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Volumn 1366, Issue , 2010, Pages 27-37

Interruption of β-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells

Author keywords

AKT; AKT protein family, which members are also called protein kinases B; EGFR; epidermal growth factor receptor; matrix metalloproteinase 2; matrix metalloproteinase 9; MMP2; MMP9; signal transducer and activator of transcription 3; STAT3; Vascular endothelial growth factor; VEGF

Indexed keywords

BETA CATENIN; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE A; GELATINASE B; PROTEIN KINASE B; SMALL INTERFERING RNA; STAT3 PROTEIN;

EID: 79251611366     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.10.032     Document Type: Article
Times cited : (92)

References (39)
  • 1
    • 70350515157 scopus 로고    scopus 로고
    • Cancer Genome Atlas Research NetworkComprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Atlas CG; Cancer Genome Atlas Research Network Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature 455 2008 1061 1068
    • (2008) Nature , vol.455 , pp. 1061-1068
    • Atlas, C.G.1
  • 2
    • 77149174855 scopus 로고    scopus 로고
    • Wnt signaling from development to disease: Insights from model systems
    • K.M. Cadigan, and M. Peifer Wnt signaling from development to disease: insights from model systems Cold Spring Harb Perspect Biol. 1 2009 a002881
    • (2009) Cold Spring Harb Perspect Biol. , vol.1 , pp. 002881
    • Cadigan, K.M.1    Peifer, M.2
  • 3
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • H. Clevers Wnt/beta-catenin signaling in development and disease Cell 127 2006 469 480
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 4
    • 17244380380 scopus 로고    scopus 로고
    • A survey of current work in biomedical text mining
    • A.M. Cohen, and W.R. Hersh A survey of current work in biomedical text mining Brief. Bioinform. 6 2005 57 71
    • (2005) Brief. Bioinform. , vol.6 , pp. 57-71
    • Cohen, A.M.1    Hersh, W.R.2
  • 5
    • 39749167037 scopus 로고    scopus 로고
    • Promising new therapies for malignant gliomas
    • H.A. Fine Promising new therapies for malignant gliomas Cancer J. 13 2007 349 354
    • (2007) Cancer J. , vol.13 , pp. 349-354
    • Fine, H.A.1
  • 6
    • 0035236048 scopus 로고    scopus 로고
    • GENIES: A natural-language processing system for the extraction of molecular pathways from journal articles
    • C. Friedman, P. Kra, H. Yu, M. Krauthammer, and A. Rzhetsky GENIES: a natural-language processing system for the extraction of molecular pathways from journal articles Bioinformatics 17 Suppl 1 2001 S74 S82
    • (2001) Bioinformatics , vol.17 , Issue.SUPPL. 1
    • Friedman, C.1    Kra, P.2    Yu, H.3    Krauthammer, M.4    Rzhetsky, A.5
  • 8
    • 0038179723 scopus 로고    scopus 로고
    • Cost of migration: Invasion of malignant gliomas and implications for treatment
    • A. Giese, R. Bjerkvig, M.E. Berens, and M. Westphal Cost of migration: invasion of malignant gliomas and implications for treatment J. Clin. Oncol. 21 2003 1624 1636
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1624-1636
    • Giese, A.1    Bjerkvig, R.2    Berens, M.E.3    Westphal, M.4
  • 9
    • 77956915349 scopus 로고    scopus 로고
    • Combination gene therapy with PTEN and EGFR siRNA suppresses U251 malignant glioma cell growth in vitro and in vivo
    • L. Han, A.L. Zhang, P. Xu, X. Yue, Y. Yang, G.X. Wang, Z.F. Jia, P.Y. Pu, and C.S. Kang Combination gene therapy with PTEN and EGFR siRNA suppresses U251 malignant glioma cell growth in vitro and in vivo Med Oncol. PMID 2009 : 19728186.
    • (2009) Med Oncol. PMID
    • Han, L.1    Zhang, A.L.2    Xu, P.3    Yue, X.4    Yang, Y.5    Wang, G.X.6    Jia, Z.F.7    Pu, P.Y.8    Kang, C.S.9
  • 11
    • 73949083511 scopus 로고    scopus 로고
    • Oncogenic EGFR signaling networks in glioma
    • P.H. Huang, A.M. Xu, and F.M. White Oncogenic EGFR signaling networks in glioma Sci. Signal. 2 2009 re6
