The inhibitory effect of quercitrin gallate on iNOS expression induced by lipopolysaccharide in Balb/c mice

Journal of Veterinary Science

Volumn 9, Issue 3, 2008, Pages 267-272

  Jo, Hyun Ye ^a   Kim, Youngsoo ^a   Nam, Sang Yoon ^a   Beom, Jun Lee ^a   Kim, Yun Bae ^a   Young, Won Yun ^a   Ahn, Byeongwoo ^a  

^a Chungbuk National University   (South Korea)

Author keywords

Balb c mice; iNOS; Lipopolysaccharide; Quercitrin gallate

Indexed keywords

ANIMALIA; MAGNOLIOPHYTA; MUS; POLYGONACEAE; POLYGONUM LAPATHIFOLIUM;

EID: 50849123453     PISSN: 1229845X     EISSN: None     Source Type: Journal    
DOI: 10.4142/jvs.2008.9.3.267     Document Type: Article

References (29)

1. Akira S. Toll-like receptor and innate immunity. Adv Immunol 2001, 78, 1-56.
2. Aktan F. iNOS-mediated nitric oxide production and its regulation. Life Sci 2004, 75, 639-653.
3. Aktan F, Henness S, Roufogalis BD, Ammit AJ. Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-B-mediated iNOS protein expression. Nitric Oxide 2003, 8, 235-242.
4. Alderton WK, Cooper CE, Knowles RG. Nitric oxide synthases: structure, function and inhibition. Biochem J 2001, 357, 593-615.
5. Bogdan C. Nitric oxide and the immune response. Nature Immunol 2001, 2, 907-916.
6. Buttery LD, Evans TJ, Springall DR, Carpenter A, Cohen J, Polak JM. Immunochemical localization of inducible nitric oxide synthase in endotoxin-treated rats. Lab Invest 1994, 71, 755-764.
7. Grisham MB, Jourd'Heuil D, Wink DA. Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation. Am J Physiol 1999, 276, G315-321.
8. Guha M, Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 2001, 13, 85-94.
9. Haridas V, Arntzen CJ, Gutterman JU. Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappaB by inhibiting both its nuclear localization and ability to bind DNA. Proc Natl Acad Sci USA 2001, 98, 11557-11562.
10. Hubbard AK, Giardina C. Regulation of ICAM-1 expression in mouse macrophages. Inflammation 2000, 24, 115-125.
11. Hwang BY, Lee JH, Koo TH, Kim HS, Hong YS, Ro JS, Lee KS, Lee JJ. Kaurane diterpenes from Isodon japonicus inhibit nitric oxide and prostaglandin E2 production and NF-kappaB activation in LPS-stimulated macrophage RAW264.7 cells. Planta Med 2001, 67, 406-410.
12. Israël l A. The IKK complex: an integrator of all signals that activate NF-B? Trends Cell Biol 2000, 10, 129-133.
13. Jin HZ, Hwang BY, Kim HS, Lee JH, Kim YH, Lee JJ. Antiinflammatory constituents of Celastrus orbiculatus inhibit the NF-kappaB activation and NO production. J Nat Prod 2002, 65, 89-91.
14. Kim BH, Cho SM, Reddy AM, Kim YS, Min KR, Kim Y. Down-regulatory effect of quercitrin gallate on nuclear factor-κB-dependent inducible nitric oxide synthase expression in lipopolysaccharide-stimulated macrophages RAW 264.7. Biochem Pharmacol 2005, 69, 1577-1583.
15. Kim Y, Jang DS, Park SH, Yun J, Min BK, Min KR, Lee HK. Flavonol glycoside gallate and ferulate esters from persicaria lapathifolia as inhibitors of superoxide production in human monocytes stimulated by unopsonized zymosan. Planta Med 2000, 66, 72-74.
16. Lee JH, Koo TH, Yoon H, Jung HS, Jin HZ, Lee K, Hong YS, Lee JJ. Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid. Biochem Pharmacol 2006, 72, 1311-1321.
17. Lin YL, Lin JK. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol Pharmacol 1997, 52, 465-472.
18. Ma ZH, Ma QY, Sha HC, Wang LC. Effect of resveratrol on lipopolysaccharide-induced activation of rat peritoneal macrophages. Nan Fang Yi Ke Da Xue Xue Bao 2006, 26, 1363-1365.
19. Magnani M, Crinelli R, Bianchi M, Antonelli A. The ubiquitin-dependent proteolytic system and other potential targets for the modulation of nuclear factor-κB (NF-κB). Curr Drug Targets 2000, 1, 387-399.
20. Manna SK, Sah NK, Newman RA, Cisneros A, Aggarwal BB. Oleandrin suppresses activation of nuclear transcription factor-kappaB, activator protein-1, and c-Jun NH2-terminal kinase. Cancer Res 2000, 60, 3838-3847.
21. Mu MM, Chakravortty D, Sugiyama T, Koide N, Takahashi K, Mori I, Yoshida T, Yokochi T. The inhibitory action of quercetin on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells. J Endotoxin Res 2001, 7, 431-438.
22. Park HJ, Kim RG, Seo BR, Ha J, Ahn BT, Bok SH, Lee YS, Kim HJ, Lee KT. Saucernetin-7 and saucernetin-8 isolated from Saururus chinensis inhibit the LPS-induced production of nitric oxide and prostaglandin E2 in macrophage RAW264.7 cells. Planta Med 2003, 69, 947-950.
23. Peet GW, Li J. IκB kinases α and β show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin. J Biol Chem 1999, 274, 32655-32661.
24. Schmidt HH, Walter U. NO at work. Cell 1994, 78, 919-925.
25. Suzuki H, Chiba T, Kobayashi M, Takeuchi M, Furuichi K, Tanaka K. In vivo and in vitro recruitment of an IκBaα-ubiquitin ligase to IKappaBalpha phosphorylated by IKK, leading to ubiquitination. Biochem Biophys Res Commun 1999, 256, 121-126.
26. Tian B, Brasier AR. Identification of a nuclear factor kappa B-dependent gene network. Recent Prog Horm Res 2003, 58, 95-130.
27. Wadsworth TL, Koop DR. Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages. Biochem Pharmacol 1999, 57, 941-949.
28. Xie QW, Cho HJ, Calaycay J, Mumford RA, Swiderek KM, Lee TD, Ding A, Troso T, Nathan C. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 1992, 256, 225-228.
29. Xie QW, Kashiwabara Y, Nathan C. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J Biol Chem 1994, 269, 4705-4708.