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Volumn 15, Issue 5, 2014, Pages 8443-8457

Inhibitory effects of palmultang on inflammatory mediator production related to suppression of NF-κB and MAPK pathways and induction of HO-1 expression in macrophages

Author keywords

Heme oxygenase 1; Inducible nitric oxide synthase; Mitogen activated protein kinase; Nuclear factor kappaB; Palmultang

Indexed keywords

ALBIFLORIN; DEXAMETHASONE; FERULIC ACID; GLYCYRRHIZIC ACID; HEME OXYGENASE 1; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PAEONIFLORIN; PALMULTANG; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; AUTACOID; LIPOPOLYSACCHARIDE; PLANT EXTRACT;

EID: 84900515353     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15058443     Document Type: Article
Times cited : (17)

References (34)
  • 1
    • 84900502382 scopus 로고    scopus 로고
    • Effect of Paljin-tang on Surgically Induced Endometriosis in Rats
    • Lee, M.J.; Lim, E.M.; Kwon, K.R. Effect of Paljin-tang on Surgically Induced Endometriosis in Rats. J. Orient. Obstet. Gynecol. 2006, 19, 83-94.
    • (2006) J. Orient. Obstet. Gynecol. , vol.19 , pp. 83-94
    • Lee, M.J.1    Lim, E.M.2    Kwon, K.R.3
  • 2
    • 84900482846 scopus 로고    scopus 로고
    • The Effect of Palmultang on the Ovarian Functions and Differential Gene Expression of Caspase-3, MAPK and MPG in Female Mice
    • Joo, J.M.; Kim, D.C.; Back, S.H.; Kim, E.H. The Effect of Palmultang on the Ovarian Functions and Differential Gene Expression of Caspase-3, MAPK and MPG in Female Mice. J. Orient. Obstet. Gynecol. 2007, 20, 91-110.
    • (2007) J. Orient. Obstet. Gynecol. , vol.20 , pp. 91-110
    • Joo, J.M.1    Kim, D.C.2    Back, S.H.3    Kim, E.H.4
  • 3
    • 0025390287 scopus 로고
    • Macrophages: Important physiologic and pathologic sources of polypeptide growth factors
    • Pierce, G.F. Macrophages: Important physiologic and pathologic sources of polypeptide growth factors. Am. J. Respir. Cell Mol. Biol. 1990, 2, 233-234.
    • (1990) Am. J. Respir. Cell Mol. Biol. , vol.2 , pp. 233-234
    • Pierce, G.F.1
  • 4
    • 0034008927 scopus 로고    scopus 로고
    • Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages
    • Wadleigh, D.J.; Reddy, S.T.; Kopp, E.; Ghosh, S.; Herschman, H.R. Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages. J. Biol. Chem. 2000, 275, 6259-6266.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6259-6266
    • Wadleigh, D.J.1    Reddy, S.T.2    Kopp, E.3    Ghosh, S.4    Herschman, H.R.5
  • 5
    • 24644508560 scopus 로고    scopus 로고
    • Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: Further mechanistic studies
    • Becker, S.; Mundandhara, S.; Devlin, R.B.; Madden, M. Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: Further mechanistic studies. Toxicol. Appl. Pharmacol. 2005, 207, 269-275.
    • (2005) Toxicol. Appl. Pharmacol. , vol.207 , pp. 269-275
    • Becker, S.1    Mundandhara, S.2    Devlin, R.B.3    Madden, M.4
  • 6
    • 36849072564 scopus 로고    scopus 로고
    • Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-kappaB inactivation in RAW 264.7 macrophage cells
    • Kim, J.B.; Han, A.R.; Park, E.Y.; Kim, J.Y.; Cho, W.; Lee, J.; Seo, E.K.; Lee, K.T. Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-kappaB inactivation in RAW 264.7 macrophage cells. Biol. Pharm. Bull. 2007, 30, 2345-2351.
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 2345-2351
    • Kim, J.B.1    Han, A.R.2    Park, E.Y.3    Kim, J.Y.4    Cho, W.5    Lee, J.6    Seo, E.K.7    Lee, K.T.8
  • 7
    • 77952828647 scopus 로고    scopus 로고
    • Heme oxygenase-1: Its therapeutic roles in inflammatory diseases