    • (2009) Sci. Signal. , vol.2 , pp. 6
    • Huang, P.H.1    Xu, A.M.2    White, F.M.3
  • 12
    • 36248992406 scopus 로고    scopus 로고
    • Growth factors of the EGF family and their receptors
    • P. Hubert Growth factors of the EGF family and their receptors Bull. Cancer 94 2007 F137 F145
    • (2007) Bull. Cancer , vol.94
    • Hubert, P.1
  • 13
    • 63749086305 scopus 로고    scopus 로고
    • ErbB receptors and signaling pathways in cancer
    • N.E. Hynes, and G. MacDonald ErbB receptors and signaling pathways in cancer Curr. Opin. Cell Biol. 21 2009 177 184
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 177-184
    • Hynes, N.E.1    MacDonald, G.2
  • 14
    • 70449657727 scopus 로고    scopus 로고
    • EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin
    • H. Ji, J. Wang, H. Nika, D. Hawke, S. Keezer, Q. Ge, B. Fang, X. Fang, D. Fang, D.W. Litchfield, K. Aldape, and Z. Lu EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin Mol. Cell 36 2009 547 559
    • (2009) Mol. Cell , vol.36 , pp. 547-559
    • Ji, H.1    Wang, J.2    Nika, H.3    Hawke, D.4    Keezer, S.5    Ge, Q.6    Fang, B.7    Fang, X.8    Fang, D.9    Litchfield, D.W.10    Aldape, K.11    Lu, Z.12
  • 15
  • 16
    • 67651154339 scopus 로고    scopus 로고
    • Therapeutic inhibition of the epidermal growth factor receptor in high-grade gliomas: Where do we stand?
    • G. Karpel-Massler, U. Schmidt, A. Unterberg, and M.E. Halatsch Therapeutic inhibition of the epidermal growth factor receptor in high-grade gliomas: where do we stand? Mol. Cancer Res. 7 2009 1000 1012
    • (2009) Mol. Cancer Res. , vol.7 , pp. 1000-1012
    • Karpel-Massler, G.1    Schmidt, U.2    Unterberg, A.3    Halatsch, M.E.4
  • 17
    • 77952302757 scopus 로고    scopus 로고
    • Epidermal growth factor receptor regulates beta-catenin location, stability, and transcriptional activity in oral cancer
    • C.H. Lee, H.W. Hung, P.H. Hung, and Y.S. Shieh Epidermal growth factor receptor regulates beta-catenin location, stability, and transcriptional activity in oral cancer Mol. Cancer 9 2010 64
    • (2010) Mol. Cancer , vol.9 , pp. 64
    • Lee, C.H.1    Hung, H.W.2    Hung, P.H.3    Shieh, Y.S.4
  • 18
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • B.T. MacDonald, K. Tamai, and X. He Wnt/beta-catenin signaling: components, mechanisms, and diseases Dev. Cell 17 2009 9 26
    • (2009) Dev. Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 19
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • W.J. Nelson, and R. Nusse Convergence of Wnt, beta-catenin, and cadherin pathways Science 303 2004 1483 1487
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 20
    • 19644373254 scopus 로고    scopus 로고
    • Wnt signaling in disease and in development
    • R. Nusse Wnt signaling in disease and in development Cell Res. 15 2005 28 32
    • (2005) Cell Res. , vol.15 , pp. 28-32
    • Nusse, R.1
  • 21
    • 71149111905 scopus 로고    scopus 로고
    • Wnt signaling and the polarity of the primary body axis
    • C.P. Petersen, and P.W. Reddien Wnt signaling and the polarity of the primary body axis Cell 139 2009 1056 1068
    • (2009) Cell , vol.139 , pp. 1056-1068
    • Petersen, C.P.1    Reddien, P.W.2
  • 22
    • 33745420305 scopus 로고    scopus 로고
    • Downregulation of PIK3CB by siRNA suppresses malignant glioma cell growth in vitro and in vivo
    • P. Pu, C. Kang, Z. Zhang, X. Liu, and H. Jiang Down-regulation of PIK3CB by siRNA suppresses malignant glioma cell growth in vitro and in vivo Technol. Cancer Res. Treat. 5 2006 271 280 (Pubitemid 43946260)
    • (2006) Technology in Cancer Research and Treatment , vol.5 , Issue.3 , pp. 271-280
    • Pu, P.1    Kang, C.2    Zhang, Z.3    Liu, X.4    Jiang, H.5
  • 23
    • 62549151288 scopus 로고    scopus 로고
    • Down-regulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth
    • P. Pu, Z. Zhang, C. Kang, R. Jiang, Z. Jia, G. Wang, and H. Jiang Down-regulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth Cancer Gene Ther. 16 2009 351 361
    • (2009) Cancer Gene Ther. , vol.16 , pp. 351-361
    • Pu, P.1    Zhang, Z.2    Kang, C.3    Jiang, R.4    Jia, Z.5    Wang, G.6    Jiang, H.7
  • 24
    • 59349097033 scopus 로고    scopus 로고
    • EGFR-dependent migration of glial cells is mediated by reorganisation of N-cadherin
    • A. Rappl, G. Piontek, and J. Schlegel EGFR-dependent migration of glial cells is mediated by reorganisation of N-cadherin J. Cell Sci. 121 2008 4089 4097
    • (2008) J. Cell Sci. , vol.121 , pp. 4089-4097
    • Rappl, A.1    Piontek, G.2    Schlegel, J.3
  • 26
  • 27
    • 0002284942 scopus 로고    scopus 로고
    • Identifying the interaction between genes and gene products based on frequently seen verbs in MEDLINE abstracts
    • T. Sekimizu, H.S. Park, and J. Tsujii Identifying the interaction between genes and gene products based on frequently seen verbs in MEDLINE abstracts Genome. Inf. Ser. Workshop. Genome. Inform. 9 1998 62 71
    • (1998) Genome. Inf. Ser. Workshop. Genome. Inform. , vol.9 , pp. 62-71
    • Sekimizu, T.1    Park, H.S.2    Tsujii, J.3
  • 28
    • 34548658287 scopus 로고    scopus 로고
    • PepBank-a database of peptides based on sequence text mining and public peptide data sources
    • T. Shtatland, D. Guettler, M. Kossodo, M. Pivovarov, and R. Weissleder PepBank-a database of peptides based on sequence text mining and public peptide data sources BMC Bioinform. 8 2007 280
    • (2007) BMC Bioinform. , vol.8 , pp. 280
    • Shtatland, T.1    Guettler, D.2    Kossodo, M.3    Pivovarov, M.4    Weissleder, R.5
  • 29
    • 0036358850 scopus 로고    scopus 로고
    • Predicting the sub-cellular location of proteins from text using support vector machines
    • B.J. Stapley, L.A. Kelley, and M.J. Sternberg Predicting the sub-cellular location of proteins from text using support vector machines Pac. Symp. Biocomput. 2002 374 385
    • (2002) Pac. Symp. Biocomput. , pp. 374-385
    • Stapley, B.J.1    Kelley, L.A.2    Sternberg, M.J.3
  • 33
    • 36249029788 scopus 로고    scopus 로고
    • Pathway-based approaches for analysis of genomewide association studies
    • K. Wang, M. Li, and M. Bucan Pathway-based approaches for analysis of genomewide association studies Am. J. Hum. Genet. 81 2007 PMID: 17966091.
    • (2007) Am. J. Hum. Genet. , vol.81
    • Wang, K.1    Li, M.2    Bucan, M.3
  • 34
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • P.Y. Wen, and S. Kesari Malignant gliomas in adults N Engl J. Med. 359 2008 492 507
    • (2008) N Engl J. Med. , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 35
    • 70449720821 scopus 로고    scopus 로고
    • Text mining and manual curation of chemical-gene-disease networks for the comparative toxicogenomics database (CTD)
    • T.C. Wiegers, A.P. Davis, K.B. Cohen, L. Hirschman, and C.J. Mattingly Text mining and manual curation of chemical-gene-disease networks for the comparative toxicogenomics database (CTD) BMC Bioinform. 10 2009 326
    • (2009) BMC Bioinform. , vol.10 , pp. 326
    • Wiegers, T.C.1    Davis, A.P.2    Cohen, K.B.3    Hirschman, L.4    Mattingly, C.J.5
  • 36
    • 33744791463 scopus 로고    scopus 로고
    • Wnt signaling: Is the party in the nucleus?
    • K. Willert, and K.A. Jones Wnt signaling: is the party in the nucleus? Genes Dev. 20 2006 1394 1404
    • (2006) Genes Dev. , vol.20 , pp. 1394-1404
    • Willert, K.1    Jones, K.A.2
  • 39
    • 34247623628 scopus 로고    scopus 로고
    • Getting connected: Analysis and principles of biological networks
    • X. Zhu, M. Gerstein, and M. Snyder Getting connected: analysis and principles of biological networks Genes Dev. 21 2007 1010 1024
    • (2007) Genes Dev. , vol.21 , pp. 1010-1024
    • Zhu, X.1    Gerstein, M.2    Snyder, M.3


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