An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating il-1 production in dendritic cells

Nature Communications

Volumn 5, Issue , 2014, Pages

  Yasukawa, Shinsuke ^a,b   Miyazaki, Yoshiyuki ^a   Yoshii, Chika ^b   Nakaya, Mako ^a   Ozaki, Naoko ^a,c   Toda, Shuji ^a   Kuroda, Etsushi ^d   Ishibashi, Ken Ichi ^e   Yasuda, Tomoharu ^f   Natsuaki, Yohei ^g   Mi Ichi, Fumika ^a   Iizasa, Eíichi ^a   Nakahara, Takeshi ^b   Yamazaki, Masanori ^a   Kabashima, Kenji ^g   Iwakura, Yoichiro ^h   Takai, Toshiyuki ⁱ   Saito, Takashi ^f   Kurosaki, Tomohiro ^d,f   Malissen, Bernard ^j   Ohno, Naohito ^e   Furue, Masutaka ^b   Yoshida, Hiroki ^a   Hara, Hiromitsu ^a   more..

^a SAGA UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c NIPPON BOEHRINGER INGELHEIM CO LTD   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^f RIKEN Center for Integrative Medical Sciences   (Japan)

^g KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^h TOKYO UNIVERSITY OF SCIENCE   (Japan)

ⁱ TOHOKU UNIVERSITY   (Japan)

^j CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; CASPASE RECRUITMENT DOMAIN CONTAINING PROTEIN 9; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 17; INTERLEUKIN 1BETA CONVERTING ENZYME; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASE SYK; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; BCL10 PROTEIN, MOUSE; CARD9 PROTEIN, MOUSE; CARRIER PROTEIN; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CIAS1 PROTEIN, MOUSE; IL1R1 PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR TYPE I; MYD88 PROTEIN, MOUSE; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TYROBP PROTEIN, MOUSE;

ALLERGY; CELL ORGANELLE; ENZYME ACTIVITY; IMMUNE SYSTEM; PROTEIN; SECRETION; SIGNAL;

ANTIGEN PRESENTING CELL; ARTICLE; CELL DIFFERENTIATION; CONTACT ALLERGY; CONTACT SENSITIZATION; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE SEVERITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; SIGNAL TRANSDUCTION; SYNTHESIS; T LYMPHOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CD8+ T LYMPHOCYTE; CONTACT DERMATITIS; GENETICS; IMMUNOLOGY; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; KNOCKOUT MOUSE; METABOLISM; MOUSE; SECRETION (PROCESS);

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARD SIGNALING ADAPTOR PROTEINS; CARRIER PROTEINS; CASPASE 1; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; DERMATITIS, CONTACT; ENZYME ACTIVATION; IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIF; INFLAMMASOMES; INTERLEUKIN-1; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; RECEPTORS, INTERLEUKIN-1 TYPE I; SIGNAL TRANSDUCTION;

EID: 84899999711     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4755     Document Type: Article

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