메뉴 건너뛰기




Volumn 29, Issue 3, 2010, Pages 1-7

Cerebral cavernous malformations as a disease of vascular permeability: From bench to bedside with caution

Author keywords

Angiogenesis; CCM1; CCM2; CCM3; Cerebral cavernous malformation; Endothelial cell junction; Genetics

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CARRIER PROTEIN; CCM2 PROTEIN, HUMAN; KRIT1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; ONCOPROTEIN; PDCD10 PROTEIN, HUMAN;

EID: 77956215617     PISSN: None     EISSN: 10920684     Source Type: Journal    
DOI: 10.3171/2010.5.FOCUS10121     Document Type: Article
Times cited : (54)

References (82)
  • 1
    • 34548310428 scopus 로고    scopus 로고
    • Sunitinib malate for the treatment of metastatic renal cell carcinoma and gastrointestinal stromal tumors
    • Adams VR, Leggas M. Sunitinib malate for the treatment of metastatic renal cell carcinoma and gastrointestinal stromal tumors. Clin Ther 29:1338-1353, 2007
    • (2007) Clin Ther , vol.29 , pp. 1338-1353
    • Adams, V.R.1    Leggas, M.2
  • 3
    • 60549102885 scopus 로고    scopus 로고
    • Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis
    • Akers AL, Johnson E, Steinberg GK, Zabramski JM, Marchuk DA. Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis. Hum Mol Genet 18:919-930, 2009
    • (2009) Hum Mol Genet , vol.18 , pp. 919-930
    • Akers, A.L.1    Johnson, E.2    Steinberg, G.K.3    Zabramski, J.M.4    Marchuk, D.A.5
  • 4
    • 0038222578 scopus 로고    scopus 로고
    • Prospective, population-based detection of intracranial vascular malformations in adults: the Scottish Intracranial Vascular Malformation Study (SIVMS)
    • Al-Shahi R, Bhattacharya JJ, Currie DG, Papanastassiou V, Ritchie V, Roberts RC, et al. Prospective, population-based detection of intracranial vascular malformations in adults: the Scottish Intracranial Vascular Malformation Study (SIVMS). Stroke 34:1163-1169, 2003
    • (2003) Stroke , vol.34 , pp. 1163-1169
    • Al-Shahi, R.1    Bhattacharya, J.J.2    Currie, D.G.3    Papanastassiou, V.4    Ritchie, V.5    Roberts, R.C.6
  • 5
    • 15944412799 scopus 로고    scopus 로고
    • Unfolding knowledge on cerebral cavernous malformations
    • Awad IA. Unfolding knowledge on cerebral cavernous malformations. Surg Neurol 63:317-318, 2005
    • (2005) Surg Neurol , vol.63 , pp. 317-318
    • Awad, I.A.1
  • 6
  • 7
    • 19944394831 scopus 로고    scopus 로고
    • Mutations within the programmed cell death 10 gene cause cerebral cavernous malformations
    • Bergametti F, Denier C, Labauge P, Arnoult M, Boetto S, Clanet M, et al. Mutations within the programmed cell death 10 gene cause cerebral cavernous malformations. Am J Hum Genet 76:42-51, 2005
    • (2005) Am J Hum Genet , vol.76 , pp. 42-51
    • Bergametti, F.1    Denier, C.2    Labauge, P.3    Arnoult, M.4    Boetto, S.5    Clanet, M.6
  • 9
    • 59649086507 scopus 로고    scopus 로고
    • Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations
    • Boulday G, Blécon A, Petit N, Chareyre F, Garcia LA, NiwaKawakita M, et al. Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations. Dis Model Mech 2:168-177, 2009
    • (2009) Dis Model Mech , vol.2 , pp. 168-177
    • Boulday, G.1    Blécon, A.2    Petit, N.3    Chareyre, F.4    Garcia, L.A.5    NiwaKawakita, M.6
