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Volumn 9, Issue 1, 2014, Pages

Bacteria induce prolonged PMN survival via a phosphatidylcholine-specific phospholipase C- And protein kinase C-dependent mechanism

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; DEATH RECEPTOR; INTERLEUKIN 8; LIGAND; PHOSPHATIDYLCHOLINE SPECIFIC PHOSPHOLIPASE C; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84900411329     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087859     Document Type: Article
Times cited : (4)

References (51)
  • 1
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • Mantovani A, Cassatella MA, Costantini C, Jaillon S (2011) Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 11: 519-531.
    • (2011) Nat Rev Immunol , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 2
    • 0031004487 scopus 로고    scopus 로고
    • Apoptosis in resolution of inflammation
    • Savill J (1997) Apoptosis in resolution of inflammation. J Leukoc Biol 61: 375-380.
    • (1997) J Leukoc Biol , vol.61 , pp. 375-380
    • Savill, J.1
  • 3
    • 0344393518 scopus 로고    scopus 로고
    • Regulation of neutrophil apoptosis via death receptors
    • DOI 10.1007/s00018-003-3110-z
    • Akgul C, Edwards SW (2003) Regulation of neutrophil apoptosis via death receptors. Cell Mol Life Sci 60: 2402-2408. (Pubitemid 37487260)
    • (2003) Cellular and Molecular Life Sciences , vol.60 , Issue.11 , pp. 2402-2408
    • Akgul, C.1    Edwards, S.W.2
  • 4
    • 0344603595 scopus 로고    scopus 로고
    • Regulation of Fas antibody induced neutrophil apoptosis is both caspase and mitochondrial dependent
    • DOI 10.1016/S0014-5793(99)00688-2, PII S0014579399006882
    • Watson RW, O'Neill A, Brannigan AE, Coffey R, Marshall JC, et al. (1999) Regulation of Fas antibody induced neutrophil apoptosis is both caspase and mitochondrial dependent. FEBS Lett 453: 67-71. (Pubitemid 29335475)
    • (1999) FEBS Letters , vol.453 , Issue.1-2 , pp. 67-71
    • William, R.W.G.1    O'Neill, A.2    Brannigen, A.E.3    Coffey, R.4    Marshall, J.C.5    Brady, H.R.6    Fitzpatrick, J.M.7
  • 5
    • 0034641931 scopus 로고    scopus 로고
    • Corpse clearance defines the meaning of cell death
    • Savill J, Fadok V (2000) Corpse clearance defines the meaning of cell death. Nature 407: 784-788.
    • (2000) Nature , vol.407 , pp. 784-788
    • Savill, J.1    Fadok, V.2
  • 8
    • 80855140192 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae-mediated inhibition of apoptotic signalling in polymorphonuclear leukocytes
    • Chen A, Seifert HS (2011) Neisseria gonorrhoeae-mediated inhibition of apoptotic signalling in polymorphonuclear leukocytes. Infect Immun 79: 4447-4458.
    • (2011) Infect Immun , vol.79 , pp. 4447-4458
    • Chen, A.1    Seifert, H.S.2
  • 9
    • 0037097677 scopus 로고    scopus 로고
    • L via an oxygen-dependent pathway
    • Perskvist N, Long M, Stendahl O, Zheng L (2002) Mycobacterium tuberculosis promotes apoptosis in human neutrophils by activating caspase-3 and altering expression of Bax/Bcl-xL via an oxygen-dependent pathway. J Immunol 168: 6358-6365. (Pubitemid 34620059)
    • (2002) Journal of Immunology , vol.168 , Issue.12 , pp. 6358-6365
    • Perskvist, N.1    Long, M.2    Stendahl, O.3    Zheng, L.4
  • 11
    • 0021366411 scopus 로고
    • Molecular cloning of the temperature-inducible outer membrane protein 1 of Yersinia pseudotuberculosis
    • Bolin I, Wolf-Watz H (1984) Molecular cloning of the temperature- inducible outer membrane protein 1 of Yersinia pseudotuberculosis. Infect Immun 43: 72-78. (Pubitemid 14218005)
    • (1984) Infection and Immunity , vol.43 , Issue.1 , pp. 72-78
    • Bolin, I.1    Wolf, W.H.2
  • 12
    • 0020073144 scopus 로고
    • Temperature-inducible outer membrane protein of Yersinia pseudotuberculosis and Yersinia enterocolitica is associated with the virulence plasmid
    • Bolin I, Norlander L, Wolf-Watz H (1982) Temperature-inducible outer membrane protein of Yersinia pseudotuberculosis and Yersinia enterocolitica is associated with the virulence plasmid. Infect Immun 37: 506-512. (Pubitemid 12100033)
    • (1982) Infection and Immunity , vol.37 , Issue.2 , pp. 506-512
    • Bolin, I.1    Norlander, L.2    Wolf-Watz, H.3
  • 14
    • 0033764483 scopus 로고    scopus 로고
    • Assembly and function of type III secretory systems
    • Cornelis GR, Van Gijsegem F (2000) Assembly and function of type III secretory systems. Annu Rev Microbiol 54: 735-774.
