Targeting intracellular degradation pathways for treatment of liver disease caused by α1-antitrypsin deficiency

Pediatric Research

Volumn 75, Issue 1-2, 2014, Pages 133-139

  Wang, Yan ^a,b   Perlmutter, David H ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; CASPASE; CLONIDINE; DIMEBON; FLUPHENAZINE; FLUSPIRILENE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MINOXIDIL; PHENOTHIAZINE DERIVATIVE; PIMOZIDE; RILMENIDINE; TRANSFORMING GROWTH FACTOR BETA; VERAPAMIL; ALPHA 1 ANTITRYPSIN; DRUG;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ANCA ASSOCIATED VASCULITIS; AUTOPHAGY; B LYMPHOCYTE; CAENORHABDITIS ELEGANS; ENDOPLASMIC RETICULUM STRESS; HUMAN; LIVER DISEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; WEGENER GRANULOMATOSIS; CLINICAL FEATURE; DEGRADATION; ENDOPLASMIC RETICULUM; LIVER CELL; LIVER FIBROSIS; PROTEIN DEGRADATION;

ALPHA 1-ANTITRYPSIN; ALPHA 1-ANTITRYPSIN DEFICIENCY; ANIMALS; AUTOPHAGY; CARBAMAZEPINE; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LIVER; MOLECULAR TARGETED THERAPY; PHENOTYPE; POINT MUTATION; PROTEOLYSIS;

EID: 84900418218     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2013.190     Document Type: Review

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