Synthesis and structure-activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 17, 2013, Pages 4919-4922

  Gao, Chao ^a   Ye, Ting Hong ^a   Wang, Ning Yu ^a   Zeng, Xiu Xiu ^b   Zhang, Li Dan ^a,b   Xiong, Ying ^a   You, Xin Yu ^a,b   Xia, Yong ^a   Xu, Ying ^a   Peng, Cui Ting ^a,b   Zuo, Wei Qiong ^a   Wei, Yuquan ^a   Yu, Luo Ting ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Benzothiazinone; DprE1; Structure activity relationships (SAR); Tuberculosis

Indexed keywords

BENZOTHIAZINONE DERIVATIVE; PIPERAZINE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; VERO CELL;

MYCOBACTERIUM TUBERCULOSIS;

BENZOTHIAZINONE; DPRE1; STRUCTURE-ACTIVITY RELATIONSHIPS (SAR); TUBERCULOSIS;

ANIMALS; ANTITUBERCULAR AGENTS; CERCOPITHECUS AETHIOPS; HUMANS; MYCOBACTERIUM TUBERCULOSIS; RATS; RATS, SPRAGUE-DAWLEY; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZINES; TUBERCULOSIS; VERO CELLS;

EID: 84881371356     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.06.069     Document Type: Article

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