Oct4 is required for primordial germ cell survival

EMBO Reports

Volumn 5, Issue 11, 2004, Pages 1078-1083

  Kehler, James ^a   Tolkunova, Elena ^b   Koschorz, Birgit ^b   Pesce, Maurizio ^c   Gentile, Luca ^d   Boiani, Michele ^a,d   Lomelí, Hilda ^e,f   Nagy, Andras ^f   McLaughlin, K John ^a   Schöler, Hans R ^a,d   Tomilin, Alexey ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c CENTRO CARDIOLOGICO MONZINO   (Italy)

^d MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^e INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^f MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Apoptosis; Conditional gene targeting; Cre IoxP; Oct4 function; Primordial germ cells

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO CELL; EMBRYO DEATH; EMBRYO DEVELOPMENT; GENE FUNCTION; GENE TARGETING; GENETIC ANALYSIS; GERM LINE; GONAD DEVELOPMENT; HOMOZYGOSITY; INNER CELL MASS; MAMMAL CELL; MOUSE; NIDATION; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION;

ALLELES; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL LINEAGE; CELL SURVIVAL; DNA-BINDING PROTEINS; EMBRYO; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC VECTORS; GERM CELLS; HOMOZYGOTE; IN SITU NICK-END LABELING; MALE; MICE; MICE, TRANSGENIC; MODELS, GENETIC; OCTAMER TRANSCRIPTION FACTOR-3; PHENOTYPE; SIGNAL TRANSDUCTION; STEM CELLS; TIME FACTORS; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 10044285191     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400279     Document Type: Article

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