Activity-guided isolation of NF-κB inhibitors and PPARγ agonists from the root bark of Lycium chinense Miller

Journal of Ethnopharmacology

Volumn 152, Issue 3, 2014, Pages 470-477

  Xie, Lian Wu ^a,b,d   Atanasov, Atanas G ^b   Guo, De An ^c   Malainer, Clemens ^b   Zhang, Jing Xian ^c   Zehl, Martin ^b   Guan, Shu Hong ^c   Heiss, Elke H ^b   Urban, Ernst ^b   Dirsch, Verena M ^b   Kopp, Brigitte ^b  

^a CENTRAL SOUTH UNIVERSITY OF FORESTRY AND TECHNOLOGY   (China)

^b UNIVERSITY OF VIENNA   (Austria)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^d HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Fatty acids; Lycii Radicis Cortex; Lycium chinense Miller; NF B; Phenolic amides; PPAR

Indexed keywords

1 (3,4 DIHYDROXYPHENYL) 7 HYDROXY 2 N,3 N BIS[2 (4 HYDROXYPHENYL)ETHYL] 6,8 DIMETHOXY 1,2 DIHYDRONAPHTHALENE 2,3 DICARBOXAMIDE; 2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; 2 [4,5 DIHYDROXY 2 (3 (2 (4 HYDROXYPHENYL)ETHYLAMINO) 3 OXOPROPYL)PHENYL] 3 (4 HYDROXY 3,5 DIMETHOXYPHENYL) N [2 (4 HYDROXYPHENYL)ETHYL]PROP 2 ENAMIDE; 3 N (4 ACETAMIDOBUTYL) 1 (3,4 DIHYDROXYPHENYL) 7 HYDROXY 2 N [2 (4 HYDROXYPHENYL)ETHYL] 6,8 DIMETHOXY 1,2 DIHYDRONAPHTHALENE 2,3 DICARBOXAMIDE; ACETIC ACID ETHYL ESTER; AMIDE; DICHLOROMETHANE; DIHYDRO N CAFFEOYLTYRAMINE; I KAPPA B; METHANOL; N (4 ACETAMIDOBUTYL) 2 [4,5 DIHYDROXY 2 (3 (2 (4 HYDROXYPHENYL)ETHYLAMINO) 3 OXOPROPYL)PHENYL] 3 (4 HYDROXY 3 METHOXYPHENYL)PROP 2 ENAMIDE; N (4 ACETAMIDOBUTYL) 2 [4,5 DIHYDROXY 2 (3 (2 (4 HYDROXYPHENYL)ETHYLAMINO) 3 OXOPROPYL)PHENYL] 3 (4 HYDROXY 3,5 DIMETHOXYPHENYL)PROP 2 ENAMIDE; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PHENOL DERIVATIVE; TRANS N (P COUMAROYL)TYRAMINE; TRANS N CAFFEOYLTYRAMINE; TRANS N FERULOYLTYRAMINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; FATTY ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLANT EXTRACT;

ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; FRACTIONATION; IC 50; IN VITRO STUDY; LYCIUM CHINENSE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; AGONISTS; ANTAGONISTS AND INHIBITORS; BARK; CHEMISTRY; CHINESE MEDICINE; HUMAN; IC50; ISOLATION AND PURIFICATION; LYCIUM; STRUCTURE ACTIVITY RELATION;

LYCIUM CHINENSE;

AMIDES; FATTY ACIDS; HUMANS; INHIBITORY CONCENTRATION 50; LYCIUM; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MEDICINE, CHINESE TRADITIONAL; NF-KAPPA B; PHENOLS; PLANT BARK; PLANT EXTRACTS; PLANT ROOTS; PPAR GAMMA; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84900359212     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.01.029     Document Type: Article

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