  • 10
    • 18744385547 scopus 로고    scopus 로고
    • De novo development of a lesion with the appearance of a cavernous malformation adjacent to an existing developmental venous anomaly
    • Campeau NG, Lane JI. De novo development of a lesion with the appearance of a cavernous malformation adjacent to an existing developmental venous anomaly. AJNR Am J Neuroradiol 26:156-159, 2005
    • (2005) AJNR Am J Neuroradiol , vol.26 , pp. 156-159
    • Campeau, N.G.1    Lane, J.I.2
  • 11
    • 18744374458 scopus 로고    scopus 로고
    • Spectrum and expression analysis of KRIT1 mutations in 121 consecutive and unrelated patients with cerebral cavernous malformations
    • Cavé-Riant F, Denier C, Labauge P, Cécillon M, Maciazek J, Joutel A, et al. Spectrum and expression analysis of KRIT1 mutations in 121 consecutive and unrelated patients with cerebral cavernous malformations. Eur J Hum Genet 10:733- 740, 2002
    • (2002) Eur J Hum Genet , vol.10 , pp. 733-740
    • Cavé-Riant, F.1    Denier, C.2    Labauge, P.3    Cécillon, M.4    Maciazek, J.5    Joutel, A.6
  • 12
    • 65249182536 scopus 로고    scopus 로고
    • Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation
    • Chen L, Tanriover G, Yano H, Friedlander R, Louvi A, Gunel M. Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation Stroke 40:1474-1481, 2009
    • (2009) Stroke , vol.40 , pp. 1474-1481
    • Chen, L.1    Tanriover, G.2    Yano, H.3    Friedlander, R.4    Louvi, A.5    Gunel, M.6
  • 13
    • 0014911956 scopus 로고
    • Familial occurrence of cavernous angiomata of the brain
    • Clark JV. Familial occurrence of cavernous angiomata of the brain. J Neurol Neurosurg Psychiatry 33:871-876, 1970
    • (1970) J Neurol Neurosurg Psychiatry , vol.33 , pp. 871-876
    • Clark, J.V.1
  • 14
    • 0034925464 scopus 로고    scopus 로고
    • Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations
    • Clatterbuck RE, Eberhart CG, Crain BJ, Rigamonti D. Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations. J Neurol Neurosurg Psychiatry 71:188-192, 2001
    • (2001) J Neurol Neurosurg Psychiatry , vol.71 , pp. 188-192
    • Clatterbuck, R.E.1    Eberhart, C.G.2    Crain, B.J.3    Rigamonti, D.4
  • 15
    • 0029155898 scopus 로고
    • Seizure outcome after lesionectomy for cavernous malformations
    • Cohen DS, Zubay GP, Goodman RR. Seizure outcome after lesionectomy for cavernous malformations. J Neurosurg 83: 237-242, 1995
    • (1995) J Neurosurg , vol.83 , pp. 237-242
    • Cohen, D.S.1    Zubay, G.P.2    Goodman, R.R.3
  • 16
    • 33746488397 scopus 로고    scopus 로고
    • Sorting nexin 17, a non-self-assembling and a PtdIns(3)P high class affinity protein, interacts with the cerebral cavernous malformation related protein KRIT
    • Czubayko M, Knauth P, Schlüter T, Florian V, Bohnensack R. Sorting nexin 17, a non-self-assembling and a PtdIns(3)P high class affinity protein, interacts with the cerebral cavernous malformation related protein KRITBiochem Biophys Res Commun 345:1264-1272, 2006
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 1264-1272
    • Czubayko, M.1    Knauth, P.2    Schlüter, T.3    Florian, V.4    Bohnensack, R.5
  • 17
    • 33747176779 scopus 로고    scopus 로고
    • Molecular genetics of familial cerebral cavernous malformations
