, Seebohm G (2012) Overlapping cardiac phenotype associated with a familial mutation in the voltage sensor of the KCNQ1 channel. Cell Physiol Biochem 29:809-818
28. Hilfiker H, Hattenhauer O, Traebert M, Forster I, Murer H, Biber J (1998) Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine. Proc Natl Acad Sci USA 95:14564-14569 (Pubitemid 28549407)
29. Hosseinzadeh Z, Bhavsar SK, Lang F (2012a) Down-regulation of the myoinositol transporter SMIT by JAK2. Cell Physiol Biochem 30:1473-1480
30. Hosseinzadeh Z, Bhavsar SK, Lang F (2012b) Downregulation of ClC-2 by JAK2. Cell Physiol Biochem 29:737-742
31. Hosseinzadeh Z, Dong L, Bhavsar SK, Warsi J, Almilaji A, Lang F (2013a) Upregulation of peptide transporters PEPT1 and PEPT2 by Janus kinase JAK2. Cell Physiol Biochem 31:673-682
32. Hosseinzadeh Z, Sopjani M, Pakladok T, Bhavsar SK, Lang F (2013b) Downregulation of KCNQ4 by Janus kinase 2. J Membr Biol 246:335-341
33. Hu MC, Shi M, Zhang J, Pastor J, Nakatani T, Lanske B, Razzaque MS, Rosenblatt KP, Baum MG, Kuro-o M, Moe OW (2010) Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J 24:3438-3450
34. Ishiki M, Klip A (2005) Minireview: recent developments in the regulation of glucose transporter-4 traffic: new signals, locations, and partners. Endocrinology 146:5071-5078 (Pubitemid 41653019)
35. Jarzab B, Wiench M, Fujarewicz K, Simek K, Jarzab M, Oczko-Wojciechowska M, Wloch J, Czarniecka A, Chmielik E, Lange D, Pawlaczek A, Szpak S, Gubala E, Swierniak A (2005) Gene expression profile of papillary thyroid cancer: sources of variability and diagnostic implications. Cancer Res 65:1587-1597 (Pubitemid 40270189)
36. Jehle AW, Forgo J, Biber J, Lederer E, Krapf R, Murer H (1998) IGF-I and vanadate stimulate Na/Pi-cotransport in OK cells by increasing type II Na/Pi-cotransporter protein stability. Pflugers Arch 437:149-154 (Pubitemid 29071325)
37. Kamata T, Pritchard C (2011) Mechanisms of aneuploidy induction by RAS and RAF oncogenes. Am J Cancer Res 1:955-971
38. Kempe DS, Ackermann TF, Boini KM, Klaus F, Umbach AT, Dermaku-Sopjani M, Judenhofer MS, Pichler BJ, Capuano P, Stange G, Wagner CA, Birnbaum MJ, Pearce D, Foller M, Lang F (2010a) Akt2/PKBbeta-sensitive regulation of renal phosphate transport. Acta Physiol (Oxf) 200:75-85
39. Kempe DS, Dermaku-Sopjani M, Frohlich H, Sopjani M, Umbach A, Puchchakayala G, Capasso A, Weiss F, Stubs M, Foller M, Lang F (2010b) Rapamycin-induced phosphaturia. Nephrol Dial Transplant 25:2938-2944
40. Lee IH, Dinudom A, Sanchez-Perez A, Kumar S, Cook DI (2007) Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2. J Biol Chem 282:29866-29873 (Pubitemid 350035273)
41. Lim SK, Park MJ, Jung HK, Park AY, Kim DI, Kim JC, Bae CS, Kim KY, Yoon KC, Han HJ, Park SH (2008) Bradykinin stimulates glutamate uptake via both B1R and B2R activation in a human retinal pigment epithelial cells. Life Sci 83:761-770
42. Mannack G, Graf D, Donner MM, Richter L, Gorg B, Vom Dahl S, Haussinger D, Schliess F (2008) Taurolithocholic acid-3 sulfate impairs insulin signaling in cultured rat hepatocytes and perfused rat liver. Cell Physiol Biochem 21:137-150
43. Marks J, Debnam ES, Unwin RJ (2010) Phosphate homeostasis and the renal-gastrointestinal axis. Am J Physiol Renal Physiol 299:F285-F296
44. Mia S, Munoz C, Pakladok T, Siraskar G, Voelkl J, Alesutan I, Lang F (2012) Downregulation of Kv1.5 K channels by the AMP-activated protein kinase. Cell Physiol Biochem 30:1039-1050
45. Munoz C, Almilaji A, Setiawan I, Foller M, Lang F (2013) Upregulation of the inwardly rectifying K(+) channel Kir2.1 (KCNJ2) by protein kinase B (PKB/Akt) and PIKfyve. J Membr Biol 246:189-197
