Glutathione availability modulates alveolar macrophage function in the chronic ethanol-fed rat

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 4, 2007, Pages

  Brown, Lou Ann S ^a   Ping, Xiao Du ^a   Harris, Frank L ^a   Gauthier, Theresa W ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antioxidants; Apoptosis; Lung; Oxidative stress

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; ACETYLCYSTEINE; ALCOHOL; GLUTATHIONE;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; HOMEOSTASIS; LUNG ALVEOLUS MACROPHAGE; LUNG DISEASE; LUNG FUNCTION; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; STAPHYLOCOCCUS AUREUS;

ALCOHOLISM; ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; GLUTATHIONE; HOMEOSTASIS; IN SITU NICK-END LABELING; MACROPHAGES, ALVEOLAR; MALE; MICROSCOPY, CONFOCAL; OXIDATIVE STRESS; PHAGOCYTOSIS; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 34247252943     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00346.2006     Document Type: Article

References (35)

1. 3H-labeled L-ascorbic acid in human scurvy. Am J Clin Nutr 24: 444-454, 1971.
2. Baker R, Jerrells T. Recent developments in alcoholism: immunological aspects. Recent Dev Alcohol 11: 249-271, 1993.
3. Baughman R, Roselle G. Surfactant deficiency with decreased opsonic activity in a guinea pig model of alcoholism. Alcohol Clin Exp Res 11: 261-264, 1987.
4. Brown L, Harris F, Bechara R, Guidot D. Effect of chronic ethanol ingestion on alveolar type II cell glutathione and inflammatory mediator-induced apoptosis. Alcohol Clin Exp Res 25: 1078-1085, 2001.
5. Brown L, Harris F, Guidot D. Chronic ethanol ingestion potentiates TNF-α-mediated oxidative stress and apoptosis in rat type II cells. Am J Physiol Lung Cell Mol Physiol 281: L377-L386, 2001.
6. Carbone DL, Doorn JA, Kiebler Z, Petersen DR. Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase. Chem Res Toxicol 18: 1324-1331, 2005.
7. D'Souza NB, Nelson S, Summer WR, Deaciuc IV. Alcohol modulates alveolar macrophage tumor necrosis factor-α, superoxide anion, and nitric oxide secretion in the rat. Alcohol Clin Exp Res 20: 156-163, 1996.
8. Forman H, Skelton D. Protection of alveolar macrophages from hyperoxia by γ-glutamyl transpeptidase. Am J Physiol Lung Cell Mol Physiol 259: L102-L107, 1990.
9. Gauthier TW, Ping XD, Harris FL, Wong M, Elbahesh H, Brown LA. Fetal alcohol exposure impairs alveolar macrophage function via decreased glutathione availability. Pediatr Res 57: 76-81, 2005.
10. Greenberg S, Zhao X, Hua L, Wang J, Nelson S, Ouyang J. Ethanol inhibits lung clearance of Pseudomonas aeruginosa by a neutrophil and nitric oxide-dependent mechanism in vivo. Alcohol Clin Exp Res 23: 735-744, 1999.
11. Guidot D, Brown L. Mitochondrial glutathione replacement restores surfactant synthesis and secretion in alveolar epithelial cells of ethanol-fed rats. Alcohol Clin Exp Res 24: 1070-1076, 2000.
12. Holguin F, Moss I, Brown LA, Guidot DM. Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats. J Clin Invest 101: 761-768, 1998.
13. Holguin F, Moss MI, Brown LAS, Guidot DM. Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats. J Clin Invest 101: 761-768, 1998.
14. Jones DP, Moody VC Jr, Carlson JL, Lynn MJ, Sternberg P Jr. Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses. Free Radic Biol Med 33: 1290-1300, 2002.
15. + exchanger. Biochim Biophys Acta 1024: 385-389, 1990.
16. Lazebnik YA, Takahashi A, Moir RD, Goldman RD, Poirier GG, Kaufmann SH, Earnshaw WC. Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc Natl Acad Sci USA 92: 9042-9046, 1995.
17. Lieber CS. Biochemical factors in alcoholic liver disease. Semin Liver Dis 13: 136-153, 1993.
