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Volumn 52, Issue 2, 2014, Pages 94-100

The effect of vitamin A supplementation on disease progression, Cytokine levels and gene expression in multiple sclerotic patients: Study protocol for a randomized controlled trial

Author keywords

Cytokine; Gene expression; Magnetic resonance imaging; Multiple sclerosis; Vitamin A

Indexed keywords

BETA ACTIN; BETA1A INTERFERON; CHOLESTEROL; CINOVEX; COMPLEMENTARY DNA; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 4; MESSENGER RNA; PLACEBO; PREALBUMIN; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR BETA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; RETINOL; RETINOL BINDING PROTEIN; RETINOL PALMITATE; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TRANSFORMING GROWTH FACTOR BETA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84900028884     PISSN: 00446025     EISSN: 17359694     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (29)
  • 1
    • 84855598095 scopus 로고    scopus 로고
    • Current Status of the Immunomodulation and Immunomediated Therapeutic Strategies for Multiple Sclerosis
    • Chen SJ, Wang YL, Fan HC, et al. Current Status of the Immunomodulation and Immunomediated Therapeutic Strategies for Multiple Sclerosis. Clin Dev Immunol 2012;2012:970789.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 970789
    • Chen, S.J.1    Wang, Y.L.2    Fan, H.C.3
  • 2
    • 79952828577 scopus 로고    scopus 로고
    • Advanced MRI in Multiple Sclerosis. Current Status and Future Challenges
    • Fox RJ, Beall E, Bhattacharyya P, et al. Advanced MRI in Multiple Sclerosis. Current Status and Future Challenges. Neurol Clin 2011;29(2):357-80.
    • (2011) Neurol Clin , vol.29 , Issue.2 , pp. 357-380
    • Fox, R.J.1    Beall, E.2    Bhattacharyya, P.3
  • 3
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis--the plaque and its pathogenesis
    • Frohman EM, Racke MK, Raine CS. Multiple sclerosis--the plaque and its pathogenesis. N Engl J Med 2006;354(9):942-55.
    • (2006) N Engl J Med , vol.354 , Issue.9 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 4
    • 84856228274 scopus 로고    scopus 로고
    • Immunopathogenesis of multiple sclerosis
    • Comabella M, Khoury SJ. Immunopathogenesis of multiple sclerosis. Clin Immunol 2012;142(1):2-8.
    • (2012) Clin Immunol , vol.142 , Issue.1 , pp. 2-8
    • Comabella, M.1    Khoury, S.J.2
  • 5
    • 79958721221 scopus 로고    scopus 로고
    • Th17 Cell, the New Player of Neuroinflammatory Process in Multiple Sclerosis
    • Jadidi-Niaragh F, Mirshafiey A. Th17 Cell, the New Player of Neuroinflammatory Process in Multiple Sclerosis. Scand J Immunol 2011;74(1):1-13.
    • (2011) Scand J Immunol , vol.74 , Issue.1 , pp. 1-13
    • Jadidi-Niaragh, F.1    Mirshafiey, A.2
  • 6
    • 68149179251 scopus 로고    scopus 로고
    • IL-9 as a mediator of Th17-driven inflammatory disease
    • Nowak EC, Weaver CT, Turner H, et al. IL-9 as a mediator of Th17-driven inflammatory disease. J Exp Med 2009;206(8):1653-60.
    • (2009) J Exp Med , vol.206 , Issue.8 , pp. 1653-1660
    • Nowak, E.C.1    Weaver, C.T.2    Turner, H.3
  • 7
    • 65549100690 scopus 로고    scopus 로고
    • Systemic Inflammatory Response eactivates Immune-Mediated Lesions in Rat Brain
    • Serres S, Anthony DC, Jiang Y, et al. Systemic Inflammatory Response eactivates Immune-Mediated Lesions in Rat Brain. J Neurosci 2009;29(15):4820-8.
    • (2009) J Neurosci , vol.29 , Issue.15 , pp. 4820-4828
    • Serres, S.1    Anthony, D.C.2    Jiang, Y.3
  • 8
    • 79952998957 scopus 로고    scopus 로고
    • Immunologic Aspects of Multiple Sclerosis
    • Boppana S, Huang H, Ito K, et al. Immunologic Aspects of Multiple Sclerosis. Mt Sinai J Med 2011;78(2):207-20.
    • (2011) Mt Sinai J Med , vol.78 , Issue.2 , pp. 207-220
    • Boppana, S.1    Huang, H.2    Ito, K.3
  • 9
    • 3142628216 scopus 로고    scopus 로고
    • Immunotherapeutic approaches in multiple sclerosis
    • Adorini L. Immunotherapeutic approaches in multiple sclerosis. J Neurol Sci 2004;223(1):13-24.
