메뉴 건너뛰기




Volumn 74, Issue 1 SUPPL., 2010, Pages

Multiple sclerosis pharmacogenomics: Maximizing efficacy of therapy

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BETA1A INTERFERON; EXTAVIA; GLATIRAMER; INTERFERON BETA SERINE; MITOXANTRONE; NATALIZUMAB; UNCLASSIFIED DRUG;

EID: 74249092274     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181c980fb     Document Type: Article
Times cited : (29)

References (55)
  • 4
    • 34250205988 scopus 로고    scopus 로고
    • Pharmacogenomics of Type i interferon therapy: A survey of response-modifying genes
    • DOI 10.1016/j.cytogfr.2007.04.012, PII S1359610107000391
    • O'Doherty C, Villoslada P, Vandenbroeck K. Pharmacogenomics of type I interferon therapy: a survey of response-modifying genes. Cytokine Growth Factor Rev 2007; 18: 211-222. (Pubitemid 46900903)
    • (2007) Cytokine and Growth Factor Reviews , vol.18 , Issue.3-4 , pp. 211-222
    • O'Doherty, C.1    Villoslada, P.2    Vandenbroeck, K.3
  • 5
    • 53049095928 scopus 로고    scopus 로고
    • Translation towards personalized medicine in multiple sclerosis
    • Miller A, Avidan N, Tzunz-Henig N, et al. Translation towards personalized medicine in multiple sclerosis. J Neurol Sci 2008;274:68-75.
    • (2008) J Neurol Sci , vol.274 , pp. 68-75
    • Miller, A.1    Avidan, N.2    Tzunz-Henig, N.3
  • 7
    • 58449087380 scopus 로고    scopus 로고
    • Defining multiple sclerosis treatment response with magnetic resonance imaging: How much activity is too much?
    • Giacomini PS, Arnold. DL, Bar-Or A, Antel JP. Defining multiple sclerosis treatment response with magnetic resonance imaging: how much activity is too much? Arch Neurol 2009;66:19-20.
    • (2009) Arch Neurol , vol.66 , pp. 19-20
    • Giacomini, P.S.1    Arnold, D.L.2    Bar-Or, A.3    Antel, J.P.4
  • 8
    • 30644475234 scopus 로고    scopus 로고
    • Defining the response to multiple sclerosis treatment: The role of conventional magnetic resonance imaging
    • Rovaris M, Filippi M. Defining the response to multiple sclerosis treatment: the role of conventional magnetic resonance imaging. Neurol Sci 2006;26(suppl 4):S204-S208.
    • (2006) Neurol Sci , vol.26 , Issue.SUPPL. 4
    • Rovaris, M.1    Filippi, M.2
  • 9
    • 48349102333 scopus 로고    scopus 로고
    • Important sources of variability in clinical studies of neutralizing antibodies against interferon beta
    • Hurwitz BJ. Important sources of variability in clinical studies of neutralizing antibodies against interferon beta. J Neurol Sci 2008;272:8-19.
    • (2008) J Neurol Sci , vol.272 , pp. 8-19
    • Hurwitz, B.J.1
  • 10
    • 12344257704 scopus 로고    scopus 로고
    • Neuropatliobiology of multiple sclerosis
    • vi-vii.
    • Peterson JW, Trapp BD. Neuropatliobiology of multiple sclerosis. Neurol Clin 2005;23:107-129, vi-vii.
    • (2005) Neurol Clin , vol.23 , pp. 107-129
    • Peterson, J.W.1    Trapp, B.D.2
  • 12
    • 0029897746 scopus 로고    scopus 로고
    • Side effect profile of interferon beta-1b in MS: Results of an open label trial
    • Neilley LK, Goodin DS, Goodkin DE, Hauser SL. Side effect profile of interferon beta-1b in MS: results of an open label trial. Neurology 1996;46:552-554.
