Design and development of nanosized DNA assemblies in polypod-like structures as efficient vehicles for immunostimulatory cpg motifs to immune cells

ACS Nano

Volumn 6, Issue 7, 2012, Pages 5931-5940

  Mohri, Kohta ^a   Nishikawa, Makiya ^a   Takahashi, Natsuki ^a   Shiomi, Tomoki ^a   Matsuoka, Nao ^a   Ogawa, Kohei ^a   Endo, Masayuki ^b   Hidaka, Kumi ^a   Sugiyama, Hiroshi ^a,b   Takahashi, Yuki ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

CpG motif; macrophage; nanoassembly; phosphodiester DNA; polypod like structure

Indexed keywords

BRANCHED DNA; CHLORIDE CONCENTRATIONS; CPG MOTIF; DESIGN AND DEVELOPMENT; DINUCLEOTIDES; DNA ASSEMBLIES; HIGH-SPEED; IMMUNE CELLS; IMMUNOLOGICAL PROPERTIES; INTERLEUKIN-6; NANO-ASSEMBLIES; NANO-SIZED; OLIGODEOXYNUCLEOTIDES; PHOSPHODIESTERS; POD NUMBER; SPECTRAL DATA; TUMOR NECROSIS FACTORS;

ATOMIC FORCE MICROSCOPY; BIODEGRADATION; DENDRIMERS; ESTERS; MACROPHAGES; PHYSIOLOGY; SODIUM CHLORIDE;

DNA;

DNA; NANOMATERIAL;

ANIMAL; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CPG ISLAND; DRUG EFFECT; IMMUNIZATION; IMMUNOLOGY; MACROPHAGE; METHODOLOGY; MOUSE; NANOTECHNOLOGY; PARTICLE SIZE; ULTRASTRUCTURE;

ANIMALS; CELL LINE; CPG ISLANDS; DNA; IMMUNIZATION; MACROPHAGES; MICE; MICROSCOPY, ATOMIC FORCE; MODELS, MOLECULAR; NANOSTRUCTURES; NANOTECHNOLOGY; NUCLEIC ACID CONFORMATION; PARTICLE SIZE;

EID: 84864187015     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn300727j     Document Type: Article

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