Crystal structure of human programmed cell death 10 complexed with inositol-(1,3,4,5)-tetrakisphosphate: A novel adaptor protein involved in human cerebral cavernous malformation

Biochemical and Biophysical Research Communications

Volumn 399, Issue 4, 2010, Pages 587-592

  Ding, Jingjin ^a   Wang, Xiaoyan ^a   Li, De Feng ^a   Hu, Yonglin ^a   Zhang, Ying ^a   Wang, Da Cheng ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

Adaptor protein; Binding partner recruitment; Conformational variability; Phosphatidylinositide binding; Programmed cell death 10; Unique dimeric assembly

Indexed keywords

ADAPTOR PROTEIN; DIMER; FOCAL ADHESION KINASE; INOSITOL 1,3,4,5 TETRAKISPHOSPHATE; MONOMER; PAXILLIN; PHOSPHATIDYLINOSITIDE; PROGRAMMED CELL DEATH 10; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; INOSITOL PHOSPHATE; INOSITOL-1,2,4,5-TETRAKISPHOSPHATE; MEMBRANE PROTEIN; ONCOPROTEIN; PDCD10 PROTEIN, HUMAN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN MALFORMATION; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CEREBRAL CAVERNOUS MALFORMATION; CRYSTAL STRUCTURE; FOCAL ADHESION; GERMINAL CENTER; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; BINDING SITE; CENTRAL NERVOUS SYSTEM MALFORMATION; CHEMISTRY; HUMAN; METABOLISM; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

APOPTOSIS REGULATORY PROTEINS; BINDING SITES; CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS; CRYSTALLOGRAPHY, X-RAY; HUMANS; INOSITOL PHOSPHATES; MEMBRANE PROTEINS; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS;

EID: 77956262153     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.07.119     Document Type: Article

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