    • (2000) Annu Rev Microbiol , vol.54 , pp. 735-774
    • Cornelis, G.R.1    Van Gijsegem, F.2
  • 15
    • 0017395981 scopus 로고
    • A new alkaloid AM 2282 of Streptomyces origin taxonomy, fermentation, isolation and preliminary characterization
    • Omura S, Iwai Y, Hirano A, Nakagawa A, Awaya J, et al. (1977) A new alkaloid AM-2282 OF Streptomyces origin. Taxonomy, fermentation, isolation and preliminary characterization. J Antibiot 30: 275-282. (Pubitemid 8119845)
    • (1977) Journal of Antibiotics , vol.30 , Issue.4 , pp. 275-282
    • Omura, S.1    Iwai, Y.2    Hirano, A.3
  • 16
    • 0024394417 scopus 로고
    • Staurosporine, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases
    • DOI 10.1016/0165-6147(89)90263-0
    • Ruegg UT, Burgess GM (1989) Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Trends Pharmacol Sci 10: 218-220. (Pubitemid 19146392)
    • (1989) Trends in Pharmacological Sciences , vol.10 , Issue.6 , pp. 218-220
    • Ruegg, U.T.1    Burgess, G.M.2
  • 17
    • 78651112199 scopus 로고    scopus 로고
    • Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine
    • Couto D, Ribeiro D, Freitas M, Gomes A, Lima JL, et al. (2010) Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine. Redox Rep 15: 259-267.
    • (2010) Redox Rep , vol.15 , pp. 259-267
    • Couto, D.1    Ribeiro, D.2    Freitas, M.3    Gomes, A.4    Lima, J.L.5
  • 18
    • 70449488334 scopus 로고    scopus 로고
    • Sulphasalazine accelerates apoptosis in neutrophils exposed to immune complex: Role of caspase pathway
    • Bertolotto M, Dallegri F, Dapino P, Quercioli A, Pende A, et al. (2009) Sulphasalazine accelerates apoptosis in neutrophils exposed to immune complex: Role of caspase pathway. Clin Exp Pharmacol Physiol 36: 1132-1135.
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , pp. 1132-1135
    • Bertolotto, M.1    Dallegri, F.2    Dapino, P.3    Quercioli, A.4    Pende, A.5
  • 19
    • 77249087063 scopus 로고    scopus 로고
    • Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin
    • Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, et al. (2010) Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat Chem Biol 6: 209-217.
    • (2010) Nat Chem Biol , vol.6 , pp. 209-217
    • Schneider-Poetsch, T.1    Ju, J.2    Eyler, D.E.3    Dang, Y.4    Bhat, S.5
  • 20
    • 0036322385 scopus 로고    scopus 로고
    • Yersinia type III secretion: Send in the effectors
    • Cornelis GR (2002) Yersinia type III secretion: send in the effectors. J Cell Biol 158: 401-408.
    • (2002) J Cell Biol , vol.158 , pp. 401-408
    • Cornelis, G.R.1
  • 21
    • 0141705297 scopus 로고    scopus 로고
    • Toll-like receptors stimulate human neutrophil function
    • DOI 10.1182/blood-2003-04-1078
    • Hayashi F, Means TK, Luster AD (2003) Toll-like receptors stimulate human neutrophil function. Blood 102: 2660-2669. (Pubitemid 37193610)
    • (2003) Blood , vol.102 , Issue.7 , pp. 2660-2669
    • Hayashi, F.1    Means, T.K.2    Luster, A.D.3
  • 23
    • 0027248964 scopus 로고
    • Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C
    • Wilkinson SE, Parker PJ, Nixon JS (1993) Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem J 294 (Pt 2): 335-337. (Pubitemid 23268828)
    • (1993) Biochemical Journal , vol.294 , Issue.2 , pp. 335-337
    • Wilkinson, S.E.1    Parker, P.J.2    Nixon, J.S.3
  • 24
    • 0028961653 scopus 로고
    • Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors
    • Budworth J, Gescher A (1995) Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors. FEBS Lett 362: 139-142.
