NF-κB-dependent lymphocyte hyperadhesiveness to synovial fibroblasts by hypoxia and reoxygenation: Potential role in rheumatoid arthritis

Journal of Leukocyte Biology

Volumn 73, Issue 4, 2003, Pages 525-529

  Han, Myung Kwan ^a   Kim, Jong Suk ^a   Park, Byung Hyun ^a   Kim, Jung Ryul ^a   Hwang, Byung Yun ^a   Lee, Hak Yong ^a   Song, Eun Kyung ^a   Yoo, Wan Hee ^a  

^a Chonbuk National University Medical School   (South Korea)

Author keywords

Adhesion; Synovial fibroblasts

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; PHORBOL 12 ACETATE 13 MYRISTATE; PYRROLIDINE DITHIOCARBAMATE; ANTIOXIDANT; CARCINOGEN; MESSENGER RNA; OXYGEN; PHORBOL 13 ACETATE 12 MYRISTATE; PRIMER DNA; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; THIOCARBAMIC ACID DERIVATIVE;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HYPOXIA; INFLAMMATORY CELL; LYMPHOCYTE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; RHEUMATOID ARTHRITIS; SYNOVIUM; CELL ADHESION; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; FLOW CYTOMETRY; GENETICS; METABOLISM; PHYSIOLOGY; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANTIOXIDANTS; ARTHRITIS, RHEUMATOID; BLOTTING, WESTERN; CARCINOGENS; CELL ADHESION; CELLS, CULTURED; DNA PRIMERS; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTES; NF-KAPPA B; OXYGEN; PYRROLIDINES; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYNOVIAL MEMBRANE; TETRADECANOYLPHORBOL ACETATE; THIOCARBAMATES; UP-REGULATION;

EID: 0038659368     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0502256     Document Type: Article

References (34)

