5-Hydroxymethylfurfural from black garlic extract prevents TNFα-induced monocytic cell adhesion to HUVECs by suppression of vascular cell adhesion molecule-1 expression, reactive oxygen species generation and NF-κB activation

Phytotherapy Research

Volumn 25, Issue 7, 2011, Pages 965-974

  Kim, Hye Kyung ^a   Choi, Young Whan ^b   Lee, Eun Na ^a   Park, Jin Kyeong ^a   Kim, Sun Gun ^b   Park, Da Jung ^b   Kim, Bong Seon ^a   Lim, Young Tak ^a,c   Yoon, Sik ^a,c  

^a Pusan National University School of Medicine   (South Korea)

^b Pusan National University   (South Korea)

^c Pusan National University Hospital   (South Korea)

Author keywords

5 Hydroxymethylfurfural; Aged black garlic; Cell adhesion molecules; Human umbilical vein endothelial cells; NF B transcription factor; Reactive oxygen species

Indexed keywords

5 HYDROXYMETHYLFURFURAL; GARLIC EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR ADHESION PROTEIN 1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL SURFACE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG ISOLATION; DRUG PURIFICATION; GARLIC; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INTERCELLULAR ADHESION MOLECULE 1 GENE; MONOCYTE; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; TRANSCRIPTION REGULATION; VASCULAR ADHESION PROTEIN 1 GENE;

ANTI-INFLAMMATORY AGENTS; CELL ADHESION; CELL ADHESION MOLECULES; CELL LINE; FURALDEHYDE; GARLIC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MONOCYTES; NF-KAPPA B; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

ALLIUM NIGRUM;

EID: 84860388927     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3351     Document Type: Article

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