메뉴 건너뛰기




Volumn 20, Issue 6, 2014, Pages 526-537

Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells

Author keywords

Germline; Niche growth factor; Oxygen tension; Self renewal; Tissue specific stem cells

Indexed keywords

ALKALINE PHOSPHATASE; COMPLEMENTARY DNA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; OCTAMER TRANSCRIPTION FACTOR 4; SHORT HAIRPIN RNA; SOMATOMEDIN C RECEPTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; MTOR PROTEIN, MOUSE; PHOSPHATIDYLINOSITOL 3 KINASE; POU5F1 PROTEIN, MOUSE; STEM CELL FACTOR RECEPTOR; TARGET OF RAPAMYCIN KINASE;

EID: 84900560561     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gau016     Document Type: Article
Times cited : (17)

References (35)
  • 1
    • 0036153327 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by IGF-I in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2alpha
    • Akeno N, Robins J, Zhang M, Czyzyk-Krzeska MF, Clemens TL. Induction of vascular endothelial growth factor by IGF-I in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2alpha. Endocrinology 2002;143:420-425.
    • (2002) Endocrinology , vol.143 , pp. 420-425
    • Akeno, N.1    Robins, J.2    Zhang, M.3    Czyzyk-Krzeska, M.F.4    Clemens, T.L.5
  • 2
    • 0019170218 scopus 로고
    • Serum-free cell culture: a unifying approach
    • Barnes D, Sato G. Serum-free cell culture: a unifying approach. Cell 1980;22:649-655.
    • (1980) Cell , vol.22 , pp. 649-655
    • Barnes, D.1    Sato, G.2
  • 4
    • 33745685879 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway
    • Carroll VA, Ashcroft M. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway. Cancer Res 2006;66:6264-6270.
    • (2006) Cancer Res , vol.66 , pp. 6264-6270
    • Carroll, V.A.1    Ashcroft, M.2
  • 7
    • 85047692887 scopus 로고    scopus 로고
    • Expansion of human SCID-repopulating cells under hypoxic conditions
    • Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC. Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest 2003;112:126-135.
    • (2003) J Clin Invest , vol.112 , pp. 126-135
    • Danet, G.H.1    Pan, Y.2    Luongo, J.L.3    Bonnet, D.A.4    Simon, M.C.5
  • 8
    • 16344380951 scopus 로고    scopus 로고
    • Low O2 tensions and the prevention of differentiation of hES cells
    • Ezashi T, Das P, Roberts RM. Low O2 tensions and the prevention of differentiation of hES cells. Proc Natl Acad Sci USA 2005;102:4783-4788.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4783-4788
    • Ezashi, T.1    Das, P.2    Roberts, R.M.3
  • 10
    • 42449111722 scopus 로고    scopus 로고
    • PHDs overactivation during chronic hypoxia 'desensitizes' HIF alpha and protects cells from necrosis
    • Ginouvès A, Ilc K, Macías N, Pouysségur J, Berra E. PHDs overactivation during chronic hypoxia 'desensitizes' HIF alpha and protects cells from necrosis. Proc Natl Acad Sci USA 2008;105:4745-4750.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4745-4750
    • Ginouvès, A.1    Ilc, K.2    Macías, N.3    Pouysségur, J.4    Berra, E.5
  • 11
    • 0025147087 scopus 로고
    • Primordial germ cells in the mouse embryo during gastrulation
    • Ginsburg M, Snow MH, McLaren A. Primordial germ cells in the mouse embryo during gastrulation. Development 1990;110:521-528.
    • (1990) Development , vol.110 , pp. 521-528
    • Ginsburg, M.1    Snow, M.H.2    McLaren, A.3
  • 12
    • 33645976805 scopus 로고    scopus 로고
    • New evidence for the origin of intracranial germ cell tumours from primordial germ cells: expression of pluripotency and cell differentiation markers
    • Hoei-Hansen CE, Sehested A, Juhler M, Lau YF, Skakkebaek NE, Laursen H, Rajpert-de Meyts E. New evidence for the origin of intracranial germ cell tumours from primordial germ cells: expression of pluripotency and cell differentiation markers. J Pathol 2006;209:25-33.
    • (2006) J Pathol , vol.209 , pp. 25-33
    • Hoei-Hansen, C.E.1    Sehested, A.2    Juhler, M.3    Lau, Y.F.4    Skakkebaek, N.E.5    Laursen, H.6    Rajpert-de Meyts, E.7
  • 14
  • 15
    • 81755184076 scopus 로고    scopus 로고
    • Metformin represses self-renewal of the human breast carcinoma stem cells via inhibition of estrogen receptor-mediated OCT-4 expression
    • Jung JW, Park SB, Lee SJ, Seo MS, Trosko JE, Kang KS. Metformin represses self-renewal of the human breast carcinoma stem cells via inhibition of estrogen receptor-mediated OCT-4 expression. PLoS One 2011;6:e28068.
    • (2011) PLoS One , vol.6
    • Jung, J.W.1    Park, S.B.2    Lee, S.J.3    Seo, M.S.4    Trosko, J.E.5    Kang, K.S.6
  • 17
    • 34247527730 scopus 로고    scopus 로고
