Effects of arginine concentration on the in Vitro expression of casein and mTOR pathway related genes in mammary epithelial cells from dairy cattle

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Wang, Mengzhi ^a,b,c   Xu, Bolin ^a   Wang, Hongrong ^a   Bu, Dengpan ^b   Wang, Jiaqi ^a,b   Loor, Juan Jose ^c  

^a YANGZHOU UNIVERSITY   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ARGININE; CASEIN; JANUS KINASE 2; MAMMALIAN TARGET OF RAPAMYCIN; STAT5 PROTEIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ARTICLE; BREAST EPITHELIUM; CONTROLLED STUDY; DAIRY CATTLE; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; ANIMAL; BOVINE; CELL CULTURE; DRUG EFFECTS; EPITHELIUM CELL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SIGNAL TRANSDUCTION; UDDER;

ANIMALS; ARGININE; CASEINS; CATTLE; CELLS, CULTURED; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MAMMARY GLANDS, ANIMAL; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84900418167     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095985     Document Type: Article

References (36)

1. Wu GY (2009) Amino acids: metabolism, functions, and nutrition. Amino Acids 37, 1-17.
2. Wu G, Bazer FW, Davis TA, Jaeger LA, Johnson GA, et al. (2007) Important roles for the arginine family of amino acids in swine nutrition and production. Livest Sci 112, 8-22. (Pubitemid 47516671)
3. Mateo RD, Wu G, Moon HK, Carroll JA, Kim SW (2008) Effects of dietary arginine supplementation during gestation and lactation on the performance of lactating primiparous sows and nursing piglets. J Animal Sci 86, 827-835. (Pubitemid 351535456)
4. Rhoads JM, Wu G (2009) Glutamine, arginine, and leucine signaling in the intestine. Amino Acids 7, 111-122.
5. Bequette BJ, Backwell FRC, Crompton LA (1998) Current concepts of amino acid and protein metabolism in the mammary gland of the lactating ruminant. J Dairy Sci 81, 2540-2559. (Pubitemid 128461063)
6. Lapierre H, Lobley GE, Doepel L, Raggio G, Rulquin H, et al. (2012) Triennial Lactation Symposium: Mammary metabolism of amino acids in dairy cows. J Animal Sci 90, 1708-1721.
7. Bionaz M, Hurley W, Loor J (2012) Milk protein synthesis in the lactating mammary gland: Insights from transcriptomics analyses. In: Hurley WH, editor. Milk Protein, Chapter 11. InTech North America, New York, USA. 285-324. Available: http://dx.doi.org/10.5772/46054. Accessed 2012 Sep 12.
8. Hanigan MD, Crompton LA, Bequette BJ, Mills JA, France J (2002) Modelling mammary metabolism in the dairy cow to predict milk constituent yield, with emphasis on amino acid metabolism and milk protein production: model evaluation. J Theor Biol 217, 311-330. (Pubitemid 35216434)
9. Rius AG, Appuhamy JA, Cyriac J, Kirovski D, Becvar O, et al. (2010) Regulation of protein synthesis in mammary glands of lactating dairy cows by starch and amino acids. J Dairy Sci 93, 3114-3127.
10. Appuhamy JADRN, Bell AL, Nayananjalie WAD, Escobar J, Hanigan MD (2011) Essential amino acids regulate both initiation and elongation of mRNA translation independent of insulin in MAC-T cells and bovine mammary tissue slices. J Nutr 141, 1209-1215.
11. Doepel L, Lapierre H (2011) Deletion of arginine from an abomasal infusion of amino acids does not decrease milk protein yield in Holstein cows. J Dairy Sci 94, 864-873.
12. Loor JJ, Cohick WS (2009) ASAS centennial paper: Lactation biology for the twenty - first century. J Animal Sci 87, 813-824.
13. Bionaz M, Loor JJ (2011) Gene networks driving bovine mammary protein synthesis during the lactation cycle. Bioinf Biol Insights 5, 83-98.
14. Chen LM, Li ZT, Wang MZ, Wang HR (2013) Preliminary report of arginine on synthesis and gene expression of casein in bovine mammary epithelial cell. IRJAS 3, 17-23.
15. O'Quinn PR, Knabe DA, Wu G (2002) Arginine catabolism in lactating porcine mammary tissue. J Animal Sci 80, 467-474. (Pubitemid 41138551)
