Critical Role of Lyn Kinase in Inhibition of Neutrophil Apoptosis by Granulocyte-Macrophage Colony-Stimulating Factor

Journal of Immunology

Volumn 157, Issue 11, 1996, Pages 5155-5162

  Wei, Sheng ^a   Liu, Jin Hong ^a   Epling Burnette, Pearlie K ^a   Gamero, Ana M ^a   Ussery, DeWayne ^a   Pearson, Edward W ^a   Elkabani, Magda E ^a   Diaz, Jose I ^a   Djeu, Julie Y ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; HCK PROTEIN, HUMAN; HEMATOPOIETIC CELL KINASE; LYN PROTEIN-TYROSINE KINASE; ONCOPROTEIN; PROTEIN KINASE LYN; PROTEIN TYROSINE KINASE; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

APOPTOSIS; ARTICLE; CYTOLOGY; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; HUMAN; IN VITRO STUDY; METABOLISM; NEUTROPHIL; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

APOPTOSIS; BASE SEQUENCE; ENZYME ACTIVATION; GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTORS, RECOMBINANT; HUMANS; NEUTROPHILS; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-HCK; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 0030474066     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Cotter, T. G., S. V. Lennon, J. G. Glynn, and S. J. Martin. 1990. Cell death via apoptosis and its relationship to growth, development and differentiation of both tumor and normal cells. Anticancer Res. 10:1153.
2. Lloyd, A. R., and J. J. Oppenheim. 1992. Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response. Immunol. Today 13:169.
3. Craddock, C. G., S. Perry, L. E. Ventzke, and J. S. Lawrence. 1960. Evaluation of marrow granulocytic reserves in normal and disease states. Blood 15:840.
4. Colotta, F., F. Re, N. Polentarutti, S. Sozzani, and A. Mantovani. 1992. Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood 80:2012.
5. Savill, J. S., A. H. Wyllie, J. E. Henson, M. J. Walport, P. M. Henson, and C. Haslett. 1989. Macrophage phagocytosis of aging neutrophils in inflammation. J. Clin. Invest. 83:865.
6. Haslett, C. 1992. Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes. Clin. Sci. 83:639.
7. Raff, M. C. 1992. Social controls on cell survival and cell death. Nature 356:397.
8. Wyllie, A. H., J. F. Kerr, and A. R. Currie. 1980. Cell death: the significance of apoptosis. Int. Rev. Cytol. 68:251.
9. Cohen, J. J. 1993. Apoptosis. Immunol. Today 14:126.
10. Hermeking, H., and D. Eick. 1994. Mediation of c-Myc-induced apoptosis by p53. Science 265:2091.
11. Lowe, S. W., E. M. Schmitt, S. W. Smith, B. A. Osborae, and T. Jacks. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847.
12. Clarke, A. R., C. A. Purdie, D. J. Harrison, R. G. Morris, C. C. Bird, M. L. Hooper, and A. H. Wyllie. 1993. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362:849.
13. Shi, L., W. K. Nishioka, J. Th'ng, E. M. Bradbury, D. W. Litchfield, and A. H. Greenberg. 1994. Premature p34ced2 activation required for apoptosis. Science 263:1143.
14. Brunner, T., R. J. Mogil, D. LaFace, N. J. Yoo, A. Mahboubi, F. Echeverri, S. J. Martin, W. R. Force, D. H. Lynch, C. F. Ware, and D. Green. 1995. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373:441.
15. Owen-Schaub, L. B., S. Meterissian, and R. J. Ford. 1993. Fas/APO-1 expression and function on malignant cells of hematologic and nonhematologic origin. J. Immunother. 14:234.
16. Gulbins, E., R. Bissonnette, A. Mahboubi, S. Martin, W. Nishioka, T. Brunner, G. Baier, G. Baier-Bitterlich, C. Byrd, F. Lang, R. Kolesnick, A. Altman, and D. Green. 1995. FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity 2:341.
17. Dbaibo, G. S., M. Y. Pushkareva, S. Jayadev, J. K. Schwarz, J. M. Horowitz, L. M. Obeid, and Y. A. Hannun. 1995. Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest. Proc. Natl. Acad. Sci. USA 92:1347.
18. Miyashita, T., and J. C. Reed. 1992. bcl-1 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res. 52:5407.
