Hesperetin inhibits rat coronary constriction by inhibiting Ca2+ influx and enhancing voltage-gated K+ channel currents of the myocytes

European Journal of Pharmacology

Volumn 735, Issue 1, 2014, Pages 193-201

  Liu, Yu ^a   Niu, Longgang ^a   Cui, Lijuan ^a   Hou, Xiaomin ^a   Li, Jiangtao ^a   Zhang, Xuanping ^a   Zhang, Mingsheng ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

Coronary artery; Hesperetin; L type voltage gated calcium channels; Vasorelaxation; Voltage gated potassium channels

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 4 AMINOPYRIDINE; BARIUM CHLORIDE; CALCIUM ION; ESTER DERIVATIVE; GLIBENCLAMIDE; HESPERETIN; IBERIOTOXIN; INDOMETACIN; NG NITRO LEVO ARGININE METHYLESTER ESTER; POTASSIUM CHLORIDE; UNCLASSIFIED DRUG; VASOCONSTRICTOR AGENT; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; CALCIUM; HESPERIDIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL FUNCTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORONARY ARTERY CONSTRICTION; CORONARY ARTERY DILATATION; ELECTROMYOGRAPHY; ENDOTHELIUM DENUDATION; EXTRACELLULAR CALCIUM; HEART MUSCLE CELL; MALE; MOLECULAR PROBE; MUSCLE DEVELOPMENT; NONHUMAN; PATCH CLAMP TECHNIQUE; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SPASMOLYSIS; VASCULAR SMOOTH MUSCLE; ANIMAL; CORONARY BLOOD VESSEL; DRUG EFFECTS; HEART CONTRACTION; IN VITRO STUDY; METABOLISM; PHYSIOLOGY; SMOOTH MUSCLE FIBER; VASOCONSTRICTION; WISTAR RAT;

ANIMALS; CALCIUM; CORONARY VESSELS; HESPERIDIN; IN VITRO TECHNIQUES; MALE; MYOCARDIAL CONTRACTION; MYOCYTES, SMOOTH MUSCLE; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS, WISTAR; VASOCONSTRICTION;

EID: 84900353956     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.03.057     Document Type: Article

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