    • (1995) FEBS Lett , vol.362 , pp. 139-142
    • Budworth, J.1    Gescher, A.2
  • 26
    • 0028868141 scopus 로고
    • The bisindolylmaleimide GF 109203X, a selective inhibitor of protein kinase C, does not inhibit the potentiating effect of phorbol ester on ethanol-induced phospholipase C-mediated hydrolysis of phosphatidylethanolamine
    • Kiss Z, Phillips H, Anderson WH (1995) The bisindolylmaleimide GF 109203X, a selective inhibitor of protein kinase C, does not inhibit the potentiating effect of phorbol ester on ethanol-induced phospholipase C-mediated hydrolysis of phosphatidylethanolamine. Biochim Biophys Acta 1265: 93-95.
    • (1995) Biochim Biophys Acta , vol.1265 , pp. 93-95
    • Kiss, Z.1    Phillips, H.2    Anderson, W.H.3
  • 27
    • 3042736838 scopus 로고    scopus 로고
    • 2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells
    • DOI 10.1161/01.CIR.0000133384.38551.A8
    • Kouroedov A, Eto M, Joch H, Volpe M, Luscher TF, et al. (2004) Selective inhibition of protein kinase Cbeta2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 110: 91-96. (Pubitemid 38880139)
    • (2004) Circulation , vol.110 , Issue.1 , pp. 91-96
    • Kouroedov, A.1    Eto, M.2    Joch, H.3    Volpe, M.4    Luscher, T.F.5    Cosentino, F.6
  • 28
    • 0030603158 scopus 로고    scopus 로고
    • Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes
    • DOI 10.1016/0014-5793(96)00785-5
    • Gschwendt M, Dieterich S, Rennecke J, Kittstein W, Mueller HJ, et al. (1996) Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett 392: 77-80. (Pubitemid 26276722)
    • (1996) FEBS Letters , vol.392 , Issue.2 , pp. 77-80
    • Gschwendt, M.1    Dieterich, S.2    Rennecke, J.3    Kittstein, W.4    Mueller, H.-J.5    Johannes, F.-J.6
  • 30
    • 0025303073 scopus 로고
    • Receptor-coupled signal transduction in human polymorphonuclear neutrophils: Effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness
    • Smith RJ, Sam LM, Justen JM, Bundy GL, Bala GA, et al. (1990) Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness. J Pharmacol Exp Ther 253: 688-697. (Pubitemid 20181715)
    • (1990) Journal of Pharmacology and Experimental Therapeutics , vol.253 , Issue.2 , pp. 688-697
    • Smith, R.J.1    Sam, L.M.2    Justen, J.M.3    Bundy, G.L.4    Bala, G.A.5    Bleasdale, J.E.6
  • 31
    • 0036783411 scopus 로고    scopus 로고
    • 3 (edelfosine), a proapoptotic agent in tumor cells
    • DOI 10.2174/1389200023337225
    • Gajate C, Mollinedo F (2002) Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells. Curr Drug Metab 3: 491-525. (Pubitemid 34987482)
    • (2002) Current Drug Metabolism , vol.3 , Issue.5 , pp. 491-525
    • Gajate, C.1    Mollinedo, F.2
  • 32
    • 0036236938 scopus 로고    scopus 로고
    • Synthesis and phospholipase C inhibitory activity of D609 diastereomers
    • Gonzalez-Roura A, Casas J, Llebaria A (2002) Synthesis and phospholipase C inhibitory activity of D609 diastereomers. Lipids 37: 401-406. (Pubitemid 34441803)
    • (2002) Lipids , vol.37 , Issue.4 , pp. 401-406
    • Gonzalez-Roura, A.1    Casas, J.2    Llebaria, A.3
  • 33
    • 0028338536 scopus 로고
    • Diversity of group types, regulation, and function of phospholipase A2
    • Dennis EA (1994) Diversity of group types, regulation, and function of phospholipase A2. J Biol Chem 269: 13057-13060.
    • (1994) J Biol Chem , vol.269 , pp. 13057-13060
    • Dennis, E.A.1
  • 34
    • 84883876868 scopus 로고    scopus 로고
    • Identifying Yersinia YopH-Targeted Signal Transduction Pathways that Impair Neutrophil Responses during In Vivo Murine Infection
    • Rolan HG, Durand EA, Mecsas J (2013) Identifying Yersinia YopH-Targeted Signal Transduction Pathways that Impair Neutrophil Responses during In Vivo Murine Infection. Cell Host Microbe 14: 306-317.