    • Dashti SR, Hoffer A, Hu YC, Selman WR. Molecular genetics of familial cerebral cavernous malformations. Neurosurg Focus 21(1):e2, 2006
    • (2006) Neurosurg Focus , vol.21 , Issue.1
    • Dashti, S.R.1    Hoffer, A.2    Hu, Y.C.3    Selman, W.R.4
  • 18
    • 0036768349 scopus 로고    scopus 로고
    • Krit1/cerebral cavernous malformation 1 mRNA is preferentially expressed in neurons and epithelial cells in embryo and adult
    • Denier C, Gasc JM, Chapon F, Domenga V, Lescoat C, Joutel A, et al. Krit1/cerebral cavernous malformation 1 mRNA is preferentially expressed in neurons and epithelial cells in embryo and adult. Mech Dev 117:363-367, 2002
    • (2002) Mech Dev , vol.117 , pp. 363-367
    • Denier, C.1    Gasc, J.M.2    Chapon, F.3    Domenga, V.4    Lescoat, C.5    Joutel, A.6
  • 24
    • 33645687956 scopus 로고    scopus 로고
    • Cerebral cavernomas and seizures: a retrospective study on 163 patients who underwent pure lesionectomy
    • Ferroli P, Casazza M, Marras C, Mendola C, Franzini A, Broggi G. Cerebral cavernomas and seizures: a retrospective study on 163 patients who underwent pure lesionectomy. Neurol Sci 26:390-394, 2006
    • (2006) Neurol Sci , vol.26 , pp. 390-394
    • Ferroli, P.1    Casazza, M.2    Marras, C.3    Mendola, C.4    Franzini, A.5    Broggi, G.6
  • 25
    • 77951194603 scopus 로고    scopus 로고
    • CCM3/PDCD10 stabilizes GCKIII proteins to promote Gol-gi assembly and cell orientation
    • Fidalgo M, Fraile M, Pires A, Force T, Pombo C, Zalvide J. CCM3/PDCD10 stabilizes GCKIII proteins to promote Gol-gi assembly and cell orientation. J Cell Sci 123:1274-1284, 2010
    • (2010) J Cell Sci , vol.123 , pp. 1274-1284
    • Fidalgo, M.1    Fraile, M.2    Pires, A.3    Force, T.4    Pombo, C.5    Zalvide, J.6
  • 26
    • 57749178396 scopus 로고    scopus 로고
    • Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis
    • Francalanci F, Avolio M, De Luca E, Longo D, Menchise V, Guazzi P, et al. Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis. Exp Cell Res 315:285-303, 2009
    • (2009) Exp Cell Res , vol.315 , pp. 285-303
    • Francalanci, F.1    Avolio, M.2    De Luca, E.3    Longo, D.4    Menchise, V.5    Guazzi, P.6
  • 28
    • 67651153055 scopus 로고    scopus 로고
    • Cerebral cavernous malformations: somatic mutations in vascular endothelial cells
    • Gault J, Awad IA, Recksiek P, Shenkar R, Breeze R, Handler M, et al. Cerebral cavernous malformations: somatic mutations in vascular endothelial cells. Neurosurgery 65:138-145, 2009
    • (2009) Neurosurgery , vol.65 , pp. 138-145
    • Gault, J.1    Awad, I.A.2    Recksiek, P.3    Shenkar, R.4    Breeze, R.5    Handler, M.6
  • 29
    • 35548936992 scopus 로고    scopus 로고
    • KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions
    • Glading A, Han J, Stockton RA, Ginsberg MH. KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions. J Cell Biol 179:247-254, 2007
    • (2007) J Cell Biol , vol.179 , pp. 247-254
    • Glading, A.1    Han, J.2    Stockton, R.A.3    Ginsberg, M.H.4
  • 32
    • 12144290066 scopus 로고    scopus 로고
    • KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortex
    • Guzeloglu-Kayisli O, Amankulor NM, Voorhees J, Luleci G, Lifton RP, Gunel M. KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortex. Neurosurgery 54:943-949, 2004
