Chemotherapeutic sensitivity of testicular germ cell tumors under hypoxic conditions is negatively regulated by SENP1-controlled sumoylation of OCT4

Cancer Research

Volumn 72, Issue 19, 2012, Pages 4963-4973

  Wu, Yu Chih ^d   Ling, Thai Yen ^e   Lu, Shing Hwa ^g,h   Kuo, Hung Chih ^b,i,j   Ho, Hong Nerng ^e,f   Yeh, Shauh Der ^c   Shen, Chia Ning ^b,d,i   Huang, Yen Hua ^a,c  

^a Departments of Medicine   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^f NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^g NATIONAL YANG MING UNIVERSITY   (Taiwan)

^h TAIPEI CITY HOSPITAL   (Taiwan)

ⁱ GENOMICS RESEARCH CENTER   (Taiwan)

^j INSTITUTE OF CELLULAR AND ORGANISMIC BIOLOGY   (Taiwan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CISPLATIN; OCTAMER TRANSCRIPTION FACTOR 4; SUMO 1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER RESISTANCE; CHEMOSENSITIVITY; CONTROLLED STUDY; EMBRYONAL CARCINOMA STEM CELL; GENE OVEREXPRESSION; GERM CELL TUMOR; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SUMOYLATION;

ANIMALS; ANOXIA; ANTINEOPLASTIC AGENTS; BLEOMYCIN; BLOTTING, WESTERN; CELL HYPOXIA; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; ENDOPEPTIDASES; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED NOD; MICE, NUDE; MICE, SCID; MUTATION; NEOPLASMS, GERM CELL AND EMBRYONAL; OCTAMER TRANSCRIPTION FACTOR-3; SUMOYLATION; TESTICULAR NEOPLASMS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84867125426     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0673     Document Type: Article

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