19. Boise, L. H., M. Gonzalez-Garcia, C. E. Postema, L. Ding, T. Lindsten, L. A. Turka, X. Mao, G. Nunez, and C. B. Thompson. 1993. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597.
20. Nunez, G., L. London, D. Hockenbery, M. Alexander, J. P. McKearn, and S. J. Korsmeyer. 1990. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol 144:3602.
21. Ryan, J. J., E. Prochownik, C. A. Gottlieb, I. J. Apel, R. Merino, G. Nunez, and M. F. Clarke. 1994. c-myr and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle. Proc. Natl. Acad. Sci. USA 91:5878.
22. Djeu, J. Y., J. H. Liu, S. Wei, H. Rui, C. A. Pearson, W. J. Leonard, and D. K. Blanchard. 1993. Function associated with IL-2 receptor-β on human neutrophils. J. Immunol. 150:960.
23. Wei, S., J. H. Liu, D. K. Blanchard, and J. Y. Djeu. 1994. Induction of IL-8 gene expression in human polymorphonuclear neutrophils by recombinant IL-2. J. Immunol. 152:3630.
24. Pericle, F., J. H. Liu, J. I. Diaz, D. K. Blanchard, S. Wei, G. Forni, and J. Y. Djeu. 1994. Interleukin-2 prevention of apoptosis in human neutrophils. Eur. J. Immunol. 24:440.
25. Brach, A., S. DeVos, H. Gruss, and F. Hermann. 1992. Prolongation of survival of human polymorphonuclear neutrophils by granulocyte-macrophage colony-stimulating factor is caused by inhibition of programmed cell death. Blood 80: 2920.
26. Klebanoff, S. J., S. Olszowski, W. C. Van Voorhis, J. A. Ledbetter, A. M. Waltersdorph, and K. G. Schlechte. 1992. Effect of gamma-interferon on human neutrophils: protection from deterioration on storage. Blood 80:225.
27. Hartnell, A., A. B. Kay, and A. J. Wardlaw. 1992. IFN-γ induces expression of Fcγ FcR III (CD16) on human eosinophils. J. Immunol. 148:1471.
28. Hansell, T. T., I. J. De Vries, T. Iff, S. Rihs, M. Wandzilak, S. Beta, K. Blaser, and C. Walker. 1991. An improved immunomagnetic procedure for the isolation of highly-purified human blood eosinophils. J. Immunol. Methods 145:105.
29. Djeu, J. Y., D. Serbousek, and D. K. Blanchard. 1990. Release of tumor necrosis factor by human polymorphonuclear leukocytes. Blood 76:1405.
30. Djeu, J. Y., D. K. Blanchard, A. L. Richards, and H. Friedman. 1988. Tumor necrosis factor induction by Candida albicans from human natural killer cells and monocytes. J. Immunol. 141:4047.
31. + large granular lymphocytes and monocytes. J. Leukocyte Biol. 50:529.
32. Wei, S., J. H. Liu, D. K. Blanchard, and J. Y. Djeu. 1994. Induction of IL-8 gene expression in human polymorphonuclear neutrophils by recombinant IL-2. J. Immunol. 152:3630.
33. Boudreau, N., C. J. Sympson, Z. Werb, and M. J. Bissell. 1995. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 267:891.
34. Bolen, J. B., P. A. Thompson, E. Eiseman, and I. D. Horak. 1991. Expression and interactions of the Src family of tyrosine protein kinases in T lymphocytes. Adv. Cancer Res. 57:103.
35. Han, J. H., C. Gileadi, R. Rajapaksa, J. Kosek, and P. L. Greenberg. 1995. Modulation of apoptosis in human myeloid leukemic cells by GM-CSF. Exp. Hematol. 23:265.
36. Cox, G. 1995. Glucocorticoid treatment inhibits apoptosis in human neutrophils. J. Immunol. 154:4719.
37. Bratton, D. L., Q. Hamid, M. Boguniewicz, D. E. Doherty, J. M. Kailey, and D. Y. M. Leung. 1995. Granulocyte macrophage colony-stimulating factor contributes to enhanced monocyte survival in chronic atopic dermatitis. J. Clin. Invest. 95:221.
38. English, B. K., J. N. Ihle, A. Myracle, and T. Yi. 1993. Hck tyrosine kinase activity modulates tumor necrosis factor production by murine macrophages. J. Exp. Med. 178:1017.
39. Pazdrak, K., D. Schreiber, P. Forsythe, L. Justement, and R. Alam. 1995. The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of Lyn tyrosine kinase and the Ras-Raf-MEK-microtubule-associated protein kinase pathway. J. Exp. Med. 181:27.
40. Corey, S. J., A. L. Burkhardt, J. B. Bolen, R. L. Geahlen, L. S. Tkatch, and A. J. Tweardy. 1994. Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases. Proc. Natl. Acad. Sci. USA 91:4683.