    • (2004) Neurosurgery , vol.54 , pp. 943-949
    • Guzeloglu-Kayisli, O.1    Amankulor, N.M.2    Voorhees, J.3    Luleci, G.4    Lifton, R.P.5    Gunel, M.6
  • 35
    • 57649132133 scopus 로고    scopus 로고
    • Novel KRIT1 mutation and no molecular evidence of anticipation in a family with cerebral and spinal cavernous malformations
    • Kuhn J, Brümmendorf TH, Brassat U, Lehnhardt FG, Chung BD, Harnier S, et al. Novel KRIT1 mutation and no molecular evidence of anticipation in a family with cerebral and spinal cavernous malformations. Eur Neurol 61:154-158, 2009
    • (2009) Eur Neurol , vol.61 , pp. 154-158
    • Kuhn, J.1    Brümmendorf, T.H.2    Brassat, U.3    Lehnhardt, F.G.4    Chung, B.D.5    Harnier, S.6
  • 36
    • 34249330323 scopus 로고    scopus 로고
    • Familial forms of central nervous system cavernomas: from recognition to gene therapy
    • (Fr)
    • Labauge P. [Familial forms of central nervous system cavernomas: from recognition to gene therapy.] Neurochirurgie 53:152-155, 2007 (Fr)
    • (2007) Neurochirurgie , vol.53 , pp. 152-155
    • Labauge, P.1
  • 38
    • 0031965109 scopus 로고    scopus 로고
    • Formation of intracerebral cavernous malformations after radiation treatment for central nervous system neoplasia in children
    • Larson JJ, Ball WS, Bove KE, Crone KR, Tew JM Jr. Formation of intracerebral cavernous malformations after radiation treatment for central nervous system neoplasia in children. J Neurosurg 88:51-56, 1998
    • (1998) J Neurosurg , vol.88 , pp. 51-56
    • Larson, J.J.1    Ball, W.S.2    Bove, K.E.3    Crone, K.R.4    Tew J.M., Jr.5
  • 40
    • 0024829882 scopus 로고
    • Cerebral cavernous malformations
    • (Letter)
    • Lee KS, Spetzler RF. Cerebral cavernous malformations. Arch Neurol 46:1273, 1989 (Letter)
    • (1989) Arch Neurol , vol.46 , pp. 1273
    • Lee, K.S.1    Spetzler, R.F.2
  • 41
    • 9144261692 scopus 로고    scopus 로고
    • Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations
    • Liquori CL, Berg MJ, Siegel AM, Huang E, Zawistowski JS, Stoffer T, et al. Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations. Am J Hum Genet 73: 1459-1464, 2003
    • (2003) Am J Hum Genet , vol.73 , pp. 1459-1464
    • Liquori, C.L.1    Berg, M.J.2    Siegel, A.M.3    Huang, E.4    Zawistowski, J.S.5    Stoffer, T.6
  • 43
    • 34548083040 scopus 로고    scopus 로고
    • Low frequency of PDCD10 mutations in a panel of CCM3 probands: potential for a fourth CCM locus
    • Liquori CL, Berg MJ, Squitieri F, Ottenbacher M, Sorlie M, Leedom TP, et al. Low frequency of PDCD10 mutations in a panel of CCM3 probands: potential for a fourth CCM locus. Hum Mutat 27:118, 2006
    • (2006) Hum Mutat , vol.27 , pp. 118
    • Liquori, C.L.1    Berg, M.J.2    Squitieri, F.3    Ottenbacher, M.4    Sorlie, M.5    Leedom, T.P.6
  • 44
    • 0035072776 scopus 로고    scopus 로고
    • Germline mutations in the CCM1 gene, encoding Krit1, cause cerebral cavernous malformations
    • Lucas M, Costa AF, Montori M, Solano F, Zayas MD, Izquierdo G. Germline mutations in the CCM1 gene, encoding Krit1, cause cerebral cavernous malformations. Ann Neurol 49: 529-532, 2001
    • (2001) Ann Neurol , vol.49 , pp. 529-532
    • Lucas, M.1    Costa, A.F.2    Montori, M.3    Solano, F.4    Zayas, M.D.5    Izquierdo, G.6
