Prolactin signal transduction mechanisms in the mammary gland: The role of the Jak/Stat pathway

Reviews of Reproduction

Volumn 1, Issue 1, 1996, Pages 1-5

  Watson, Christine J ^a   Burdon, Thomas G ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; JAK2 PROTEIN, HUMAN; JANUS KINASE 2; MILK PROTEIN; ONCOPROTEIN; PROLACTIN; PROTEIN TYROSINE KINASE; STAT5 PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL; BREAST; FEMALE; HUMAN; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; UDDER;

ANIMALS; BREAST; DNA-BINDING PROTEINS; FEMALE; HUMANS; JANUS KINASE 2; MAMMARY GLANDS, ANIMAL; MILK PROTEINS; PROLACTIN; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

ANIMALIA; JANUS;

EID: 0030020748     PISSN: 13596004     EISSN: None     Source Type: Journal    
DOI: 10.1530/ror.0.0010001     Document Type: Article

References (23)

1. Azam M, Erdjument-Bromage H, Kreider BL, Xia M, Quelle F, Basu R, Saris C, Tempst P, Ihle JN and Schindler C (1995) Interleukin-3 signals through multiple isoforms of Stat5 EMBO Journal 14 1402-1411
2. Burdon TG, Maitland KA, Clark AJ, Wallace R and Watson CJ (1994) Regulation of the sheep β-lactoglobulin gene by lactogenic hormones is mediated by a transcription factor that binds an interferon-γ activation site (GAS)-related element Molecular Endocrinology 8 1528-1536
3. Campbell GS, Argetsinger LS, Ihle JN, Kelly PA, Rillema JA and Carter-Su C (1994) Activation of Jak2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary-gland explants Proceedings of the National Academy of Sciences USA 91 5232-5236
4. Clevenger CV and Medaglia MV (1994) The protein tyrosine kinase p59fyn is associated with prolactin receptor and is activated by prolactin stimulation of T-lymphocytes Molecular Endocrinology 8 674-681
5. Clevenger CV, Altmann SW and Prystowsky MB (1991) Requirement of nuclear prolactin for interleukin-2-stimulated proliferation of T lymphocytes Science 253 77-79
6. Demmer J, Burdon TG, Djiane J, Watson CJ and Clark AJ (1995) The proximal MPBF (MGF) binding site mediates the prolactin responsiveness of the sheep BLG promoter in CHO cells Molecular and Cellular Endocrinology 107 113-121
7. Gouilleux F, Wakao H, Mundt M and Groner B (1994) Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription EMBO Journal 13 4361-1369
8. Gouilleux F, Pallard C, Dusanter-Fourt I, Wakao H, Haldosen L-A, Norstedt G, Levy D and Groner B (1995) Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony-stimulating factor induce MGF-Stat5 DNA binding activity EMBO Journal 14 2005-2013
9. Houdebine LM, Djiane J, Dusanter-Fourt I, Martel P, Kelly PA, Devinoy E and Servely JL (1985) Hormone action controlling mammary activity Journal of Dairy Science 68 489-500
10. Kelly PA, Djiane J and Edery M (1992) Different forms of the prolactin receptor: insights into the mechanism of prolactin action Trends in Endocrinology and Metabolism 3 54-59
11. Lebrun J-J, Ali S, Ullrich A and Kelly PA (1995) Proline-rich sequence-mediated Jak2 association to the prolactin receptor is required but not sufficient for signal transduction Journal of Biological Chemistry 270 10664-10670
12. Li S and Rosen JM (1995) Nuclear factor 1 and mammary gland factor (STAT5) play a critical role in regulating rat whey acidic protein gene expression in transgenic mice Molecular and Cellular Biology 15 2063-2070
13. Mui AL-F, Wakao H, O'Farrell A-M, Harada N and Miyajima A (1995) Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs EMBO Journal 14 1166-1175
14. Nicoll CS (1974) Physiological actions of prolactin. In Handbook of Physiology pp 253-292 Ed. E Knobil and W Sawyer. Williams and Wilkins, Baltimore
15. Schindler C and Darnell JE, Jr (1995) Transcriptional responses to polypeptide ligands Annual Reviews of Biochemistry 64 621-651
16. Schmitt-Ney M, Doppler W, Ball RK and Groner B (1991) β-Casein gene promoter activity is regulated by the hormone-mediated relief of transcriptional repression and a mammary gland-specific nuclear factor Molecular and Cellular Biology 11 3745-3755
17. Stahl N, Farruggella TJ, Boulton TG, Zhong Z, Darnell JE, Jr and Yancopoulos GD (1995) Choice of STATs and other substrates specified by modular tyrosine based motifs in cytokine receptors Science 267 1349-1353
18. Streuli CH, Edwards GM, Whitelaw CBA, Burdon TG, Delcommenne M, Schindler C and Watson CJ Stat5 as a target for regulation by extracellular matrix Journal of Biological Chemistry 270 21639-21644
19. Taniguchi T (1995) Cytokine signalling through nonreceptor protein tyrosine kinases Science 268 251-255
20. Wakao H, Gouilleux F and Groner B (1994) Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response EMBO Journal 13 2182-2191
21. Watson CJ, Gordon KE, Robertson M and Clark AJ (1991) Interaction of DNA-binding proteins with a milk protein gene promoter in vitro: identification of a mammary gland specific factor Nucleic Acids Research 19 6603-6610
22. Wilks AF, Harpur AG, Kurban RR, Ralph SJ, Zurcher G and Ziemiecki A (1991) Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain define a new class of protein kinase Molecular and Cellular Biology 11 2057-2065
23. Zhang X, Blenis J, Li H-C, Schindler C and Chen-Kiang S (1995) Requirement of serine phosphorylation for formation of STAT-promoter complexes Science 267 1990-1994