18. Lieber CS. Medical disorders of alcoholism. N Engl J Med 333: 1058-1065, 1995.
19. Loeb G, Skelton D, Coates T, Forman H. Role of selenium-dependent glutathione peroxidase in antioxidant defenses in rat alveolar macrophages. Exp Lung Res 14, Suppl: 921-936, 1988.
20. Meyer K, Powers C, Rosenthal N, Auerbach R. Alveolar macrophage surface carbohydrate expression is altered in interstitial lung disease as determined by lectin-binding profiles.. Am Rev Respir Dis 148: 1325-1334, 1993.
21. Moffat F Jr, Han T, Li Z, Peck M, Jy W, Ahn Y, Chu A, Bourguignon L. Supplemental L-arginine HCl augments bacterial phagocytosis in human polymorphonuclear leukocytes. J Cell Physiol 168: 26-33, 1996.
22. Moriarty SE, Shah JH, Lynn M, Jiang S, Openo K, Jones DP, Sternberg P. Oxidation of glutathione and cysteine in human plasma associated with smoking. Free Radic Biol Med 35: 1582-1588, 2003.
23. Moss M, Bucher B, Moore FA, Moore EE, Parsons PE. The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults. JAMA 275: 50-54, 1996.
24. Moss M, Guidot DM, Wong-Lambertina M, Ten Hoor T, Perez RL, Brown LA. The effects of chronic alcohol abuse on pulmonary glutathione homeostasis. Am J Respir Crit Care Med 161: 414-419, 2000.
25. Moss M, Guidot DM, Wong-Lambertina M, Ten Hoor T, Perez RL, Brown LAS. The effects of chronic alcohol abuse on pulmonary glutathione homeostasis. Am J Respir Crit Care Med 161: 414-419, 2000.
26. Moss M, Steinberg K, Guidot D, Duhon G, Treece P, Wolken R, Hudson L, Parsons P. The effect of chronic alcohol abuse on the incidence of ARDS and the severity of the multiple organ dysfunction syndrome in adults with septic shock: an interim and multivariate analysis. Chest 116: 97S-98S, 1999.
27. Omidvari K, Casey R, Nelson S, Olariu R, Shellito J. Alveolar macrophage release of tumor necrosis factor-α in chronic alcoholics without liver disease. Alcohol Clin Exp Res 22: 567-572, 1998.
28. Patel-King RS, Benashki SE, Harrison A, King SM. Two functional thioredoxins containing redox-sensitive vicinal dithiols from the Chlamydomonas outer dynein arm. J Biol Chem 271: 6283-6291, 1996.
29. Pietarinen P, Raivio K, Devlin R, Crapo J, Chang L, Kinnula V. Catalase and glutathione reductase protection of human alveolar macrophages during oxidant exposure in vitro. Am J Respir Cell Mol Biol 13: 434-441, 1995.
30. Pitzurra L, Blasi E, Bartoli A, Marconi P, Bistoni F. A rapid objective immunofluorescence microassay. Application for detection of surface and intracellular antigens. J Immunol Methods 135: 71-75, 1990.
31. Rajkovic I, Williams R. Inhibition of neutrophil function by hydrogen peroxide. Effect of SH-group-containing compounds. Biochem Pharmacol 34: 2083-2090, 1985.
32. Seres T, Knickelbein R, Warshaw J, Johnston R Jr. The phagocytosis-associated respiratory burst in human monocytes is associated with increased uptake of glutathione. J Immunol 165: 3333-3340, 2000.
33. Standiford TJ, Danforth JM. Ethanol feeding inhibits proinflammatory cytokine expression from murine alveolar macrophages ex vivo. Alcohol Clin Exp Res 21: 1212-1217, 1997.
34. Zhang Z, Bagby GJ, Stoltz D, Oliver P, Schwarzenberger PO, Kolls JK. Prolonged ethanol treatment enhances lipopolysaccharide/phorbol myristate acetate-induced tumor necrosis factor-α production in human monocytic cells. Alcohol Clin Exp Res 25: 444-449, 2001.
35. Zisman DA, Strieter RM, Kunkel SL, Tsai WC, Wilkowski JM, Bucknell KA, Standiford TJ. Ethanol feeding impairs innate immunity and alters the expression of Th1- and Th2-phenotype cytokines in murine Klebsiella pneumonia. Alcohol Clin Exp Res 22: 621-627, 1998.