    • Pae, H.O.; Chung, H.T. Heme oxygenase-1: Its therapeutic roles in inflammatory diseases. Immune Netw. 2009, 9, 12-19.
    • (2009) Immune Netw. , vol.9 , pp. 12-19
    • Pae, H.O.1    Chung, H.T.2
  • 8
    • 38949110010 scopus 로고    scopus 로고
    • Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages
    • Ashino, T.; Yamanaka, R.; Yamamoto, M.; Shimokawa, H.; Sekikawa, K.; Iwakura, Y.; Shioda, S.; Numazawa, S.; Yoshida, T. Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages. Mol. Immunol. 2008, 45, 2106-2115.
    • (2008) Mol. Immunol. , vol.45 , pp. 2106-2115
    • Ashino, T.1    Yamanaka, R.2    Yamamoto, M.3    Shimokawa, H.4    Sekikawa, K.5    Iwakura, Y.6    Shioda, S.7    Numazawa, S.8    Yoshida, T.9
  • 9
    • 0027245086 scopus 로고
    • Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B
    • De Martin, R.; Vanhove, B.; Cheng, Q.; Hofer, E.; Csizmadia, V.; Winkler, H.; Bach, F.H. Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B. EMBO J. 1993, 12, 2773-2779.
    • (1993) EMBO J. , vol.12 , pp. 2773-2779
    • De Martin, R.1    Vanhove, B.2    Cheng, Q.3    Hofer, E.4    Csizmadia, V.5    Winkler, H.6    Bach, F.H.7
  • 10
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl, H.L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999, 18, 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 11
    • 0030271387 scopus 로고    scopus 로고
    • NF-kappa B: Ten years after
    • Baeuerle, P.A.; Baltimore, D. NF-kappa B: Ten years after. Cell 1996, 87, 13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 12
    • 0030898417 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways
    • Robinson, M.J.; Cobb, M.H. Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol. 1997, 9, 180-186.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 180-186
    • Robinson, M.J.1    Cobb, M.H.2
  • 13
    • 0347993913 scopus 로고    scopus 로고
    • Nitric oxide and superoxide in inflammation and immune regulation
    • Guzik, T.J.; Korbut, R.; Adamek-Guzik, T. Nitric oxide and superoxide in inflammation and immune regulation. J. Physiol. Pharmacol. 2003, 54, 469-487.
    • (2003) J. Physiol. Pharmacol. , vol.54 , pp. 469-487
    • Guzik, T.J.1    Korbut, R.2    Adamek-Guzik, T.3
  • 14
    • 0030040255 scopus 로고    scopus 로고
    • Selective pharmacological inhibition of distinct nitric oxide synthase isoforms
    • Southan, G.J.; Szabo, C. Selective pharmacological inhibition of distinct nitric oxide synthase isoforms. Biochem. Pharmacol. 1996, 51, 383-394.
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 383-394
    • Southan, G.J.1    Szabo, C.2
  • 15
    • 33847112418 scopus 로고    scopus 로고
    • The NF-kappaB regulatory network
    • Brasier, A.R. The NF-kappaB regulatory network. Cardiovasc. Toxicol. 2006, 6, 111-130.
    • (2006) Cardiovasc. Toxicol. , vol.6 , pp. 111-130
    • Brasier, A.R.1
  • 16
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-kappaB: Players, pathways, perspectives
    • Gilmore, T.D. Introduction to NF-kappaB: Players, pathways, perspectives. Oncogene 2006, 25, 6680-6684.
    • (2006) Oncogene , vol.25 , pp. 6680-6684
    • Gilmore, T.D.1
  • 17
    • 0042809629 scopus 로고    scopus 로고
    • Identification of a nuclear factor kappa B-dependent gene network
    • Tian, B.; Brasier, A.R. Identification of a nuclear factor kappa B-dependent gene network. Recent Prog. Horm. Res. 2003, 58, 95-130.
    • (2003) Recent Prog. Horm. Res. , vol.58 , pp. 95-130
    • Tian, B.1    Brasier, A.R.2
  • 18
    • 0028881118 scopus 로고
    • Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages
    • Chen, F.; Kuhn, D.C.; Sun, S.C.; Gaydos, L.J.; Demers, L.M. Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages. Biochem. Biophys. Res. Commun. 1995, 214, 839-846.