    • Hypoxia-inducible factors, stem cells, and cancer
    • Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007;129:465-472.
    • (2007) Cell , vol.129 , pp. 465-472
    • Keith, B.1    Simon, M.C.2
  • 20
    • 78649631618 scopus 로고    scopus 로고
    • A potential role for insulin-like growth factor signaling in induction of pluripotent stem cell formation
    • Li Y, Geng YJ. A potential role for insulin-like growth factor signaling in induction of pluripotent stem cell formation. Growth Horm IGF Res 2010;20:391-398.
    • (2010) Growth Horm IGF Res , vol.20 , pp. 391-398
    • Li, Y.1    Geng, Y.J.2
  • 23
    • 0034307432 scopus 로고    scopus 로고
    • Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells
    • Morrison SJ, Csete M, Groves AK, Melega W, Wold B, Anderson DJ. Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells. J Neurosci 2000;20:7370-7376.
    • (2000) J Neurosci , vol.20 , pp. 7370-7376
    • Morrison, S.J.1    Csete, M.2    Groves, A.K.3    Melega, W.4    Wold, B.5    Anderson, D.J.6
  • 24
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000;24:372-376.
    • (2000) Nat Genet , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 26
    • 0032170283 scopus 로고    scopus 로고
    • In line with our ancestors: Oct-4 and the mammalian germ
    • Pesce M, Gross MK, Scholer HR. In line with our ancestors: Oct-4 and the mammalian germ. Bioessays 1998;20:722-732.
    • (1998) Bioessays , vol.20 , pp. 722-732
    • Pesce, M.1    Gross, M.K.2    Scholer, H.R.3
  • 27
    • 0037130207 scopus 로고    scopus 로고
    • A molecular reprogramming for the specification of germ cell fate in mice
    • Saitou M, Barton SC, Surani MA. A molecular reprogramming for the specification of germ cell fate in mice. Nature 2002;418:293-300.
    • (2002) Nature , vol.418 , pp. 293-300
    • Saitou, M.1    Barton, S.C.2    Surani, M.A.3
  • 29
    • 0034307725 scopus 로고    scopus 로고
    • Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen
    • Studer L, Csete M, Lee SH, Kabbani N, Walikonis J, Wold B, McKay R. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J Neurosci 2000;20:7377-7383.
    • (2000) J Neurosci , vol.20 , pp. 7377-7383
    • Studer, L.1    Csete, M.2    Lee, S.H.3    Kabbani, N.4    Walikonis, J.5    Wold, B.6    McKay, R.7
  • 30
    • 33646549601 scopus 로고    scopus 로고
    • Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells
    • Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T. Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene 2006;25:2697-2707.
    • (2006) Oncogene , vol.25 , pp. 2697-2707
    • Watanabe, S.1    Umehara, H.2    Murayama, K.3    Okabe, M.4    Kimura, T.5    Nakano, T.6
  • 31
    • 84867125426 scopus 로고    scopus 로고
    • Chemotherapeutic sensitivity of testicular germ cell tumors under hypoxic conditions is negatively regulated by SENP1-controlled sumoylation of OCT-4
    • Wu YC, Ling TY, Lu SH, Kuo HC, Ho HN, Yeh SD, Shen CN, Huang YH. Chemotherapeutic sensitivity of testicular germ cell tumors under hypoxic conditions is negatively regulated by SENP1-controlled sumoylation of OCT-4. Cancer Res 2012;72:4963-4973.
    • (2012) Cancer Res , vol.72 , pp. 4963-4973
    • Wu, Y.C.1    Ling, T.Y.2    Lu, S.H.3    Kuo, H.C.4    Ho, H.N.5    Yeh, S.D.6    Shen, C.N.7    Huang, Y.H.8
  • 32
    • 0034465667 scopus 로고    scopus 로고
    • Requirement of Bmp8b for the generation of primordial germ cells in the mouse
    • Ying Y, Liu XM, Marble A, Lawson KA, Zhao GQ. Requirement of Bmp8b for the generation of primordial germ cells in the mouse. Mol Endocriol 2000;14:1053-1063.
    • (2000) Mol Endocriol , vol.14 , pp. 1053-1063
    • Ying, Y.1    Liu, X.M.2    Marble, A.3    Lawson, K.A.4    Zhao, G.Q.5
  • 33
    • 0034932146 scopus 로고    scopus 로고
    • Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways
    • Ying Y, Qi X, Zhao GQ. Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways. Proc Natl Acad Sci USA 2001;98:7858-7862.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7858-7862
    • Ying, Y.1    Qi, X.2    Zhao, G.Q.3
  • 35
    • 58149104232 scopus 로고    scopus 로고
    • Esrrb activates Oct-4 transcription and sustains self-renewal and pluripotency in embryonic stem cells
    • Zhang X, Zhang J, Wang T, Esteban MA, Pei D. Esrrb activates Oct-4 transcription and sustains self-renewal and pluripotency in embryonic stem cells. J Biol Chem 2008;283:35825-35833.
    • (2008) J Biol Chem , vol.283 , pp. 35825-35833
    • Zhang, X.1    Zhang, J.2    Wang, T.3    Esteban, M.A.4    Pei, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.