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Volumn 154, Issue 1, 2014, Pages 156-162

An-Gong-Niu-Huang Wan protects against cerebral ischemia induced apoptosis in rats: Up-regulation of Bcl-2 and down-regulation of Bax and caspase-3

Author keywords

An Gong Niu Huang Wan; Apoptosis; Cerebral ischemia; Traditional Chinese medicine

Indexed keywords

AN GONG NIU HUANG; CASPASE 3; DNA; HERBACEOUS AGENT; NEUROPROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; TETRAZOLIUM; UNCLASSIFIED DRUG; AN-GONG-NIU-HUANG WAN; CASP3 PROTEIN, RAT;

EID: 84900320439     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.03.057     Document Type: Article
Times cited : (62)

References (39)
  • 1
    • 0028941909 scopus 로고
    • Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: Evidence for apoptosis during selective neuronal loss
    • E.J. Beilharz, C.E. Williams, M. Dragunow, E.S. Sirimanne, and P.D. Gluckman Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: evidence for apoptosis during selective neuronal loss Brain Research Molecular Brain Research 29 1995 1 14
    • (1995) Brain Research Molecular Brain Research , vol.29 , pp. 1-14
    • Beilharz, E.J.1    Williams, C.E.2    Dragunow, M.3    Sirimanne, E.S.4    Gluckman, P.D.5
  • 3
    • 65549098614 scopus 로고    scopus 로고
    • Apoptotic mechanisms after cerebral ischemia
    • B.R. Broughton, D.C. Reutens, and C.G. Sobey Apoptotic mechanisms after cerebral ischemia Stroke 40 2009 e331 e339
    • (2009) Stroke , vol.40
    • Broughton, B.R.1    Reutens, D.C.2    Sobey, C.G.3
  • 4
    • 38849204371 scopus 로고    scopus 로고
    • The protective effects of in vitro cultivated calculus bovis on the cerebral and myocardial cells in hypoxic mice
    • H. Cai, Y. Guang, and L. Liu The protective effects of in vitro cultivated calculus bovis on the cerebral and myocardial cells in hypoxic mice Journal of Huazhong University of Science and Technology Medical Sciences 27 2007 635 638
    • (2007) Journal of Huazhong University of Science and Technology Medical Sciences , vol.27 , pp. 635-638
    • Cai, H.1    Guang, Y.2    Liu, L.3
  • 5
    • 0032124903 scopus 로고    scopus 로고
    • Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia
    • J. Chen, T. Nagayama, K. Jin, R.A. Stetler, R.L. Zhu, S.H. Graham, and R.P. Simon Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia Journal of Neuroscience 18 1998 4914 4928
    • (1998) Journal of Neuroscience , vol.18 , pp. 4914-4928
    • Chen, J.1    Nagayama, T.2    Jin, K.3    Stetler, R.A.4    Zhu, R.L.5    Graham, S.H.6    Simon, R.P.7
  • 7
    • 0037384802 scopus 로고    scopus 로고
    • Signaling of cell death and cell survival following focal cerebral ischemia: Life and death struggle in the penumbra
    • I. Ferrer, and A.M. Planas Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra Journal of Neuropathology & Experimental Neurology 62 2003 329 339
    • (2003) Journal of Neuropathology & Experimental Neurology , vol.62 , pp. 329-339
    • Ferrer, I.1    Planas, A.M.2
  • 8
    • 0348048849 scopus 로고    scopus 로고
    • The ischemic penumbra: Identification, evolution and treatment concepts
    • M. Fisher The ischemic penumbra: identification, evolution and treatment concepts Cerebrovascular Diseases 17 Suppl. 1 2004 1 6
    • (2004) Cerebrovascular Diseases , vol.17 , Issue.SUPPL.. 1 , pp. 1-6
    • Fisher, M.1
  • 12
  • 13
    • 0031816414 scopus 로고    scopus 로고
    • Apoptosis, excitotoxicity, and neuropathology
    • M. Leist, and P. Nicotera Apoptosis, excitotoxicity, and neuropathology Experimental Cell Research 239 1998 183 201
    • (1998) Experimental Cell Research , vol.239 , pp. 183-201
    • Leist, M.1    Nicotera, P.2
  • 14
    • 81955167409 scopus 로고    scopus 로고
    • Lutein enhances survival and reduces neuronal damage in a mouse model of ischemic stroke
    • S.Y. Li, D. Yang, Z.J. Fu, T. Woo, D. Wong, and A.C. Lo Lutein enhances survival and reduces neuronal damage in a mouse model of ischemic stroke Neurobiology of Disease 45 2012 624 632
    • (2012) Neurobiology of Disease , vol.45 , pp. 624-632
    • Li, S.Y.1    Yang, D.2    Fu, Z.J.3    Woo, T.4    Wong, D.5    Lo, A.C.6