  • 45
    • 33747182226 scopus 로고    scopus 로고
    • Clinical progression and familial occurrence of cerebral cavernous angiomas: the role of angiogenic and growth factors
    • Maiuri F, Cappabianca P, Gangemi M, De Caro MdelB, Esposito F, Pettinato G, et al. Clinical progression and familial occurrence of cerebral cavernous angiomas: the role of angiogenic and growth factors. Neurosurg Focus 21(1):e3, 2006
    • (2006) Neurosurg Focus , vol.21 , Issue.1
    • Maiuri, F.1    Cappabianca, P.2    Gangemi, M.3    De Caro Mdel, B.4    Esposito, F.5    Pettinato, G.6
  • 47
    • 34547642109 scopus 로고    scopus 로고
    • Maraviroc, a chemokine CCR5 receptor antagonist for the treatment of HIV infection and AIDS
    • Meanwell NA, Kadow JF. Maraviroc, a chemokine CCR5 receptor antagonist for the treatment of HIV infection and AIDS. Curr Opin Investig Drugs 8:669-681, 2007
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 669-681
    • Meanwell, N.A.1    Kadow, J.F.2
  • 48
    • 76449094050 scopus 로고    scopus 로고
    • Understanding the molecular-based mechanism of action of the tyrosine kinase inhibitor: sunitinib
    • Mena AC, Pulido EG, Guillén-Ponce C. Understanding the molecular-based mechanism of action of the tyrosine kinase inhibitor: sunitinib. Anticancer Drugs 21 (Suppl 1):S3-S11, 2010
    • (2010) Anticancer Drugs , vol.21 , Issue.SUPPL 1
    • Mena, A.C.1    Pulido, E.G.2    Guillén-Ponce, C.3
  • 49
    • 33847057304 scopus 로고    scopus 로고
    • Imatinib: a review of its use in chronic myeloid leukaemia
    • Moen MD, McKeage K, Plosker GL, Siddiqui MA. Imatinib: a review of its use in chronic myeloid leukaemia. Drugs 67: 299-320, 2007
    • (2007) Drugs , vol.67 , pp. 299-320
    • Moen, M.D.1    McKeage, K.2    Plosker, G.L.3    Siddiqui, M.A.4
  • 51
    • 33747156929 scopus 로고    scopus 로고
    • Review of the literature on de novo formation of cavernous malformations of the central nervous system after radiation therapy
    • Nimjee SM, Powers CJ, Bulsara KR. Review of the literature on de novo formation of cavernous malformations of the central nervous system after radiation therapy. Neurosurg Focus 21(1):e4, 2006
    • (2006) Neurosurg Focus , vol.21 , Issue.1
    • Nimjee, S.M.1    Powers, C.J.2    Bulsara, K.R.3
  • 52
    • 27744602620 scopus 로고    scopus 로고
    • Management of patients with cavernous angiomas presenting epileptic seizures
    • Noto S, Fujii M, Akimura T, Imoto H, Nomura S, Kajiwara K, et al. Management of patients with cavernous angiomas presenting epileptic seizures. Surg Neurol 64:495-499, 2005
    • (2005) Surg Neurol , vol.64 , pp. 495-499
    • Noto, S.1    Fujii, M.2    Akimura, T.3    Imoto, H.4    Nomura, S.5    Kajiwara, K.6
  • 53
    • 0032816127 scopus 로고    scopus 로고
    • Microsurgical treatment of supratentorial cavernous malformations
    • Ojemann RG, Ogilvy CS. Microsurgical treatment of supratentorial cavernous malformations. Neurosurg Clin N Am 10:433-440, 1999
    • (1999) Neurosurg Clin N Am , vol.10 , pp. 433-440
    • Ojemann, R.G.1    Ogilvy, C.S.2
  • 54
    • 60549083320 scopus 로고    scopus 로고
    • A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells
    • Pagenstecher A, Stahl S, Sure U, Felbor U. A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells. Hum Mol Genet 18:911-918, 2009
    • (2009) Hum Mol Genet , vol.18 , pp. 911-918
    • Pagenstecher, A.1    Stahl, S.2    Sure, U.3    Felbor, U.4
  • 55
    • 59649101392 scopus 로고    scopus 로고
    • Torturing a blood vessel
    • Patterson C. Torturing a blood vessel. Nat Med 15:137-138, 2009
    • (2009) Nat Med , vol.15 , pp. 137-138
    • Patterson, C.1
  • 56
    • 33747172797 scopus 로고    scopus 로고
    • The association of venous developmental anomalies and cavernous malformations: pathophysiological, diagnostic, and surgical considerations
    • Perrini P, Lanzino G. The association of venous developmental anomalies and cavernous malformations: pathophysiological, diagnostic, and surgical considerations. Neurosurg Focus 21(1):e5, 2006
    • (2006) Neurosurg Focus , vol.21 , Issue.1
    • Perrini, P.1    Lanzino, G.2
  • 57
    • 76749130195 scopus 로고    scopus 로고
    • Familial versus sporadic cavernous malformations: differences in developmental venous anomaly association and lesion phenotype
    • Petersen TA, Morrison LA, Schrader RM, Hart BL. Familial versus sporadic cavernous malformations: differences in developmental venous anomaly association and lesion phenotype. AJNR Am J Neuroradiol 31:377-382, 2010
    • (2010) AJNR Am J Neuroradiol , vol.31 , pp. 377-382
    • Petersen, T.A.1    Morrison, L.A.2    Schrader, R.M.3    Hart, B.L.4
  • 58
    • 33744900611 scopus 로고    scopus 로고
    • Patterns of expression of the three cerebral cavernous malformation (CCM) genes during embryonic and postnatal brain development
    • Petit N, Blécon A, Denier C, Tournier-Lasserve E. Patterns of expression of the three cerebral cavernous malformation (CCM) genes during embryonic and postnatal brain development. Gene Expr Patterns 6:495-503, 2006
    • (2006) Gene Expr Patterns , vol.6 , pp. 495-503
    • Petit, N.1    Blécon, A.2    Denier, C.3    Tournier-Lasserve, E.4
  • 60
    • 7244251522 scopus 로고    scopus 로고
    • Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations
    • Plummer NW, Gallione CJ, Srinivasan S, Zawistowski JS, Louis DN, Marchuk DA. Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations. Am J Pathol 165:1509-1518, 2004
    • (2004) Am J Pathol , vol.165 , pp. 1509-1518
    • Plummer, N.W.1    Gallione, C.J.2    Srinivasan, S.3    Zawistowski, J.S.4    Louis, D.N.5    Marchuk, D.A.6
  • 61
    • 33749263696 scopus 로고    scopus 로고
    • Cerebral cavernous malformation: new molecular and clinical insights
    • Revencu N, Vikkula M. Cerebral cavernous malformation: new molecular and clinical insights. J Med Genet 43:716- 721, 2006
    • (2006) J Med Genet , vol.43 , pp. 716-721
    • Revencu, N.1    Vikkula, M.2
  • 63
    • 0003720752 scopus 로고
    • Russell D.S. Rubinstein L.J. (eds). ed 5. Baltimore: Williams & Wilkins
    • Russell DS, Rubinstein LJ (eds). Pathology of Tumours of the Nervous System, ed 5. Baltimore: Williams & Wilkins, 1989
    • (1989) Pathology of Tumours of the Nervous System
  • 66
    • 0030761145 scopus 로고    scopus 로고
    • Association of Krev-1/rap1a with Krit1, a novel ankyrin repeatcontaining protein encoded by a gene mapping to 7q21-22