16. Wu G (1996) An important role for pentose cycle in the synthesis of citrulline and proline from glutamine in porcine enterocytes. Arch Biochem Biophys 336, 224-230.
17. Xu BL, Wang MZ, Zhang XF, Ha S, Wang CY, et al. (2012) Arginine levels affect growth and CSN3 gene expression of dairy cows mammary epithelial cells in vitro. Chin J Animal Nutri 24, 852-858. (in Chinese with English abstract).
18. Bionaz M, Loor JJ (2007) Identification of reference genes for quantitative real-time PCR in the bovine mammary gland during the lactation cycle. Physiol Genomics 29, 312-319. (Pubitemid 47173302)
19. Gamboa A, Shibao C, Diedrich A, Paranjape SY, Farley G, et al. (2008) Excessive nitric oxide function and blood pressure regulation in patients with autonomic failure. Hypertension 51, 1531-1536.
20. Rhoads JM, Chen W, Gookin J, Wu GY, Fu Q, et al. (2004) Arginine stimulates intestinal cell migration through a focal adhesion kinase dependent mechanism. Gut 53, 514-522. (Pubitemid 38372975)
21. Jobgen WS, Fried SK, Fu WJ, Meininger CJ, Wu G (2006) Regulatory role for the arginine-nitric oxide pathway in energy-substrate metabolism. J Nutri Biochem 17, 571-588. (Pubitemid 44205442)
22. Mateo RD, Wu G, Bazer FW, Park JC, Shinzato I, et al. (2007) Dietary l-arginine supplementation enhances the reproductive performance of gilts. J Nutri 137, 652-656. (Pubitemid 46397498)
23. Guo Y, Xiao P, Lei S, Deng F, Xiao GG, et al. (2008) How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes. Acta Biochim Biophys Sin 40, 426-436. (Pubitemid 351704046)
24. Rosen JM, Wyszomierski SL, Hadsell D (1999) Regulation of milk protein gene expression. Annu Rev Nutri 19, 407-436. (Pubitemid 29380611)
25. Rijnkels M (2002) Multispecies comparison of the casein gene loci and evolution of casein gene family. J Mammary Gland Biol Neoplasia 7, 327-345.
26. Levy DE, Darnell Jr JE (2002) STATs: transcriptional control and biological impact. Nature Review 3, 651-662. (Pubitemid 34987786)
27. Watson CJ, Burdon TG (1996) Prolaction signal transduction mechanisms in the mammary gland: the role of the Jak/Stat pathway. Rev Reprod 1, 1-5.
28. Burgos SA, Dai M, Cant JP (2010) Nutrient availability and lactogenic hormones regulate mammary protein synthesis through the mammalian target of rapamycin signaling pathway. J Dairy Sci 93,153-161.
29. Yang J, Kennelly JJ, Baracos VE (2000) Physiological levels of Stat5 DNA binding activity and protein in bovine mammary gland. J Animal Sci 78, 3126-3134.
30. Toerien CA, Trout DR, Cant JP (2010) Nutritional stimulation of milk protein yield of cows is associated with changes in phosphorylation of mammary eukaryotic initiation factor 2 and ribosomal s6 kinase 1. J Nutri 140, 285-292.
31. Corl BA, Odle J, Niu X, Moeser AJ, Gatlin LA, et al. (2008) Arginine activates intestinal p70S6K and protein synthesis in piglet rotavirus enteritis. J Nutri 138, 24-29.
32. Yao K, Yin YL, Chu W, Liu Z, Deng D, et al. (2008) Dietary arginine supplementation increases mTOR signaling activity in skeletal muscle of neonatal pigs. J Nutri 138, 867-872. (Pubitemid 351571584)
33. Gingras AC, Gygi SP, Raught B, Polakiewicz RD, Abraham RT, et al. (1999) Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism. Genes Dev 13, 1422-1437. (Pubitemid 29270247)
34. Yanagiya A, Suyama E, Adachi H, Svitkin YV, Aza-Blanc P, et al. (2012) Translational homeostasis via the mRNA cap-binding protein, eIF4E. Mol Cell 46, 847-858.
35. Bauchart-Thevret C, Cui L, Wu GY, Burrin DG (2010) Arginine-induced stimulation of protein synthesis and survival in IPEC-J2 cells is mediated by mTOR but not nitric oxide. Am J Physiol Endocrinol Metab 299, E899-E909.
36. Raggio G, Pacheco D, Berthiaume R, Lobley GE, Pellerin D, et al. (2004) Effect of level of metabolizable protein on splanchnic flux of amino acids in lactating dairy cows. J Dairy Sci 87, 3461-3472. (Pubitemid 39408480)