Design and syntheses of anti-tuberculosis agents inspired by BTZ043 using a scaffold simplification strategy

ACS Medicinal Chemistry Letters

Volumn 5, Issue 5, 2014, Pages 587-591

  Tiwari, Rohit ^a   Möllmann, Ute ^b   Cho, Sanghyun ^c   Franzblau, Scott G ^c   Miller, Patricia A ^a   Miller, Marvin J ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b HANS KNÖLL INSTITUTE   (Germany)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

BTZ043; DprE1; Mycobacterium tuberculosis; nitroaromatics; scaffold simplification strategy

Indexed keywords

BENZOTHIAZINE DERIVATIVE; BTZ 043; ETHAMBUTOL; ISONIAZID; MOLECULAR SCAFFOLD; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; COVALENT BOND; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION;

EID: 84900449838     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml500039g     Document Type: Article

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