    • (2004) J Neurol Sci , vol.223 , Issue.1 , pp. 13-24
    • Adorini, L.1
  • 10
    • 0036186664 scopus 로고    scopus 로고
    • Migration of multiple sclerosis lymphocytes through brain endothelium
    • Prat A, Biernacki K, Lavoie JF, et al. Migration of multiple sclerosis lymphocytes through brain endothelium. Arch Neurol 2002;59(3):391-7.
    • (2002) Arch Neurol , vol.59 , Issue.3 , pp. 391-397
    • Prat, A.1    Biernacki, K.2    Lavoie, J.F.3
  • 11
    • 53149137849 scopus 로고    scopus 로고
    • Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression
    • Xiao S, Jin H, Korn T, et al. Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. J Immunol 2008;181(4):2277-84.
    • (2008) J Immunol , vol.181 , Issue.4 , pp. 2277-2284
    • Xiao, S.1    Jin, H.2    Korn, T.3
  • 12
    • 34447503805 scopus 로고    scopus 로고
    • Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
    • Mucida D, Park Y, Kim G, et al, Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007;317(5835):256-60.
    • (2007) Science , vol.317 , Issue.5835 , pp. 256-260
    • Mucida, D.1    Park, Y.2    Kim, G.3
  • 13
    • 0036348902 scopus 로고    scopus 로고
    • Retinoic acid promotes the development of Th2-like human myelin basic proteinreactive T cells
    • Lovett-Racke AE, Racke MK. Retinoic acid promotes the development of Th2-like human myelin basic proteinreactive T cells. Cell Immunol 2002;215(1):54-60.
    • (2002) Cell Immunol , vol.215 , Issue.1 , pp. 54-60
    • Lovett-Racke, A.E.1    Racke, M.K.2
  • 14
    • 37549038650 scopus 로고    scopus 로고
    • Retinoid metabolism and nuclear receptor responses:New insightsinto coordinated regulation of the PPAR-RXR complex
    • Ziouzenkova O, Plutzky J. Retinoid metabolism and nuclear receptor responses:New insightsinto coordinated regulation of the PPAR-RXR complex. FEBS Lett 2008;582(1):32-8.
    • (2008) FEBS Lett , vol.582 , Issue.1 , pp. 32-38
    • Ziouzenkova, O.1    Plutzky, J.2
  • 15
    • 58149141588 scopus 로고    scopus 로고
    • Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism
    • Parés X, Farrés J, Kedishvili N, et al. Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism. Cell Mol Life Sci 2008;65(24):3936-49.
    • (2008) Cell Mol Life Sci , vol.65 , Issue.24 , pp. 3936-3949
    • Parés, X.1    Farrés, J.2    Kedishvili, N.3
  • 16
    • 7044260964 scopus 로고    scopus 로고
    • Advances in functional and structural MR image analysis and implementation as FSL
    • Smith SM, Jenkinson M, Woolrich MW, et al. Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage 2004;23(1):S208-19
    • (2004) NeuroImage , vol.23 , Issue.1
    • Smith, S.M.1    Jenkinson, M.2    Woolrich, M.W.3
  • 17
    • 0036425968 scopus 로고    scopus 로고
    • Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images
    • Jenkinson M, Bannister P, Brady M, et al. Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images. Neuro Image 2002;17(2):825-41.
    • (2002) Neuro Image , vol.17 , Issue.2 , pp. 825-841
    • Jenkinson, M.1    Bannister, P.2    Brady, M.3
  • 18
    • 0031141035 scopus 로고    scopus 로고
    • SUSAN-A New Approach to Low Level Image Processing
    • Smith SM, Brady JM. SUSAN-A New Approach to Low Level Image Processing. Int J Comput Vis 1997;23(1):45-78.
    • (1997) Int J Comput Vis , vol.23 , Issue.1 , pp. 45-78
    • Smith, S.M.1    Brady, J.M.2
  • 19
    • 0036742197 scopus 로고    scopus 로고
    • Accurate, Robust, and Automated Longitudinal and Cross-Sectional Brain Change Analysis
    • Smith SM, Zhang Y, Jenkinson M, et al. Accurate, Robust, and Automated Longitudinal and Cross-Sectional Brain Change Analysis. NeuroImage 2002;17(1):479-89.
    • (2002) NeuroImage , vol.17 , Issue.1 , pp. 479-489
    • Smith, S.M.1    Zhang, Y.2    Jenkinson, M.3
  • 20
    • 0014834557 scopus 로고
    • Isolation of subpopulations of lymphocytic cells by the use of isotonically balanced solutions of Ficoll. I. Development of methods and demonstration of the existence of a large but finite number of subpopulations
