Glutathione attenuates ethanol-induced alveolar macrophage oxidative stress and dysfunction by downregulating NADPH oxidases

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 5, 2014, Pages

  Yeligar, Samantha M ^a,b   Harris, Frank L ^a   Hart, C Michael ^b   Brown, Lou Ann S ^a  

^a CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Alveolar macrophage; Glutathione; Nicotinamide adenine dinucleotide phosphate oxidases; Oxidative stress; Phagocytic function

Indexed keywords

ALCOHOL; DICHLORODIHYDROFLUORESCEIN DIACETATE; DRINKING WATER; GLUTATHIONE; MESSENGER RNA; METHYLCELLULOSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ANTIOXIDANT; CENTRAL DEPRESSANT AGENT; CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; NEUTROPHIL CYTOSOL FACTOR 67K; NEUTROPHIL CYTOSOLIC FACTOR 1; NOX4 PROTEIN, MOUSE; OXIDOREDUCTASE; PHOSPHOPROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; DOWN REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; INTERNALIZATION; KLEBSIELLA PNEUMONIAE; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; WESTERN BLOTTING; ALCOHOLISM; ANIMAL; C57BL MOUSE; CELL LINE; DRUG EFFECT; ENZYME ACTIVATION; IMMUNOLOGY; KLEBSIELLA INFECTION; METABOLISM; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASES; PHAGOCYTIC FUNCTION;

ALVEOLAR MACROPHAGE; GLUTATHIONE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASES; OXIDATIVE STRESS; PHAGOCYTIC FUNCTION;

ALCOHOLISM; ANIMALS; ANTIOXIDANTS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DOWN-REGULATION; ENZYME ACTIVATION; ETHANOL; GLUTATHIONE; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MACROPHAGES, ALVEOLAR; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NADH, NADPH OXIDOREDUCTASES; NADPH OXIDASE; OXIDATIVE STRESS; PHOSPHOPROTEINS;

EID: 84900542676     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00159.2013     Document Type: Article

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