Baicalein inhibits interleukin-1β-induced proliferation of human rheumatoid arthritis fibroblast-like synoviocytes

Inflammation

Volumn 37, Issue 1, 2014, Pages 163-169

  Chen, Shuo ^a   Yang, Yang ^a   Feng, Hui ^a   Wang, Hehong ^a   Zhao, Riguang ^a   Liu, Hongbin ^a  

^a 97th Hospital of PLA   (China)

Author keywords

Interleukin 1 Beta (IL 1 ); Macrophage Migration Inhibitory Factory (MIF); Mitogen Activated Protein Kinase (MAPK); Nuclear Factor Kappa B (NF B); Rheumatoid Arthritis Fibroblast Like Synoviocytes (RAFLS)

Indexed keywords

BAICALEIN; INTERLEUKIN 1BETA; MACROPHAGE MIGRATION INHIBITION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; THYMIDINE; TRANSCRIPTION FACTOR RELA;

ANALYSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; ENZYME PHOSPHORYLATION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; ARTHRITIS, RHEUMATOID; CELL PROLIFERATION; CELLS, CULTURED; DNA-BINDING PROTEINS; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; FLAVANONES; HUMANS; INTERLEUKIN-1BETA; INTRAMOLECULAR OXIDOREDUCTASES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BINDING; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; TRANSCRIPTION FACTOR RELA;

EID: 84900351677     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-013-9725-9     Document Type: Article

References (30)