    • Bach MK, Brashler JR. Isolation of subpopulations of lymphocytic cells by the use of isotonically balanced solutions of Ficoll. I. Development of methods and demonstration of the existence of a large but finite number of subpopulations. Exp Cell Res 1970;61(2):387-96.
    • (1970) Exp Cell Res , vol.61 , Issue.2 , pp. 387-396
    • Bach, M.K.1    Brashler, J.R.2
  • 21
    • 84865972258 scopus 로고    scopus 로고
    • The in vitro Effect of Oxidized LDL and PHA on Proliferation and Gene Expression of Regulatory T Cells in Patients with Atherosclerosis
    • Mottaghi A, Salehi E, Sezavar H, et al. The in vitro Effect of Oxidized LDL and PHA on Proliferation and Gene Expression of Regulatory T Cells in Patients with Atherosclerosis. Iran J Allergy Asthma Immunol 2012;11(3):217-23.
    • (2012) Iran J Allergy Asthma Immunol , vol.11 , Issue.3 , pp. 217-223
    • Mottaghi, A.1    Salehi, E.2    Sezavar, H.3
  • 22
    • 0036910671 scopus 로고    scopus 로고
    • The molar ratio of retinol-binding protein to transthyretin in the assessment of vitamin A status in adults. Proposal of a cut-off point
    • Zago LB, Dupraz H, Sarchi MI, et al. The molar ratio of retinol-binding protein to transthyretin in the assessment of vitamin A status in adults. Proposal of a cut-off point. Clin Chem Lab Med 2002;40(12):1301-7.
    • (2002) Clin Chem Lab Med , vol.40 , Issue.12 , pp. 1301-1307
    • Zago, L.B.1    Dupraz, H.2    Sarchi, M.I.3
  • 23
    • 79960989910 scopus 로고    scopus 로고
    • Multiple Sclerosis:Pathogenesis and Treatment
    • Loma I, Heyman R. Multiple Sclerosis:Pathogenesis and Treatment. Curr Neuropharmacol 2011;9(3):409-16.
    • (2011) Curr Neuropharmacol , vol.9 , Issue.3 , pp. 409-416
    • Loma, I.1    Heyman, R.2
  • 24
    • 73349109145 scopus 로고    scopus 로고
    • Th1, Th17 and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
    • Jäger A, Dardalhon V, Sobel RA, et al. Th1, Th17 and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J Immunol 2009;183(11):7169-77.
    • (2009) J Immunol , vol.183 , Issue.11 , pp. 7169-7177
    • Jäger, A.1    Dardalhon, V.2    Sobel, R.A.3
  • 25
    • 74249092274 scopus 로고    scopus 로고
    • Multiple sclerosis pharmacogenomics:Maximizing efficacy of therapy
    • Pappas DJ, Oksenberg JR. Multiple sclerosis pharmacogenomics:maximizing efficacy of therapy. Neurology 2010;74(1):S62-9.
    • (2010) Neurology , vol.74 , Issue.1
    • Pappas, D.J.1    Oksenberg, J.R.2
  • 26
    • 79952740974 scopus 로고    scopus 로고
    • Essential Role for Retinoic Acid in the Promotion of CD4(+) T Cell Effector Responses via Retinoic Acid Receptor Alpha
    • Hall JA, Cannons JL, Grainger JR, et al. Essential Role for Retinoic Acid in the Promotion of CD4(+) T Cell Effector Responses via Retinoic Acid Receptor Alpha. Immunity 2011;34(3):435-47.
    • (2011) Immunity , vol.34 , Issue.3 , pp. 435-447
    • Hall, J.A.1    Cannons, J.L.2    Grainger, J.R.3
  • 27
    • 84655169923 scopus 로고    scopus 로고
    • Vitamin A and immune regulation: Role of retinoic acid in gutassociated dendritic cell education, immune protection and tolerance
    • Cassani B, Villablanca EJ, De Calisto J, et al. Vitamin A and immune regulation: Role of retinoic acid in gutassociated dendritic cell education, immune protection and tolerance. Mol Aspects Med 2012;33(1):63-76.
    • (2012) Mol Aspects Med , vol.33 , Issue.1 , pp. 63-76
    • Cassani, B.1    Villablanca, E.J.2    De Calisto, J.3
  • 28
    • 84870221789 scopus 로고    scopus 로고
    • The Effect of Vitamin A Supplementation on Stimulated T-cell Proliferation with Myelin Oligodendrocyte Glycoprotein in Patients with Multiple Sclerosis
    • Jafarirad S, Siassi F, Harirchian MH, et al. The Effect of Vitamin A Supplementation on Stimulated T-cell Proliferation with Myelin Oligodendrocyte Glycoprotein in Patients with Multiple Sclerosis. J Neurosci Rural Pract 2012;3(3):294-8.
    • (2012) J Neurosci Rural Pract , vol.3 , Issue.3 , pp. 294-298
    • Jafarirad, S.1    Siassi, F.2    Harirchian, M.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.