-
1
-
-
34648815009
-
Lung cancer in never smokers-a different disease
-
Sun S., Schiller J.H., Gazdar A.F. Lung cancer in never smokers-a different disease. Nat Rev Cancer 2007, 7:778-790.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 778-790
-
-
Sun, S.1
Schiller, J.H.2
Gazdar, A.F.3
-
3
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-lable, randomised, phase 3 study
-
Zhou C., Wu Y.L., Chen G., Feng J., Liu X.Q., Wang C., et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-lable, randomised, phase 3 study. Lancet Oncol 2011, 12:735-742.
-
(2011)
Lancet Oncol
, vol.12
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
Feng, J.4
Liu, X.Q.5
Wang, C.6
-
4
-
-
68149105809
-
Clinical efficacy of erlotinib in patients previously treated for advanced non-small cell lung cancer
-
Zhou S., Ren S., Yan L., Zhang L., Tang L., Zhang J., et al. Clinical efficacy of erlotinib in patients previously treated for advanced non-small cell lung cancer. Respirology 2009, 14:709-715.
-
(2009)
Respirology
, vol.14
, pp. 709-715
-
-
Zhou, S.1
Ren, S.2
Yan, L.3
Zhang, L.4
Tang, L.5
Zhang, J.6
-
5
-
-
84867743860
-
Analysis of driver mutations in female non-smoker Asian patients with pulmonary adenocarcinoma
-
Ren S., Kuang P., Zheng L., Su C., Li J., Li B., et al. Analysis of driver mutations in female non-smoker Asian patients with pulmonary adenocarcinoma. Cell Biochem Biophys 2012, 64:155-160.
-
(2012)
Cell Biochem Biophys
, vol.64
, pp. 155-160
-
-
Ren, S.1
Kuang, P.2
Zheng, L.3
Su, C.4
Li, J.5
Li, B.6
-
6
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S., Boggon T.J., Dayaram T., Janne P.A., Kocher O., Meyerson M., et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005, 352:786-792.
-
(2005)
N Engl J Med
, vol.352
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
Janne, P.A.4
Kocher, O.5
Meyerson, M.6
-
7
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman J.A., Zejnullahu K., Mitsudomi T., Song Y., Hyland C., Park J.O., et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 2007, 316:1039-1043.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
-
8
-
-
17444419037
-
Wnt signaling in lung cancer
-
Mazieres J., He B., You L., Xu Z., Jablons D.M. Wnt signaling in lung cancer. Cancer Lett 2005, 222:1-10.
-
(2005)
Cancer Lett
, vol.222
, pp. 1-10
-
-
Mazieres, J.1
He, B.2
You, L.3
Xu, Z.4
Jablons, D.M.5
-
9
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000, 14:1837-1851.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
10
-
-
67349139181
-
Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma
-
Akiri G., Cherian M.M., Vijayakumar S., Liu G., Bafico A., Aaronson S.A. Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma. Oncogene 2009, 28:2163-2172.
-
(2009)
Oncogene
, vol.28
, pp. 2163-2172
-
-
Akiri, G.1
Cherian, M.M.2
Vijayakumar, S.3
Liu, G.4
Bafico, A.5
Aaronson, S.A.6
-
11
-
-
35948990450
-
Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer
-
Suzuki M., Shigematsu H., Nakajima T., Kubo R., Motohashi S., Sekine Y., et al. Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer. Clin Cancer Res 2007, 13:6087-6092.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6087-6092
-
-
Suzuki, M.1
Shigematsu, H.2
Nakajima, T.3
Kubo, R.4
Motohashi, S.5
Sekine, Y.6
-
12
-
-
79960861074
-
β-catenin/Tcf-4 complex transcriptional regulates AKT1 in glioma
-
Chen L., Huang K., Han L., Shi Z., Zhang K., Pu P., et al. β-catenin/Tcf-4 complex transcriptional regulates AKT1 in glioma. Int J Oncol 2011, 39:883-890.
-
(2011)
Int J Oncol
, vol.39
, pp. 883-890
-
-
Chen, L.1
Huang, K.2
Han, L.3
Shi, Z.4
Zhang, K.5
Pu, P.6
-
13
-
-
22044454824
-
EGFR mutation conferring primary resistance to gefitinib in non-small-cell lung cancer
-
Shih J.Y., Gow C.H., Yang P.C. EGFR mutation conferring primary resistance to gefitinib in non-small-cell lung cancer. N Engl J Med 2005, 353:207-208.
