Efficient delivery of immunostimulatory DNA to mouse and human immune cells through the construction of polypod-like structured DNA

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 10, Issue 4, 2014, Pages 765-774

  Uno, Shota ^a   Nishikawa, Makiya ^a,b   Mohri, Kohta ^a   Umeki, Yuka ^a   Matsuzaki, Noriyuki ^a   Takahashi, Yuki ^a,b   Fujita, Haruyuki ^a   Kadowaki, Norimitsu ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

CpG DNA; Dendritic cell; Peripheral blood mononuclear cell; Toll like receptor 9

Indexed keywords

CYTOLOGY; INTERFERONS; MACROPHAGES; MAMMALS; VIRUSES;

DENDRITIC CELLS; HUMAN PERIPHERAL BLOOD; IMMUNOSTIMULATORY ACTIVITIES; INTRADERMAL INJECTION; OLIGODEOXYNUCLEOTIDES; PERIPHERAL BLOOD MONONUCLEAR CELLS; SINGLE-STRANDED DNA; TOLL-LIKE RECEPTOR 9;

DNA;

ALPHA INTERFERON; CYTOCHALASIN B; DANSYLCADAVERINE; DNA; IMMUNOSTIMULATING AGENT; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 6; SINGLE STRANDED DNA; TOLL LIKE RECEPTOR 9; IMMUNOLOGICAL ADJUVANT;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL TYPE; COMPARATIVE STUDY; CPG ISLAND; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; DNA STRUCTURE; GENE DELIVERY SYSTEM; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOSTIMULATION; IMMUNOTHERAPY; INTERNALIZATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; REPLICON; ANIMAL; BONE MARROW CELL; CELL LINE; CHEMISTRY; CYTOLOGY; IMMUNOLOGY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BONE MARROW CELLS; CELL LINE; DENDRITIC CELLS; DNA; HUMANS; INTERFERON-ALPHA; MACROPHAGES; MALE; MICE;

EID: 84900319032     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.11.017     Document Type: Article

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