    • (1996) Neurology , vol.46 , pp. 552-554
    • Neilley, L.K.1    Goodin, D.S.2    De Goodkin3    Hauser, S.L.4
  • 13
    • 0036690536 scopus 로고    scopus 로고
    • Review: IFN-α/β receptor interactions to biologic outcomes: Understanding the circuitry
    • Brierley MM, Fish EN. Review: IFN-α/β receptor interactions to biologic outcomes: understanding the circuitry. J Interferon Cytokine Res 2002;22:835-845.
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 835-845
    • Brierley, M.M.1    Fish, E.N.2
  • 14
    • 0038071786 scopus 로고    scopus 로고
    • The dinucleotide microsatellite polymorphism of the IFNAR1 gene promoter correlates with responsiveness of hepatitis C patients to interferon
    • DOI 10.1016/S1386-6346(02)00269-3, PII S1386634602002693
    • Matsuyama N, Mishiro S, Sugimoto M, et al. The dinucleotide microsatellite polymorphism of the IFNAR1 gene promoter correlates with responsiveness of hepatitis C patients to interferon. Hepatol Res 2003;25:221-225. (Pubitemid 36546347)
    • (2003) Hepatology Research , vol.25 , Issue.3 , pp. 221-225
    • Matsuyama, N.1    Mishiro, S.2    Sugimoto, M.3    Furuichi, Y.4    Hashimoto, M.5    Hijikata, M.6    Ohta, Y.7
  • 18
    • 68549085471 scopus 로고    scopus 로고
    • Genomewide scan of 500,000 single-nucleotide polymorphisms among respondcrs and nonresponders to interferon beta therapy in multiple sclerosis
    • Comabella M, Craig DW, Morcillo-Suárez C, et al. Genomewide scan of 500,000 single-nucleotide polymorphisms among respondcrs and nonresponders to interferon beta therapy in multiple sclerosis. Arch Neurol 2009;66:972-978.
    • (2009) Arch Neurol , vol.66 , pp. 972-978
    • Comabella, M.1    Craig, D.W.2    Morcillo-Suárez, C.3
  • 19
    • 40849094272 scopus 로고    scopus 로고
    • Genome-wide pharmacogcnomic analysis of the response to interferon β therapy in multiple sclerosis
    • Byun E, Caillier SJ, Montalban X, et al. Genome-wide pharmacogcnomic analysis of the response to interferon β therapy in multiple sclerosis. Arch Neurol 2008;65:337-344.
    • (2008) Arch Neurol , vol.65 , pp. 337-344
    • Byun, E.1    Caillier, S.J.2    Montalban, X.3
  • 23
    • 33747115709 scopus 로고    scopus 로고
    • Anti-inflammatory properties of type i interferons
    • Billiau A. Anti-inflammatory properties of type I interferons. Antiviral Res 2006;71:108-116.
    • (2006) Antiviral Res , vol.71 , pp. 108-116
    • Billiau, A.1
  • 24
    • 84983726619 scopus 로고    scopus 로고
    • Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: A pilot study
    • DOI 10.1053/jhep.2002.37198
    • King JK, Yeh SH, Lin MW, et al. Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: a pilot study. Hepatology 2002;36: 1416-1424. (Pubitemid 35403532)
    • (2002) Hepatology , vol.36 , Issue.6 , pp. 1416-1424
    • King, J.K.1    Yeh, S.-H.2    Lin, M.-W.3    Liu, C.-J.4    Lai, M.-Y.5    Kao, J.-H.6    Chen, D.-S.7    Chen, P.-J.8
  • 25
    • 33845903829 scopus 로고    scopus 로고
    • Pharmacogenetics of MXA SNPs in interferon-β treated multiple sclerosis patients
    • DOI 10.1016/j.jneuroim.2006.10.011, PII S0165572806003961
    • Weinstock-Guttman B, Tamaño-Blanco M, Bhasi K, Zivadinov R, Ramanathan M. Pharmacogenetics of MXA SNPs in interferon-β treated multiple sclerosis patients. J Neuroimmunol 2007;182:236-239. (Pubitemid 46026717)
    • (2007) Journal of Neuroimmunology , vol.182 , Issue.1-2 , pp. 236-239
    • Weinstock-Guttman, B.1    Tamano-Blanco, M.2    Bhasi, K.3    Zivadinov, R.4    Ramanathan, M.5
  • 26
    • 57249089060 scopus 로고    scopus 로고
    • The role of interferon b in regulation of CD4+ T-cells and its clinical implications
    • Chen J, Liu X. The role of interferon b in regulation of CD4+ T-cells and its clinical implications. Cell Immunol 2009;254:85-90.