-
(2005)
N Engl J Med
, vol.353
, pp. 207-208
-
-
Shih, J.Y.1
Gow, C.H.2
Yang, P.C.3
-
14
-
-
4444332925
-
AKT phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer
-
Cappuzzo F., Magrini E., Ceresoli G.L., Bartolini S., Rossi E., Ludovini V., et al. AKT phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2004, 96:1134-1141.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1134-1141
-
-
Cappuzzo, F.1
Magrini, E.2
Ceresoli, G.L.3
Bartolini, S.4
Rossi, E.5
Ludovini, V.6
-
15
-
-
84855439199
-
Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome gefitinib-resistance in non-small cell lung cancer cell lines
-
Li H., Schmid-Bindert G., Wang D., Zhao Y., Yang X., Su B., et al. Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome gefitinib-resistance in non-small cell lung cancer cell lines. Adv Med Sci 2011, 56:275-284.
-
(2011)
Adv Med Sci
, vol.56
, pp. 275-284
-
-
Li, H.1
Schmid-Bindert, G.2
Wang, D.3
Zhao, Y.4
Yang, X.5
Su, B.6
-
16
-
-
84860491093
-
Role of Wnt/β-catenin signaling in drug resistance of pancreatic cancer
-
Cui J., Jiang W., Wang S., Wang L., Xie K. Role of Wnt/β-catenin signaling in drug resistance of pancreatic cancer. Curr Pharm Des 2012, 18:2464-2471.
-
(2012)
Curr Pharm Des
, vol.18
, pp. 2464-2471
-
-
Cui, J.1
Jiang, W.2
Wang, S.3
Wang, L.4
Xie, K.5
-
17
-
-
34548831213
-
The biology of cancer stem cells
-
Lobo N.A., Shimono Y., Qian D., Clarke M.F. The biology of cancer stem cells. Annu Rev Cell Dev Biol 2007, 23:675-699.
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 675-699
-
-
Lobo, N.A.1
Shimono, Y.2
Qian, D.3
Clarke, M.F.4
-
18
-
-
20644433937
-
Establishment of a human non-small cell lung cancer cell line resistance to gefitinib
-
Keizumi F., Shimoyama T., Taguchi F., Saijo N., Nishio K. Establishment of a human non-small cell lung cancer cell line resistance to gefitinib. Int J Cancer 2005, 116:36-44.
-
(2005)
Int J Cancer
, vol.116
, pp. 36-44
-
-
Keizumi, F.1
Shimoyama, T.2
Taguchi, F.3
Saijo, N.4
Nishio, K.5
-
19
-
-
78649762711
-
Integrin beta1 over-expression associates with resistance to tyrosine kinase inhibitor gefitinib in non-small cell lung cancer
-
Ju L., Zhou C., Li W., Yan L. Integrin beta1 over-expression associates with resistance to tyrosine kinase inhibitor gefitinib in non-small cell lung cancer. J Cell Biochem 2010, 111:1565-1574.
-
(2010)
J Cell Biochem
, vol.111
, pp. 1565-1574
-
-
Ju, L.1
Zhou, C.2
Li, W.3
Yan, L.4
-
20
-
-
0037155691
-
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
-
Liu C., Li Y., Semenov M., Han C., Baeg G.H., Tan Y., et al. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 2002, 108:837-847.
-
(2002)
Cell
, vol.108
, pp. 837-847
-
-
Liu, C.1
Li, Y.2
Semenov, M.3
Han, C.4
Baeg, G.H.5
Tan, Y.6
-
21
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
-
Behrens J., Jerchow B.A., Wurtele M. Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science 1998, 280:596-599.
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Wurtele, M.3
-
22
-
-
0033387207
-
Beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma
-
Kondo Y., Kanai Y., Sakamoto M., Genda T., Mizokami M., Uede R., et al. Beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma. Jpn J Cancer Res 1999, 90:1301-1309.