    • Serebriiskii I, Estojak J, Sonoda G, Testa JR, Golemis EA. Association of Krev-1/rap1a with Krit1, a novel ankyrin repeatcontaining protein encoded by a gene mapping to 7q21-22 Oncogene 15:1043-1049, 1997
    • (1997) Oncogene , vol.15 , pp. 1043-1049
    • Serebriiskii, I.1    Estojak, J.2    Sonoda, G.3    Testa, J.R.4    Golemis, E.A.5
  • 67
    • 56749153931 scopus 로고    scopus 로고
    • Advanced magnetic resonance imaging of cerebral cavernous malformations: part II. Imaging of lesions in murine models
    • Shenkar R, Venkatasubramanian PN, Wyrwicz AM, Zhao JC, Shi C, Akers A, et al. Advanced magnetic resonance imaging of cerebral cavernous malformations: part II. Imaging of lesions in murine models. Neurosurgery 63:790-798, 2008
    • (2008) Neurosurgery , vol.63 , pp. 790-798
    • Shenkar, R.1    Venkatasubramanian, P.N.2    Wyrwicz, A.M.3    Zhao, J.C.4    Shi, C.5    Akers, A.6
  • 68
    • 37149043250 scopus 로고    scopus 로고
    • Oligoclonal immune response in cerebral cavernous malformations Laboratory investigation
    • Shi C, Shenkar R, Batjer HH, Check IJ, Awad IA. Oligoclonal immune response in cerebral cavernous malformations. Laboratory investigation. J Neurosurg 107:1023-1026, 2007
    • (2007) J Neurosurg , vol.107 , pp. 1023-1026
    • Shi, C.1    Shenkar, R.2    Batjer, H.H.3    Check, I.J.4    Awad, I.A.5
  • 69
    • 65549085584 scopus 로고    scopus 로고
    • Immune response in human cerebral cavernous malformations
    • Shi C, Shenkar R, Du H, Duckworth E, Raja H, Batjer HH, et al. Immune response in human cerebral cavernous malformations. Stroke 40:1659-1665, 2009
    • (2009) Stroke , vol.40 , pp. 1659-1665
    • Shi, C.1    Shenkar, R.2    Du, H.3    Duckworth, E.4    Raja, H.5    Batjer, H.H.6
  • 70
    • 77951044950 scopus 로고    scopus 로고
    • Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity
    • Stockton RA, Shenkar R, Awad IA, Ginsberg MH. Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity. J Exp Med 207:881-896, 2010
    • (2010) J Exp Med , vol.207 , pp. 881-896
    • Stockton, R.A.1    Shenkar, R.2    Awad, I.A.3    Ginsberg, M.H.4
  • 72
    • 77956221431 scopus 로고    scopus 로고
    • CCM2 and CCM3 proteins contribute to vasculogenesis and angiogenesis in human placenta
    • Tanriover G, Seval Y, Sati L, Gunel M, Demir N. CCM2 and CCM3 proteins contribute to vasculogenesis and angiogenesis in human placenta. Histol Histopathol 24:1287-1294, 2009
    • (2009) Histol Histopathol , vol.24 , pp. 1287-1294
    • Tanriover, G.1    Seval, Y.2    Sati, L.3    Gunel, M.4    Demir, N.5
  • 73
    • 0034692421 scopus 로고    scopus 로고
    • Molecular adaptors for vascular-targeted adenoviral gene delivery
    • Trepel M, Grifman M, Weitzman MD, Pasqualini R. Molecular adaptors for vascular-targeted adenoviral gene delivery. Hum Gene Ther 11:1971-1981, 2000
    • (2000) Hum Gene Ther , vol.11 , pp. 1971-1981
    • Trepel, M.1    Grifman, M.2    Weitzman, M.D.3    Pasqualini, R.4
  • 74
    • 32044438698 scopus 로고    scopus 로고
    • Ultrastructural characteristics of hemorrhagic, nonhemorrhagic, and recurrent cavernous malformations
    • Tu J, Stoodley MA, Morgan MK, Storer KP. Ultrastructural characteristics of hemorrhagic, nonhemorrhagic, and recurrent cavernous malformations. J Neurosurg 103:903-909, 2005
    • (2005) J Neurosurg , vol.103 , pp. 903-909