41. Karnitz, L. M., S. L. Sutor, and T. Abraham. 1994. The src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line. J. Exp. Med. 179:1799.
42. 2 for fibroblast cell division. Science 269:1567.
43. Iwai, K., T. Miyawaki, T. Takizawa, A. Konno, K. Ohta, A. Yachie, H, Seki, and N. Taniguchi. 1994. Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils. Blood 84:1201.
44. Liles, W. C., D. C. Dale, and S. J. Klebanoff. 1994. Fas activation induces apoptosis in human phagocytes. Blood 84:371a.
45. Liles, W. C., and S. J. Klebanoff. 1995. Regulation of apoptosis in neutrophils: Fas track to death? J. Immunol. 155:3289.
46. Oltvai, Z. N., and S. J. Korsmeyer. 1994. Checkpoints of dueling dimers foil death wishes. Cell 79:189.
47. Itoh, N., Y. Tsujimoto, and S. Nagata. 1993. Effect of bcl-2 on Fas antigen-mediated cell death. J. Immunol. 151:621.
48. Haldar, S., N. Jena, and C. M. Croce. 1995. Inactivation of Bcl-2 by phosphorylation. Proc. Natl. Acad. Sci. USA 92:4507.
49. Ras in Ras induced apoptosis. J. Biol. Chem. 271:2376.
50. Takayama, S., T. Sato, S. Krajewski, K. Kochel, S. Irie, J. A. Millan, and J. C. Reed. 1995. Cloning and functional analysis of Bag-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell 80:279.
51. Miyashita, T., and J. C. Reed. 1995. Tumor suppressor p53 is a direct transcriptional activator of the human box gene. Cell 80:293.
52. Vaux, D. L., H. L. Aguila, and I. L. Weissman. 1992. Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing. Int. Immunol. 4:821.
53. Lagasse, E., and I. L. Weissman. 1994. Bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages. J. Exp. Med. 179:1047.
54. Kinoshita, T., T. Yokota, K. Arai, and A. Miyajima. 1995. Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J. 14:266.
55. Farrow, S. N., and R. Brown. 1996. New members of the Bcl-2 family and their protein partners. Curr. Opin. Genet. Dev. 6:45.
56. Li, Y., B. Shen, C. Karanes, L. Sensenbrenner, and B. Chen. 1995. Association between Lyn protein tyrosine kinase and the β subunit of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptors in a GM-CSF-dependent human megakaryocytic leukemia cell line (M-07e). J. Immunol. 155:2165.
57. Gaudry, M., C. Gilbert, F. Barabe, P. E. Poubelle, and P. H. Naccache. 1995. Activation of Lyn is a common element of the stimulation of human neutrophils by soluble and particulate agonists. Blood 86:3567.
58. Yousefi, S., D. R. Green, K. Blaser, and H. Simon. 1994. Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils. Proc. Natl. Acad. Sci. USA 91:10868.
59. Illera, V. A., C. E. Perandones, L. L. Stunz, D. A. Mower, Jr., and R. F. Ashman. 1993. Apoptosis in splenic B lymphocytes: regulation of protein kinase C and IL-4. J. Immunol. 1512:2965.
60. Walker, P. R., J. Kwast-Welfeld, H. Gourdeau, J. Leblanc, W. Neugebauer, and M. Sikorska. 1993. Relationship between apoptosis and the cell cycle in lymphocytes: roles of protein kinase C, tyrosine phosphorylation, and AP-1. Exp. Cell Res. 207:142.
61. Baxter, G. D., and M. F. Lavin. 1992. Specific protein dephosphorylation in apoptosis induced by ionizing radiation and heat shock in human lymphoid tumor lines. J. Immunol. 148:1949.
62. Fruman, D. A., P. E. Mather, S. J. Burakoff, and B. E. Bier. 1992. Correlation of calneurin phosphatase activity and programmed cell death in murine T cell hybridomas. Eur. J. Immunol. 22:2513.
63. Corey, S., A. Eguinoa, K. Puyana-Theall, J. B. Bolen, L. Cantley, F. Mollinedo, T. R. Jackson, P. T. Hawkins, and L. R. Stephens. 1993. Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3OH-kinase and src-related tyrosine kinase(s) in human myeloid derived cells. EMBO J. 12:2681.
64. Williams, G. T., C. A. Smith, E. Spooncer, T. M. Dexter, and D. R. Taylor. 1990. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 343:76.