46. Murer H, Hernando N, Forster I, Biber J (2000) Proximal tubular phosphate reabsorption: molecular mechanisms. Physiol Rev 80:1373-1409
47. Murer H, Forster I, Biber J (2004) The sodium phosphate cotransporter family SLC34. Pflugers Arch 447:763-767 (Pubitemid 38241464)
48. Murillo-Cuesta S, Rodriguez-de la Rosa L, Cediel R, Lassaletta L, Varela-Nieto I (2011) The role of insulin-like growth factor-I in the physiopathology of hearing. Front Mol Neurosci 4:11
49. Nielsen LB, Pedersen FS, Pedersen L (2001) Expression of type III sodium-dependent phosphate transporters/retroviral receptors mRNAs during osteoblast differentiation. Bone 28:160-166 (Pubitemid 32143684)
50. Nowik M, Picard N, Stange G, Capuano P, Tenenhouse HS, Biber J, Murer H, Wagner CA (2008) Renal phosphaturia during metabolic acidosis revisited: molecular mechanisms for decreased renal phosphate reabsorption. Pflugers Arch 457:539-549
51. Pakladok T, Hosseinzadeh Z, Alesutan I, Lang F (2012) Stimulation of the Na(+)-coupled glucose transporter SGLT1 by B-RAF. Biochem Biophys Res Commun 427:689-693
52. Pakladok T, Almilaji A, Munoz C, Alesutan I, Lang F (2013) PIKfyve sensitivity of hERG channels. Cell Physiol Biochem 31:785-794
53. Parkin DM, Bray F (2006) Chapter 2: the burden of HPV-related cancers. Vaccine 24(Suppl 3:S3):11-25
54. Rangel LB, Sherman-Baust CA, Wernyj RP, Schwartz DR, Cho KR, Morin PJ (2003) Characterization of novel human ovarian cancer-specific transcripts (HOSTs) identified by serial analysis of gene expression. Oncogene 22:7225-7232 (Pubitemid 37378555)
55. Roring M, Brummer T (2012) Aberrant B-Raf signaling in human cancer - 10 years from bench to bedside. Crit Rev Oncog 17:97-121
56. Shojaiefard M, Hosseinzadeh Z, Bhavsar SK, Lang F (2012) Downregulation of the creatine transporter SLC6A8 by JAK2. J Membr Biol 245:157-163
57. Strutz-Seebohm N, Pusch M, Wolf S, Stoll R, Tapken D, Gerwert K, Attali B, Seebohm G (2011) Structural basis of slow activation gating in the cardiac I Ks channel complex. Cell Physiol Biochem 27:443-452
58. Tanner S, Shen Z, Ng J, Florea L, Guigo R, Briggs SP, Bafna V (2007) Improving gene annotation using peptide mass spectrometry. Genome Res 17:231-239 (Pubitemid 46220768)
59. Vaughan-Jones RD, Swietach P (2008) Pushing and pulling the cardiac sodium/hydrogen exchanger. Circ Res 103:773-775
60. Villa-Bellosta R, Ravera S, Sorribas V, Stange G, Levi M, Murer H, Biber J, Forster IC (2009) The Na+ -Pi cotransporter PiT-2 (SLC20A2) is expressed in the apical membrane of rat renal proximal tubules and regulated by dietary Pi. Am J Physiol Renal Physiol 296:F691-F699
61. Wallace DP (2011) Cyclic AMP-mediated cyst expansion. Biochim Biophys Acta 1812:1291-1300
62. Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R, Cancer Genome Project (2004) Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 116:855-867 (Pubitemid 38410730)
63. Warsi J, Hosseinzadeh Z, Dong L, Pakladok T, Umbach AT, Bhavsar SK, Shumilina E, Lang F (2013) Effect of Janus kinase 3 on the peptide Transporters PEPT1 and PEPT2. J Membr Biol 246:885-892
64. Whiteman EL, Cho H, Birnbaum MJ (2002) Role of Akt/protein kinase B in metabolism. Trends Endocrinol Metab 13:444-451 (Pubitemid 36733939)
65. Xu H, Inouye M, Hines ER, Collins JF, Ghishan FK (2003) Transcriptional regulation of the human NaPi-IIb cotransporter by EGF in Caco-2 cells involves c-myb. Am J Physiol Cell Physiol 284:C1262-C1271 (Pubitemid 36457407)