    • Tu, J.1    Stoodley, M.A.2    Morgan, M.K.3    Storer, K.P.4
  • 75
    • 34948833449 scopus 로고    scopus 로고
    • CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations
    • Voss K, Stahl S, Schleider E, Ullrich S, Nickel J, Mueller TD, et al. CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations. Neurogenetics 8:249-256, 2007
    • (2007) Neurogenetics , vol.8 , pp. 249-256
    • Voss, K.1    Stahl, S.2    Schleider, E.3    Ullrich, S.4    Nickel, J.5    Mueller, T.D.6
  • 76
    • 59649084619 scopus 로고    scopus 로고
    • The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases
    • (Erratum in Nat Med 15:462, 2009)
    • Whitehead KJ, Chan AC, Navankasattusas S, Koh W, London NR, Ling J, et al. The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases. Nat Med 15:177-184, 2009 (Erratum in Nat Med 15:462, 2009)
    • (2009) Nat Med , vol.15 , pp. 177-184
    • Whitehead, K.J.1    Chan, A.C.2    Navankasattusas, S.3    Koh, W.4    London, N.R.5    Ling, J.6
  • 77
    • 1842559498 scopus 로고    scopus 로고
    • Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations
    • Whitehead KJ, Plummer NW, Adams JA, Marchuk DA, Li DY. Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations. Development 131:1437-1448, 2004
    • (2004) Development , vol.131 , pp. 1437-1448
    • Whitehead, K.J.1    Plummer, N.W.2    Adams, J.A.3    Marchuk, D.A.4    Li, D.Y.5
  • 78
    • 0034517320 scopus 로고    scopus 로고
    • Ultrastructural pathological features of cerebrovascular malformations: a preliminary report
    • Wong JH, Awad IA, Kim JH. Ultrastructural pathological features of cerebrovascular malformations: a preliminary report. Neurosurgery 46:1454-1459, 2000
    • (2000) Neurosurgery , vol.46 , pp. 1454-1459
    • Wong, J.H.1    Awad, I.A.2    Kim, J.H.3
  • 79
    • 24144454827 scopus 로고    scopus 로고
    • CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis
    • Zawistowski JS, Stalheim L, Uhlik MT, Abell AN, Ancrile BB, Johnson GL, et al. CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis. Hum Mol Genet 14:2521-2531, 2005
    • (2005) Hum Mol Genet , vol.14 , pp. 2521-2531
    • Zawistowski, J.S.1    Stalheim, L.2    Uhlik, M.T.3    Abell, A.N.4    Ancrile, B.B.5    Johnson, G.L.6
  • 80
    • 0029818764 scopus 로고    scopus 로고
    • Seizure control following surgery in supratentorial cavernous malformations: a retrospective study in 77 patients
    • (Wien)
    • Zevgaridis D, van Velthoven V, Ebeling U, Reulen HJ. Seizure control following surgery in supratentorial cavernous malformations: a retrospective study in 77 patients. Acta Neurochir (Wien) 138:672-677, 1996
    • (1996) Acta Neurochir , vol.138 , pp. 672-677
    • Zevgaridis, D.1    van Velthoven, V.2    Ebeling, U.3    Reulen, H.J.4
  • 82
    • 33847001613 scopus 로고    scopus 로고
    • Interaction between krit1 and malcavernin: implications for the pathogenesis of cerebral cavernous malformations
    • Zhang J, Rigamonti D, Dietz HC, Clatterbuck RE. Interaction between krit1 and malcavernin: implications for the pathogenesis of cerebral cavernous malformations. Neurosurgery 60:353-359, 2007
    • (2007) Neurosurgery , vol.60 , pp. 353-359
    • Zhang, J.1    Rigamonti, D.2    Dietz, H.C.3    Clatterbuck, R.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.