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 1301-1309
-
-
Kondo, Y.1
Kanai, Y.2
Sakamoto, M.3
Genda, T.4
Mizokami, M.5
Uede, R.6
-
23
-
-
84874984968
-
Alteration of the E-cadherin/β-catenin complex is an independent poor prognostic factor in lung adenocarcinoma
-
Kim H., Yoo S.B., Sun P., Jin Y., Jheon S., Lee C.T., et al. Alteration of the E-cadherin/β-catenin complex is an independent poor prognostic factor in lung adenocarcinoma. Korean J Pathol 2013, 47:44-51.
-
(2013)
Korean J Pathol
, vol.47
, pp. 44-51
-
-
Kim, H.1
Yoo, S.B.2
Sun, P.3
Jin, Y.4
Jheon, S.5
Lee, C.T.6
-
24
-
-
84872617436
-
WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells
-
Yuan G., Regel I., Lian F., Friedrich T., Hitkove I., Hofheinz R.D., et al. WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells. Oncogene 2013, 32:375-387.
-
(2013)
Oncogene
, vol.32
, pp. 375-387
-
-
Yuan, G.1
Regel, I.2
Lian, F.3
Friedrich, T.4
Hitkove, I.5
Hofheinz, R.D.6
-
25
-
-
81855217368
-
Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy
-
Kendziorra E., Ahlborn K., Spitzner M., Rave-Fränk M., Emons G., Gaedcke J., et al. Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy. Carcinogenesis 2011, 32:1824-1831.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1824-1831
-
-
Kendziorra, E.1
Ahlborn, K.2
Spitzner, M.3
Rave-Fränk, M.4
Emons, G.5
Gaedcke, J.6
-
26
-
-
84866672444
-
Targeted inhibition of TCF activity promotes syndecan-2 expression and sensitization to doxorubicin in osteosarcoma cells and bone tumors in mice
-
Dieudonné F.X., Marion A., Marie P.J., Modrowski D. Targeted inhibition of TCF activity promotes syndecan-2 expression and sensitization to doxorubicin in osteosarcoma cells and bone tumors in mice. J Bone Miner Res 2012, 27:2118-2129.
-
(2012)
J Bone Miner Res
, vol.27
, pp. 2118-2129
-
-
Dieudonné, F.X.1
Marion, A.2
Marie, P.J.3
Modrowski, D.4
-
27
-
-
84859523707
-
Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML
-
Heidel F.H., Bullinger L., Feng Z., Wang Z., Neff T.A., Stein L., et al. Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML. Cell Stem Cell 2012, 10:412-424.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 412-424
-
-
Heidel, F.H.1
Bullinger, L.2
Feng, Z.3
Wang, Z.4
Neff, T.A.5
Stein, L.6
-
28
-
-
84892793574
-
Alteration of the E-cadherin/β-catenin complex predicts poor response to epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment
-
[in press]
-
Yoo S.B., Kim Y.J., Kim H., Jin Y., Sun P.L., Jheon S., et al. Alteration of the E-cadherin/β-catenin complex predicts poor response to epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment. Ann Surg Oncol 2013, [in press].
-
(2013)
Ann Surg Oncol
-
-
Yoo, S.B.1
Kim, Y.J.2
Kim, H.3
Jin, Y.4
Sun, P.L.5
Jheon, S.6
-
29
-
-
33846138978
-
Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells
-
Faivre E.J., Lange C.A. Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells. Mol Cell Biol 2007, 27:466-480.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 466-480
-
-
Faivre, E.J.1
Lange, C.A.2
-
30
-
-
34347231979
-
Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin
-
Jeon S.H., Yoon J.Y., Park Y.N., Jeong W.J., Kim S., Jho E.H., et al. Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin. J Biol Chem 2007, 282:14482-14492.
-
(2007)
J Biol Chem
, vol.282
, pp. 14482-14492
-
-
Jeon, S.H.1
Yoon, J.Y.2
Park, Y.N.3
Jeong, W.J.4
Kim, S.5
Jho, E.H.6
-
31
-
-
79251611366
-
Interruption of β-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells
-
Yue X., Lan F., Yang W., Yang Y., Han L., Zhang A., et al. Interruption of β-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells. Brain Res 2010, 1366:27-37.
-
(2010)
Brain Res
, vol.1366
, pp. 27-37
-
-
Yue, X.1
Lan, F.2
Yang, W.3
Yang, Y.4
Han, L.5
Zhang, A.6
|