    • (2013) Cell Host Microbe , vol.14 , pp. 306-317
    • Rolan, H.G.1    Durand, E.A.2    Mecsas, J.3
  • 35
    • 0037416139 scopus 로고    scopus 로고
    • The apoptosome pathway to caspase activation in primary human neutrophils exhibits dramatically reduced requirements for cytochrome c
    • DOI 10.1084/jem.20021862
    • Murphy BM, O'Neill AJ, Adrain C, Watson RW, Martin SJ (2003) The apoptosome pathway to caspase activation in primary human neutrophils exhibits dramatically reduced requirements for cytochrome C. J Exp Med 197: 625-632. (Pubitemid 36314657)
    • (2003) Journal of Experimental Medicine , vol.197 , Issue.5 , pp. 625-632
    • Murphy, B.M.1    O'Neill, A.J.2    Adrain, C.3    Watson, R.W.G.4    Martin, S.J.5
  • 36
    • 1842333923 scopus 로고    scopus 로고
    • Augmented intracellular glutathione inhibits Fas-triggered apoptosis of activated human neutrophils
    • Watson RW, Rotstein OD, Jimenez M, Parodo J, Marshall JC (1997) Augmented intracellular glutathione inhibits Fas-triggered apoptosis of activated human neutrophils. Blood 89: 4175-4181. (Pubitemid 27220967)
    • (1997) Blood , vol.89 , Issue.11 , pp. 4175-4181
    • Watson, R.W.G.1    Rotstein, O.D.2    Jimenez, M.3    Parodo, J.4    Marshall, J.C.5
  • 37
    • 0028959195 scopus 로고
    • In vivo regulation of rat neutrophil apoptosis occurring spontaneously or induced with TNF-alpha or cycloheximide
    • Tsuchida H, Takeda Y, Takei H, Shinzawa H, Takahashi T, et al. (1995) In vivo regulation of rat neutrophil apoptosis occurring spontaneously or induced with TNF-alpha or cycloheximide. J Immunol 154: 2403-2412.
    • (1995) J Immunol , vol.154 , pp. 2403-2412
    • Tsuchida, H.1    Takeda, Y.2    Takei, H.3    Shinzawa, H.4    Takahashi, T.5
  • 39
    • 0025974730 scopus 로고
    • Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8
    • Bazzoni F, Cassatella MA, Rossi F, Ceska M, Dewald B, et al. (1991) Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8. J Exp Med 173: 771-774.
    • (1991) J Exp Med , vol.173 , pp. 771-774
    • Bazzoni, F.1    Cassatella, M.A.2    Rossi, F.3    Ceska, M.4    Dewald, B.5
  • 40
    • 33847378878 scopus 로고    scopus 로고
    • The membrane and lipids as integral participants in signal transduction: Lipid signal transduction for the non-lipid biochemist
    • Eyster KM (2007) The membrane and lipids as integral participants in signal transduction: lipid signal transduction for the non-lipid biochemist. Adv Physiol Educ 31: 5-16.
    • (2007) Adv Physiol Educ , vol.31 , pp. 5-16
    • Eyster, K.M.1
  • 41
    • 70350340575 scopus 로고    scopus 로고
    • Signaling pathways of the TREM-1- and TLR4-mediated neutrophil oxidative burst
    • Haselmayer P, Daniel M, Tertilt C, Salih HR, Stassen M, et al. (2009) Signaling pathways of the TREM-1- and TLR4-mediated neutrophil oxidative burst. J Innate Immun 1: 582-591.
    • (2009) J Innate Immun , vol.1 , pp. 582-591
    • Haselmayer, P.1    Daniel, M.2    Tertilt, C.3    Salih, H.R.4    Stassen, M.5
  • 43
    • 20444440707 scopus 로고    scopus 로고
    • Regulation of monocyte apoptosis by the protein kinase Cdelta-dependent phosphorylation of caspase-3
    • DOI 10.1074/jbc.M412449200
    • Voss OH, Kim S, Wewers MD, Doseff AI (2005) Regulation of monocyte apoptosis by the protein kinase Cdelta-dependent phosphorylation of caspase-3. J Biol Chem 280: 17371-17379. (Pubitemid 41389207)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 17371-17379
    • Voss, O.H.1    Kim, S.2    Wewers, M.D.3    Doseff, A.I.4
  • 44
    • 0036956424 scopus 로고    scopus 로고
    • Protein kinase C-epsilon (PKC-epsilon): Its unique structure and function
    • Akita Y (2002) Protein kinase C-epsilon (PKC-epsilon): its unique structure and function. J Biochem 132: 847-852.