1. Bodamyali, T., Stevens, C. R., Billingham, M. E., Ohta, S., Blake, D. R. (1998) Influence of hypoxia in inflammatory synovitis. Ann. Rheum. Dis. 57, 703-710.
2. Mapp, P. I., Grootveld, M. C., Blake, D. R. (1995) Hypoxia, oxidative stress and rheumatoid arthritis. Br. Med. Bull. 51, 419-436.
3. Blake, D. R., Winyard, P. G., Marok, R. (1994) The contribution of hypoxia/reperfusion injury to inflammatory synovitis: the influence of reactive oxygen intermediates on the transcriptional control of inflammation. Ann. N. Y. Acad. Sci. 723, 308-317.
4. Stevens, C. R., Blake, D. R., Merry, P., Revell, P. A., Levick, J. R. (1991) A comparative study by morphometry of the microvasculature in normal and rheumatoid synovium. Arthritis Rheum. 34, 1508-1513.
5. Allen, R. E., Blake, D. R., Nazhat, N. B., Jones, P. (1989) Superoxide radical generation by inflamed human synovium after hypoxia. Lancet 2, 282-283.
6. Tak, P. P., Zvaifler, N. J., Green, D. R., Firestein, G. S. (2000) Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases. Immunol. Today 21, 78-82.
7. Miesel, R., Murphy, M. P., Kroger, H. (1996) Enhanced mitochondrial radical production in patients which rheumatoid arthritis correlates with elevated levels of tumor necrosis factor alpha in plasma. Free Radic. Res. 25, 161-169.
8. Jikimoto, T., Nishikubo, Y., Koshiba, M., Kanagawa, S., Morinobu, S., Morinobu, A., Saura, R., Mizuno, K., Kondo, S., Toyokuni, S., et al. (2002) Thioredoxin as a biomarker for oxidative stress in patients with rheumatoid arthritis. Mol. Immunol. 38, 765-772.
9. Ghezzi, P., Dinarello, C. A., Bianchi, M., Rosandich, M. E., Repine, J. E., White, C. W. (1991) Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells. Cytokine 3, 189-194.
10. Hempel, S. L., Monick, M. M., Hunninghake, G. W. (1996) Effect of hypoxia on release of IL-1 and TNF by human alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 14, 170-176.
11. Maini, R. N., Taylor, P. C. (2000) Anti-cytokine therapy for rheumatoid arthritis. Annu. Rev. Med. 51, 207-229
12. Smith, R. S., Smith, T. J., Blieden, T. M., Phipps, R. P. (1997) Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation. Am. J. Pathol. 151, 317-322.
13. Panayi, G. S., Lanchbury, J. S., Kingsley, G. H. (1992) The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum. 35, 729-735.
14. Cavender, D., Haskard, D., Yu, C. L., Iguchi, T., Miossec, P., Oppenheimer-Marks, N., Ziff, M. (1987) Pathways to chronic inflammation in rheumatoid synovitis. Fed. Proc. 46, 113-117.
15. Sewell, K. L., Trentham, D. E. (1993) Pathogenesis of rheumatoid arthritis. Lancet 341, 283-286.
16. Kunkel, S. L., Lukacs, N., Kasama, T., Strieter, R. M. (1996) The role of chemokines in inflammatory joint disease. J. Leukoc. Biol. 59, 6-12.
17. Buras, J. A., Stahl, G. L., Svoboda, K. K., Reenstra, W. R. (2000) Hyperbaric oxygen downregulates ICAM-1 expression induced by hypoxia and hypoglycemia: the role of NOS. Am. J. Physiol. Cell Physiol. 278, C292-C302.
18. Matsuoka, N., Eguchi, K., Kawakami, A., Ida, H., Nakashima, M., Sakai, M., Terada, K., Inoue, S., Kawabe, Y., Kurata, A., et al. (1991) Phenotypic characteristics of T cells interacted with synovial cells. J. Rheumatol. 18, 1137-1142.
19. Rosengard, B. R., Cochrane, D. E. (1983) Complement-mediated cytolysis: a quick, simple method for determining levels of immunoglobulin E bound to mast cells. J. Histochem. Cytochem. 31, 441-444.
20. Matsuoka, N., Eguchi, K., Kawakami, A., Ida, H., Nakashima, M., Sakai, M., Terada, K., Inoue, S., Kawabe, Y., Kurata, A., et al. (1991) Phenotypic characteristics of T cells interacted with synovial cells. J. Rheumatol. 18, 1137-1142.
21. Ross, S. D., Kron, I. L., Gangemi, J. J., Shockey, K. S., Stoler, M., Kern, J. A., Tribble, C. G., Laubach, V. E. (2000) Attenuation of lung reperfusion injury after transplantation using an inhibitor of nuclear factor-kappaB. Am. J. Physiol. Lung Cell. Mol. Physiol. 279, L528-L536.
22. Tak, P. P., Gerlag, D. M., Aupperle, K. R., van de Geest, D. A., Overbeek, M., Bennett, B. L., Boyle, D. L., Manning, A. M., Firestein, G. S. (2001) Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation. Arthritis Rheum. 44, 1897-1907.
23. Lipsky, P. E., van der Heijde, D. M., St Clair, E. W., Furst, D. E., Breedveld, F. C., Kalden, J. R., Smolen, J. S., Weisman, M., Emery, P., Feldmann, M., Harriman, G. R., Maini, R. N. (2000) Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N. Engl. J. Med. 343, 1594-1602.
24. Furst, D. E., Breedveld, F. C., Burmester, G. R., Crofford, J. J., Emery, P., Feldmann, M., Kalden, J. R., Kavanaugh, A. F., Keystone, E. C., Klareskog, L. G., Lipsky, P. E., Maini, R. N., Russell, A. S., Scott, D. L., Smolen, J. S., Van de Putte, L. B., Visher, T. L., Weisman, M. H. (2000) Updated consensus statement on tumour necrosis factor blocking agents for the treatment of rheumatoid arthritis (May 2000). Ann. Rheum. Dis. 59 (Suppl. 1), i1-i2.
25. Aupperle, K., Bennett, B., Han, Z., Boyle, D., Manning, A., Firestein, G. (2001) NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes. J. Immunol. 166, 2705-2711.
26. Schreck, R., Rieber, P., Baeuerle, P. A. (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 10, 2247-2258.
27. Flohe, L., Brigelius-Flohe, R., Saliou, C., Traber, M. G., Packer, L. (1997) Redox regulation of NF-kappa B activation. Free Radic. Biol. Med. 22, 1115-1126.
28. Makarov, S. S. (2001) NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction. Arthritis Res. 3, 200-206.
29. Miagkov, A. V., Kovalenko, D. V., Brown, C. E., Didsbury, J. R., Cogswell, J. P., Stimpson, S. A., Baldwin, A. S., Makarov, S. S. (1998) NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint. Proc. Natl. Acad. Sci. USA 95, 13859-13864.
30. Howard, E. F., Chen, Q., Cheng, C., Carroll, J. E., Hess, D. (1998) NF-kappa B is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells. Neurosci. Lett. 248, 199-203.
31. Oppenheimer-Marks, N., Davis, L. S., Bogue, D. T., Ramberg, J., Lipsky, P. E. (1991) Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytes. J. Immunol. 147, 2913-2921.
32. Chin, J. E., Winterrowd, G. E., Krzesicki, R. F., Sanders, M. E. (1990) Role of cytokines in inflammatory synovitis. The coordinate regulation of intercellular adhesion molecule 1 and HLA class I and class II antigens in rheumatoid synovial fibroblasts. Arthritis Rheum. 33, 1776-1786.
33. Aupperle, K. R., Yamanishi, Y., Bennett, B. L., Mercurio, F., Boyle, D. L., Firestein, G. S. (2001) Expression and regulation of inducible IkappaB kinase (IKK-i) in human fibroblast-like synoviocytes. Cell. Immunol. 214, 54-59.
34. Wahid, S., Blades, M. C., De Lord, D., Brown, I., Blake, G., Yanni, G., Haskard, D. O., Panayi, G. S., Pitzalis, C. (2000) Tumour necrosis factor-alpha (TNF-alpha) enhances lymphocyte migration into rheumatoid synovial tissue transplanted into severe combined immunodeficient (SCID) mice. Clin. Exp. Immunol. 122, 133-142.