1. Li, H., and A. Wan. 2013. Apoptosis of rheumatoid arthritis fibroblast-like synoviocytes: possible roles of nitric oxide and the thioredoxin 1. Mediators of Inflammation 2013: 953462.
2. Han, M.K., J.S. Kim, B.H. Park, J.R. Kim, B.Y. Hwang, H.Y. Lee, E.K. Song, and W.H. Yoo. 2003. NF-kappaB-dependent lymphocyte hyper adhesiveness to synovial fi broblasts by hypoxia and reoxygenation: potential role in rheumatoid arthritis. Journal of Leukocyte Biology 73: 525-529.
3. Firestein, G.S. 1996. Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors? Arthritis and Rheumatism 39: 1781-1790. (Pubitemid 26378569)
4. Firestein, G.S., M. Yeo, and N.J. Zvaifl er. 1995. Apoptosis in rheumatoid arthritis synovium. Journal of Clinical Investigation 96: 1631-1638.
5. Choy, E.H., and G.S. Panayi. 2001. Cytokine pathways and joint inflammation in rheumatoid arthritis. The New England Journal of Medicine 344: 907-916. (Pubitemid 32224400)
6. Lacey, D., A. Sampey, R. Mitchell, R. Bucala, L. Santos, M. Leech, and E. Morand. 2003. Control of fibroblast-like synoviocyte proliferation by macrophage migration inhibitory factor. Arthritis and Rheumatism 48: 103-109. (Pubitemid 36091654)
7. Ayoub, S., M.J. Hickey, and E.F. Morand. 2008. Mechanisms of disease: macrophage migration inhibitory factor in SLE, RA and atherosclerosis. Nature Clinical Practice Rheumatology 4: 98-105. (Pubitemid 351217659)
8. So, F.V., N. Guthrie, A.F. Chambers, and K.K. Carroll. 1997. Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen. Cancer Letters 112: 127-133. (Pubitemid 27104286)
9. Lin, C.C., and D.E. Shieh. 1996. The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin. The American Journal of Chinese Medicine 24: 31-36.
10. Wong, B.C., W.P.Wang, C.H. Cho, X.M. Fan, M.C. Lin, H.F. Kung, and S.K. Lam. 2001. 12-Lipoxygenase inhibition induced apoptosis in human gastric cancer cells. Carcinogenesis 22: 1349-1354. (Pubitemid 32898689)
11. Chen, J., Z. Li, A.Y. Chen, X. Ye, H. Luo, G.O. Rankin, and Y.C. Chen. 2013. Inhibitory effect of baicalin and baicalein on ovarian cancer cells. International Journal of Molecular Sciences 14: 6012-6025.
12. Zhang, H.B., P. Lu, Q.Y. Guo, Z.H. Zhang, and X.Y. Meng. 2013. Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway. Oncology Letters 5: 722-728.
13. Yang, J.H., M.Y. Yun, N.H. Lee, D.K. Kim, Y.I. Kim, Y.H. Noh, T.Y. Kim, S.W. Yoon, and S.C. Shin. 2008. The effects of ketorolac tromethamine and baicalein on the levels of inflammatory factors in human synoviocytes. Archives of Pharmacal Research 31: 1517-1523.
14. Arnett, F.C., S.M. Edworthy, D.A. Bloch, D.J. McShane, J.F. Fries, N.S. Cooper, L.A. Healey, S.R. Kaplan, M.H. Liang, H.S. Luthra, et al. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis and Rheumatism 31: 315-324. (Pubitemid 18091653)
15. Lee, H.Y., H.S. Jeon, E.K. Song, M.K. Han, S.I. Park, S.I. Lee, H.J. Yun, J.R. Kim, J.S. Kim, Y.C. Lee, S.I. Kim, H.R. Kim, J.Y. Choi, I. Kang, H.Y. Kim, and W.H. Yoo. 2006. CD40 ligation of rheumatoid synovial fibroblasts regulates RANKL-mediated osteoclastogenesis: evidence of NF-kappaB-dependent, CD40-mediated bone destruction in rheumatoid arthritis. Arthritis and Rheumatism 54: 1747-1758. (Pubitemid 43877924)
16. Noh, E.M., J.S. Kim, H. Hur, B.H. Park, E.K. Song, M.K. Han, K.B. Kwon, W.H. Yoo, I.K. Shim, S.J. Lee, H.J. Youn, and Y.R. Lee. 2009. Cordycepin inhibits IL-1beta-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. Rheumatology (Oxford, England) 48: 45-48.
17. Gitter, B.D., J.M. Labus, S.L. Lees, and M.E. Scheetz. 1989. Characteristics of human synovial fibroblast activation by IL-1 beta and TNF alpha. Immunology 66: 196-200. (Pubitemid 19065793)
18. Symons, J.A., T.L. McDowell, F.S. di Giovine, N.C. Wood, S.J. Capper, and G.W. Duff. 1989. Interleukin 1 in rheumatoid arthritis: potentiation of immune responses within the joint. Lymphokine Research 8: 365-372. (Pubitemid 19215549)
19. Williams, A.S., S.G. Jones, R.M. Goodfellow, N. Amos, and B.D. Williams. 1999. Interleukin-1beta (IL-1beta) inhibition: a possible mechanism for the anti-in flammatory potency of liposomally conjugated methotrexate formulations in arthritis. British Journal of Pharmacology 128: 234-240. (Pubitemid 29425290)
20. Geiger, T., H. Towbin, A. Cosenti-Vargas, O. Zingel, J. Arnold, C. Rordorf, M. Glatt, and K. Vosbeck. 1993. Neutralization of interleukin-1 beta activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase response. Clinical and Experimental Rheumatology 11: 515-522. (Pubitemid 23328815)
21. Van den BERG, W.B., L.A.B. JOOSTEN, M. HELSEN, and F.A.J. Van de LOO. 1994. Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment. Clinical and Experimental Immunology 95: 237-243.
22. Lee, E.G., S.L. Lee, H.J. Chae, S.J. Park, Y.C. Lee, and W.H. Yoo. 2010. Ethyl acetate fraction from Cudrania tricuspidata inhibits IL-1β-induced rheumatoid synovial fibroblast proliferation and MMPs, COX-2 and PGE2 production. Biological Research 43: 225-231.
23. Inoue, H., M. Takamori, N. Nagata, T. Nishikawa, H. Oda, S. Yamamoto, and Y. Koshihara. 2001. An investigation of cell proliferation and soluble mediators induced by interleukin 1beta in human synovial fibroblasts: comparative response in osteoarthritis and rheumatoid arthritis. Inflammation Research 50: 65-72. (Pubitemid 32210146)
24. McIntyre, K.W., D.J. Shuster, K.M. Gillooly, D.M. Dambach, M.A. Pattoli, P. Lu, X.D. Zhou, Y. Qiu, F.C. Zusi, and J.R. Burke. 2003. A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint in fl ammation and destruction in collagen-induced arthritis in mice. Arthritis and Rheumatism 48: 2652-2659. (Pubitemid 37129443)
25. Robinson, M.J., and M.H. Cobb. 1997. Mitogen-activated protein kinase pathways. Current Opinion in Cell Biology 9: 180-185.
26. Han, Z., D.L. Boyle, L. Chang, B. Bennett, M. Karin, L. Yang, A.M. Manning, and G.S. Firestein. 2001. c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. Journal of Clinical Investigation 108(1): 73-81. Erratum in: J. Clin. Invest. 108:1883. (Pubitemid 32634924)
27. Nishikawa, M., A. Myoui, T. Tomita, K. Takahi, A. Nampei, and H. Yoshikawa. 2003. Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653. Arthritis and Rheumatism 48: 2670-2681. (Pubitemid 37129445)
28. Han, Z., D.L. Boyle, A.M. Manning, and G.S. Firestein. 1998. AP-1 and NF-kB regulation in rheumatoid arthritis and murine collagen-induced arthritis. Autoimmunity 28: 197-208. (Pubitemid 29027651)
29. Youn, J., H.Y. Kim, J.H. Park, S.H. Hwang, S.Y. Lee, C.S. Cho, and S.K. Lee. 2002. Regulation of TNF-alpha-mediated hyperplasia through TNF receptors, TRAFs, and NF-kappaB in synoviocytes obtained from patients with rheumatoid arthritis. Immunology Letters 83: 85-93. (Pubitemid 34626941)
30. Huber, L.C., O. Distler, I. Tarner, R.E. Gay, S. Gay, and T. Pap. 2006. Synovial fibroblasts: key players in rheumatoid arthritis. Rheumatology (Oxford, England) 45: 669-675. (Pubitemid 43985334)