    • (1995) Biochem. Biophys. Res. Commun. , vol.214 , pp. 839-846
    • Chen, F.1    Kuhn, D.C.2    Sun, S.C.3    Gaydos, L.J.4    Demers, L.M.5
  • 19
    • 0029658494 scopus 로고    scopus 로고
    • Manipulation of distinct NFkappaB proteins alters interleukin-1beta-induced human rheumatoid synovial fibroblast prostaglandin E2 formation
    • Roshak, A.K.; Jackson, J.R.; McGough, K.; Chabot-Fletcher, M.; Mochan, E.; Marshall, L.A. Manipulation of distinct NFkappaB proteins alters interleukin-1beta-induced human rheumatoid synovial fibroblast prostaglandin E2 formation. J. Biol. Chem. 1996, 271, 31496-31501.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31496-31501
    • Roshak, A.K.1    Jackson, J.R.2    McGough, K.3    Chabot-Fletcher, M.4    Mochan, E.5    Marshall, L.A.6
  • 20
    • 0027162479 scopus 로고
    • Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog
    • Xie, W.; Merrill, J.R.; Bradshaw, W.S.; Simmons, D.L. Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog. Arch. Biochem. Biophys. 1993, 300, 247-252.
    • (1993) Arch. Biochem. Biophys. , vol.300 , pp. 247-252
    • Xie, W.1    Merrill, J.R.2    Bradshaw, W.S.3    Simmons, D.L.4
  • 21
    • 14644424029 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kappaB activation in RAW 264.7 cells
    • Ahn, K.S.; Noh, E.J.; Zhao, H.L.; Jung, S.H.; Kang, S.S.; Kim, Y.S. Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kappaB activation in RAW 264.7 cells. Life Sci. 2005, 76, 2315-2328.
    • (2005) Life Sci. , vol.76 , pp. 2315-2328
    • Ahn, K.S.1    Noh, E.J.2    Zhao, H.L.3    Jung, S.H.4    Kang, S.S.5    Kim, Y.S.6
  • 22
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB. A pivotal transcription factor in chronic inflammatory diseases
    • Barnes, P.J.; Karin, M. Nuclear factor-kappaB. A pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 1997, 336, 1066-1071.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 23
    • 0031591592 scopus 로고    scopus 로고
    • Upstream NF-kappaB site is required for the maximal expression of mouse inducible nitric oxide synthase gene in interferon-gamma plus lipopolysaccharide induced RAW 264.7 macrophages
    • Kim, Y.M.; Lee, B.S.; Yi, K.Y.; Paik, S.G. Upstream NF-kappaB site is required for the maximal expression of mouse inducible nitric oxide synthase gene in interferon-gamma plus lipopolysaccharide induced RAW 264.7 macrophages. Biochem. Pharmacol. 1997, 236, 655-660.
    • (1997) Biochem. Pharmacol. , vol.236 , pp. 655-660
    • Kim, Y.M.1    Lee, B.S.2    Yi, K.Y.3    Paik, S.G.4
  • 24
    • 0032537557 scopus 로고    scopus 로고
    • Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW 264.7 macrophages
    • Caivano, M. Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW 264.7 macrophages. FEBS Lett. 1999, 429, 249-253.
    • (1999) FEBS Lett. , vol.429 , pp. 249-253
    • Caivano, M.1
  • 25
    • 84860388927 scopus 로고    scopus 로고
    • 5-Hydroxymethylfurfural from black garlic extract prevents TNFα-induced monocytic cell adhesion to HUVECs by suppression of vascular cell adhesion molecule-1 expression, reactive oxygen species generation and NF-κB activation
    • Kim, H.K.; Choi, Y.W.; Lee, E.N.; Park, J.K.; Kim, S.G.; Park, D.J.; Kim, B.S.; Lim, Y.T.; Yoon, S. 5-Hydroxymethylfurfural from black garlic extract prevents TNFα-induced monocytic cell adhesion to HUVECs by suppression of vascular cell adhesion molecule-1 expression, reactive oxygen species generation and NF-κB activation. Phytother. Res. 2011, 25, 965-974.
    • (2011) Phytother. Res. , vol.25 , pp. 965-974
    • Kim, H.K.1    Choi, Y.W.2    Lee, E.N.3    Park, J.K.4    Kim, S.G.5    Park, D.J.6    Kim, B.S.7    Lim, Y.T.8    Yoon, S.9