    • (2009) Cell Immunol , vol.254 , pp. 85-90
    • Chen, J.1    Liu, X.2
  • 27
    • 33644961793 scopus 로고    scopus 로고
    • An IFNG polymorphism is associated with interferon-beta response in Spanish MS patients
    • Martínez A, de las Heras V, Mas Fontao A, et al. An IFNG polymorphism is associated with interferon-beta response in Spanish MS patients. J Neuroimmunol 2006;173:196-199.
    • (2006) J Neuroimmunol , vol.173 , pp. 196-199
    • Martínez, A.1    De Las Heras, V.2    Mas Fontao, A.3
  • 29
    • 0032769836 scopus 로고    scopus 로고
    • Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa
    • DOI 10.1002/hep.510300207
    • Edwards-Smith CJ, Jonsson JR, Purdie DM, Bansal A, Shorthouse C, Powell EE. Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa. Hepatology 1999;30:526-530. (Pubitemid 29357520)
    • (1999) Hepatology , vol.30 , Issue.2 , pp. 526-530
    • Edwards-Smith, C.J.1    Jonsson, J.R.2    Purdie, D.M.3    Bansal, A.4    Shorthouse, C.5    Powell, E.E.6
  • 30
    • 0035123858 scopus 로고    scopus 로고
    • Interleukin 10 polymorphisms as predictors of sustained response in antiviral therapy for chronic hepatitis C infection
    • DOI 10.1053/jhep.2001.22347
    • Yee LJ, Tang J, Gibson AW, Kimberly R, Van Leeuwen DJ, Kaslow RA. Interleukin 10 polymorphisms as predictors of sustained response in antiviral therapy for chronic hepatitis C infection. Hepatology 2001;33:708-712. (Pubitemid 32185234)
    • (2001) Hepatology , vol.33 , Issue.3 , pp. 708-712
    • Yee, L.J.1    Tang, J.2    Gibson, A.W.3    Kimberly, R.4    Van Leeuwen, D.J.5    Kaslow, R.A.6
  • 31
    • 30444455025 scopus 로고    scopus 로고
    • Effect of cytokine gene polymorphism on histological activity index, viral load and response to treatment in patients with chronic hepatitis C genotype 3
    • Abbas Z, Moatter T, Hussainy A, Jafri W. Effect of cytokine gene polymorphism on histological activity index, viral load and response to treatment in patients with chronic hepatitis C genotype 3. World J Gastroenterol 2005;11: 6656-6661. (Pubitemid 43072706)
    • (2005) World Journal of Gastroenterology , vol.11 , Issue.42 , pp. 6656-6661
    • Abbas, Z.1    Moatter, T.2    Hussainy, A.3    Jafri, W.4
  • 33
    • 49149116386 scopus 로고    scopus 로고
    • Early identification of interferon-beta responders by ex vivo testing in patients with multiple sclerosis
    • Wiesemann E, Deb M, Hemmer B, Radeke HH, Windhagen A. Early identification of interferon-beta responders by ex vivo testing in patients with multiple sclerosis. Clin Immunol 2008;128:306-313.
    • (2008) Clin Immunol , vol.128 , pp. 306-313
    • Wiesemann, E.1    Deb, M.2    Hemmer, B.3    Radeke, H.H.4    Windhagen, A.5
  • 34
    • 59949106172 scopus 로고    scopus 로고
    • Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis
    • Trapp BD, Stys PK. Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis. Lancet Neurol 2009;8:280-291.