  • 15
    • 76749114801 scopus 로고    scopus 로고
    • Effects of in vitro cultivated calculus Bovis compound on pulmonary lesions in rabbits with schistosomiasis
    • T. Li, Z. Yang, H.J. Cai, L.W. Song, K.Y. Lu, Z. Zhou, and Z.D. Wu Effects of in vitro cultivated calculus Bovis compound on pulmonary lesions in rabbits with schistosomiasis World Journal of Gastroenterology 16 2010 749 754
    • (2010) World Journal of Gastroenterology , vol.16 , pp. 749-754
    • Li, T.1    Yang, Z.2    Cai, H.J.3    Song, L.W.4    Lu, K.Y.5    Zhou, Z.6    Wu, Z.D.7
  • 16
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • P. Lipton Ischemic cell death in brain neurons Physiological Reviews 79 1999 1431 1568
    • (1999) Physiological Reviews , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 17
    • 77951689205 scopus 로고    scopus 로고
    • Antipyretic and antioxidant activities of the aqueous extract of Cornu bubali (water buffalo horn)
    • R. Liu, M. Wang, and J.A. Duan Antipyretic and antioxidant activities of the aqueous extract of Cornu bubali (water buffalo horn) American Journal of Chinese Medicine 38 2010 293 306
    • (2010) American Journal of Chinese Medicine , vol.38 , pp. 293-306
    • Liu, R.1    Wang, M.2    Duan, J.A.3
  • 18
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • E.Z. Longa, P.R. Weinstein, S. Carlson, and R. Cummins Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84 91
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 19
    • 79251616306 scopus 로고    scopus 로고
    • Realgar- and cinnabar-containing An-Gong-Niu-Huang Wan (AGNH) is much less acutely toxic than sodium arsenite and mercuric chloride
    • Y.F. Lu, J.W. Yan, Q. Wu, J.Z. Shi, J. Liu, and J.S. Shi Realgar- and cinnabar-containing An-Gong-Niu-Huang Wan (AGNH) is much less acutely toxic than sodium arsenite and mercuric chloride Chemico-Biological Interactions 189 2011 134 140
    • (2011) Chemico-Biological Interactions , vol.189 , pp. 134-140
    • Lu, Y.F.1    Yan, J.W.2    Wu, Q.3    Shi, J.Z.4    Liu, J.5    Shi, J.S.6
  • 21
  • 24
    • 4544298249 scopus 로고    scopus 로고
    • Mitochondrial mechanisms of neural cell apoptosis
    • B.M. Polster, and G. Fiskum Mitochondrial mechanisms of neural cell apoptosis Journal of Neurochemistry 90 2004 1281 1289
    • (2004) Journal of Neurochemistry , vol.90 , pp. 1281-1289
    • Polster, B.M.1    Fiskum, G.2
  • 27
    • 0032918137 scopus 로고    scopus 로고
    • Caspases as treatment targets in stroke and neurodegenerative diseases
    • J.B. Schulz, M. Weller, and M.A. Moskowitz Caspases as treatment targets in stroke and neurodegenerative diseases Annals of Neurology 45 1999 421 429
    • (1999) Annals of Neurology , vol.45 , pp. 421-429
    • Schulz, J.B.1    Weller, M.2    Moskowitz, M.A.3
  • 29
    • 0030820028 scopus 로고    scopus 로고
    • Systematic review of evidence on thrombolytic therapy for acute ischaemic stroke
    • J.M. Wardlaw, C.P. Warlow, and C. Counsell Systematic review of evidence on thrombolytic therapy for acute ischaemic stroke Lancet 350 1997 607 614
    • (1997) Lancet , vol.350 , pp. 607-614
    • Wardlaw, J.M.1    Warlow, C.P.2    Counsell, C.3
  • 30
    • 77955329651 scopus 로고    scopus 로고
    • Chinese medicine Nao-Shuan-Tong attenuates cerebral ischemic injury by inhibiting apoptosis in a rat model of stroke
    • J. Xiang, Y.P. Tang, P. Wu, J.P. Gao, and D.F. Cai Chinese medicine Nao-Shuan-Tong attenuates cerebral ischemic injury by inhibiting apoptosis in a rat model of stroke Journal of Ethnopharmacology 131 2010 174 181
    • (2010) Journal of Ethnopharmacology , vol.131 , pp. 174-181
    • Xiang, J.1    Tang, Y.P.2    Wu, P.3    Gao, J.P.4    Cai, D.F.5
  • 31
    • 79952199212 scopus 로고    scopus 로고
    • Apocynum venetum leaf extract protects rat cortical neurons from injury induced by oxygen and glucose deprivation in vitro
    • J. Xiang, Y.P. Tang, Z.Y. Zhou, P. Wu, Z. Wang, M. Mori, and D.F. Cai Apocynum venetum leaf extract protects rat cortical neurons from injury induced by oxygen and glucose deprivation in vitro Canadian Journal of Physiology and Pharmacology 88 2010 907 917
    • (2010) Canadian Journal of Physiology and Pharmacology , vol.88 , pp. 907-917