  • 26
    • 79959541467 scopus 로고    scopus 로고
    • Peoniflorin suppresses tumor necrosis factor-α induced chemokine production in human dermal microvascular endothelial cells by blocking nuclear factor-κB and ERK pathway
    • Chen, T.; Guo, Z.P.; Jiao, X.Y.; Jia, R.Z.; Zhang, Y.H.; Li, J.Y.; Huang, X.L.; Liu, H.J. Peoniflorin suppresses tumor necrosis factor-α induced chemokine production in human dermal microvascular endothelial cells by blocking nuclear factor-κB and ERK pathway. Arch. Dermatol. Res. 2011, 303, 351-360.
    • (2011) Arch. Dermatol. Res. , vol.303 , pp. 351-360
    • Chen, T.1    Guo, Z.P.2    Jiao, X.Y.3    Jia, R.Z.4    Zhang, Y.H.5    Li, J.Y.6    Huang, X.L.7    Liu, H.J.8
  • 27
    • 84865156883 scopus 로고    scopus 로고
    • Nodakenin suppresses lipopolysaccharide-induced inflammatory responses in macrophage cells by inhibiting tumor necrosis factor receptor-associated factor 6 and nuclear factor-κB pathways and protects mice from lethal endotoxin shock
    • Rim, H.K.; Cho, W.; Sung, S.H.; Lee, K.T. Nodakenin suppresses lipopolysaccharide-induced inflammatory responses in macrophage cells by inhibiting tumor necrosis factor receptor-associated factor 6 and nuclear factor-κB pathways and protects mice from lethal endotoxin shock. J. Pharmacol. Exp. Ther. 2012, 342, 654-664.
    • (2012) J. Pharmacol. Exp. Ther. , vol.342 , pp. 654-664
    • Rim, H.K.1    Cho, W.2    Sung, S.H.3    Lee, K.T.4
  • 29
    • 33745125984 scopus 로고    scopus 로고
    • Decursin inhibits induction of inflammatory mediators by blocking nuclear factor-kappaB activation in macrophages
    • Kim, J.H.; Jeong, J.H.; Jeon, S.T.; Kim, H.; Ock, J.; Suk, K.; Kim, S.I.; Song, K.S.; Lee, W.H. Decursin inhibits induction of inflammatory mediators by blocking nuclear factor-kappaB activation in macrophages. Mol. Pharmacol. 2006, 69, 1783-1790.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1783-1790
    • Kim, J.H.1    Jeong, J.H.2    Jeon, S.T.3    Kim, H.4    Ock, J.5    Suk, K.6    Kim, S.I.7    Song, K.S.8    Lee, W.H.9
  • 31
    • 50849123453 scopus 로고    scopus 로고
    • The inhibitory effect of quercitrin gallate on iNOS expression induced by lipopolysaccharide in Balb/c mice
    • Jo, H.Y.; Kim, Y.; Nam, S.Y.; Lee, B.J.; Kim, Y.B.; Yun, Y.W.; Ahn, B. The inhibitory effect of quercitrin gallate on iNOS expression induced by lipopolysaccharide in Balb/c mice. J. Vet. Sci. 2008, 9, 267-272.
    • (2008) J. Vet. Sci. , vol.9 , pp. 267-272
    • Jo, H.Y.1    Kim, Y.2    Nam, S.Y.3    Lee, B.J.4    Kim, Y.B.5    Yun, Y.W.6    Ahn, B.7
  • 33
    • 79551554973 scopus 로고    scopus 로고
    • Anti-inflammatory effect of ethyl acetate extract from Cissus quadrangularis Linn may be involved with induction of heme oxygenase-1 and suppression of NF-κB activation
    • Srisook, K.; Palachot, M.; Mongkol, N.; Srisook, E.; Sarapusit, S. Anti-inflammatory effect of ethyl acetate extract from Cissus quadrangularis Linn may be involved with induction of heme oxygenase-1 and suppression of NF-κB activation. J. Ethnopharmacol. 2011, 133, 1008-1014.
    • (2011) J. Ethnopharmacol. , vol.133 , pp. 1008-1014
    • Srisook, K.1    Palachot, M.2    Mongkol, N.3    Srisook, E.4    Sarapusit, S.5
  • 34
    • 84879293715 scopus 로고    scopus 로고
    • Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages
    • Kwon, D.J.; Ju, S.M.; Youn, G.S.; Choi, S.Y.; Park, J. Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages. Food Chem. Toxicol. 2013, 58, 479-486.
    • (2013) Food Chem. Toxicol. , vol.58 , pp. 479-486
    • Kwon, D.J.1    Ju, S.M.2    Youn, G.S.3    Choi, S.Y.4    Park, J.5


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