    • (2009) Lancet Neurol , vol.8 , pp. 280-291
    • Trapp, B.D.1    Stys, P.K.2
  • 35
    • 33751540077 scopus 로고    scopus 로고
    • Interferon-beta and neuroprotection in multiple sclerosis - Facts, hopes and phantasies
    • Kieseier BC, Hartung HP. Interferon-beta and neuroprotection in multiple sclerosis - facts, hopes and phantasies. Exp Neurol 2007;203:1-4.
    • (2007) Exp Neurol , vol.203 , pp. 1-4
    • Kieseier, B.C.1    Hartung, H.P.2
  • 36
    • 69549135691 scopus 로고    scopus 로고
    • Glypican 5 is an interferon-beta response gene: A replication study
    • Cénit MD, Bianco-Kelly F, de las Heras V, et al. Glypican 5 is an interferon-beta response gene: a replication study. Mult Scler 2009;15:913-917.
    • (2009) Mult Scler , vol.15 , pp. 913-917
    • Cénit, M.D.1    Bianco-Kelly, F.2    De Las Heras, V.3
  • 38
    • 56349127789 scopus 로고    scopus 로고
    • Genomic effects of once-weekly, intramuscular interferon-β1a treatment after the first dose and on chronic dosing: Relationships to 5-year clinical outcomes in multiple sclerosis patients
    • Weinstock-Guttman B, Bhasi K, Badgett D, et al. Genomic effects of once-weekly, intramuscular interferon-β1a treatment after the first dose and on chronic dosing: relationships to 5-year clinical outcomes in multiple sclerosis patients. J Neuroimmunol 2008;205:113-125.
    • (2008) J Neuroimmunol , vol.205 , pp. 113-125
    • Weinstock-Guttman, B.1    Bhasi, K.2    Badgett, D.3
  • 39
    • 39849089879 scopus 로고    scopus 로고
    • Natalizumab alters transcriptional expression profiles of blood cell subpopulations of multiple sclerosis patients
    • Lindberg RL, Achtnichts L, Hoffmann F, Kuhle J, Kappos L. Natalizumab alters transcriptional expression profiles of blood cell subpopulations of multiple sclerosis patients. J Neuroimmunol 2008;194:153-164.
    • (2008) J Neuroimmunol , vol.194 , pp. 153-164
    • Lindberg, R.L.1    Achtnichts, L.2    Hoffmann, F.3    Kuhle, J.4    Kappos, L.5
  • 40
    • 72649106903 scopus 로고    scopus 로고
    • A type i interferon signature in monocytes is associated with poor response to interferon-{beta} in multiple sclerosis
    • Sep 9.
    • Comabella M, Lünemann JD, Río J, et al. A type I interferon signature in monocytes is associated with poor response to interferon-{beta} in multiple sclerosis. Brain Epub 2009 Sep 9.
    • (2009) Brain Epub
    • Comabella, M.1    Lünemann, J.D.2    Río, J.3
  • 41
    • 43049177588 scopus 로고    scopus 로고
    • Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
    • Prinz M, Schmidt H, Mildner A, et al. Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity 2008;28:675-686.
    • (2008) Immunity , vol.28 , pp. 675-686
    • Prinz, M.1    Schmidt, H.2    Mildner, A.3
  • 42
    • 40349089507 scopus 로고    scopus 로고
    • Glatiramer acetate: Evidence for a dual mechanism of action
    • DOI 10.1007/s00415-008-1005-5
    • Blanchette F, Neuhaus O. Glatiramer acetate: evidence for a dual mechanism of action. J Neurol 2008; 255(suppl 1):26-36. (Pubitemid 351341870)
    • (2008) Journal of Neurology , vol.255 , Issue.SUPPL. 1 , pp. 26-36
    • Blanchette, F.1    Neuhaus, O.2
  • 43
    • 0015103005 scopus 로고
    • Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide
    • Teitelbaum D, Meshorer A, Hirshfeld T, Arnon R, Sela M. Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide. Eur J Immunol 1971;1:242-248.