    • Xiang, J.1    Tang, Y.P.2    Zhou, Z.Y.3    Wu, P.4    Wang, Z.5    Mori, M.6    Cai, D.F.7
  • 33
    • 5044227407 scopus 로고    scopus 로고
    • Ischemia and ischemic tolerance in the brain: An overview
    • D. Zemke, J.L. Smith, M.J. Reeves, and A. Majid Ischemia and ischemic tolerance in the brain: an overview Neurotoxicology 25 2004 895 904
    • (2004) Neurotoxicology , vol.25 , pp. 895-904
    • Zemke, D.1    Smith, J.L.2    Reeves, M.J.3    Majid, A.4
  • 34
    • 0035012926 scopus 로고    scopus 로고
    • Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c from mitochondria in a rat forebrain ischemia model
    • R.Z. Zhan, C. Wu, H. Fujihara, K. Taga, S. Qi, M. Naito, and K. Shimoji Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c From mitochondria in a rat forebrain ischemia model Journal of Cerebral Blood Flow & Metabolism 21 2001 529 540
    • (2001) Journal of Cerebral Blood Flow & Metabolism , vol.21 , pp. 529-540
    • Zhan, R.Z.1    Wu, C.2    Fujihara, H.3    Taga, K.4    Qi, S.5    Naito, M.6    Shimoji, K.7
  • 35
    • 84861228539 scopus 로고    scopus 로고
    • Neuroprotection of early and short-time applying berberine in the acute phase of cerebral ischemia: Up-regulated pAkt, pGSK and pCREB, down-regulated NF-kappaB expression, ameliorated BBB permeability
    • X. Zhang, X. Zhang, C. Wang, Y. Li, L. Dong, L. Cui, L. Wang, Z. Liu, H. Qiao, C. Zhu, Y. Xing, X. Cao, Y. Ji, and K. Zhao Neuroprotection of early and short-time applying berberine in the acute phase of cerebral ischemia: up-regulated pAkt, pGSK and pCREB, down-regulated NF-kappaB expression, ameliorated BBB permeability Brain Research 1459 2012 61 70
    • (2012) Brain Research , vol.1459 , pp. 61-70
    • Zhang, X.1    Zhang, X.2    Wang, C.3    Li, Y.4    Dong, L.5    Cui, L.6    Wang, L.7    Liu, Z.8    Qiao, H.9    Zhu, C.10    Xing, Y.11    Cao, X.12    Ji, Y.13    Zhao, K.14
  • 36
    • 0038587580 scopus 로고    scopus 로고
    • Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity
    • H. Zhao, M.A. Yenari, D. Cheng, R.M. Sapolsky, and G.K. Steinberg Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity Journal of Neurochemistry 85 2003 1026 1036
    • (2003) Journal of Neurochemistry , vol.85 , pp. 1026-1036
    • Zhao, H.1    Yenari, M.A.2    Cheng, D.3    Sapolsky, R.M.4    Steinberg, G.K.5
  • 37
    • 80054969251 scopus 로고    scopus 로고
    • Neuroprotection against excitotoxic and ischemic insults by bis(12)-hupyridone, a novel anti-acetylcholinesterase dimer, possibly via acting on multiple targets
    • Y. Zhao, J. Dou, J. Luo, W. Li, H.H. Chan, W. Cui, H. Zhang, R. Han, P.R. Carlier, X. Zhang, and Y. Han Neuroprotection against excitotoxic and ischemic insults by bis(12)-hupyridone, a novel anti-acetylcholinesterase dimer, possibly via acting on multiple targets Brain Research 1421 2011 100 109
    • (2011) Brain Research , vol.1421 , pp. 100-109
    • Zhao, Y.1    Dou, J.2    Luo, J.3    Li, W.4    Chan, H.H.5    Cui, W.6    Zhang, H.7    Han, R.8    Carlier, P.R.9    Zhang, X.10    Han, Y.11
  • 38
    • 80053376294 scopus 로고    scopus 로고
    • Delayed ischemic postconditioning protects hippocampal CA1 neurons by preserving mitochondrial integrity via Akt/GSK3beta signaling
    • C. Zhou, J. Tu, Q. Zhang, D. Lu, Y. Zhu, W. Zhang, F. Yang, D.W. Brann, and R. Wang Delayed ischemic postconditioning protects hippocampal CA1 neurons by preserving mitochondrial integrity via Akt/GSK3beta signaling Neurochemistry International 59 2011 749 758
    • (2011) Neurochemistry International , vol.59 , pp. 749-758
    • Zhou, C.1    Tu, J.2    Zhang, Q.3    Lu, D.4    Zhu, Y.5    Zhang, W.6    Yang, F.7    Brann, D.W.8    Wang, R.9
  • 39
    • 54249167953 scopus 로고    scopus 로고
    • Neuroprotective effects of berberine on stroke models in vitro and in vivo
    • X.Q. Zhou, X.N. Zeng, H. Kong, and X.L. Sun Neuroprotective effects of berberine on stroke models in vitro and in vivo Neuroscience Letters 447 2008 31 36
    • (2008) Neuroscience Letters , vol.447 , pp. 31-36
    • Zhou, X.Q.1    Zeng, X.N.2    Kong, H.3    Sun, X.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.