    • (2002) J Biochem , vol.132 , pp. 847-852
    • Akita, Y.1
  • 45
    • 0036858675 scopus 로고    scopus 로고
    • Critical role of protein kinase C epsilon for lipopolysaccharide-induced IL-12 synthesis in monocyte-derived dendritic cells
    • DOI 10.1002/1521-4141(200211)32:11<3040::AID-IMMU3
    • Aksoy E, Amraoui Z, Goriely S, Goldman M, Willems F (2002) Critical role of protein kinase C epsilon for lipopolysaccharide-induced IL-12 synthesis in monocyte-derived dendritic cells. Eur J Immunol 32: 3040-3049. (Pubitemid 35414861)
    • (2002) European Journal of Immunology , vol.32 , Issue.11 , pp. 3040-3049
    • Aksoy, E.1    Amraoui, Z.2    Goriely, S.3    Goldman, M.4    Willems, F.5
  • 46
    • 0033961822 scopus 로고    scopus 로고
    • Protein kinase Cepsilon is required for the induction of mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages
    • Valledor AF, Xaus J, Comalada M, Soler C, Celada A (2000) Protein kinase C epsilon is required for the induction of mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J Immunol 164: 29-37. (Pubitemid 30012968)
    • (2000) Journal of Immunology , vol.164 , Issue.1 , pp. 29-37
    • Valledor, A.F.1    Xaus, J.2    Comalada, M.3    Soler, C.4    Celada, A.5
  • 47
    • 0034746792 scopus 로고    scopus 로고
    • Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection
    • DOI 10.1084/jem.194.9.1231
    • Castrillo A, Pennington DJ, Otto F, Parker PJ, Owen MJ, et al. (2001) Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection. J Exp Med 194: 1231-1242. (Pubitemid 33055042)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.9 , pp. 1231-1242
    • Castrillo, A.1    Pennington, D.J.2    Otto, F.3    Parker, P.J.4    Owen, M.J.5    Bosca, L.6
  • 48
    • 42449113446 scopus 로고    scopus 로고
    • The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily
    • DOI 10.1042/BJ20071348
    • Durgan J, Cameron AJ, Saurin AT, Hanrahan S, Totty N, et al. (2008) The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily. Biochem J 411: 319-331. (Pubitemid 351580184)
    • (2008) Biochemical Journal , vol.411 , Issue.2 , pp. 319-331
    • Durgan, J.1    Cameron, A.J.2    Saurin, A.T.3    Hanrahan, S.4    Totty, N.5    Messing, R.O.6    Parker, P.J.7
  • 49
    • 48649090538 scopus 로고    scopus 로고
    • The regulated assembly of a PKCepsilon complex controls the completion of cytokinesis
    • Saurin AT, Durgan J, Cameron AJ, Faisal A, Marber MS, et al. (2008) The regulated assembly of a PKCepsilon complex controls the completion of cytokinesis. Nat Cell Biol 10: 891-901.
    • (2008) Nat Cell Biol , vol.10 , pp. 891-901
    • Saurin, A.T.1    Durgan, J.2    Cameron, A.J.3    Faisal, A.4    Marber, M.S.5
  • 50
    • 49649123335 scopus 로고    scopus 로고
    • The scaffold MyD88 acts to couple protein kinase Cepsilon to Toll-like receptors
    • Faisal A, Saurin A, Gregory B, Foxwell B, Parker PJ (2008) The scaffold MyD88 acts to couple protein kinase Cepsilon to Toll-like receptors. J Biol Chem 283: 18591-18600.
    • (2008) J Biol Chem , vol.283 , pp. 18591-18600
    • Faisal, A.1    Saurin, A.2    Gregory, B.3    Foxwell, B.4    Parker, P.J.5
  • 51
    • 0034655090 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways
    • Klein JB, Rane MJ, Scherzer JA, Coxon PY, Kettritz R, et al. (2000) Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways. J Immunol 164: 4286-4291. (Pubitemid 30215090)
    • (2000) Journal of Immunology , vol.164 , Issue.8 , pp. 4286-4291
    • Klein, J.B.1    Rane, M.J.2    Scherzer, J.A.3    Coxon, P.Y.4    Kettritz, R.5    Mathiesen, J.M.6    Buridi, A.7    McLeish, K.R.8


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