    • (1971) Eur J Immunol , vol.1 , pp. 242-248
    • Teitelbaum, D.1    Meshorer, A.2    Hirshfeld, T.3    Arnon, R.4    Sela, M.5
  • 47
    • 67349274390 scopus 로고    scopus 로고
    • HLA class i and II alleles and response to treatment with interferon-beta in relapsing-remitting multiple sclerosis
    • Comabella M, Fernández-Arquero M, Río J, et al. HLA class I and II alleles and response to treatment with interferon-beta in relapsing-remitting multiple sclerosis. J Neuroimmunol 2009;210:116-119.
    • (2009) J Neuroimmunol , vol.210 , pp. 116-119
    • Comabella, M.1    Fernández-Arquero, M.2    Río, J.3
  • 48
    • 34447536807 scopus 로고    scopus 로고
    • Clinical response to glatiramer acetate correlates with modulation of IFN-γ and IL-4 expression in multiple sclerosis
    • DOI 10.1177/1352458506074510
    • Valenzuela RM, Costello K, Chen M, Said A, Johnson KP, Dhib-Jalbut S. Clinical response to glatiramer acetate correlates with modulation of IFN-γ and IL-4 expression in multiple sclerosis. Mult Scler 2007;13:754-762. (Pubitemid 47074099)
    • (2007) Multiple Sclerosis , vol.13 , Issue.6 , pp. 754-762
    • Valenzuela, R.M.1    Costello, K.2    Chen, M.3    Said, A.4    Johnson, K.P.5    Dhib-Jalbut, S.6
  • 50
    • 33845655480 scopus 로고    scopus 로고
    • Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2
    • DOI 10.1111/j.1349-7006.2006.00371.x
    • Tamura A, Wakabayashi K, Onishi Y, et al. Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2. Cancer Sci 2007;98:231-239. (Pubitemid 44941876)
    • (2007) Cancer Science , vol.98 , Issue.2 , pp. 231-239
    • Tamura, A.1    Wakabayashi, K.2    Onishi, Y.3    Takeda, M.4    Ikegami, Y.5    Sawada, S.6    Tsuji, M.7    Matsuda, Y.8    Ishikawa, T.9
  • 51
    • 34250888210 scopus 로고    scopus 로고
    • Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs
    • Nayak MS, Yang JM, Hait WN. Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs. Cancer Res 2007;67:5831-5839.
    • (2007) Cancer Res , vol.67 , pp. 5831-5839
    • Nayak, M.S.1    Yang, J.M.2    Hait, W.N.3
  • 52
    • 10844228995 scopus 로고    scopus 로고
    • Multidrug transporter activity in lymphocytes
    • Elliott JI, Raguz S, Higgins CF. Multidrug transporter activity in lymphocytes. Br J Pharmacol 2004;143:899-907.
    • (2004) Br J Pharmacol , vol.143 , pp. 899-907
    • Elliott, J.I.1    Raguz, S.2    Higgins, C.F.3
  • 53
    • 1542786385 scopus 로고    scopus 로고
    • Molecular control of the cell cycle in cancer: Biological and clinical aspects
    • Moller MB. Molecular control of the cell cycle in cancer: biological and clinical aspects. Dan Med Bull 2003;50: 118-138.
    • (2003) Dan Med Bull , vol.50 , pp. 118-138
    • Moller, M.B.1
  • 54
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin
    • Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin. Nature 1992;356:63-66.
    • (1992) Nature , vol.356 , pp. 63-66
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6
  • 55
    • 43249103954 scopus 로고    scopus 로고
    • Getting specific: Monoclonal antibodies in multiple sclerosis
    • DOI 10.1016/S1474-4422(08)70110-8, PII S1474442208701108
    • Lutterotti A, Martin R. Getting specific: monoclonal antibodies in multiple sclerosis. Lancet Neurol 2008;7:538-547. (Pubitemid 351657494)
    • (2008) The Lancet Neurology , vol.7 , Issue.6 , pp. 538-547
    • Lutterotti, A.1    Martin, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.