Retinoic acid promotes the development of Th2-like human myelin basic protein-reactive T cells

Cellular Immunology

Volumn 215, Issue 1, 2002, Pages 54-60

  Lovett Racke, Amy E ^a   Racke, Michael K ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 4; MYELIN BASIC PROTEIN; RETINOIC ACID;

ALLERGIC ENCEPHALOMYELITIS; ARTICLE; CASE REPORT; CELL ASSAY; CELL LINE; CELL MATURATION; CELL PROLIFERATION; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; DRUG SAFETY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MULTIPLE SCLEROSIS; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TH1 CELL; TH2 CELL; TREATMENT INDICATION;

AUTOANTIGENS; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; RNA, MESSENGER; TH1 CELLS; TH2 CELLS; TRETINOIN;

ANIMALIA;

EID: 0036348902     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-8749(02)00013-8     Document Type: Article

References (36)

1. T cells responsive to myelin basic protein in patients with multiple sclerosis
2. Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients
3. Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation
4. HPRT mutant T-cell lines from multiple sclerosis patients recognize myelin proteolipid protein peptides
5. Suppression of experimental allergic encephalomyelitis by retinoic acid
6. Immunosuppressive activity of 13-cis-retinoic acid and prevention of experimental autoimmune encephalomyelitis in rats
7. Retinoid treatment of experimental allergic encephalomyelitis: IL-4 production correlates with improved disease course
8. Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease
9. Longitudinal study of myelin basic protein-specific T-cell receptors during the course of multiple sclerosis
10. An investigation approach to disease therapy in multiple sclerosis
11. Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: Requirement of Lyt1+2-T lymphocytes
12. Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis
13. Bronchospasm induced by isotretinoin
14. Exacerbation of asthma by isothetinoin
15. Tolerability of the synthetic retinoid fenretinide (HPR)
16. Phase II study of fenretinide (N-[4-hydroxyphenyl]retinamide) in advanced breast cancer and melanoma
17. Long-term tolerability of fenretinide 4-HPR in breast cancer patients
18. Regulation of disease susceptibility: Decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis
19. 3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis
20. 3
21. 3 has a direct effect on naïve CD4+ T cells to enhance the development of Th2 cells
22. 3 inhibits dendritic cell differentiation and maturation in vitro
23. Potent inhibition of dendritic cell differentiation and maturation by vitamin D analogs
24. 3 inhibits differentiation, maturation, activation, survival of dendritic cells leading to impaired alloreactive T cell activation
25. 3 affects differentiation, maturation, function of human monocyte-derived dendritic cells
26. 3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo
27. Current disease-modifying therapies in multiple sclerosis
28. Vitamin A and retinoids: From nutrition to pharmacotherapy in dermatology and oncology
29. Vitamin A and retinoids in health and medicine
30. Cellular biology and biochemistry of the retinoids
31. 13-cis-retinoic acid plus interferon alpha-2a: Highly active systemic therapy for squamous cell carcinoma of the cervix
32. 13-cis-retinoic acid and interferon alpha-2a: Effective combination therapy for advanced squamous cell carcinoma of the skin
33. Synergistic effect of retinoids and interferon alpha on tumor-induced angiogenesis: Anti-angiogenic effect on HPV-harboring tumor-cell lines
34. Modulation of interferon (IFN)-inducible gene expression by retinoic acid: Upregulation of STAT1 protein in IFN-unresponsive cells
35. All-trans-retinoic acid potentiates the ability of interferon beta-1b to augment suppressor cell function in multiple sclerosis
36. Etretinate augments interferon beta-1b effects on suppressor cells in multiple sclerosis